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References from Temporal and spatial profiling of Aedes albopictus immune responses to chikungunya virus infection. Local targets link to admitted publications; unresolved targets remain external evidence.
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10.3390/v6114628 · 2014 · External reference
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10.1086/605496 · 2009 · External reference
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10.1093/infdis/jiw285 · 2016 · External reference
Chikungunya virus: an update on the biology and pathogenesis of this emerging pathogen
2017 · External reference
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2019 · External reference
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Mosquito antiviral immune pathways
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Identification and characterization of the fibrinogen-like domain of fibrinogen-related proteins in the mosquito, Anopheles gambiae, and the fruitfly, Drosophila melanogaster, genomes
10.1186/1471-2164-6-114 · 2005 · External reference
Comparative and functional genomics of the innate immune system in the malaria vector Anopheles gambiae
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Conserved role of a complement-like protein in phagocytosis revealed by dsRNA knockout in cultured cells of the mosquito, Anopheles gambiae
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Leucine-rich repeat protein complex activates mosquito complement in defense against Plasmodium parasites
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Induced antiviral innate immunity in Drosophila
10.1016/j.mib.2014.05.006 · 2014 · External reference
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10.1073/pnas.0905006106 · 2009 · External reference
Characterization of Aedes aegypti innate-immune pathways that limit Chikungunya virus replication
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The Aedes aegypti toll pathway controls dengue virus infection
2008 · External reference
Aedes aegypti Molecular Responses to Zika Virus: Modulation of Infection by the Toll and Jak/Stat Immune Pathways and Virus Host Factors
10.3389/fmicb.2017.02050 · 2017 · External reference
Dengue virus inhibits immune responses in Aedes aegypti cells
2010 · External reference
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Aedes mosquito salivary immune peptides: boost or block dengue viral infections
2014 · External reference
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MicroRNA-8 targets the Wingless signaling pathway in the female mosquito fat body to regulate reproductive processes
10.1073/pnas.1424408112 · 2015 · External reference
Mosquito-specific microRNA-1890 targets the juvenile hormone-regulated serine protease JHA15 in the female mosquito gut
10.1080/15476286.2015.1101525 · 2015 · External reference
Mosquito-specific microRNA-1174 targets serine hydroxymethyltransferase to control key functions in the gut
10.1073/pnas.1416278111 · 2014 · External reference
MicroRNA levels are modulated in Aedes aegypti after exposure to Dengue-2
10.1111/imb.12070 · 2014 · External reference
Zika virus alters the microRNA expression profile and elicits an RNAi response in Aedes aegypti mosquitoes
10.1371/journal.pntd.0005760 · 2017 · External reference
Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus
10.1186/1471-2164-11-119 · 2010 · External reference
Effects of manipulating apoptosis on Sindbis virus infection of Aedes aegypti mosquitoes
10.1128/jvi.00125-12 · 2012 · External reference
The impact of autophagy on arbovirus infection of mosquito cells
10.1371/journal.pntd.0007754 · 2020 · External reference
Species-specific impact of the autophagy machinery on Chikungunya virus infection
10.1038/embor.2013.51 · 2013 · External reference
Recognition of Arboviruses by the Mosquito Immune System
10.3390/biom13071159 · 2023 · External reference
Phenoloxidase activity acts as a mosquito innate immune response against infection with Semliki Forest virus
10.1371/journal.ppat.1002977 · 2012 · External reference
Mosquito hemocyte-mediated immune responses
10.1016/j.cois.2014.07.002 · 2014 · External reference
RNASeq analysis of Aedes albopictus Mosquito Midguts after Chikungunya Virus Infection
10.3390/v11060513 · 2019 · External reference
Whole Transcriptome Analysis of Aedes albopictus Mosquito Head and Thorax Post-Chikungunya Virus Infection
10.3390/pathogens8030132 · 2019 · External reference
Midgut transcriptomic responses to dengue and chikungunya viruses in the vectors Aedes albopictus and Aedes malayensis
10.1038/s41598-023-38354-9 · 2023 · External reference
Vector competence of Italian Aedes albopictus populations for the chikungunya virus (E1-226V)
10.1371/journal.pntd.0006435 · 2018 · External reference
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10.1093/bioinformatics/btu170 · 2014 · External reference
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
10.1186/gb-2009-10-3-r25 · 2009 · External reference
RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
10.1186/1471-2105-12-323 · 2011 · External reference
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
10.1093/bioinformatics/btp616 · 2010 · External reference
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10.1093/dnares/dsu001 · 2014 · External reference
The Pfam protein families database
2010 · External reference
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Unresolved reference
2011 · External reference
Genome Investigations of Vector Competence in Aedes aegypti to Inform Novel Arbovirus Disease Control Approaches
10.3390/insects7040058 · 2016 · External reference
Mosquito Innate Immunity
10.3390/insects9030095 · 2018 · External reference
aBravo Is a Novel Aedes aegypti Antiviral Protein that Interacts with, but Acts Independently of, the Exogenous siRNA Pathway Effector Dicer 2
10.3390/v12070748 · 2020 · External reference
Argonaute 2 Suppresses Japanese Encephalitis Virus Infection in Aedes aegypti
10.7883/yoken.jjid.2015.671 · 2017 · External reference
An Aedes aegypti-Derived Ago2 Knockout Cell Line to Investigate Arbovirus Infections
10.3390/v13061066 · 2021 · External reference
GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme
10.1016/j.molcel.2021.03.025 · 2021 · External reference
UHRF1 Suppresses HIV-1 Transcription and Promotes HIV-1 Latency by Competing with p-TEFb for Ubiquitination-Proteasomal Degradation of Tat
10.1128/mbio.01625-21 · 2021 · External reference
The role of ubiquitylation in immune defence and pathogen evasion
10.1038/nri3111 · 2011 · External reference
Decoding the ubiquitin-mediated pathway of arthropod disease vectors
10.1371/journal.pone.0078077 · 2013 · External reference
Comprehensive genetic dissection of the hemocyte immune response in the malaria mosquito Anopheles gambiae
10.1371/journal.ppat.1003145 · 2013 · External reference
Proteomic identification of dengue virus binding proteins in Aedes aegypti mosquitoes and Aedes albopictus cells
2013 · External reference
Transcriptomic Analysis of Aedes aegypti Innate Immune System in Response to Ingestion of Chikungunya Virus
10.3390/ijms20133133 · 2019 · External reference
Mosquito cellular factors and functions in mediating the infectious entry of chikungunya virus
2013 · External reference
Functional entry of dengue virus into Aedes albopictus mosquito cells is dependent on clathrin-mediated endocytosis
10.1099/vir.0.83357-0 · 2008 · External reference
Inter-cell type interactions that control JNK signaling in the Drosophila intestine
10.1038/s41467-024-49786-w · 2024 · External reference
Flaviviruses manipulate mitochondrial processes to evade the innate immune response
10.1038/s44298-024-00057-x · 2024 · External reference
Dengue virus non-structural protein 3 inhibits mitochondrial respiration by impairing complex I function
10.1128/msphere.00406-24 · 2024 · External reference
Histone acetylation mediates epigenetic regulation of transcriptional reprogramming in insects during metamorphosis, wounding and infection
10.1186/1742-9994-9-25 · 2012 · External reference
Epigenetic remodeling in insect immune memory
10.3389/fimmu.2024.1397521 · 2024 · External reference
Complex modulation of the Aedes aegypti transcriptome in response to dengue virus infection
10.1371/journal.pone.0050512 · 2012 · External reference
Transcriptome analysis of Aedes aegypti Aag2 cells in response to dengue virus-2 infection
10.1186/s13071-020-04294-w · 2020 · External reference
Interplay between Zika Virus and Peroxisomes during Infection
10.3390/cells8070725 · 2019 · External reference
Immunoglobulin superfamily members play an important role in the mosquito immune system
10.1016/j.dci.2007.09.007 · 2008 · External reference
A mosquito hemolymph odorant-binding protein family member specifically binds juvenile hormone
10.1074/jbc.m117.802009 · 2017 · External reference
A mosquito juvenile hormone binding protein (mJHBP) regulates the activation of innate immune defenses and hemocyte development
2020 · External reference
Integrins in the Immunity of Insects: A Review
10.3389/fimmu.2022.906294 · 2022 · External reference
Structural and functional characterization of pseudopodocyte, a shaggy immune cell produced by two Drosophila species of the obscura group
10.1016/j.dci.2011.05.009 · 2012 · External reference
Genome-Wide Analysis of Major Facilitator Superfamily and Its Expression in Response of Poplar to Fusarium oxysporum
10.3389/fgene.2021.769888 · 2021 · External reference
Mucin Protein of Aedes aegypti Interacts with Dengue Virus 2 and Influences Viral Infection
2023 · External reference
Implications of mosquito metabolism on vector competence
10.1111/1744-7917.13288 · 2024 · External reference
Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes
10.1126/science.1139862 · 2007 · External reference
Sequence-structure-function relations of the mosquito leucine-rich repeat immune proteins
10.1186/1471-2164-11-531 · 2010 · External reference
Improved reference genome of the arboviral vector Aedes albopictus
10.1186/s13059-020-02141-w · 2020 · External reference
RNA interference is essential to modulating the pathogenesis of mosquito-borne viruses in the yellow fever mosquito Aedes aegypti
10.1073/pnas.2213701120 · 2023 · External reference
The midgut transcriptome of Aedes aegypti fed with saline or protein meals containing chikungunya virus reveals genes potentially involved in viral midgut escape
10.1186/s12864-017-3775-6 · 2017 · External reference
Re-evaluating the mosquito RNAi pathway’s influence on arbovirus transmission
10.1016/j.pt.2023.09.005 · 2023 · External reference
Aedes aegypti microRNA miR-2b regulates ubiquitin-related modifier to control chikungunya virus replication
10.1038/s41598-017-18043-0 · 2017 · External reference
A novel mosquito ubiquitin targets viral envelope protein for degradation and reduces virion production during dengue virus infection
10.1016/j.bbagen.2016.05.033 · 2016 · External reference
An Aedes aegypti-associated fungus increases susceptibility to dengue virus by modulating gut trypsin activity
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The Role of Mosquito Hemocytes in Viral Infections
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CAMPR3: a database on sequences, structures and signatures of antimicrobial peptides
10.1093/nar/gkv1051 · 2016 · External reference
A transcriptomic atlas of Aedes aegypti reveals detailed functional organization of major body parts and gut regional specializations in sugar-fed and blood-fed adult females
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An insight into the sialotranscriptome of the cat flea, Ctenocephalides felis
2012 · External reference
Controlling arbovirus infection: high-throughput transcriptome and proteome insights
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Multifaceted contributions of Dicer2 to arbovirus transmission by Aedes aegypti
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RNA interference, arthropod-borne viruses, and mosquitoes
10.1016/j.virusres.2004.01.017 · 2004 · External reference
Mosquito RNAi is the major innate immune pathway controlling arbovirus infection and transmission
10.2217/fmb.11.11 · 2011 · External reference
Suppression of RNA interference increases alphavirus replication and virus-associated mortality in Aedes aegypti mosquitoes
10.1186/1471-2180-9-49 · 2009 · External reference
The role of ubiquitination in Drosophila innate immunity
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Novel factors of Anopheles gambiae haemocyte immune response to Plasmodium berghei infection
10.1186/s13071-016-1359-y · 2016 · External reference
Dengue virus reduces expression of low-density lipoprotein receptor-related protein 1 to facilitate replication in Aedes aegypti
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Lipid metabolism in insect disease vectors
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Lipin modulates lipid metabolism during reproduction in the cabbage beetle
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Response of the mosquito immune system and symbiotic bacteria to pathogen infection
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Transcriptome analysis of Aedes albopictus midguts infected by dengue virus identifies a gene network module highly associated with temperature
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Chikungunya virus dissemination from the midgut of Aedes aegypti is associated with temporal basal lamina degradation during bloodmeal digestion
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Transcriptional Profile of Aedes aegypti Leucine-Rich Repeat Proteins in Response to Zika and Chikungunya Viruses
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Complement-related proteins control the flavivirus infection of Aedes aegypti by inducing antimicrobial peptides
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Expression of fatty acid synthase genes and their role in development and arboviral infection of Aedes aegypti
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Lipids as a key element of insect defense systems
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Delineating the Role of Aedes aegypti ABC Transporter Gene Family during Mosquito Development and Arboviral Infection via Transcriptome Analyses
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Plasmodium infection alters Anopheles gambiae detoxification gene expression
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