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References from Direct Infection of Dendritic Cells during Chronic Viral Infection Suppresses Antiviral T Cell Proliferation and Induces IL-10 Expression in CD4 T Cells. Local targets link to admitted publications; unresolved targets remain external evidence.
IL-10, T cell exhaustion and viral persistence
10.1016/j.tim.2007.02.006 · 2007 · External reference
Hepatitis C virus non-structural protein 4 suppresses Th1 responses by stimulating IL-10 production from monocytes
10.1002/eji.200324251 · 2003 · External reference
Interleukin-10 determines viral clearance or persistence <italic>in vivo</italic>
10.1038/nm1492 · 2006 · External reference
Role of interleukin-10 in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus
10.1172/jci117031 · 1994 · External reference
Resolution of a chronic viral infection after interleukin-10 receptor blockade
10.1084/jem.20061462 · 2006 · External reference
Human cytomegalovirus harbors its own unique IL-10 homolog (cmvIL-10)
10.1073/pnas.97.4.1695 · 2000 · External reference
Murine cytomegalovirus infection down-regulates MHC class II expression on macrophages by induction of IL-10
10.4049/jimmunol.162.11.6701 · 1999 · External reference
Hijacking and exploitation of IL-10 by intracellular pathogens
10.1016/s0966-842x(00)01919-3 · 2001 · External reference
The regulation of IL-10 production by immune cells
10.1038/nri2711 · 2010 · External reference
Viral immune evasion due to persistence of activated T cells without effector function
10.1084/jem.188.12.2205 · 1998 · External reference
Molecular signature of CD8+ T cell exhaustion during chronic viral infection
10.1016/j.immuni.2007.09.006 · 2007 · External reference
T cell exhaustion
10.1038/ni.2035 · 2011 · External reference
Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes
10.1084/jem.187.9.1383 · 1998 · External reference
Immunosuppression and resultant viral persistence by specific viral targeting of dendritic cells
10.1084/jem.192.9.1249 · 2000 · External reference
Viral targeting of hematopoietic progenitors and inhibition of DC maturation as a dual strategy for immune subversion
10.1172/jci20243 · 2004 · External reference
Persistent virus infection inhibits type I interferon production by plasmacytoid dendritic cells to facilitate opportunistic infections
10.1016/j.chom.2008.08.016 · 2008 · External reference
Genetic basis of viral persistence: single amino acid change in the viral glycoprotein affects ability of lymphocytic choriomeningitis virus to persist in adult mice
10.1084/jem.172.4.1043 · 1990 · External reference
Molecular basis of viral persistence: a single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with suppression of the antiviral cytotoxic T-lymphocyte response and establishment of persistence
10.1128/jvi.65.4.1863-1869.1991 · 1991 · External reference
Virus-lymphocyte interactions. IV. Molecular characterization of LCMV Armstrong (CTL+) small genomic segment and that of its variant, Clone 13 (CTL-)
10.1016/0042-6822(88)90566-1 · 1988 · External reference
Point mutation in the glycoprotein of lymphocytic choriomeningitis virus is necessary for receptor binding, dendritic cell infection, and long-term persistence
10.1073/pnas.1019304108 · 2011 · External reference
Emergence of distinct multiarmed immunoregulatory antigen-presenting cells during persistent viral infection
10.1016/j.chom.2012.03.009 · 2012 · External reference
Infected CD8alpha- dendritic cells are the predominant source of IL-10 during establishment of persistent viral infection
10.1073/pnas.1211910109 · 2012 · External reference
Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knockin tiger mouse
10.1016/j.immuni.2006.09.013 · 2006 · External reference
Characterization of lymphocytic choriomeningitis virus-binding protein(s): a candidate cellular receptor for the virus
10.1128/jvi.66.12.7270-7281.1992 · 1992 · External reference
Lymphocytic choriomeningitis virus. X. Demonstration of nucleoprotein on the surface of infected cells
10.1016/0042-6822(88)90397-2 · 1988 · External reference
CD8alpha+ dendritic cells selectively present MHC class I-restricted noncytolytic viral and intracellular bacterial antigens <italic>in vivo</italic>
10.4049/jimmunol.175.1.196 · 2005 · External reference
Virus-specific MHC-class II-restricted TCR-transgenic mice: effects on humoral and cellular immune responses after viral infection
10.1002/(sici)1521-4141(199801)28:01<390::aid-immu390>3.0.co;2-o · 1998 · External reference
Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
10.1038/32183 · 1998 · External reference
Constitutive versus activation-dependent cross-presentation of immune complexes by CD8(+) and CD8(−) dendritic cells <italic>in vivo</italic>
10.1084/jem.20020295 · 2002 · External reference
Promiscuous binding of extracellular peptides to cell surface class I MHC protein
10.1073/pnas.1201586109 · 2012 · External reference
Pathways of antigen processing
10.1146/annurev-immunol-032712-095910 · 2013 · External reference
Cross-presentation in viral immunity and self-tolerance
10.1038/35100512 · 2001 · External reference
Cross-presentation by dendritic cells
10.1038/nri3254 · 2012 · External reference
The outcome of cross-priming during virus infection is not directly linked to the ability of the antigen to be cross-presented
10.1002/eji.200939973 · 2010 · External reference
Cross-presentation of the long-lived lymphocytic choriomeningitis virus nucleoprotein does not require neosynthesis and is enhanced via heat shock proteins
10.4049/jimmunol.175.2.796 · 2005 · External reference
A lymphocytic choriomeningitis virus glycoprotein variant that is retained in the endoplasmic reticulum efficiently cross-primes CD8(+) T cell responses
10.1073/pnas.0704423104 · 2007 · External reference
CTL induction by cross-priming is restricted to immunodominant epitopes
10.1002/eji.200838901 · 2009 · External reference
MHC class I cross-presentation by dendritic cells counteracts viral immune evasion
10.3389/fimmu.2012.00348 · 2012 · External reference
Mechanisms of viral interference with MHC class I antigen processing and presentation
10.1146/annurev.cellbio.15.1.579 · 1999 · External reference
Viral interference with antigen presentation
10.1038/ni1102-1019 · 2002 · External reference
Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
10.1038/342559a0 · 1989 · External reference
Macrophage and T cell produced IL-10 promotes viral chronicity
10.1371/journal.ppat.1003735 · 2013 · External reference
Quantitative PCR technique for detecting lymphocytic choriomeningitis virus <italic>in vivo</italic>
10.1016/j.jviromet.2007.08.025 · 2008 · External reference
