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References from Winning the endgame against sleeping sickness: Efficacy profiling of acoziborole against African trypanosomes with the focus on Trypanosoma brucei rhodesiense. Local targets link to admitted publications; unresolved targets remain external evidence.
Fexinidazole--a new oral nitroimidazole drug candidate entering clinical development for the treatment of sleeping sickness
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Oral fexinidazole for stage 1 or early stage 2 African Trypanosoma brucei gambiense trypanosomiasis: a prospective, multicentre, open-label, cohort study
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Fexinidazole for Human African Trypanosomiasis, the Fruit of a Successful Public-Private Partnership
10.3390/diseases10040090 · 2022 · External reference
New WHO guidelines for treatment of gambiense human African trypanosomiasis including fexinidazole: substantial changes for clinical practice
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New WHO guidelines for treating rhodesiense human African trypanosomiasis: expanded indications for fexinidazole and pentamidine
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Determination of an optimal dosing regimen for fexinidazole, a novel oral drug for the treatment of human African trypanosomiasis: first-in-human studies
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10.1016/s1473-3099(22)00660-0 · 2023 · External reference
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10.1371/journal.pntd.0001668 · 2012 · External reference
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Pharmacokinetics and pharmacodynamics utilizing unbound target tissue exposure as part of a disposition-based rationale for lead optimization of benzoxaboroles in the treatment of Stage 2 Human African Trypanosomiasis
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Mass balance, pharmacokinetics, metabolism, and excretion of radiolabeled acoziborole, a potential novel treatment for human African trypanosomiasis, following single microtracer oral dose to humans
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