Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Privacy-aware community infrastructureResearch graph
References from RETRACTED: Identification of Sumoylation Sites in CCDC6, the First Identified RET Partner Gene in Papillary Thyroid Carcinoma, Uncovers a Mode of Regulating CCDC6 Function on CREB1 Transcriptional Activity. Local targets link to admitted publications; unresolved targets remain external evidence.
PTC is a novel rearranged form of the RET proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas
10.1016/0092-8674(90)90659-3 · 1990 · External reference
Pathogenetic mechanisms in thyroid follicular-cell neoplasia
10.1038/nrc1836 · 2006 · External reference
Molecular characterization of RET/PTC 3: a novel rearranged version of the RET proto-oncogene in a human thyroid papillary carcinoma
1994 · External reference
RET/PTC activation in papillary thyroid carcinoma
10.1530/eje.1.02289 · 2006 · External reference
Characterization of an inversion on the long arm of chromosome 10 juxtaposing D10S170 and RET and creating the oncogenic sequence RET/PTC
10.1073/pnas.89.5.1616 · 1992 · External reference
RET, ROS1 and ALK fusions in lung cancer
10.1038/nm.2658 · 2012 · External reference
Fusion of H4/D10S170 to PDGFRbeta in a patient with chronicmyelomonocytic leukemia and long-term responsiveness to imatinib
10.1007/s00277-006-0247-5 · 2007 · External reference
Characterization of novel non-clonal intrachromosomal rearrangements between the H4 and PTEN genes (H4/PTEN) in human thyroid cell lines and papillary thyroid cancer specimens
2005 · External reference
Cloning and characterization of H4 (D10S170), a gene involved in RET rearrangements in vivo
1994 · External reference
Leucine zipper-mediated dimerization is essential for the PTC1 oncogenic activity. J Biol Chem
1997 · External reference
The RET proto-oncogene in human cancers. Oncogene
2000 · External reference
Large-scale characterization of HeLa cell nuclear phosphoproteins. Proc Natl Acad Sci USA
2004 · External reference
Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry Anal Chem
2004 · External reference
H4(D10S170), a gene frequently rearranged with RET in papillary thyroid carcinomas: functional characterization
10.1038/sj.onc.1206981 · 2004 · External reference
Involvement of H4(D10S170) protein in ATM-dependent response to DNA damage. Oncogene
2007 · External reference
10.1371/journal.pone.0036177
10.1371/journal.pone.0036177 · External reference
CCDC6 represses CREB1 activity by recruiting histone deacetylase 1 and protein phosphatase 1. Oncogene
2010 · External reference
Concepts in sumoylation: a decade on. Nat Rev Mol Cell Biol
2007 · External reference
SUMO and ubiquitin in the nucleus: different functions, similar mechanisms? Genes Dev
2004 · External reference
SUMO: a history of modification
2005 · External reference
Protein modification by SUMO. Annu Rev Biochem
2004 · External reference
Distinct in vivo dynamics of vertebrate SUMO paralogues. Mol Biol Cell
2004 · External reference
Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3 J Biol Chem
2000 · External reference
Distinct and overlapping sets of SUMO-1 and SUMO-2 target proteins revealed by quantitative proteomics. Mol Cell Proteomics
2006 · External reference
Post-translational modification by the small ubiquitin-related modifier SUMO has big effects on transcription factor activity Curr Opin Genet Dev
2003 · External reference
SUMO and transcriptional regulation Semin Cell Dev Biol
2004 · External reference
Regulation of the Ets-1 transcription factor by sumoylation and ubiquitinylation
10.1038/sj.onc.1209789 · 2007 · External reference
Unresolved reference
External reference
One- and two-step transformations of rat thyroid epithelial cells by retroviral oncogenes. Mol Cell Biol
1987 · External reference
Cooperation between the polyomavirus middle-T-antigen gene and the human c-myc oncogene in a rat thyroid epithelial differentiated cell line: model of in vitro progression. Mol Cell Biol
1988 · External reference
Description of a human papillary thyroid carcinoma cell line. Morphologic study and expression of tumoral markers
10.1002/1097-0142(19940415)73:8<2206::aid-cncr2820730828>3.0.co;2-m · 1994 · External reference
A proteomic study of SUMO-2 target proteins. J Biol Chem
2004 · External reference
SUMO modification of the Ets-related transcription factor ERM inhibits its transcriptional activity. J Biol Chem
2005 · External reference
Imaging fluorescence resonance energy transfer as probe of membrane organization and molecular associations of GPI-anchored proteins. Methods Mol Biol
1999 · External reference
High Mobility Group A1 (HMGA1) proteins interact with p53 and inhibit its apoptotic activity. Cell Death Differ
2006 · External reference
HMGA proteins up-regulate CCNB2 gene in mouse and human pituitary adenomas Cancer Res
2009 · External reference
Functional interaction of the subunit 3 of RNA polymerase II (RPB3) with transcription factor-4 (ATF4). FEBS Lett
2003 · External reference
Amphiregulin: a new growth factor in hepatocarcinogenesis. Cancer Lett
2007 · External reference
Small ubiquitin-related modifier-1 modification mediates resolution of CREB-dependent responses to hypoxia. Proc Natl Acad Sci U S A
2003 · External reference
Daxx mediates SUMO-dependent transcriptional control and subnuclear compartmentalization. Biochem Soc Trans
2007 · External reference
Selective SUMO modification of cAMP-specific phosphodiesterase-4D5 (PDE4D5) regulates the functional consequences of phosphorylation by PKA and ERK. Biochem J
2010 · External reference
SENP1 enhances androgen receptor-dependent transcription through desumoylation of histone deacetylase 1. Mol Cell Biol
2004 · External reference
SUMO association with repressor complexes, emerging routes for transcriptional control. Biochim Biophys Acta
2009 · External reference
Analysis of in vitro SUMOylation using bioluminescence resonance energy transfer (BRET). Biochem Biophys Res Commun
2009 · External reference
Quantitative analysis of multi-protein interactions using FRET: application to the SUMO pathway
10.1110/ps.073369608 · 2008 · External reference
SUMO protein modification. Biochim Biophys Acta
2004 · External reference
10.1038/nrm1200
10.1038/nrm1200 · External reference
Regulation of thyroid cell proliferation by TSH and other factors: acritical evaluation of in vitro models. Endocr Rev
2001 · External reference
CREB a real culprit in oncogenesis FEBS Journal
2007 · External reference
SUMO: a regulator of gene expression and genome integrity. Oncogene
2004 · External reference
SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation
10.1016/s1097-2765(00)80133-1 · 1998 · External reference
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature
2002 · External reference
MAP Kinase: SUMO pathway interactions. Methods Mol Biol
2010 · External reference
Higher serum thyroid stimulating hormone level in thyroid nodule patients is associated with greater risks of differentiated thyroid cancer and advanced tumor stage
10.1210/jc.2007-2215 · 2008 · External reference
Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice. Proc Natl Acad Sci U S A
2011 · External reference
