Research graph
References from Methotrexate and Prednisolone compared to placebo and prednisolone in the treatment of severe Erythema Nodosum Leprosum: An international multicentre, double-blind randomised controlled clinical trial—MaPs in ENL. Local targets link to admitted publications; unresolved targets remain external evidence.
Leprosy
10.1038/s41572-024-00575-1 · 2024 · External reference
Global leprosy (Hansen disease) update, 2024: Beyond zero cases - what elimination of leprosy really means
2025 · External reference
Epidemiological characteristics of leprosy reactions: 15 years experience from North India
10.1489/1544-581x(2004)072<0125:ecolry>2.0.co;2 · 2004 · External reference
Uniform multidrug therapy for leprosy patients in Brazil (U-MDT/CT-BR): Results of an open label, randomized and controlled clinical trial, among multibacillary patients
10.1371/journal.pntd.0005725 · 2017 · External reference
The incidence of erythema nodosum leprosum in India: a retrospective follow-up of the INFIR cohort
10.47276/lr.89.3.321 · 2018 · External reference
Clinical course of erythema nodosum leprosum: An 11-year cohort study in Hyderabad, India
10.4269/ajtmh.2006.74.868 · 2006 · External reference
A systematic review on the epidemiological data of erythema nodosum leprosum, a type 2 leprosy reaction
2013 · External reference
ENLIST 1: An International multi-centre cross-sectional study of the clinical features of erythema nodosum leprosum
10.1371/journal.pntd.0004065 · 2015 · External reference
Health-related quality of life amongst people affected by erythema nodosum leprosum in Bangladesh: A cross sectional study
10.47276/lr.88.4.488 · 2017 · External reference
Health-related quality of life associated with erythema nodosum leprosum in Purulia, West Bengal, India
10.47276/lr.91.1.100 · 2020 · External reference
The impact of erythema nodosum leprosum on health related quality of life in Rio de Janeiro
10.47276/lr.88.4.499 · 2017 · External reference
Household costs of leprosy reactions (ENL) in rural India
10.1371/journal.pntd.0003431 · 2015 · External reference
A systematic review of immunological studies of erythema nodosum leprosum
10.3389/fimmu.2017.00233 · 2017 · External reference
Regulatory T cells in erythema nodosum leprosum maintain anti-inflammatory function
10.1371/journal.pntd.0010641 · 2022 · External reference
The effects of prednisolone treatment on cytokine expression in patients with erythema nodosum leprosum reactions
10.3389/fimmu.2018.00189 · 2018 · External reference
Clinico-pathological features of erythema nodosum leprosum: A case-control study at ALERT hospital, Ethiopia
10.1371/journal.pntd.0006011 · 2017 · External reference
Unresolved reference
2017 · External reference
The mortality associated with erythema nodosum leprosum in Ethiopia: A retrospective hospital-based study
10.1371/journal.pntd.0002690 · 2014 · External reference
A systematic review of adverse effects associated with systemic corticosteroids in the management of leprosy
External reference
Retrospective study of the morbidity associated with erythema nodosum leprosum in Brazilian leprosy patients
10.47276/lr.90.1.68 · 2019 · External reference
Erythema nodosum leprosum in Nepal: A retrospective study of clinical features and response to treatment with prednisolone or thalidomide
10.47276/lr.79.3.254 · 2008 · External reference
Thalidomide in the treatment of erythema nodosum leprosum (ENL) in an outpatient setting: A five-year retrospective analysis from a leprosy referral centre in India
10.1371/journal.pntd.0008678 · 2020 · External reference
Comparative efficacy of thalidomide and prednisolone in the treatment of moderate to severe erythema nodosum leprosum: A randomized study
10.1111/j.1440-0960.2009.00534.x · 2009 · External reference
A randomized placebo-controlled trial of methotrexate in psoriatic arthritis
10.1093/rheumatology/kes001 · 2012 · External reference
Application and pharmacological mechanism of methotrexate in rheumatoid arthritis
10.1016/j.biopha.2022.113074 · 2022 · External reference
2021 American College of Rheumatology guideline for the treatment of rheumatoid arthritis
10.1002/acr.24596 · 2021 · External reference
Methotrexate in resistant juvenile rheumatoid arthritis
1992 · External reference
British Association of Dermatologists’ guidelines for the safe and effective prescribing of methotrexate for skin disease 2016
10.1111/bjd.14816 · 2016 · External reference
Efficacy and safety of prednisolone monotherapy versus prednisolone plus methotrexate in erythema nodosum leprosum (type 2 lepra reaction)
10.1097/jd9.0000000000000133 · 2020 · External reference
International workshop on erythema nodosum leprosum (ENL) - consensus report; the formation of ENLIST, the ENL International STudy group
10.47276/lr.83.4.396 · 2012 · External reference
Methotrexate and prednisolone study in erythema nodosum leprosum (MaPs in ENL) protocol: A double-blind randomised clinical trial
10.1136/bmjopen-2020-037700 · 2020 · External reference
A leprosy clinical severity scale for erythema nodosum leprosum: An international, multicentre validation study of the ENLIST ENL Severity Scale
10.1371/journal.pntd.0005716 · 2017 · External reference
Dermatology life quality index (DLQI)—a simple practical measure for routine clinical use
1994 · External reference
SF-36 health survey manual and interpretation guide
1993 · External reference
Interventions for erythema nodosum leprosum. A cochrane review
10.47276/lr.80.4.355 · 2009 · External reference
Effectiveness and safety of clofazimine and pentoxifylline in type 2 lepra reaction: A double-blind, randomized, controlled study
10.1111/ijd.12793 · 2015 · External reference
Comparison of efficacy and safety of ciclosporin to prednisolone in the treatment of erythema nodosum leprosum: Two randomised, double blind, controlled pilot studies in Ethiopia
10.1371/journal.pntd.0004149 · 2016 · External reference
Methotrexate as a corticosteroid-sparing agent in leprosy reactions: A French multicenter retrospective study. (GrIDIST) G d’infectiologie en dermatologie et des infections sexuellement transmissibles, editor
10.1371/journal.pntd.0011238 · 2023 · External reference
Methotrexate an old drug with new tricks
10.3390/ijms20205023 · 2019 · External reference
Treatment of recurrent erythema nodosum leprosum with infliximab
10.1056/nejmc052955 · 2006 · External reference
Treatment of severe refractory erythema nodosum leprosum with tumor necrosis factor inhibitor Etanercept
10.1016/j.ijmyco.2016.02.002 · 2016 · External reference
Severe refractory erythema nodosum leprosum successfully treated with the tumor necrosis factor inhibitor etanercept
10.1093/cid/ciq213 · 2011 · External reference
Can etanercept be an option in management of recurrent steroid-dependent erythema nodosum leprosum? A retrospective study of six patients
10.25259/ijdvl_726_20 · 2022 · External reference
Biologics in leprosy: A systematic review and case report
10.4269/ajtmh.19-0616 · 2020 · External reference
Randomised comparison of thalidomide versus placebo in toxic epidermal necrolysis
10.1016/s0140-6736(98)02197-7 · 1998 · External reference
The role of thalidomide in the management of erythema nodosum leprosum
10.47276/lr.78.3.197 · 2007 · External reference
Access to thalidomide
10.47276/lr.94.3.186 · 2023 · External reference
Methotrexate treatment for type 1 (reversal) leprosy reactions
10.1086/518699 · 2007 · External reference
Mycobacteria.
2016 · External reference
Cytokine and protein markers of leprosy reactions in skin and nerves: baseline results for the North Indian INFIR cohort
2011 · External reference
Efficacy and gastrointestinal tolerability of methotrexate in late-onset rheumatoid arthritis patients: A prospective cohort study
10.1186/s43166-023-00178-w · 2023 · External reference
Low-dose methotrexate and serious adverse events among older adults with chronic kidney disease
10.1001/jamanetworkopen.2023.45132 · 2023 · External reference
Adverse effects of low-dose methotrexate: A randomized trial
10.7326/m19-3369 · 2020 · External reference
Rates and predictors of methotrexate-related adverse events in patients with early rheumatoid arthritis: results from a nationwide UK study
10.1093/rheumatology/keab917 · 2022 · External reference