Research graph
References from NFATc1 regulates LAG3+CD8+ T cells in the spleen of mice infected with Plasmodium yoelii NSM. Local targets link to admitted publications; unresolved targets remain external evidence.
Trends of neglected Plasmodium species infection in humans over the past century in India
10.1016/j.onehlt.2020.100190 · 2020 · External reference
Synthesis, Molecular Docking and Antiplasmodial Activities of New Tetrahydro-β-Carbolines
10.3390/ijms222413569 · 2021 · External reference
WHO world malaria report 2024
10.1016/j.lanmic.2025.101073 · 2025 · External reference
The many paths to artemisinin resistance in Plasmodium falciparum
10.1016/j.pt.2023.09.011 · 2023 · External reference
Properties and Roles of γδT Cells in Plasmodium yoelii nigeriensis NSM Infected C57BL/6 Mice
10.3389/fcimb.2021.788546 · 2022 · External reference
Targeted Delivery of Nanovaccine to Dendritic Cells via DC-Binding Peptides Induces Potent Antiviral Immunity in vivo
10.2147/ijn.s357462 · 2022 · External reference
Memory CD8+ T cell-mediated protection against liver-stage malaria
10.1111/imr.13202 · 2023 · External reference
Systems analysis of immune responses to attenuated P. falciparum malaria sporozoite vaccination reveals excessive inflammatory signatures correlating with impaired immunity
2022 · External reference
Expeditious recruitment of circulating memory CD8 T cells to the liver facilitates control of malaria
10.1016/j.celrep.2021.109956 · 2021 · External reference
CD8+ T cell exhaustion
10.1007/s00281-019-00744-5 · 2019 · External reference
Increased Expression of Multiple Co-Inhibitory Molecules on Malaria-Induced CD8+ T Cells Are Associated With Increased Function Instead of Exhaustion
10.3389/fimmu.2022.878320 · 2022 · External reference
T cells expressing multiple co-inhibitory molecules in acute malaria are not exhausted but exert a suppressive function in mice
10.1002/eji.202149424 · 2022 · External reference
Cutting edge: molecular analysis of the negative regulatory function of lymphocyte activation gene-3
10.4049/jimmunol.169.10.5392 · 2002 · External reference
The negative regulatory function of the lymphocyte-activation gene-3 co-receptor (CD223) on human T cells
10.1111/j.1365-2567.2005.02145.x · 2005 · External reference
Blockade of LAG-3 in PD-L1-Deficient Mice Enhances Clearance of Blood Stage Malaria Independent of Humoral Responses
10.3389/fimmu.2020.576743 · 2021 · External reference
PD-1+ CD4 T cell immune response is mediated by HIF-1α/NFATc1 pathway after P. yoelii infection
10.3389/fimmu.2022.942862 · 2022 · External reference
Role of NFATc1 in the Bone-Vascular Axis Calcification Paradox
10.1097/fjc.0000000000000788 · 2020 · External reference
NFATc1 and NFATc2 together control both T and B cell activation and differentiation
10.1016/s1074-7613(01)00085-1 · 2001 · External reference
Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum
10.1038/32419 · 1998 · External reference
The Role of Ca2+-NFATc1 Signaling and Its Modulation on Osteoclastogenesis
10.3390/ijms21103646 · 2020 · External reference
Memory T cell, exhaustion, and tumor immunity
10.1080/25785826.2019.1698261 · 2020 · External reference
LAG3 associates with TCR-CD3 complexes and suppresses signaling by driving co-receptor-Lck dissociation
10.1038/s41590-022-01176-4 · 2022 · External reference
Checkpoint Inhibition and Infectious Diseases: A Good Thing?
10.1016/j.molmed.2019.08.004 · 2019 · External reference
Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection
10.1073/pnas.1009731107 · 2010 · External reference
The immunoreceptor TIGIT regulates antitumor and antiviral CD8(+) T cell effector function
10.1016/j.ccell.2014.10.018 · 2014 · External reference
TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells
10.1038/nature25501 · 2018 · External reference
CD69 is a Promising Immunotherapy and Prognosis Prediction Target in Cancer
10.2147/itt.s439969 · 2024 · External reference
ICOS: a new costimulatory ligand/receptor pair and its role in T-cell activion
2004 · External reference
IL-2Rα-biased agonist enhances antitumor immunity by invigorating tumor-infiltrating CD25+CD8+ T cells
10.1038/s43018-023-00612-0 · 2023 · External reference
CD38: a multi-lineage cell activation molecule with a split personality
10.1007/bf02591400 · 1992 · External reference
The spleen: “epicenter” in malaria infection and immunity
10.1002/jlb.4ri1020-713r · 2021 · External reference
The Human Spleen in Malaria: Filter or Shelter?
10.1016/j.pt.2020.03.001 · 2020 · External reference
Retention of uninfected red blood cells causing congestive splenomegaly is the major mechanism of anemia in malaria
10.1002/ajh.27152 · 2024 · External reference
Malaria induces anemia through CD8+ T cell-dependent parasite clearance and erythrocyte removal in the spleen
10.1128/mbio.02493-14 · 2015 · External reference
The promising immune checkpoint LAG-3 in cancer immunotherapy: from basic research to clinical application
10.3389/fimmu.2022.956090 · 2022 · External reference
Analysis of Co-inhibitory Receptor Expression in COVID-19 Infection Compared to Acute Plasmodium falciparum Malaria: LAG-3 and TIM-3 Correlate With T Cell Activation and Course of Disease
10.3389/fimmu.2020.01870 · 2020 · External reference
Expression regulation of co-inhibitory molecules on human natural killer cells in response to cytokine stimulations
10.1016/j.cyto.2013.09.016 · 2014 · External reference
T cell exhaustion
10.1038/ni.2035 · 2011 · External reference
CD25: A potential tumor therapeutic target
10.1002/ijc.34281 · 2023 · External reference
CD69: from activation marker to metabolic gatekeeper
10.1002/eji.201646837 · 2017 · External reference
ICOS Co-Stimulation: Friend or Foe?
10.3389/fimmu.2016.00304 · 2016 · External reference
Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape
10.1158/0008-5472.can-11-1620 · 2012 · External reference
Impaired NFAT nuclear translocation results in split exhaustion of virus-specific CD8+ T cell functions during chronic viral infection
10.1073/pnas.0610335104 · 2007 · External reference
Impaired NFAT transcriptional activity in antigen-stimulated CD8 T cells linked to defective phosphorylation of NFAT transactivation domain
10.4049/jimmunol.0803539 · 2009 · External reference
