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References from MiR-155 Induction by F. novicida but Not the Virulent F. tularensis Results in SHIP Down-Regulation and Enhanced Pro-Inflammatory Cytokine Response. Local targets link to admitted publications; unresolved targets remain external evidence.
Phagocytosis and Killing of Francisella-Tularensis by Human Polymorphonuclear Leukocytes.
10.1128/iai.39.2.715-720.1983 · 1983 · External reference
Francisella tularensis induces cytopathogenicity and apoptosis in murine macrophages via a mechanism that requires intracellular bacterial multiplication.
10.1128/iai.69.7.4691-4694.2001 · 2001 · External reference
Uptake and intracellular fate of Francisella tularensis in human macrophages. Francisella Tularensis: Biology, Pathogenicity, Epidemiology, and Biodefense.
10.1196/annals.1409.001 · 2007 · External reference
Tularaemia: Bioterrorism defence renews interest in Francisella tularensis.
10.1038/nrmicro1045 · 2004 · External reference
Francisella tularensis: taxonomy, genetics, and Immunopathogenesis of a potential agent of biowarfare.
10.1146/annurev.micro.60.080805.142126 · 2006 · External reference
Tularemia: emergence/re-emergence.
10.1051/vetres:2005006 · 2005 · External reference
Tularemia.
10.1128/cmr.15.4.631-646.2002 · 2002 · External reference
Francisella gains a survival advantage within mononuclear phagocytes by suppressing the host IFN gamma response.
10.1016/j.molimm.2008.04.006 · 2008 · External reference
Francisella tularensis inhibits Toll-like receptor-mediated activation of intracellular signalling and secretion of TNF-alpha and IL-1 from murine macrophages.
10.1046/j.1462-5822.2003.00251.x · 2003 · External reference
Lack of in vitro and in vivo recognition of Francisella tularensis subspecies lipopolysaccharide by Toll-like receptors.
10.1128/iai.00934-06 · 2006 · External reference
Microarray analysis of human monocytes infected with Francisella tularensis identifies new targets of host response subversion.
10.1371/journal.pone.0002924 · 2008 · External reference
Active suppression of the pulmonary immune response by Francisella tularensis Schu4.
10.4049/jimmunol.178.7.4538 · 2007 · External reference
The structure and function of Francisella lipopolysaccharide.
2007 · External reference
Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS.
10.1128/iai.74.5.2809-2816.2006 · 2006 · External reference
Toll-like receptor 2 is required for control of pulmonary infection with Francisella tularensis.
10.1128/iai.02030-05 · 2006 · External reference
Administration of a synthetic TLR4 agonist protects mice from pneumonic tularemia.
10.4049/jimmunol.180.11.7574 · 2008 · External reference
Macrophage pro-inflammatory response to Francisella novicida infection is regulated by SHIP.
2006 · External reference
Akt/protein kinase B modulates macrophage inflammatory response to Francisella infection and confers a survival advantage in mice.
10.4049/jimmunol.177.9.6317 · 2006 · External reference
Akt and SHIP Modulate Francisella Escape from the Phagosome and Induction of the Fas-Mediated Death Pathway.
10.1371/journal.pone.0007919 · 2009 · External reference
Cell biology and molecular ecology of Francisella tularensis.
2009 · External reference
Inositol phosphatase SHIP1 is a primary target of miR-155.
10.1073/pnas.0902636106 · 2009 · External reference
Role of microRNAs in plant and animal development.
10.1126/science.1085242 · 2003 · External reference
NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses.
10.1073/pnas.0605298103 · 2006 · External reference
MicroRNA-155 is induced during the macrophage inflammatory response.
10.1073/pnas.0610731104 · 2007 · External reference
Accumulation of miR-155 and BIC RNA in human B cell lymphomas.
10.1073/pnas.0500613102 · 2005 · External reference
MicroRNA-155 regulates human angiotensin II type 1 receptor expression in fibroblasts.
10.1074/jbc.m601496200 · 2006 · External reference
B-cell receptor activation induces BIC/miR-155 expression through a conserved AP-1 element.
10.1074/jbc.m708218200 · 2008 · External reference
Achieving stability of lipopolysaccharide-induced NF-kappaB activation.
10.1126/science.1112304 · 2005 · External reference
Regulation and function of NF-kappaB transcription factors in the immune system.
10.1146/annurev.immunol.021908.132641 · 2009 · External reference
Epstein-Barr virus latent membrane protein 1 trans-activates miR-155 transcription through the NF-kappa B pathway.
10.1093/nar/gkn666 · 2008 · External reference
The tyrosine kinase Syk promotes phagocytosis of Francisella through the activation of Erk.
10.1016/j.molimm.2008.01.011 · 2008 · External reference
The Francisella tularensis pathogenicity island protein IglC and its regulator MglA are essential for modulating phagosome biogenesis and subsequent bacterial escape into the cytoplasm.
10.1111/j.1462-5822.2005.00526.x · 2005 · External reference
Internalization and phagosome escape required for Francisella to induce human monocyte IL-1 beta processing and release.
10.1073/pnas.0504271103 · 2006 · External reference
Type I interferon signaling is required for activation of the inflammasome during Francisella infection.
10.1084/jem.20062665 · 2007 · External reference
The inositol phosphatase SHIP inhibits Akt/PKB activation in B cells.
10.1074/jbc.273.51.33922 · 1998 · External reference
Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice.
10.1073/pnas.0602266103 · 2006 · External reference
The human angiotensin II type 1 receptor+1166 A/C polymorphism attenuates MicroRNA-155 binding.
10.1074/jbc.m701050200 · 2007 · External reference
Shhh! Silencing by microRNA-155.
10.1098/rstb.2008.0209 · 2009 · External reference
Multiple Proto-Oncogene Activations in Avian-Leukosis Virus-Induced Lymphomas - Evidence for Stage-Specific Events.
10.1128/mcb.9.6.2657 · 1989 · External reference
bic, a novel gene activated by proviral insertions in avian leukosis virus-induced lymphomas, is likely to function through its noncoding RNA.
10.1128/mcb.17.3.1490 · 1997 · External reference
A viral microRNA functions as an orthologue of cellular miR-155.
10.1038/nature05992 · 2007 · External reference
A Functional MicroRNA-155 Ortholog Encoded by the Oncogenic Marek's Disease Virus.
10.1128/jvi.01166-08 · 2008 · External reference
Epstein-Barr Virus-Induced miR-155 Attenuates NF-kappa B Signaling and Stabilizes Latent Virus Persistence.
10.1128/jvi.00752-08 · 2008 · External reference
microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells.
10.1016/j.immuni.2007.10.009 · 2007 · External reference
Regulation of the germinal center response by microRNA-155.
10.1126/science.1141229 · 2007 · External reference
Targeting the SH2 Domain-Containing Inositol Phosphatase (SHIP) for Therapy.
2009 · External reference
Critical role for serum opsonins and complement receptors CR3 (CD11b/CD18) and CR4 (CD11c/CD18) in phagocytosis of Francisella tularensis by human dendritic cells (DC): uptake of Francisella leads to activation of immature DC and intracellular survival of the bacteria.
10.1189/jlb.1205755 · 2006 · External reference
Differential infection of mononuclear phagocytes by Francisella tularensis: role of the macrophage mannose receptor.
10.1189/jlb.0306219 · 2006 · External reference
Evasion of complement-mediated lysis and complement C3 deposition are regulated by Francisella tularensis lipopolysaccharide O antigen.
10.4049/jimmunol.181.8.5568 · 2008 · External reference
Presence of CD14 overcomes evasion of innate immune responses by virulent Francisella tularensis in human dendritic cells in vitro and pulmonary cells in vivo.
2009 · External reference
Involvement of SHIP in TLR2-induced neutrophil activation and acute lung injury.
10.4049/jimmunol.174.12.8064 · 2005 · External reference
Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder.
10.1084/jem.20072108 · 2008 · External reference
Targeted disruption of ship leads to hemopoietic perturbations, lung pathology, and a shortened lifespan.
1998 · External reference
