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References from Cryptosporidium parvum protease INS6 plays an important role in parasite proliferation and pathogenicity. Local targets link to admitted publications; unresolved targets remain external evidence.
Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study
10.1016/s0140-6736(13)60844-2 · 2013 · External reference
A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium
10.1016/s1473-3099(14)70772-8 · 2015 · External reference
Global, regional, and national age-sex specific mortality for 264 causes of death, 1980-2016: a systematic analysis for the Global Burden of Disease Study 2016
10.1016/s0140-6736(17)32152-9 · 2017 · External reference
Diarrhoeal disease and subsequent risk of death in infants and children residing in low-income and middle-income countries: analysis of the GEMS case-control study and 12-month GEMS-1A follow-on study
10.1016/s2214-109x(19)30541-8 · 2020 · External reference
Cryptosporidium parvum
10.1016/j.pt.2019.11.003 · 2020 · External reference
The biology of the intestinal intracellular parasite Cryptosporidium
10.1016/j.chom.2020.09.007 · 2020 · External reference
Modulation of innate immunity by Toxoplasma gondii virulence effectors
10.1038/nrmicro2858 · 2012 · External reference
Cryptosporidium uses multiple distinct secretory organelles to interact with and modify its host cell
10.1016/j.chom.2023.03.001 · 2023 · External reference
Transcriptional control of the Cryptosporidium life cycle
10.1038/s41586-024-07466-1 · 2024 · External reference
Toxoplasma gondii toxolysin 4 contributes to efficient parasite egress from host cells
10.1128/msphere.00444-21 · 2021 · External reference
Toxoplasma gondii toxolysin 4 is an extensively processed putative metalloproteinase secreted from micronemes
10.1016/j.molbiopara.2011.01.009 · 2011 · External reference
Comparative study of two insulinlike proteases in Cryptosporidium parvum
10.3390/microorganisms9040861 · 2021 · External reference
20 years of the SMART protein domain annotation resource
10.1093/nar/gkx922 · 2018 · External reference
Variant surface protein GP60 contributes to host infectivity of Cryptosporidium parvum
10.1038/s42003-024-06885-0 · 2024 · External reference
Diarrhoea outbreak caused by coinfections of Cryptosporidium parvum subtype IIdA20G1 and rotavirus in pre-weaned dairy calves
2022 · External reference
High infectivity and unique genomic sequence characteristics of Cryptosporidium parvum in China
2022 · External reference
SKSR1 identified as key virulence factor in Cryptosporidium by genetic crossing
10.1038/s41467-025-60088-7 · 2025 · External reference
Cryptosporidium oocyst purification using discontinuous gradient centrifugation
10.1007/978-1-4939-9748-0_4 · 2020 · External reference
A conditional protein degradation system to study essential gene function in Cryptosporidium parvum
10.1128/mbio.01231-20 · 2020 · External reference
A Stem-cell-derived platform enables complete Cryptosporidium development in vitro and genetic tractability
10.1016/j.chom.2019.05.007 · 2019 · External reference
Insulinase-like protease 1 contributes to macrogamont formation in Cryptosporidium parvum
2021 · External reference
Genetic modification of the diarrhoeal pathogen Cryptosporidium parvum
10.1038/nature14651 · 2015 · External reference
Genetic manipulation of Cryptosporidium parvum with CRISPR/Cas9
10.1007/978-1-4939-9748-0_13 · 2020 · External reference
Comparative genomic analysis of three intestinal species reveals reductions in secreted pathogenesis determinants in bovine-specific and non-pathogenic Cryptosporidium species
2020 · External reference
Coupling auxin-inducible degron system with ultrastructure expansion microscopy to accelerate the discovery of gene function in Toxoplasma gondii
10.1007/978-1-0716-1681-9_8 · 2021 · External reference
Characterization of NFDQ1 in Cryptosporidium parvum
10.1186/s13071-024-06532-x · 2024 · External reference
Live imaging of the Cryptosporidium parvum life cycle reveals direct development of male and female gametes from type I meronts
10.1371/journal.pbio.3001604 · 2022 · External reference
A lipid-binding protein mediates rhoptry discharge and invasion in Plasmodium falciparum and Toxoplasma gondii parasites
10.1038/s41467-019-11979-z · 2019 · External reference
Requirement of microtubules for secretion of a micronemal protein CpTSP4 in the invasive stage of the apicomplexan Cryptosporidium parvum
10.1128/mbio.03158-23 · 2024 · External reference
Toxoplasma FER1 is a versatile and dynamic mediator of differential microneme trafficking and microneme exocytosis
10.1038/s41598-024-72628-0 · 2024 · External reference
Mechanism of signal-anchor triage during early steps of membrane protein insertion
2023 · External reference
Molecular dissection of novel trafficking and processing of the Toxoplasma gondii rhoptry metalloprotease toxolysin-1
10.1111/j.1600-0854.2011.01308.x · 2012 · External reference
A conserved subtilisin-like protein TgSUB1 in microneme organelles of Toxoplasma gondii
10.1074/jbc.m106665200 · 2001 · External reference
Biogenesis and secretion of micronemes in Toxoplasma gondii
10.1111/cmi.13018 · 2019 · External reference
Evolution, composition, assembly, and function of the conoid in Apicomplexa
10.1016/j.pt.2020.05.001 · 2020 · External reference
Discovery of new microneme proteins in Cryptosporidium parvum and Implication of the Roles of a Rhomboid Membrane Protein (CpROM1) in host-parasite interaction
10.3389/fvets.2021.778560 · 2021 · External reference
The claudin-like apicomplexan microneme protein is required for gliding motility and infectivity of Plasmodium sporozoites
10.1371/journal.ppat.1011261 · 2023 · External reference
Shear forces enhance Toxoplasma gondii tachyzoite motility on vascular endothelium
10.1128/mbio.01111-13 · 2014 · External reference
The gamma interferon gene knockout mouse: a highly sensitive model for evaluation of therapeutic agents against Cryptosporidium parvum
10.1128/jcm.36.9.2503-2508.1998 · 1998 · External reference
Genetic diversity and population structure of Cryptosporidium
10.1016/j.pt.2018.07.009 · 2018 · External reference
The Cryptosporidium signaling kinase CDPK5 plays an important role in male gametogenesis and parasite virulence
10.1016/j.celrep.2024.114263 · 2024 · External reference