Research graph
References from Decoupling metabolic defense: Mutational and recombinational chaos in Sod1-deficient cells. Local targets link to admitted publications; unresolved targets remain external evidence.
Antioxidants: a comprehensive review
10.1007/s00204-025-03997-2 · 2025 · External reference
Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression
10.1016/s0891-5849(02)00905-x · 2002 · External reference
Amyotrophic lateral sclerosis: copper/zinc superoxide dismutase (SOD1) gene mutations
10.1016/s0960-8966(99)00071-1 · 2000 · External reference
Current potential pathogenic mechanisms of copper-zinc superoxide dismutase 1 (SOD1) in amyotrophic lateral sclerosis
10.1515/revneuro-2024-0010 · 2024 · External reference
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
10.1038/362059a0 · 1993 · External reference
Characterization of the activity, aggregation, and toxicity of heterodimers of WT and ALS-associated mutant Sod1
10.1073/pnas.1902483116 · 2019 · External reference
Multifaceted roles of superoxide dismutases (SODs) in cellular homeostasis and cancer progression: Redox regulation and therapeutic implications
10.5937/jomb0-59010 · 2026 · External reference
Nuclear SOD1 in Growth Control, Oxidative Stress Response, Amyotrophic Lateral Sclerosis, and Cancer
10.3390/antiox11020427 · 2022 · External reference
CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life
10.1038/sj.onc.1208207 · 2005 · External reference
Inactivation of homocitrate synthase causes lysine auxotrophy in copper/zinc-containing superoxide dismutase-deficient yeast Schizosaccharomyces pombe
10.1074/jbc.m506611200 · 2006 · External reference
Oxidative stress responses of the yeast Saccharomyces cerevisiae
10.1002/(sici)1097-0061(199812)14:16<1511::aid-yea356>3.0.co;2-s · 1998 · External reference
Yeast lacking superoxide dismutase. Isolation of genetic suppressors
10.1016/s0021-9258(19)36959-5 · 1992 · External reference
Superoxide dismutase 1 acts as a nuclear transcription factor to regulate oxidative stress resistance
10.1038/ncomms4446 · 2014 · External reference
New links between SOD1 and metabolic dysfunction from a yeast model of amyotrophic lateral sclerosis
10.1242/jcs.190298 · 2016 · External reference
SOD1 Phosphorylation by mTORC1 Couples Nutrient Sensing and Redox Regulation
10.1016/j.molcel.2018.03.029 · 2018 · External reference
Genome-wide analysis of genomic alterations induced by oxidative DNA damage in yeast
10.1093/nar/gkz027 · 2019 · External reference
A genomewide screen in Saccharomyces cerevisiae for genes that suppress the accumulation of mutations
10.1073/pnas.2035018100 · 2003 · External reference
Mutational signatures of redox stress in yeast single-strand DNA and of aging in human mitochondrial DNA share a common feature
10.1371/journal.pbio.3000263 · 2019 · External reference
Genome-wide mapping of spontaneous genetic alterations in diploid yeast cells
10.1073/pnas.2018633117 · 2020 · External reference
Genome sequencing and genetic breeding of a bioethanol Saccharomyces cerevisiae strain YJS329
10.1186/1471-2164-13-479 · 2012 · External reference
The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements
10.1016/s0092-8674(02)00614-1 · 2002 · External reference
Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation
10.1371/journal.pbio.3000464 · 2019 · External reference
Genome-wide high-resolution mapping of UV-induced mitotic recombination events in Saccharomyces cerevisiae
2013 · External reference
The genetic basis of aneuploidy tolerance in wild yeast
10.7554/elife.52063 · 2020 · External reference
Saccharomyces cerevisiae SSD1-V confers longevity by a Sir2p-independent mechanism
10.1093/genetics/166.4.1661 · 2004 · External reference
DNA oxidation matters: the HPLC-electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine
10.1073/pnas.95.1.288 · 1998 · External reference
Oxidative decay of DNA
10.1074/jbc.272.32.19633 · 1997 · External reference
Fidelity of nucleotide insertion at 8-oxo-7,8-dihydroguanine by mammalian DNA polymerase δ: steady-state and pre-steady-state kinetic analysis
10.1074/jbc.m006696200 · 2001 · External reference
Translesion synthesis of 7,8-dihydro-8-oxo-2′-deoxyguanosine by DNA polymerase eta in vivo
2008 · External reference
Freedom to err: The expanding cellular functions of translesion DNA polymerases
10.1016/j.molcel.2023.07.008 · 2023 · External reference
Uncovering Bleomycin-Induced Genomic Alterations and Underlying Mechanisms in the Yeast Saccharomyces cerevisiae
2022 · External reference
Yeast Rev1 protein is a G template-specific DNA polymerase
10.1074/jbc.m112146200 · 2002 · External reference
Complex formation with Rev1 enhances the proficiency of Saccharomyces cerevisiae DNA polymerase zeta for mismatch extension and for extension opposite from DNA lesions
10.1128/mcb.01671-06 · 2006 · External reference
Variability in SOD1-associated amyotrophic lateral sclerosis: geographic patterns, clinical heterogeneity, molecular alterations, and therapeutic implications
10.1186/s40035-024-00416-x · 2024 · External reference
High-resolution mapping of spontaneous mitotic recombination hotspots on the 1.1 Mb arm of yeast chromosome IV
10.1371/journal.pgen.1003434 · 2013 · External reference
Spontaneous and environment induced genomic alterations in yeast model
2024 · External reference
DNA strand breaking by the hydroxyl radical is governed by the accessible surface areas of the hydrogen atoms of the DNA backbone
10.1073/pnas.95.17.9738 · 1998 · External reference
The Two Faces of Reactive Oxygen Species in Cancer
10.1146/annurev-cancerbio-041916-065808 · 2017 · External reference
SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer
10.1038/s41467-021-22480-x · 2021 · External reference
Targeting SOD1 reduces experimental non–small-cell lung cancer
10.1172/jci71714 · 2014 · External reference
Living on the Edge: ROS Homeostasis in Cancer Cells and Its Potential as a Therapeutic Target
10.3390/antiox14081002 · 2025 · External reference
Structural similarity of wild-type and ALS-mutant superoxide dismutase-1 fibrils using limited proteolysis and atomic force microscopy
10.1073/pnas.1309613110 · 2013 · External reference
From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS
10.1038/35097565 · 2001 · External reference
Disease-associated mutations at copper ligand histidine residues of superoxide dismutase 1 diminish the binding of copper and compromise dimer stability
10.1074/jbc.m604503200 · 2007 · External reference
Structural and biophysical properties of the pathogenic SOD1 variant H46R/H48Q
10.1021/bi8021735 · 2009 · External reference
SOD1 aggregation and ALS: role of metallation states and disulfide status
10.2174/1568026611212220010 · 2012 · External reference
Copper-zinc superoxide dismutase and amyotrophic lateral sclerosis
10.1146/annurev.biochem.72.121801.161647 · 2005 · External reference
Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method
10.1016/s0076-6879(02)50957-5 · 2002 · External reference
High-resolution genome-wide analysis of irradiated (UV and γ-rays) diploid yeast cells reveals a high frequency of genomic loss of heterozygosity (LOH) events
10.1534/genetics.111.137927 · 2012 · External reference
Genome-wide high-resolution mapping of UV-induced mitotic recombination events in Saccharomyces cerevisiae
2013 · External reference
Global analysis of genomic instability caused by DNA replication stress in Saccharomyces cerevisiae
2016 · External reference
Detection of “hidden” mitotic crossovers by long-read DNA sequencing
2026 · External reference
Fast and accurate short read alignment with Burrows-Wheeler transform
10.1093/bioinformatics/btp324 · 2009 · External reference
The Sequence Alignment/Map format and SAMtools
10.1093/bioinformatics/btp352 · 2009 · External reference
VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing
10.1101/gr.129684.111 · 2012 · External reference
GC content elevates mutation and recombination rates in the yeast Saccharomyces cerevisiae
10.1073/pnas.1807334115 · 2018 · External reference
Novel insights into the effects of 5-hydroxymethfurural on genomic instability and phenotypic evolution using a yeast model
2024 · External reference
Sumoylation of the DNA polymerase ε by the Smc5/6 complex contributes to DNA replication
10.1371/journal.pgen.1008426 · 2019 · External reference