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References from Engineered Nanobodies for early and accurate diagnosis of dengue virus infection. Local targets link to admitted publications; unresolved targets remain external evidence.
Minireview: Epidemiological impact of arboviral diseases in Latin American countries, arbovirus-vector interactions and control strategies
10.1093/femspd/ftab043 · 2021 · External reference
The association between dengue case and climate: A systematic review and meta-analysis
10.1016/j.onehlt.2022.100452 · 2022 · External reference
Facing the escalating burden of dengue: Challenges and perspectives
10.1371/journal.pgph.0002598 · 2023 · External reference
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Dengue, chikungunya, and Zika virus infections in Latin America and the Caribbean: a systematic review
2023 · External reference
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Dengue emergence in the temperate Argentinian province of Santa Fe, 2009-2020
10.1038/s41597-021-00914-x · 2021 · External reference
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Dynamics and epidemiological characterization of the dengue outbreak in Argentina 2016: the case of the Province of Buenos Aires
10.4067/s0716-10182019000100016 · 2019 · External reference
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Dengue virus infection - a review of pathogenesis, vaccines, diagnosis and therapy
10.1016/j.virusres.2022.199018 · 2023 · External reference
Secretory pathways and multiple functions of nonstructural protein 1 in flavivirus infection
10.3389/fimmu.2023.1205002 · 2023 · External reference
Sensitivity and Cross-Reactivity Analysis of Serotype-Specific Anti-NS1 Serological Assays for Dengue Virus Using Optical Modulation Biosensing
10.3390/bios15070453 · 2025 · External reference
CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever
10.1038/s41467-022-34415-1 · 2022 · External reference
Structural biology of flavivirus NS1 protein and its antibody complexes
10.1016/j.antiviral.2024.105915 · 2024 · External reference
Dengue: A review of laboratory diagnostics in the vaccine age
10.1099/jmm.0.001833 · 2024 · External reference
The Role of NS1 Protein in the Diagnosis of Flavivirus Infections
10.3390/v15020572 · 2023 · External reference
Kinetics of NS1 and anti-NS1 IgG following dengue infection reveals likely early formation of immune complexes in secondary infected patients
10.1038/s41598-025-91099-5 · 2025 · External reference
Determination of viremia and concentration of circulating nonstructural protein 1 in patients infected with dengue virus in Mexico
10.4269/ajtmh.12-0023 · 2013 · External reference
High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever
10.1086/343813 · 2002 · External reference
Association of dengue virus non-structural-1 protein with disease severity: a brief review
10.1093/trstmh/trac087 · 2022 · External reference
Effects of a five-year citywide intervention program to control Aedes aegypti and prevent dengue outbreaks in northern Argentina
10.1371/journal.pntd.0000427 · 2009 · External reference
Ecobiosocial community intervention for improved Aedes aegypti control using water container covers to prevent dengue: lessons learned from Girardot Colombia
10.1007/s10393-014-0953-8 · 2014 · External reference
Tracing down the Updates on Dengue Virus-Molecular Biology, Antivirals, and Vaccine Strategies
10.3390/vaccines11081328 · 2023 · External reference
Dengue Vaccines: An Update
10.1007/s40259-022-00531-z · 2022 · External reference
Current Trends and Limitations in Dengue Antiviral Research
10.3390/tropicalmed6040180 · 2021 · External reference
Molecular Mechanisms of Antiviral Agents against Dengue Virus
10.3390/v15030705 · 2023 · External reference
Clinical Features of COVID-19, Dengue, and Influenza among Adults Presenting to Emergency Departments and Urgent Care Clinics-Puerto Rico, 2012-2021
10.4269/ajtmh.22-0149 · 2022 · External reference
The Use of NS1 Rapid Diagnostic Test and qRT-PCR to Complement IgM ELISA for Improved Dengue Diagnosis from Single Specimen
10.1038/srep27663 · 2016 · External reference
The diagnostic sensitivity of dengue rapid test assays is significantly enhanced by using a combined antigen and antibody testing approach
2011 · External reference
Diagnostic approaches for dengue infection
10.1080/14737159.2023.2234815 · 2023 · External reference
Evaluation of diagnostic tests: dengue
2010 · External reference
Innovations in dengue virus detection: An overview of conventional and electrochemical biosensor approaches
10.1002/bab.2553 · 2024 · External reference
Lateral flow immunoassay (LFIA) for dengue diagnosis: Recent progress and prospect
10.1016/j.talanta.2023.125268 · 2024 · External reference
Use of Graphene and Its Derivatives for the Detection of Dengue Virus
10.3390/bios13030349 · 2023 · External reference
Micro- and nanosystems for the detection of hemorrhagic fever viruses
10.1039/d3lc00482a · 2023 · External reference
Recent Developments in DNA-Nanotechnology-Powered Biosensors for Zika/Dengue Virus Molecular Diagnostics
10.3390/nano13020361 · 2023 · External reference
Peptide Biomarkers for the Diagnosis of Dengue Infection
10.3389/fimmu.2022.793882 · 2022 · External reference
Economic impact of dengue fever in Latin America and the Caribbean: a systematic review
10.26633/rpsp.2018.111 · 2018 · External reference
Naturally occurring antibodies devoid of light chains
10.1038/363446a0 · 1993 · External reference
30 years of nanobodies - an ongoing success story of small binders in biological research
10.1242/jcs.261395 · 2023 · External reference
Nanobodies: natural single-domain antibodies
10.1146/annurev-biochem-063011-092449 · 2013 · External reference
Nanobodies in the limelight: Multifunctional tools in the fight against viruses
10.1099/jgv.0.001731 · 2022 · External reference
Single-domain antibodies applied as antiviral immunotherapeutics
10.1016/j.jviromet.2023.114787 · 2023 · External reference
Epidemiological and clinical features of the 2016-2018 Zika virus outbreak in northern Argentina
10.1093/trstmh/trad013 · 2023 · External reference
Expression of recombinant dengue virus type 1 non-structural protein 1 in mammalian cells and preliminary assessment of its suitability to detect human IgG antibodies elicited by viral infection
10.1016/j.jim.2023.113503 · 2023 · External reference
A general protocol for the generation of Nanobodies for structural biology
10.1038/nprot.2014.039 · 2014 · External reference
A multispecies competitive nanobody-based ELISA for the detection of antibodies against hepatitis E virus
10.1038/s41598-023-41955-z · 2023 · External reference
MEGA11: Molecular Evolutionary Genetics Analysis Version 11
10.1093/molbev/msab120 · 2021 · External reference
Discovery of a polystyrene binding peptide isolated from phage display library and its application in peptide immobilization
10.1038/s41598-017-02891-x · 2017 · External reference
Characterization of polystyrene-binding peptides (PS-tags) for site-specific immobilization of proteins
10.1016/j.jbiosc.2009.11.005 · 2010 · External reference
RNA Binding and HEPN-Nuclease Activation Are Decoupled in CRISPR-Cas13a
10.1016/j.celrep.2018.06.105 · 2018 · External reference
Production of unnaturally linked chimeric proteins using a combination of sortase-catalyzed transpeptidation and click chemistry
10.1038/nprot.2013.103 · 2013 · External reference
A general strategy for the evolution of bond-forming enzymes using yeast display
10.1073/pnas.1101046108 · 2011 · External reference
Streamlined method for parallel identification of single domain antibodies to membrane receptors on whole cells
10.1016/j.bbagen.2015.03.009 · 2015 · External reference
Picomolar SARS-CoV-2 Neutralization Using Multi-Arm PEG Nanobody Constructs
10.3390/biom10121661 · 2020 · External reference
A Coefficient of Agreement for Nominal Scales
10.1177/001316446002000104 · 1960 · External reference
Dengue beyond the tropics: a time-series study comprising 2015-2016 versus 2019-2020 at a children’s hospital in the City of Buenos Aires
2022 · External reference
Prevalence of antibodies against dengue virus in the city of Buenos Aires: Results of a probabilistic population survey
10.1371/journal.pntd.0012886 · 2025 · External reference
Epidemiology of Dengue in Argentina during the 2010/11 to 2019/20 Seasons: A Contribution to the Burden of Disease
10.3390/tropicalmed9020045 · 2024 · External reference
Dengue, chikungunya and the mosquito vector at the Southern limit of distribution during the 2023 epidemic, Argentina
2024 · External reference
Recombinant expression of nanobodies and nanobody-derived immunoreagents
10.1016/j.pep.2020.105645 · 2020 · External reference
High yield purification of nanobodies from the periplasm of E. coli as fusions with the maltose binding protein
10.1016/j.pep.2013.07.001 · 2013 · External reference
Improving the yield of recalcitrant Nanobodies® by simple modifications to the standard protocol
10.1016/j.pep.2021.105906 · 2021 · External reference
A simple heat dissociation method increases significantly the ELISA detection sensitivity of the nonstructural-1 glycoprotein in patients infected with DENV type-4
10.1016/j.jviromet.2014.02.031 · 2014 · External reference
Improving dengue viral antigens detection in dengue patient serum specimens using a low pH glycine buffer treatment
10.1016/j.jmii.2015.05.008 · 2017 · External reference
Increased sensitivity of NS1 ELISA by heat dissociation in acute dengue 4 cases
10.1186/s12879-017-2306-z · 2017 · External reference
The Measurement of Observer Agreement for Categorical Data
10.2307/2529310 · 1977 · External reference
Discovery of nanobodies: a comprehensive review of their applications and potential over the past five years
10.1186/s12951-024-02900-y · 2024 · External reference
Cost and supply considerations for antibody therapeutics
10.1080/19420862.2025.2451789 · 2025 · External reference
Selection and Characterization of Anti-Dengue NS1 Single Domain Antibodies
2018 · External reference
Oriented Immobilization of Single-Domain Antibodies Using SpyTag/SpyCatcher Yields Improved Limits of Detection
10.1021/acs.analchem.9b02096 · 2019 · External reference
Secreted dengue virus nonstructural protein NS1 is an atypical barrel-shaped high-density lipoprotein
10.1073/pnas.1017338108 · 2011 · External reference
Use of a commercial enzyme immunoassay to monitor dengue virus replication in cultured cells
10.1186/1743-422x-5-51 · 2008 · External reference
Development of a quantitative NS1-capture enzyme-linked immunosorbent assay for early detection of yellow fever virus infection
10.1038/s41598-017-16231-6 · 2017 · External reference
Detection and sequencing of defective viral genomes in C6/36 cells persistently infected with dengue virus 2
10.1007/s00705-012-1525-2 · 2013 · External reference
The dengue virus non-structural protein 1 (NS1) is secreted efficiently from infected mosquito cells
10.1016/j.virol.2015.11.020 · 2016 · External reference
Single-Domain Antibodies Targeting Neuraminidase Protect against an H5N1 Influenza Virus Challenge
10.1128/jvi.03178-13 · 2014 · External reference
Anti-HIV-1 Nanobody-IgG1 Constructs With Improved Neutralization Potency and the Ability to Mediate Fc Effector Functions
10.3389/fimmu.2022.893648 · 2022 · External reference
Multivalent CXCR4-targeting nanobody formats differently affect affinity, receptor clustering, and antagonism
10.1016/j.bcp.2024.116457 · 2024 · External reference
A Novel Nanobody-Horseradish Peroxidase Fusion Based-Competitive ELISA to Rapidly Detect Avian Corona-Virus-Infectious Bronchitis Virus Antibody in Chicken Serum
10.3390/ijms23147589 · 2022 · External reference
HRP-conjugated-nanobody-based cELISA for rapid and sensitive clinical detection of ASFV antibodies
10.1007/s00253-022-11981-4 · 2022 · External reference
Secreted dengue virus NS1 from infection is predominantly dimeric and in complex with high-density lipoprotein
2024 · External reference
Flavivirus NS1 structures reveal surfaces for associations with membranes and the immune system
10.1126/science.1247749 · 2014 · External reference
Camelid VHH Antibodies that Neutralize Botulinum Neurotoxin Serotype E Intoxication or Protease Function
10.3390/toxins12100611 · 2020 · External reference
Secretion of Nonstructural Protein 1 of Dengue Virus from Infected Mosquito Cells: Facts and Speculations
10.1128/jvi.00275-18 · 2018 · External reference
Multivalent nanobody as capture antibody-based enzyme linked immunosorbent assay for detection of 3-phenoxybenzoic acid in urine
10.1016/j.ab.2021.114390 · 2021 · External reference
Development of Improved Double-Nanobody Sandwich ELISAs for Human Soluble Epoxide Hydrolase Detection in Peripheral Blood Mononuclear Cells of Diabetic Patients and the Prefrontal Cortex of Multiple Sclerosis Patients
10.1021/acs.analchem.0c01115 · 2020 · External reference
Development of a Nanobody-based lateral flow assay to detect active Trypanosoma congolense infections
10.1038/s41598-018-26732-7 · 2018 · External reference
Fenobody and RANbody-based sandwich enzyme-linked immunosorbent assay to detect Newcastle disease virus
10.1186/s12951-020-00598-2 · 2020 · External reference
Enhancing Nanobody Immunoassays through Ferritin Fusion: Construction of a Salmonella-Specific Fenobody for Improved Avidity and Sensitivity
10.1021/acs.jafc.4c03606 · 2024 · External reference
Iodoacetyl-functionalized pullulan: A supplemental enhancer for single-domain antibody-polyclonal antibody sandwich enzyme-linked immunosorbent assay for detection of survivin
10.1016/j.bmcl.2017.09.045 · 2017 · External reference
Multivalent nanobody–biotin amplified enzyme-linked immunosorbent assay for the environmental detection of 3-phenoxybenzoic acid
10.1039/d1ay01491a · 2021 · External reference
Development of Nanobodies against Mal de Río Cuarto virus major viroplasm protein P9-1 for diagnostic sandwich ELISA and immunodetection
10.1038/s41598-021-99275-z · 2021 · External reference
Development of a Highly Sensitive Enzyme-Linked Immunosorbent Assay for Mouse Soluble Epoxide Hydrolase Detection by Combining a Polyclonal Capture Antibody with a Nanobody Tracer
10.1021/acs.analchem.0c01511 · 2020 · External reference
Development of VHH antibodies against dengue virus type 2 NS1 and comparison with monoclonal antibodies for use in immunological diagnosis
10.1371/journal.pone.0095263 · 2014 · External reference
Generation of a Large Repertoire of Monoclonal Antibodies against Dengue Virus NS1 Antigen and the Development of a Novel NS1 Detection Enzyme-Linked Immunosorbent Assay
10.4049/jimmunol.2200251 · 2022 · External reference
Evaluation of a dengue NS1 antigen detection assay sensitivity and specificity for the diagnosis of acute dengue virus infection
10.1371/journal.pntd.0003193 · 2014 · External reference
Evaluation of an enzyme immunoassay for detection of dengue virus NS1 antigen in human serum
10.1128/cvi.00229-06 · 2006 · External reference
Evaluation of dengue NS1 antigen rapid tests and ELISA kits using clinical samples
2014 · External reference
Performance of commercial dengue NS1 ELISA and molecular analysis of NS1 gene of dengue viruses obtained during surveillance in Indonesia
10.1186/1471-2334-13-611 · 2013 · External reference
Dengue-4 false negative results by Panbio® Dengue Early ELISA assay in Brazil
10.1016/j.jcv.2013.10.021 · 2013 · External reference
Structural and immunological basis of cross-reactivity between dengue and Zika infections: Implications in serosurveillance in endemic regions
10.3389/fmicb.2023.1107496 · 2023 · External reference
A Highly Conserved Region Between Amino Acids 221 and 266 of Dengue Virus Non-Structural Protein 1 is a Major Epitope Region in Infected Patients
10.4269/ajtmh.13-0624 · 2014 · External reference
Low Sensitivity of NS1 Protein Tests Evidenced during a Dengue Type 2 Virus Outbreak in Santos, Brazil, in 2010
10.1128/cvi.00535-12 · 2012 · External reference
Detection of Immune-Complex-Dissociated Nonstructural-1 Antigen in Patients with Acute Dengue Virus Infections
10.1128/jcm.41.9.4154-4159.2003 · 2003 · External reference
ROTADIAL: The first nanobody-based immunoassay to detect Group A Rotavirus
10.1016/j.jviromet.2021.114279 · 2021 · External reference
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