Research graph
References from Immunological characterization of a VIR protein family member (VIR-14) in Plasmodium vivax-infected subjects from different epidemiological regions in Africa and South America. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
External reference
Panorama epidemiológico da malária em 2021: buscando o caminho para a eliminação da malária no Brasil.;
2022 · External reference
Severe Plasmodium vivax malaria exhibits marked inflammatory imbalance.
10.1186/1475-2875-9-13 · 2010 · External reference
Global Epidemiology of Plasmodium vivax
10.4269/ajtmh.16-0141 · 2016 · External reference
Malaria in Brazil, Colombia, Peru and Venezuela: current challenges in malaria control and elimination.
10.1186/s12936-017-1925-6 · 2017 · External reference
Severe vivax malaria: a systematic review and meta-analysis of clinical studies since 1900.
10.1186/1475-2875-13-481 · 2014 · External reference
Epidemiology, drug resistance, and pathophysiology of.
10.4103/0972-9062.234620 · 2018 · External reference
The transcriptome of Plasmodium vivax reveals divergence and diversity of transcriptional regulation in malaria parasites
10.1073/pnas.0807404105 · 2008 · External reference
Plasmodium vivax in the Era of the Shrinking P. falciparum Map
10.1016/j.pt.2020.03.009 · 2020 · External reference
Immune mechanisms in malaria: new insights in vaccine development
10.1038/nm.3083 · 2013 · External reference
The Biology of.
2017 · External reference
Malaria
10.1038/nrdp.2017.50 · 2017 · External reference
Epigenetic Regulation of Virulence Gene Expression in Parasitic Protozoa.
10.1016/j.chom.2016.04.020 · 2016 · External reference
Diversity of vir genes in Plasmodium vivax from endemic regions in the Republic of Korea: an initial evaluation
10.3347/kjp.2017.55.2.149 · 2017 · External reference
On the cytoadhesion of Plasmodium vivax-infected erythrocytes
10.1086/654815 · 2010 · External reference
Plasmodium vivax VIR Proteins Are Targets of Naturally-Acquired Antibody and T Cell Immune Responses to Malaria in Pregnant Women.
10.1371/journal.pntd.0005009 · 2016 · External reference
Proteomic Analysis of Urine from Patients with
2022 · External reference
Structural and Immunological Characterization of Recombinant 6-Cysteine Domains of the Plasmodium falciparum Sexual Stage Protein Pfs230
10.1074/jbc.m116.732305 · 2016 · External reference
Structure of the Plasmodium falciparum circumsporozoite protein, a leading malaria vaccine candidate
10.1074/jbc.m109.013706 · 2009 · External reference
Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP
10.1038/s41564-019-0461-2 · 2019 · External reference
Red blood cell invasion by Plasmodium vivax: structural basis for DBP engagement of DARC
10.1371/journal.ppat.1003869 · 2014 · External reference
Naturally Acquired Antibody Response to Malaria Transmission Blocking Vaccine Candidate Pvs230 Domain 1.
10.3389/fimmu.2019.02295 · 2019 · External reference
Cytofkit: A Bioconductor Package for an Integrated Mass Cytometry Data Analysis Pipeline.
10.1371/journal.pcbi.1005112 · 2016 · External reference
A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes.
10.1038/s41467-021-21955-1 · 2021 · External reference
Sex-biased parasitism in vector-borne disease: Vector preference?
10.1371/journal.pone.0216360 · 2019 · External reference
Differential Patterns of IgG Subclass Responses to.
10.3389/fimmu.2019.00439 · 2019 · External reference
T cell-mediated immunity to malaria
10.1038/s41577-019-0158-z · 2019 · External reference
The Impact of Established Immunoregulatory Networks on Vaccine Efficacy and the Development of Immunity to Malaria
10.4049/jimmunol.1600619 · 2016 · External reference
Recent Insights into CD4
10.4049/jimmunol.1701316 · 2018 · External reference
Natural Killer Cells: Development, Maturation, and Clinical Utilization.
2018 · External reference
Unresolved reference
2018 · External reference
Progress towards the development of a P. vivax vaccine
2021 · External reference
Plasmodium vivax vaccine research—we’ve only just begun
10.1016/j.ijpara.2016.09.006 · 2017 · External reference
Urine-Based Antigen (Protein) Detection Test for the Diagnosis of Visceral Leishmaniasis.
10.3390/microorganisms8111676 · 2020 · External reference
Comparative genomics of the neglected human malaria parasite Plasmodium vivax
10.1038/nature07327 · 2008 · External reference
Unresolved reference
2021 · External reference
Malaria in Cambodia: A Retrospective Analysis of a Changing Epidemiology 2006–2019
10.3390/ijerph18041960 · 2021 · External reference
Age, exposure and immunity
10.7554/elife.40150 · 2018 · External reference
Evaluation of the acquired immune responses to Plasmodium vivax VIR variant antigens in individuals living in malaria-endemic areas of Brazil.
10.1186/1475-2875-5-83 · 2006 · External reference
IgM in human immunity to
10.1126/sciadv.aax4489 · 2019 · External reference
Acquired antibody responses against Plasmodium vivax infection vary with host genotype for duffy antigen receptor for chemokines (DARC).
10.1371/journal.pone.0011437 · 2010 · External reference
Acquisition and decay of IgM and IgG responses to merozoite antigens after Plasmodium falciparum malaria in Ghanaian children.
10.1371/journal.pone.0243943 · 2020 · External reference
Somatically Hypermutated Plasmodium-Specific IgM(+) Memory B Cells Are Rapid, Plastic, Early Responders upon Malaria Rechallenge.
10.1016/j.immuni.2016.06.014 · 2016 · External reference
IgM in human immunity to Plasmodium falciparum malaria
10.1126/sciadv.aax4489 · 2019 · External reference
Targets of complement-fixing antibodies in protective immunity against malaria in children
10.1038/s41467-019-08528-z · 2019 · External reference
Association between protection against clinical malaria and antibodies to merozoite surface antigens in an area of hyperendemicity in Myanmar: complementarity between responses to merozoite surface protein 3 and the 220-kilodalton glutamate-rich protein
10.1128/iai.72.1.247-252.2004 · 2004 · External reference
Malaria: What’s New in the Management of Malaria?
10.1016/j.idc.2018.10.002 · 2019 · External reference
Plasmodium vivax Duffy Binding Protein-Based Vaccine: a Distant Dream.
2022 · External reference
What Is Known about the Immune Response Induced by.
10.3389/fimmu.2017.00126 · 2017 · External reference
Malaria vaccines since 2000: progress, priorities, products.
10.1038/s41541-020-0196-3 · 2020 · External reference
Pregnancy and malaria exposure are associated with changes in the B cell pool and in plasma eotaxin levels
10.4049/jimmunol.1401037 · 2014 · External reference
Malaria-associated atypical memory B cells exhibit markedly reduced B cell receptor signaling and effector function
10.7554/elife.07218 · 2015 · External reference
Vivax infection alters peripheral B-cell profile and induces persistent serum IgM
10.1111/pim.12580 · 2018 · External reference
Shared transcriptional profiles of atypical B cells suggest common drivers of expansion and function in malaria, HIV, and autoimmunity
10.1126/sciadv.abg8384 · 2021 · External reference
Chronic Exposure to Malaria Is Associated with Inhibitory and Activation Markers on Atypical Memory B Cells and Marginal Zone-Like B Cells.
10.3389/fimmu.2017.00966 · 2017 · External reference
Potential functions of atypical memory B cells in Plasmodium-exposed individuals
10.1016/j.ijpara.2020.08.003 · 2020 · External reference
To B or Not to B: Understanding B Cell Responses in the Development of Malaria Infection.
10.3389/fimmu.2018.02961 · 2018 · External reference
B cell profiling in malaria reveals expansion and remodelling of CD11c+ B cell subsets.
2019 · External reference
Atypical B cells are part of an alternative lineage of B cells that participates in responses to vaccination and infection in humans
10.1016/j.celrep.2020.108684 · 2021 · External reference
B-cell activity in children with malaria.
10.1186/1475-2875-11-66 · 2012 · External reference
CD4+ T cells apoptosis in Plasmodium vivax infection is mediated by activation of both intrinsic and extrinsic pathways
10.1186/1475-2875-14-5 · 2015 · External reference
Exhausted CD4.
2020 · External reference
T cell control of malaria pathogenesis
10.1016/j.coi.2012.05.003 · 2012 · External reference
Phenotypic profiling of CD8(+) T cells during Plasmodium vivax blood-stage infection.
10.1186/s12879-015-0762-x · 2015 · External reference
Differentiation of human CD8(+) T cells from a memory to memory/effector phenotype.
10.4049/jimmunol.168.11.5538 · 2002 · External reference
CD27 is required for generation and long-term maintenance of T cell immunity
10.1038/80877 · 2000 · External reference
Blood-stage Plasmodium vivax antibody dynamics in a low transmission setting: A nine year follow-up study in the Amazon region.
10.1371/journal.pone.0207244 · 2018 · External reference
Duration of naturally acquired antibody responses to blood-stage Plasmodium falciparum is age dependent and antigen specific
10.1128/iai.01333-07 · 2008 · External reference
Naturally acquired antibody responses to more than 300 Plasmodium vivax proteins in three geographic regions
10.1371/journal.pntd.0005888 · 2017 · External reference
Apical membrane protein 1-specific antibody profile and temporal changes in peripheral blood B-cell populations in Plasmodium vivax malaria
10.1111/pim.12662 · 2019 · External reference
High-dimensional mass cytometry identifies T cell and B cell signatures predicting reduced risk of Plasmodium vivax malaria
10.1172/jci.insight.148086 · 2021 · External reference
Experimental malaria infection triggers early expansion of natural killer cells
10.1128/iai.00640-08 · 2008 · External reference
Activatory Receptor NKp30 Predicts NK Cell Activation During Controlled Human Malaria Infection.
10.3389/fimmu.2019.02864 · 2019 · External reference
PD-1 Expression on NK Cells in Malaria-Exposed Individuals Is Associated with Diminished Natural Cytotoxicity and Enhanced Antibody-Dependent Cellular Cytotoxicity
10.1128/iai.00711-19 · 2020 · External reference
Heterogeneous human NK cell responses to Plasmodium falciparum-infected erythrocytes
10.4049/jimmunol.175.11.7466 · 2005 · External reference
NK Cells: Uncertain Allies against Malaria.
2017 · External reference
Plasmodium falciparum-specific IgM B cells dominate in children, expand with malaria, and produce functional IgM
2021 · External reference
Induction and Kinetics of Complement-Fixing Antibodies Against Plasmodium vivax Merozoite Surface Protein 3α and Relationship With Immunoglobulin G Subclasses and Immunoglobulin M
10.1093/infdis/jiz407 · 2019 · External reference
Immunoglobulin somatic hypermutation
10.1146/annurev.genet.41.110306.130340 · 2007 · External reference
