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References from A machine learning-derived aging index for risk stratification and mortality prediction in cardiovascular-kidney-metabolic syndrome: A retrospective cohort study. Local targets link to admitted publications; unresolved targets remain external evidence.
Cardiovascular-kidney-metabolic health: a presidential advisory from the American Heart Association
10.1161/cir.0000000000001184 · 2023 · External reference
The cardiovascular-kidney-metabolic health framework: implications for nephrology
10.2215/cjn.0000000744 · 2025 · External reference
Cardiovascular-Kidney-Metabolic (CKM) syndrome: a case-based narrative review
10.1016/j.ajmo.2025.100089 · 2025 · External reference
Role of oxidative balance score in staging and mortality risk of cardiovascular-kidney-metabolic syndrome: insights from traditional and machine learning approaches
10.1016/j.redox.2025.103588 · 2025 · External reference
Insulin resistance assessed by estimated glucose disposal rate predicts cardiovascular disease in stages 0-3 of cardiovascular-kidney-metabolic syndrome: a UK biobank cohort study
10.1186/s12933-025-02860-z · 2025 · External reference
An epigenetic biomarker of aging for lifespan and healthspan
10.18632/aging.101414 · 2018 · External reference
A new measure of biological age based on clinical biomarkers predicts mortality and age-related diseases
2024 · External reference
Inflammation in cardiovascular-kidney-metabolic syndrome: key roles and underlying mechanisms-a comprehensive review
10.1007/s11010-025-05379-9 · 2025 · External reference
Role of residual inflammation as a risk factor across cardiovascular-kidney-metabolic (CKM) syndrome: unpacking the burden in people with type 2 diabetes
10.1007/s13300-025-01743-6 · 2025 · External reference
Antioxidant effects of SGLT2 inhibitors on cardiovascular-kidney-metabolic (CKM) syndrome
10.3390/antiox14060701 · 2025 · External reference
Depression severity as a predictor of cardiovascular-kidney-metabolic syndrome progression and mortality: results from two nationally representative cohort studies
10.1016/j.jad.2025.119606 · 2025 · External reference
Association of cardiovascular-kidney-metabolic syndrome with depression and all-cause mortality: a population-based observational study
10.3389/fnut.2025.1620008 · 2025 · External reference
Association between depressive symptoms and mortality in patients with cardiovascular-kidney-metabolic syndrome: the mediating role of inflammatory biomarkers
10.1016/j.jad.2025.119429 · 2025 · External reference
Role of depressive symptoms in accelerating cardiovascular diseases progression in cardiovascular-kidney-metabolic syndrome stages 0-3: a nationwide prospective cohort study
10.1016/j.genhosppsych.2025.07.013 · 2025 · External reference
Depression and mortality in population with cardiovascular-kidney-metabolic syndrome
10.1016/j.jad.2025.119773 · 2025 · External reference
Sex-specific associations between depression and cardiovascular-kidney-metabolic syndrome progression: a national cohort study
2026 · External reference
National health and nutrition examination survey: analytic guidelines, 1999-2010
2013 · External reference
Association of metabolic syndrome and sarcopenia with all-cause and cardiovascular mortality: a prospective cohort study based on the NHANES
10.3389/fendo.2024.1346669 · 2024 · External reference
Challenges and lessons learned in generating and interpreting NHANES nutritional biomarker data
10.3945/an.116.014076 · 2017 · External reference
Analyzing health surveys for cancer-related objectives
10.1093/jnci/91.12.1005 · 1999 · External reference
Quality control in planning and operating the laboratory component for the Third National Health and Nutrition Examination Survey
10.1093/jn/120.suppl_11.1451 · 1990 · External reference
Regression shrinkage and selection via the lasso
10.1111/j.2517-6161.1996.tb02080.x · 1996 · External reference
Regularization and variable selection via the elastic net
10.1111/j.1467-9868.2005.00503.x · 2005 · External reference
Allowing for mandatory covariates in boosting estimation of sparse high-dimensional survival models
10.1186/1471-2105-9-14 · 2008 · External reference
Random survival forests
10.1214/08-aoas169 · 2008 · External reference
Greedy function approximation: a gradient boosting machine
10.1214/aos/1013203451 · 2001 · External reference
A unified approach to interpreting model predictions.
2017 · External reference
2. Classification and diagnosis of diabetes: standards of medical care in diabetes-2021
2021 · External reference
2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol
2019 · External reference
A new equation to estimate glomerular filtration rate
10.7326/0003-4819-150-9-200905050-00006 · 2009 · External reference
The PHQ-9: validity of a brief depression severity measure
10.1046/j.1525-1497.2001.016009606.x · 2001 · External reference
Prognosis of non-albuminuric patients with the cardiovascular-kidney-metabolic syndrome
2025 · External reference
Cardiovascular-kidney-metabolic (CKM) syndrome is associated with increased mortality in individuals with metabolic dysfunction-associated steatotic liver disease (MASLD)
10.1038/s43856-025-01195-w · 2025 · External reference
Triglyceride-glucose-related indices and risk of cardiovascular disease and mortality in individuals with cardiovascular-kidney-metabolic (CKM) syndrome stages 0-3: a prospective cohort study of 282,920 participants in the UK Biobank
10.1186/s12933-025-02842-1 · 2025 · External reference
Association between atherogenic index of plasma with all-cause and cardiovascular mortality in individuals with Cardiovascular-Kidney-Metabolic syndrome
10.1186/s12933-025-02742-4 · 2025 · External reference
Association between remnant cholesterol and the risk of cardiovascular-kidney-metabolic syndrome progression: insights from the China health and retirement longitudinal study
10.1093/eurjpc/zwaf248 · 2025 · External reference
Cardiovascular-kidney-metabolic syndrome modifies smoking-related risk for cardiovascular diseases: findings from an observational cohort study in UK Biobank
10.1186/s12889-025-22865-3 · 2025 · External reference
Association of novel triglyceride-glucose-related indices with incident stroke in early-stage cardiovascular-kidney-metabolic syndrome
10.1186/s12933-025-02854-x · 2025 · External reference
Metabolomic profiling reveals interindividual metabolic variability and its association with cardiovascular-kidney-metabolic syndrome risk
10.1186/s12933-025-02881-8 · 2025 · External reference
Data-driven cluster analysis identifies distinct types of cardiovascular-kidney-metabolic syndrome
2025 · External reference
Association between triglyceride-glucose index and related indicators with heart failure-related mortality in individuals with early-stage cardiovascular-kidney-metabolic syndrome
10.1186/s12933-026-03149-5 · 2026 · External reference
Prevalence and long-term outcomes of NAFLD and cardiovascular-kidney-metabolic health in the United States
10.1016/j.ajpc.2025.101049 · 2025 · External reference
Prevalence and mortality of cardiovascular-kidney-metabolic syndrome in China: a nationwide population-based study
10.1016/j.jacasi.2025.04.007 · 2025 · External reference
Exercise in CKM syndrome progression: a stage-specific approach to cardiovascular, metabolic, and renal health
10.1186/s12933-025-03029-4 · 2025 · External reference
Association between the life’s essential 8 health behaviors and prognosis in patients with advanced cardiovascular-kidney-metabolic syndrome
2025 · External reference
Cardiovascular-kidney-metabolic (CKM) syndrome and the clinical laboratory
10.1177/00045632261420660 · 2026 · External reference
Large-scale proteomics-based risk score for the prediction of incident cardio-kidney-metabolic disease risk
10.1161/circgen.124.005125 · 2025 · External reference
Methodological considerations in CKM risk stratification: age validation of PREVENT equations
2025 · External reference
A simple score, CKM2S2-BAG, to predict cardiovascular risk with cardiovascular-kidney-metabolic health metrics
10.1016/j.isci.2025.112780 · 2025 · External reference
Cardio-kidney-metabolic (CKM) framework: a nephrologist’s perspective
2025 · External reference
Adipokines and vascular modulators in CKM: emerging biomarkers as diagnostic and therapeutic targets
10.3390/ijms262211083 · 2025 · External reference
SDOH, healthy lifestyle, and life expectancy in adults with CKM syndrome: two cohort studies
10.1016/j.pcad.2025.11.012 · 2026 · External reference
Social determinants of health (SDOH) associated with the risk of all-cause mortality and life expectancy in US adults with cardiovascular-kidney-metabolic syndrome: a NHANES 2001-2018 cohort study
10.1186/s12872-025-04812-7 · 2025 · External reference
Cardiovascular-kidney-metabolic syndrome and all-cause and cardiovascular mortality: a retrospective cohort study
2025 · External reference
Contemporary and emerging therapeutics in cardiovascular-kidney-metabolic (CKM) syndrome: in memory of Professor Akira Endo
10.3390/biomedicines13092192 · 2025 · External reference
Association between body roundness index and advanced cardiovascular-kidney-metabolic syndrome
10.3389/fnut.2025.1623766 · 2025 · External reference
Impact of DNA-methylation age acceleration on long-term mortality among US adults with cardiovascular-kidney-metabolic syndrome
2025 · External reference
The proteogenomic landscape of the human kidney and implications for cardio-kidney-metabolic health
10.1038/s41591-025-03872-8 · 2025 · External reference
MASLD in the CKM health framework: what does it add to the table?
2025 · External reference
