Research graph
References from Interleukin-10 limits immune-mediated pathology in chronic subclinical plasmodial infection. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
2023 · External reference
The pathogenic basis of malaria
10.1038/415673a · 2002 · External reference
Host-parasite interactions during Plasmodium infection: Implications for immunotherapies
10.3389/fimmu.2022.1091961 · 2023 · External reference
Sources of persistent malaria transmission in a setting with effective malaria control in eastern Uganda: a longitudinal, observational cohort study
10.1016/s1473-3099(21)00072-4 · 2021 · External reference
Regulating immunity to malaria
10.1111/j.1365-3024.2006.00775.x · 2006 · External reference
An intensive longitudinal cohort study of Malian children and adults reveals no evidence of acquired immunity to Plasmodium falciparum infection
10.1093/cid/cit174 · 2013 · External reference
Naturally Acquired Humoral Immunity Against Plasmodium falciparum Malaria
10.3389/fimmu.2020.594653 · 2020 · External reference
Asymptomatic Malaria Infection Is Maintained by a Balanced Pro- and Anti-inflammatory Response
10.3389/fmicb.2020.559255 · 2020 · External reference
Inflammatory cytokine responses in children with asymptomatic malaria infection living in rural, semi-urban and urban areas in south-eastern Gabon
10.1111/cei.13653 · 2021 · External reference
Role of interleukin 10 transcriptional regulation in inflammation and autoimmune disease
10.1615/critrevimmunol.v32.i1.30 · 2012 · External reference
The Role of IL-10 in Malaria: A Double Edged Sword
10.3389/fimmu.2019.00229 · 2019 · External reference
The ability of Interleukin-10 to negate haemozoin-related pro-inflammatory effects has the potential to restore impaired macrophage function associated with malaria infection
10.1186/s12936-023-04539-w · 2023 · External reference
Repeated clinical malaria episodes are associated with modification of the immune system in children
10.1186/s12916-019-1292-y · 2019 · External reference
Asymptomatic Plasmodium falciparum infection in children is associated with increased auto-antibody production, high IL-10 plasma levels and antibodies to merozoite surface protein 3
10.1186/s12936-015-0658-7 · 2015 · External reference
Cytokine response in asymptomatic and symptomatic Plasmodium falciparum infections in children in a rural area of south-eastern Gabon
10.1371/journal.pone.0280818 · 2023 · External reference
A role for B cells in the development of T cell helper function in a malaria infection in mice
10.1073/pnas.95.4.1730 · 1998 · External reference
A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene
10.1038/350423a0 · 1991 · External reference
Transformation of the rodent malaria parasite Plasmodium chabaudi and generation of a stable fluorescent line PcGFPCON
10.1186/1475-2875-7-183 · 2008 · External reference
Evaluating cytokine production by flow cytometry using brefeldin A in mice
10.1016/j.xpro.2020.100244 · 2020 · External reference
IL-17 mediates immunopathology in the absence of IL-10 following Leishmania major infection
10.1371/journal.ppat.1003243 · 2013 · External reference
Effect of a CD4-depleting antibody on the development of Cryptococcus neoformans-induced allergic bronchopulmonary mycosis in mice
10.1128/iai.01989-05 · 2006 · External reference
IL-27 promotes IL-10 production by effector Th1 CD4+ T cells: a critical mechanism for protection from severe immunopathology during malaria infection
10.4049/jimmunol.1102755 · 2012 · External reference
Dendritic cell responses to Plasmodium falciparum in a malaria-endemic setting
10.1186/s12936-020-03533-w · 2021 · External reference
IL-10 from CD4CD25Foxp3CD127 adaptive regulatory T cells modulates parasite clearance and pathology during malaria infection
10.1371/journal.ppat.1000004 · 2008 · External reference
IFNγ/IL-10 co-producing cells dominate the CD4 response to malaria in highly exposed children
10.1371/journal.ppat.1003864 · 2014 · External reference
Bone Marrow Plasma Cells Modulate Local Myeloid-Lineage Differentiation via IL-10
10.3389/fimmu.2019.01183 · 2019 · External reference
“Asymptomatic” Malaria: A Chronic and Debilitating Infection That Should Be Treated
10.1371/journal.pmed.1001942 · 2016 · External reference
Prevalence of Clinical and Subclinical Plasmodium falciparum and Plasmodium vivax Malaria in Two Remote Rural Communities on the Myanmar-China Border
10.4269/ajtmh.17-0167 · 2017 · External reference
Acquired immunity to malaria
10.1128/cmr.00025-08 · 2009 · External reference
Declining Malaria Transmission Differentially Impacts the Maintenance of Humoral Immunity to Plasmodium falciparum in Children
10.1093/infdis/jix370 · 2017 · External reference
Understanding P. falciparum Asymptomatic Infections: A Proposition for a Transcriptomic Approach
10.3389/fimmu.2019.02398 · 2019 · External reference
High affinity antibodies to Plasmodium falciparum merozoite antigens are associated with protection from malaria
10.1371/journal.pone.0032242 · 2012 · External reference
Haemolysis and haem oxygenase-1 induction during persistent “asymptomatic” malaria infection in Burkinabé children
10.1186/s12936-018-2402-6 · 2018 · External reference
“Bouncing Back” From Subclinical Malaria: Inflammation and Erythrocytosis After Resolution of P. falciparum Infection in Gambian Children
10.3389/fimmu.2022.780525 · 2022 · External reference
Long-lived antibody and B Cell memory responses to the human malaria parasites, Plasmodium falciparum and Plasmodium vivax
10.1371/journal.ppat.1000770 · 2010 · External reference
Naturally acquired IgG responses to Plasmodium falciparum do not target the conserved termini of the malaria vaccine candidate Merozoite Surface Protein 2
10.3389/fimmu.2024.1501700 · 2024 · External reference
Opsonising antibodies to P. falciparum merozoites associated with immunity to clinical malaria
2013 · External reference
A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasion-inhibiting antibodies
10.1084/jem.172.1.379 · 1990 · External reference
Human antibody response to the major merozoite surface antigen of Plasmodium falciparum is strain specific and short-lived
10.1128/iai.59.4.1319-1324.1991 · 1991 · External reference
Autoantibodies inhibit Plasmodium falciparum growth and are associated with protection from clinical malaria
10.1016/j.immuni.2024.05.024 · 2024 · External reference
The regulation of IL-10 production by immune cells
10.1038/nri2711 · 2010 · External reference
IL-10-producing Th1 cells possess a distinct molecular signature in malaria
10.1172/jci153733 · 2023 · External reference
The Development of Plasmodium falciparum-Specific IL10 CD4 T Cells and Protection from Malaria in Children in an Area of High Malaria Transmission
10.3389/fimmu.2017.01329 · 2017 · External reference
Type I regulatory T cells in malaria: of mice and men
10.1172/jci166019 · 2023 · External reference
CD4 T-cell subsets in malaria: TH1/TH2 revisited
10.3389/fimmu.2014.00671 · 2015 · External reference
Antibodies against merozoite surface protein (MSP)-1(19) are a major component of the invasion-inhibitory response in individuals immune to malaria
10.1084/jem.193.12.1403 · 2001 · External reference
Opsonization of malaria-infected erythrocytes activates the inflammasome and enhances inflammatory cytokine secretion by human macrophages
10.1186/1475-2875-11-343 · 2012 · External reference
Beyond binding: antibody effector functions in infectious diseases
10.1038/nri.2017.106 · 2018 · External reference
A Novel Model of Asymptomatic Plasmodium Parasitemia That Recapitulates Elements of the Human Immune Response to Chronic Infection
10.1371/journal.pone.0162132 · 2016 · External reference
