Research graph
References from Global genomic and antimicrobial resistance profiling of Neisseria gonorrhoeae: Insights from whole genome sequencing and minimum inhibitory concentration analysis. Local targets link to admitted publications; unresolved targets remain external evidence.
Global trends of antimicrobial resistance rates in Neisseria gonorrhoeae: a systematic review and meta-analysis
10.3389/fphar.2024.1284665 · 2024 · External reference
World Health Organization Global Gonococcal Antimicrobial Surveillance Program (WHO GASP): review of new data and evidence to inform international collaborative actions and research efforts
10.1071/sh19023 · 2019 · External reference
Azithromycin resistance through interspecific acquisition of an epistasis-dependent efflux pump component and transcriptional regulator in Neisseria gonorrhoeae
10.1128/mbio.01419-18 · 2018 · External reference
WHO Global Antimicrobial Resistance Surveillance for Neisseria Gonorrhoeae 2017–18: A Retrospective Observational Study
10.1016/s2666-5247(21)00171-3 · 2021 · External reference
Expanding U.S. Laboratory Capacity for Neisseria gonorrhoeae Antimicrobial Susceptibility Testing and Whole-Genome Sequencing through the CDC’s Antibiotic Resistance Laboratory Network
10.1128/jcm.01461-19 · 2020 · External reference
Mechanistic basis for decreased antimicrobial susceptibility in a clinical isolate of Neisseria gonorrhoeae possessing a mosaic-like mtr efflux pump locus
10.1128/mbio.02281-18 · 2018 · External reference
Commensal Neisseria Are Shared Between Sexual Partners: Implications for Gonococcal and Meningococcal Antimicrobial Resistance
10.3390/pathogens9030228 · 2020 · External reference
Genetic resistance determinants, in vitro time-kill curve analysis and pharmacodynamic functions for the novel topoisomerase II inhibitor ETX0914 (AZD0914) in Neisseria gonorrhoeae
10.3389/fmicb.2015.01377 · 2015 · External reference
Genomic epidemiology and population structure of Neisseria gonorrhoeae from remote highly endemic Western Australian populations
10.1186/s12864-018-4557-5 · 2018 · External reference
A community-driven resource for genomic epidemiology and antimicrobial resistance prediction of Neisseria gonorrhoeae at Pathogenwatch
10.1186/s13073-021-00858-2 · 2021 · External reference
Neisseria gonorrhoeae clustering to reveal major European whole-genome-sequencing-based genogroups in association with antimicrobial resistance
2021 · External reference
The novel 2024 WHO Neisseria gonorrhoeae reference strains for global quality assurance of laboratory investigations and superseded WHO N. gonorrhoeae reference strains-phenotypic, genetic and reference genome characterization
10.1093/jac/dkae176 · 2024 · External reference
Gen2Epi: an automated whole-genome sequencing pipeline for linking full genomes to antimicrobial susceptibility and molecular epidemiological data in Neisseria gonorrhoeae
10.1186/s12864-019-5542-3 · 2019 · External reference
Genomic Diversity and Chromosomal Rearrangements in Neisseria gonorrhoeae and Neisseria meningitidis
10.3390/ijms232415644 · 2022 · External reference
Where does Neisseria acquire foreign DNA from: an examination of the source of genomic and pathogenic islands and the evolution of the Neisseria genus
10.1186/1471-2148-13-184 · 2013 · External reference
Equations To Predict Antimicrobial MICs in Neisseria gonorrhoeae Using Molecular Antimicrobial Resistance Determinants
10.1128/aac.02005-19 · 2020 · External reference
Antimicrobial Resistance Profiles of Human Commensal Neisseria Species
10.3390/antibiotics10050538 · 2021 · External reference
Effect of the environment on horizontal gene transfer between bacteria and archaea
10.7717/peerj.3865 · 2017 · External reference
Trends in prokaryotic evolution revealed by comparison of closely related bacterial and archaeal genomes
10.1128/jb.01237-08 · 2009 · External reference
A variable genetic island specific for Neisseria gonorrhoeae is involved in providing DNA for natural transformation and is found more often in disseminated infection isolates
10.1046/j.1365-2958.2001.02520.x · 2001 · External reference
Gonococcal lipooligosaccharide is a ligand for the asialoglycoprotein receptor on human sperm
10.1046/j.1365-2958.2000.01938.x · 2000 · External reference
Meningococcal quinolone resistance originated from several commensal Neisseria species
10.1128/aac.01494-19 · 2020 · External reference
Association of phylogenomic relatedness between Neisseria gonorrhoeae strains with antimicrobial resistance, Austria, 2016–2020
10.3201/eid2808.220071 · 2022 · External reference
Distinct Trajectories of Massive Recent Gene Gains and Losses in Populations of a Microbial Eukaryotic Pathogen
10.1093/molbev/msx208 · 2017 · External reference
Divergent genome evolution caused by regional variation in DNA gain and loss between human and mouse
10.1371/journal.pcbi.1006091 · 2018 · External reference
HMGA1-pseudogenes and cancer
10.18632/oncotarget.7427 · 2016 · External reference
Microbial species delineation using whole genome sequences
10.1093/nar/gkv657 · 2015 · External reference
The GENCODE Pseudogene Resource
2012 · External reference
Identification and analysis of unitary pseudogenes: historic and contemporary gene losses in humans and other primates
10.1186/gb-2010-11-3-r26 · 2010 · External reference
Neisseria gonorrhoeae Population Genomics: Use of the Gonococcal Core Genome to Improve Surveillance of Antimicrobial Resistance
10.1093/infdis/jiaa002 · 2020 · External reference
Mosaic structure of the penA gene in the oropharynx of men who have sex with men negative for gonorrhoea
10.1177/0956462419889265 · 2020 · External reference
The Gonococcal Genetic Island defines distinct sub-populations of Neisseria gonorrhoeae
2023 · External reference
Mobile genetic elements in Neisseria gonorrhoeae: movement for change
10.1093/femspd/ftx071 · 2017 · External reference
Emergence and evolution of mosaic penA-60 and penA-237 alleles in a Neisseria gonorrhoeae core genogroup that was historically susceptible to extended spectrum cephalosporins
10.3389/fmicb.2024.1401303 · 2024 · External reference
Emergence and evolution of antimicrobial resistance genes and mutations in Neisseria gonorrhoeae
10.1186/s13073-021-00860-8 · 2021 · External reference
Integrated chromosomal and plasmid sequence analyses reveal diverse modes of carbapenemase gene spread among Klebsiella pneumoniae
10.1073/pnas.2003407117 · 2020 · External reference
High-level cefixime- and ceftriaxone-resistant Neisseria gonorrhoeae in France: novel penA mosaic allele in a successful international clone causes treatment failure
10.1128/aac.05760-11 · 2012 · External reference
Cryo-Em Structures of a Gonococcal Multidrug Efflux Pump Illuminate a Mechanism of Drug Recognition and Resistance
2020 · External reference
Susceptibility of Neisseria gonorrhoeae to azithromycin and ceftriaxone in China: A retrospective study of national surveillance data from 2013 to 2016
2018 · External reference
The Prevalence of Antibiotic Tolerance in Neisseria gonorrhoeae Varies by Anatomical Site
10.3390/pathogens13070538 · 2024 · External reference
Suboptimal therapy and clinical management of gonorrhoea in an area with high-level antimicrobial resistance
10.1258/ijsa.2008.008286 · 2009 · External reference
Multicopy plasmids potentiate the evolution of antibiotic resistance in bacteria
10.1038/s41559-016-0010 · 2016 · External reference
Comparative genomic analysis of Chryseobacterium species: deep insights into plant-growth-promoting and halotolerant capacities
2023 · External reference
Molecular epidemiology of Neisseria gonorrhoeae isolates from Saskatchewan, Canada: utility of NG-MAST in predicting antimicrobial susceptibility regionally
10.1136/sextrans-2013-051229 · 2014 · External reference
Characterization of 2 Neisseria gonorrhoeae Strains With High-Level Azithromycin Resistance Isolated in 2015 and 2018 in Japan
10.1097/olq.0000000000001303 · 2021 · External reference
Whole-Genome Sequencing of Russian Neisseria Gonorrhoeae Isolates Related to ST 1407 Genogroup
10.32607/20758251-2018-10-3-68-76 · 2018 · External reference
Molecular characterisation of Neisseria gonorrhoeae associated with disseminated gonococcal infections in Queensland, Australia: a retrospective surveillance study
2022 · External reference
A null model for microbial diversification
10.1073/pnas.1619993114 · 2017 · External reference
A pharmacodynamic study of aminoglycosides against pathogenic E. coli through Monte Carlo simulation
10.3390/ph17010027 · 2023 · External reference
Comparative Analysis of the Incidence of Selected Sexually Transmitted Viral Infections in Poland in 2010-2015: A Retrospective Cohort Study
10.3390/jcm11123448 · 2022 · External reference
The Accuracy of Molecular Detection Targeting the Mutation C2611T for Detecting Moderate-Level Azithromycin Resistance in Neisseria gonorrhoeae: A Systematic Review and Meta-Analysis
10.3390/antibiotics10091027 · 2021 · External reference
Chlamydia, gonorrhoea, trichomoniasis and syphilis: global prevalence and incidence estimates, 2016
10.2471/blt.18.228486 · 2019 · External reference
Sexually Transmitted Neisseria Gonorrhoeae Infections—Update on Drug Treatment and Vaccine Development
10.3390/medicines8020011 · 2021 · External reference
Antimicrobial Susceptibility Testing Patterns of Neisseria gonorrhoeae from Patients Attending Sexually Transmitted Infections Clinics in Six Regions in Tanzania
10.3390/tropicalmed7060089 · 2022 · External reference
Variability in Azithromycin Susceptibility Results for Neisseria gonorrhoeae Obtained Using Gradient MIC Strip and Agar Dilution Techniques
10.1128/jcm.01353-19 · 2019 · External reference
Gonococcal Genetic Island in the Global Neisseria gonorrhoeae Population: A Model of Genetic Diversity and Association with Resistance to Antimicrobials
10.3390/microorganisms11061547 · 2023 · External reference
Antimicrobial resistance and heterogeneity of Neisseria gonorrhoeae isolated from patients attending sexually transmitted infection clinics in Lusaka, Zambia
10.1186/s12864-024-10155-y · 2024 · External reference
Molecular Characteristics and the Effect of Mutations in Different Sites of the rplD Gene Among Clinical Isolates of Azithromycin Resistance Neisseria gonorrhoeae in Eastern China
2023 · External reference
The Gonococcal Transcriptome during Infection of the Lower Genital Tract in Women
10.1371/journal.pone.0133982 · 2015 · External reference
Transcriptome analysis of Neisseria gonorrhoeae during natural infection reveals differential expression of antibiotic resistance determinants between men and women
10.1128/mspheredirect.00312-18 · 2018 · External reference
Neisseria gonorrhoeae Sequence Typing for Antimicrobial Resistance, a Novel Antimicrobial Resistance Multilocus Typing Scheme for Tracking Global Dissemination of N. gonorrhoeae Strains
10.1128/jcm.00100-17 · 2017 · External reference
Molecular epidemiology of drug-resistant Neisseria gonorrhoeae in Russia (Current Status, 2015)
10.1186/s12879-016-1688-7 · 2016 · External reference
In Vitro Susceptibility to Β-Lactam Antibiotics and Viability of Neisseria Gonorrhoeae Strains Producing Plasmid-Mediated Broad- and Extended-Spectrum Β-Lactamases
10.3389/fmicb.2022.896607 · 2022 · External reference
Differential contribution of PBP occupancy and efflux on the effectiveness of β-lactams at their target site in clinical isolates of Neisseria gonorrhoeae
10.1371/journal.ppat.1012783 · 2024 · External reference
10.47750/jptcp.2023.30.03.006
10.47750/jptcp.2023.30.03.006 · External reference
Antimicrobial Resistance And Molecular Characteristics Among Neisseria gonorrhoeae Clinical Isolates In A Chinese Tertiary Hospital
10.2147/idr.s221109 · 2019 · External reference
Detection of presumed genes encoding beta-lactamases by sequence based screening of metagenomes derived from Antarctic microbial mats
10.1007/s11783-019-1128-1 · 2019 · External reference
Penicillinase plasmid Australia type in Neisseria gonorrhoeae isolated in Poland
10.1007/s00203-021-02623-w · 2022 · External reference
Resistance of Neisseria gonorrhoeae isolates to beta-lactam antibiotics (benzylpenicillin and ceftriaxone) in Russia, 2015–2017
10.1371/journal.pone.0220339 · 2019 · External reference
Evidence of Recent Genomic Evolution in Gonococcal Strains With Decreased Susceptibility to Cephalosporins or Azithromycin in the United States, 2014-2016
10.1093/infdis/jiz079 · 2019 · External reference
Phenotypic and Genotypic Characterization of Macrolide-Lincosamide-Streptogramin Resistance in Staphylococcus aureus Isolates from Bovine and Human
10.2478/acve-2023-0008 · 2023 · External reference
Staphylococcus aureus: An unusual resistance mechanism?
2015 · External reference
Exploring the mobilome and resistome of Enterococcus faecium in a One Health context across two continents
2022 · External reference
Identification of knowledge gaps in whole-genome sequence analysis of multi-resistant thermotolerant Campylobacter spp
10.1186/s12864-024-10014-w · 2024 · External reference
Circular intermediate-mediated horizontal transfer of the chromosome-encoded cfr(c) gene in multi-drug resistant Campylobacter coli from swine sources
2023 · External reference
Characterization of Staphylococci and Streptococci Isolated from Milk of Bovides with Mastitis in Egypt
10.3390/pathogens9050381 · 2020 · External reference
Chromosomal Conjugative and Mobilizable Elements in Streptococcus suis: Major Actors in the Spreading of Antimicrobial Resistance and Bacteriocin Synthesis Genes
10.3390/pathogens9010022 · 2019 · External reference
Differences in distribution of MLS antibiotics resistance genes in clinical isolates of staphylococci belonging to species: S. epidermidis, S. hominis, S. haemolyticus, S. simulans and S. warneri
10.1186/s12866-019-1496-5 · 2019 · External reference
Characterization of Streptococcus pyogenes from animal clinical specimens, Spain
10.3201/eid2312.151146 · 2017 · External reference
ermA, ermC , tetM and tetK are essential for erythromycin and tetracycline resistance among methicillin-resistant Staphylococcus aureus strains isolated from a tertiary hospital in Malaysia
10.4103/0255-0857.96693 · 2012 · External reference
Antibiotics Resistance Genes Screening and Comparative Genomics Analysis of Commensal Escherichia coli Isolated from Poultry Farms between China and Sudan
10.1155/2018/5327450 · 2018 · External reference
Co-Occurrence of blaNDM-1 and blaOXA-48 Among Carbapenem Resistant Enterobacteriaceae Isolates Causing Bloodstream Infections in Alexandria, Egypt
10.21608/ejmm.2022.247169 · 2022 · External reference
Prevalence, Antimicrobial Resistance, and Molecular Description of Pseudomonas aeruginosa Isolated from Meat and Meat Products
10.1155/2022/9899338 · 2022 · External reference
Whole Genome Sequencing and Characteristics of Extended-Spectrum Beta-Lactamase Producing Escherichia Coli Isolated From Poultry Farms in Banaskantha, India
10.3389/fmicb.2022.996214 · 2022 · External reference
Emerging azithromycin-resistance among the Neisseria gonorrhoeae strains isolated in Hungary
10.1186/s12941-016-0166-9 · 2016 · External reference
Phylogeny and Antimicrobial Resistance in Neisseria Gonorrhoeae Isolates From Rio De Janeiro, Brazil
10.1016/j.meegid.2017.12.003 · 2018 · External reference
Genomic epidemiology of Neisseria gonorrhoeae in Shenzhen, China, during 2019–2020: Increased spread of ceftriaxone-resistant isolates brings insights for strengthening public health responses
10.1128/spectrum.01728-23 · 2023 · External reference
Surveillance systems to monitor antimicrobial resistance in Neisseria gonorrhoeae: a global, systematic review, 1 January 2012 to 27 September 2020
10.2807/1560-7917.es.2022.27.18.2100917 · 2022 · External reference
WGS of Commensal Neisseria Reveals Acquisition of a New Ribosomal Protection Protein (MsrD) as a Possible Explanation for High Level Azithromycin Resistance in Belgium
10.3390/pathogens10030384 · 2021 · External reference
Molecular epidemiological and antimicrobial-resistant mechanisms analysis of prolonged Neisseria gonorrhoeae collection between 1971 and 2005 in Japan
10.1093/jacamr/dlae040 · 2024 · External reference
Manure as a Potential Hotspot for Antibiotic Resistance Dissemination by Horizontal Gene Transfer Events
2020 · External reference
Metatranscriptomics Reveals Antibiotic-Induced Resistance Gene Expression in the Murine Gut Microbiota
10.3389/fmicb.2020.00322 · 2020 · External reference
Impact of bedaquiline and capreomycin on the gene expression patterns of multidrug-resistant Mycobacterium tuberculosis H37Rv strain and understanding the molecular mechanism of antibiotic resistance
10.1002/jcb.28711 · 2019 · External reference
Relevance of bacterial normal flora in antimicrobial resistance and how to overcome this resistance
10.21608/rpbs.2020.36348.1074 · 2020 · External reference
Investigation of Auranofin and Gold-Containing Analogues Antibacterial Activity Against Multidrug-Resistant Neisseria Gonorrhoeae
10.1038/s41598-020-62696-3 · 2020 · External reference
Antimicrobial susceptibilities of Neisseria gonorrhoeae in Canada, 2020
10.14745/ccdr.v48i1112a10 · 2022 · External reference
Structure-Activity Relationship Studies of Acetazolamide-Based Carbonic Anhydrase Inhibitors with Activity against Neisseria gonorrhoeae
10.1021/acsinfecdis.1c00055 · 2021 · External reference
Evaluation of Neisseria gonorrhoeae Isolates Susceptibility to Antibiotics in Zhejiang Province Since 2007
10.2147/idr.s396793 · 2023 · External reference
Whole-genome sequence analysis of high-level penicillin-resistant strains and antimicrobial susceptibility of Neisseria gonorrhoeae clinical isolates from Thailand
10.1371/journal.pone.0271657 · 2022 · External reference
Antimicrobial resistance in Neisseria gonorrhoeae in China: a meta-analysis
10.1186/s12879-016-1435-0 · 2016 · External reference
Genetic Characterization and Enhanced Surveillance of Ceftriaxone-Resistant Neisseria gonorrhoeae Strain, Alberta, Canada, 2018
10.3201/eid2509.190407 · 2019 · External reference
Australian gonococcal surveillance programme annual report, 2017
2019 · External reference
Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century: past, evolution, and future
10.1128/cmr.00010-14 · 2014 · External reference
In vitro activity and time-kill curve analysis of sitafloxacin against a global panel of antimicrobial-resistant and multidrug-resistant Neisseria gonorrhoeae isolates
10.1111/apm.12777 · 2018 · External reference
What’s left in the cupboard? Older antimicrobials for treating gonorrhoea
10.1093/jac/dkaa559 · 2021 · External reference
Inhibition of Neisseria gonorrhoeae Type II Topoisomerases by the Novel Spiropyrimidinetrione AZD0914
10.1074/jbc.m115.663534 · 2015 · External reference
Interactions between Zoliflodacin and Neisseria gonorrhoeae Gyrase and Topoisomerase IV: Enzymological Basis for Cellular Targeting
10.1021/acsinfecdis.4c00438 · 2024 · External reference
The Molecular Genetic Epidemiology and Antimicrobial Resistance of Neisseria gonorrhoeae Strains Obtained from Clinical Isolates in Central Panama
10.3390/microorganisms11102572 · 2023 · External reference
Emergence of quinolone resistance and cephalosporin MIC creep in Neisseria gonorrhoeae isolates from a cohort of young men in Kisumu, Kenya, 2002 to 2009
10.1128/aac.00155-11 · 2011 · External reference
Antimicrobial Susceptibility Patterns in Neisseria gonorrhoeae Isolated from South African Pregnant Women
10.1155/2021/6684680 · 2021 · External reference
Neisseria gonorrhoeae non-susceptible to cephalosporins and quinolones in Northwest Ethiopia
10.1186/1471-2334-13-415 · 2013 · External reference
