References

Pervasive pleiotropy between psychiatric disorders and immune disorders revealed by integrative analysis of multiple GWAS

10.1007/s00439-015-1596-8 · 2015 · External reference

Autoimmune diseases and psychotic disorders

10.3389/fpsyt.2019.00131 · 2019 · External reference

An immunogenetic investigation of 30 autoimmune and autoinflammatory diseases and their links to psychiatric disorders in a nationwide sample

10.1111/imm.13597 · 2023 · External reference

Examining the genetic links between clusters of immune-mediated diseases and psychiatric disorders

10.1038/s41398-025-03470-9 · 2025 · External reference

Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk

10.1093/hmg/ddz145 · 2019 · External reference

Shared genetic basis and causality between schizophrenia and inflammatory bowel disease: Evidence from a comprehensive genetic analysis

2024 · External reference

Genetic correlation, shared loci, but no causality between bipolar disorder and inflammatory bowel disease: A genome-wide pleiotropic analysis

10.1016/j.jad.2023.12.042 · 2024 · External reference

Autoinflammatory diseases and cytokine storms—Imbalances of innate and adaptative immunity

10.3390/ijms222011241 · 2021 · External reference

Comparative analysis of cytokine profiles in autoinflammatory and autoimmune conditions

10.1016/j.cyto.2010.02.014 · 2010 · External reference

Autoinflammation and autoimmunity: Bridging the divide

10.1016/j.autrev.2012.07.018 · 2012 · External reference

The role of tumour necrosis factor in the pathogenesis of immune-mediated diseases

10.1177/03946320140270s101 · 2014 · External reference

Associations of depression with C-reactive protein, IL-1, and IL-6: A meta-analysis

10.1097/psy.0b013e3181907c1b · 2009 · External reference

Causal role of immune cells in generalized anxiety disorder: Mendelian randomization study

10.3389/fimmu.2023.1338083 · 2024 · External reference

Immune system abnormalities in schizophrenia: An integrative view and translational perspectives

10.3389/fpsyt.2022.880568 · 2022 · External reference

The immunology of bipolar disorder

10.1159/000356539 · 2014 · External reference

Peripheral blood inflammatory markers in patients with attention deficit/hyperactivity disorder (ADHD): A systematic review and meta-analysis

10.1016/j.pnpbp.2022.110581 · 2022 · External reference

Large-scale plasma proteomics comparisons through genetics and disease associations

10.1038/s41586-023-06563-x · 2023 · External reference

Genetic analysis of over half a million people characterises C-reactive protein loci

10.1038/s41467-022-29650-5 · 2022 · External reference

GWAS for autoimmune Addison’s disease identifies multiple risk loci and highlights AIRE in disease susceptibility

10.1038/s41467-021-21015-8 · 2021 · External reference

Investigating pleiotropy between depression and autoimmune diseases using the UK Biobank

10.1016/j.bpsgos.2021.03.002 · 2021 · External reference

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

10.1038/ng.3760 · 2017 · External reference

Interpreting type 1 diabetes risk with genetics and single-cell epigenomics

10.1038/s41586-021-03552-w · 2021 · External reference

Combined genetic analysis of juvenile idiopathic arthritis clinical subtypes identifies novel risk loci, target genes and key regulatory mechanisms

10.1136/annrheumdis-2020-218481 · 2021 · External reference

Identification of genetic risk loci and prioritization of genes and pathways for myasthenia gravis: A genome-wide association study

2022 · External reference

Transethnic analysis of psoriasis susceptibility in South Asians and Europeans enhances fine mapping in the MHC and genome wide

2022 · External reference

Comparative genetic analysis of psoriatic arthritis and psoriasis for the discovery of genetic risk factors and risk prediction modeling

10.1002/art.42154 · 2022 · External reference

Genetics of rheumatoid arthritis contributes to biology and drug discovery

10.1038/nature12873 · 2014 · External reference

Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus

10.1038/ng.3434 · 2015 · External reference

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

10.1038/s41593-018-0275-1 · 2018 · External reference

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

10.1038/s41588-019-0439-2 · 2019 · External reference

A major role for common genetic variation in anxiety disorders

10.1038/s41380-019-0559-1 · 2020 · External reference

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains

2023 · External reference

Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia

10.1186/s13229-017-0137-9 · 2017 · External reference

Genomics yields biological and phenotypic insights into bipolar disorder

10.1038/s41586-024-08468-9 · 2025 · External reference

A large-scale genome-wide association study meta-analysis of cannabis use disorder

10.1016/s2215-0366(20)30339-4 · 2020 · External reference

Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies

2025 · External reference

Revealing the complex genetic architecture of obsessive–compulsive disorder using meta-analysis

10.1038/mp.2017.154 · 2018 · External reference

Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium

10.1038/s41380-020-0677-9 · 2020 · External reference

Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder

2024 · External reference

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

10.1038/s41586-022-04434-5 · 2022 · External reference

Interrogating the genetic determinants of Tourette’s syndrome and other tic disorders through genome-wide association studies

10.1176/appi.ajp.2018.18070857 · 2019 · External reference

Transcriptome-wide structural equation modeling of 13 major psychiatric disorders for cross-disorder risk and drug repurposing

10.1001/jamapsychiatry.2023.1808 · 2023 · External reference

TNFR1 and TNFR2 in the control of the life and death balance of macrophages

10.3389/fcell.2019.00091 · 2019 · External reference

Tumor necrosis factor α– and interleukin‐1β–dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1

10.1002/art.37819 · 2013 · External reference

Rethinking IL-6 and CRP: Why they are more than inflammatory biomarkers, and why it matters

10.1016/j.bbi.2018.02.013 · 2018 · External reference

What does plasma CRP tell us about peripheral and central inflammation in depression?

10.1038/s41380-018-0096-3 · 2020 · External reference

Passage of cytokines across the blood-brain barrier

10.1159/000097202 · 1995 · External reference

Depression and inflammatory bowel disease: A bidirectional two-sample Mendelian randomization study

10.1093/ecco-jcc/jjab191 · 2022 · External reference

Depression and anxiety in inflammatory bowel disease: Epidemiology, mechanisms and treatment

10.1038/s41575-022-00634-6 · 2022 · External reference

From inflammation to sickness and depression: When the immune system subjugates the brain

10.1038/nrn2297 · 2008 · External reference

Cytokine effects on the basal ganglia and dopamine function: The subcortical source of inflammatory malaise

10.1016/j.yfrne.2012.09.003 · 2012 · External reference

The balance between IL-1 and IL-1Ra in disease

10.1016/s1359-6101(02)00020-5 · 2002 · External reference

The blood-brain barrier in systemic inflammation

10.1016/j.bbi.2016.03.010 · 2017 · External reference

Synaptic scaling mediated by glial TNF-alpha

10.1038/nature04671 · 2006 · External reference

Microglial TNF-α suppresses cocaine-induced plasticity and behavioral sensitization

10.1016/j.neuron.2016.03.030 · 2016 · External reference

Inflammatory mediators in major depression and bipolar disorder

10.1038/s41398-024-02921-z · 2024 · External reference

Associations of immunological proteins/traits with schizophrenia, major depression and bipolar disorder: A bi-directional two-sample mendelian randomization study

10.1016/j.bbi.2021.07.009 · 2021 · External reference

An integrated framework for local genetic correlation analysis

10.1038/s41588-022-01017-y · 2022 · External reference

Inflammatory biomarkers and risk of psychiatric disorders

10.1001/jamapsychiatry.2024.2185 · 2024 · External reference

Immune suppression and immune activation in depression

10.1016/j.bbi.2010.10.008 · 2011 · External reference

Inflammation and schizophrenia

10.1586/14737175.7.7.789 · 2007 · External reference

Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders

10.1016/j.psyneuen.2023.106368 · 2023 · External reference

C-reactive protein as a potential biomarker in psychiatric practice: Are we there yet?

10.1080/15622975.2021.1961502 · 2021 · External reference

Association of serum interleukin 6 and C-reactive protein in childhood with depression and psychosis in young adult life: A population-based longitudinal study

10.1001/jamapsychiatry.2014.1332 · 2014 · External reference

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types

10.1038/s41588-018-0081-4 · 2018 · External reference

Immune-targeted therapies for depression: Current evidence for antidepressant effects of monoclonal antibodies

2024 · External reference

What has GWAS done for HLA and disease associations?

10.1111/iji.12332 · 2017 · External reference

Human leukocyte antigen super-locus: Nexus of genomic supergenes, SNPs, indels, transcripts, and haplotypes

10.1038/s41439-022-00226-5 · 2022 · External reference

Current research status of HLA in immune-related diseases

10.1002/iid3.416 · 2021 · External reference

Unresolved reference

2024 · External reference

The X chromosome and sex-specific effects in infectious disease susceptibility

10.1186/s40246-018-0185-z · 2019 · External reference

The X-files in immunity: Sex-based differences predispose immune responses

10.1038/nri2394 · 2008 · External reference

Accounting for eXentricities: analysis of the X chromosome in GWAS reveals X-linked genes implicated in autoimmune diseases

10.1371/journal.pone.0113684 · 2014 · External reference

Sex representation in neurodegenerative and psychiatric disorders’ preclinical and clinical studies

10.1016/j.nbd.2023.106214 · 2023 · External reference

The inactive X chromosome as a female protector in autism and beyond

2026 · External reference

Minimal phenotyping yields genome-wide association signals of low specificity for major depression

10.1038/s41588-020-0594-5 · 2020 · External reference

Participation bias in the UK Biobank distorts genetic associations and downstream analyses

10.1038/s41562-023-01579-9 · 2023 · External reference

The role of aberrations in the immune-inflammatory response system (IRS) and the compensatory immune-regulatory reflex system (CIRS) in different phenotypes of schizophrenia: The IRS-CIRS theory of schizophrenia

10.1007/s12035-019-01737-z · 2020 · External reference

Inflammation in psychiatric disorders: What comes first?

10.1111/nyas.13712 · 2019 · External reference

An atlas of genetic correlations across human diseases and traits

10.1038/ng.3406 · 2015 · External reference

Pervasive downward bias in estimates of liability-scale heritability in genome-wide association study meta-analysis: A simple solution

10.1016/j.biopsych.2022.05.029 · 2023 · External reference

Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits

10.1038/s41562-019-0566-x · 2019 · External reference

Unresolved reference

2024 · External reference

Construction and validation of a self-direction measure for mental health care

10.1002/jclp.23091 · 2021 · External reference

Rethinking IL-6 and CRP: Why they are more than inflammatory biomarkers, and why it matters

10.1016/j.bbi.2018.02.013 · 2018 · External reference

The genomic architecture of circulating cytokine levels points to drug targets for immune-related diseases

10.1038/s42003-025-07453-w · 2025 · External reference

Pleiotropic genetic architecture and novel loci for C-reactive protein levels

10.1038/s41467-022-34688-6 · 2022 · External reference

The MR-Base platform supports systematic causal inference across the human phenome

10.7554/elife.34408 · 2018 · External reference