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References from Intestinal inflammation induced by heat-labile toxin-producing enterotoxigenic E: Coli infection and impact on immune responses in an experimental human challenge model. Local targets link to admitted publications; unresolved targets remain external evidence.
Epidemiology of enterotoxigenic Escherichia coli and impact on the growth of children in the first two years of life in Lima, Peru
10.3389/fpubh.2024.1332319 · 2024 · External reference
Morbidity and mortality due to shigella and enterotoxigenic Escherichia coli diarrhoea: the Global Burden of Disease Study 1990-2016
10.1016/s1473-3099(18)30475-4 · 2018 · External reference
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010
2012 · External reference
Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010
10.1016/s0140-6736(12)61689-4 · 2012 · External reference
Epidemiology of Enterotoxigenic Escherichia coli among Children and Adults Seeking Care at Hospitals in Two Geographically Distinct Rural Areas in Bangladesh
10.3390/microorganisms12020359 · 2024 · External reference
A snap-shot of a diarrheal epidemic in Dhaka due to enterotoxigenic Escherichia coli and Vibrio cholerae O1 in 2022
10.3389/fpubh.2023.1132927 · 2023 · External reference
Vaccine value profile for enterotoxigenic Escherichia coli (ETEC)
10.1016/j.vaccine.2023.02.011 · 2023 · External reference
Enterotoxigenic Escherichia coli (ETEC) vaccines: Priority activities to enable product development, licensure, and global access
10.1016/j.vaccine.2021.04.018 · 2021 · External reference
Childhood malnutrition: toward an understanding of infections, inflammation, and antimicrobials
10.1177/15648265140352s110 · 2014 · External reference
Effects of Shigella-, Campylobacter- and ETEC-associated diarrhea on childhood growth
10.1097/inf.0000000000000351 · 2014 · External reference
Malnutrition as an enteric infectious disease with long-term effects on child development
10.1111/j.1753-4887.2008.00082.x · 2008 · External reference
Environmental enteric dysfunction and growth failure/stunting in global child health
10.1542/peds.2016-0641 · 2016 · External reference
Environmental enteric dysfunction: a review of potential mechanisms, consequences and management strategies
10.1186/s12916-019-1417-3 · 2019 · External reference
Injury and mechanism of recombinant E. coli expressing STa on piglets colon
10.1292/jvms.17-0528 · 2018 · External reference
Enterotoxigenic Escherichia coli Interferes FATP4-Dependent Long-Chain Fatty Acid Uptake of Intestinal Epithelial Enterocytes via Phosphorylation of ERK1/2-PPARγ Pathway
10.3389/fphys.2019.00798 · 2019 · External reference
I-FABP, Pig-MAP and TNF-α as biomarkers for monitoring gut-wall integrity in front of Salmonella Typhimurium and ETEC K88 infection in a weaned piglet model
10.1016/j.rvsc.2019.05.004 · 2019 · External reference
Changes in gut microbial populations, intestinal morphology, expression of tight junction proteins, and cytokine production between two pig breeds after challenge with Escherichia coli K88: a comparative study
10.2527/jas.2013-6528 · 2013 · External reference
Early weaning stress in pigs impairs innate mucosal immune responses to enterotoxigenic E. coli challenge and exacerbates intestinal injury and clinical disease
10.1371/journal.pone.0059838 · 2013 · External reference
Role of heat-stable enterotoxins in the induction of early immune responses in piglets after infection with enterotoxigenic Escherichia coli
10.1371/journal.pone.0041041 · 2012 · External reference
F4+ ETEC infection and oral immunization with F4 fimbriae elicits an IL-17-dominated immune response
10.1186/s13567-015-0264-2 · 2015 · External reference
Bacillus coagulans prevents the decline in average daily feed intake in young piglets infected with enterotoxigenic Escherichia coli K88 by reducing intestinal injury and regulating the gut microbiota
10.3389/fcimb.2023.1284166 · 2023 · External reference
Berberine alleviates ETEC-induced intestinal inflammation and oxidative stress damage by optimizing intestinal microbial composition in a weaned piglet model
10.3389/fimmu.2024.1460127 · 2024 · External reference
Modeling enteropathy or diarrhea with the top bacterial and protozoal pathogens: differential determinants of outcomes
10.1021/acsinfecdis.0c00831 · 2021 · External reference
Enteric Infections in Young Children are Associated with Environmental Enteropathy and Impaired Growth
10.1111/tmi.13002 · 2018 · External reference
Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study
10.1016/s0140-6736(13)60844-2 · 2013 · External reference
Intestinal and systemic inflammation induced by symptomatic and asymptomatic enterotoxigenic E. coli infection and impact on intestinal colonization and ETEC specific immune responses in an experimental human challenge model
10.1080/19490976.2021.1891852 · 2021 · External reference
Inflammation, the kynurenines, and mucosal injury during human experimental enterotoxigenic Escherichia coli infection
10.1007/s00430-024-00786-z · 2024 · External reference
Transcutaneous immunization with the heat-labile toxin (LT) of enterotoxigenic Escherichia coli (ETEC): protective efficacy in a double-blind, placebo-controlled challenge study
10.1016/j.vaccine.2007.01.043 · 2007 · External reference
Enterotoxigenic Escherichia coli heat-labile toxin drives enteropathic changes in small intestinal epithelia
10.1038/s41467-022-34687-7 · 2022 · External reference
CEACAMs serve as toxin-stimulated receptors for enterotoxigenic Escherichia coli
10.1073/pnas.2012480117 · 2020 · External reference
Toxin-mediated effects on the innate mucosal defenses: implications for enteric vaccines
10.1128/iai.00712-09 · 2009 · External reference
Heat-labile enterotoxin of Escherichia coli promotes intestinal colonization of Salmonella enterica
10.1016/j.cimid.2015.09.002 · 2015 · External reference
Importance of heat-labile enterotoxin in colonization of the adult mouse small intestine by human enterotoxigenic Escherichia coli strains
10.1128/iai.74.2.869-875.2006 · 2006 · External reference
Role of virulence factors on host inflammatory response induced by diarrheagenic Escherichia coli pathotypes
10.2217/fmb.15.17 · 2015 · External reference
Heat-Labile Enterotoxin Decreases Macrophage Phagocytosis of Enterotoxigenic Escherichia coli
10.3390/microorganisms11082121 · 2023 · External reference
Enterotoxigenic Escherichia coli heat labile enterotoxin affects neutrophil effector functions via cAMP/PKA/ERK signaling
10.1080/19490976.2024.2399215 · 2024 · External reference
Validation of a Human Challenge Model Using an LT-Expressing Enterotoxigenic E. coli Strain (LSN03-016011) and Characterization of Potential Amelioration of Disease by an Investigational Oral Vaccine Candidate (VLA1701)
10.3390/microorganisms12040727 · 2024 · External reference
Characterization of Mucosal Immune Responses to Enterotoxigenic Escherichia coli Vaccine Antigens in a Human Challenge Model: Response Profiles after Primary Infection and Homologous Rechallenge with Strain H10407
10.1128/cvi.00617-15 · 2015 · External reference
Impact of lower challenge doses of enterotoxigenic Escherichia coli on clinical outcome, intestinal colonization and immune responses in adult volunteers
10.1371/journal.pntd.0006442 · 2018 · External reference
Human Experimental Challenge With Enterotoxigenic Escherichia coli Elicits Immune Responses to Canonical and Novel Antigens Relevant to Vaccine Development
10.1093/infdis/jiy312 · 2018 · External reference
An Evidenced-Based Scale of Disease Severity following Human Challenge with Enteroxigenic Escherichia coli
10.1371/journal.pone.0149358 · 2016 · External reference
Evaluation of the Safety, Tolerability, and Immunogenicity of an Oral, Inactivated Whole-Cell Shigella flexneri 2a Vaccine in Healthy Adult Subjects
10.1128/cvi.00608-15 · 2016 · External reference
Refinement of a human challenge model for evaluation of enterotoxigenic Escherichia coli vaccines
10.1128/cvi.05194-11 · 2011 · External reference
Unresolved reference
External reference
User’s guide to correlation coefficients
10.1016/j.tjem.2018.08.001 · 2018 · External reference
Myeloperoxidase: its role for host defense, inflammation, and neutrophil function
10.1016/j.abb.2018.01.004 · 2018 · External reference
The MAL-ED study: a multinational and multidisciplinary approach to understand the relationship between enteric pathogens, malnutrition, gut physiology, physical growth, cognitive development, and immune responses in infants and children up to 2 years of age in resource-poor environments
2014 · External reference
The Controlled Human Infection Model for Enterotoxigenic Escherichia coli
2024 · External reference
The Inflammatory Response to Enterotoxigenic E. coli and Probiotic E. faecium in a Coculture Model of Porcine Intestinal Epithelial and Dendritic Cells
10.1155/2018/9368295 · 2018 · External reference
An J. Cytokines, Inflammation, and Pain.
10.1097/aia.0b013e318034194e · 2007 · External reference
Biomarkers of Environmental Enteropathy are Positively Associated with Immune Responses to an Oral Cholera Vaccine in Bangladeshi Children
10.1371/journal.pntd.0005039 · 2016 · External reference
A synergistic relationship between TNF-alpha, IL-1 beta, and TGF-beta 1 on IL-6 secretion by the IEC-6 intestinal epithelial cell line
1995 · External reference
Escherichia coli heat-labile enterotoxin promotes protective Th17 responses against infection by driving innate IL-1 and IL-23 production
10.4049/jimmunol.1003789 · 2011 · External reference
Options for inactivation, adjuvant, and route of topical administration of a killed, unencapsulated pneumococcal whole-cell vaccine
10.1128/cvi.00036-10 · 2010 · External reference
Th17 cells at the crossroads of innate and adaptive immunity against infectious diseases at the mucosa
10.1038/mi.2009.100 · 2009 · External reference
Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis
10.1084/jem.20081463 · 2009 · External reference
The adjuvant double mutant Escherichia coli heat labile toxin enhances IL-17A production in human T cells specific for bacterial vaccine antigens
10.1371/journal.pone.0051718 · 2012 · External reference
T helper cell responses in adult diarrheal patients following natural infection with enterotoxigenic Escherichia coli are primarily of the Th17 type
10.3389/fimmu.2023.1220130 · 2023 · External reference
Chronic inflammation in the etiology of disease across the life span
10.1038/s41591-019-0675-0 · 2019 · External reference
Assessment of the duration of protection in Campylobacter jejuni experimental infection in humans
10.1128/iai.01021-09 · 2010 · External reference
Comparisons between myeloperoxidase, lactoferrin, calprotectin and lipocalin-2, as fecal biomarkers of intestinal inflammation in malnourished children
10.15761/jts.1000130 · 2016 · External reference
