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References from Comparison of conventional, amplification and bio-assay detection methods for a chronic wasting disease inoculum pool. Local targets link to admitted publications; unresolved targets remain external evidence.
Environmental sources of prion transmission in mule deer
10.3201/eid1006.040010 · 2004 · External reference
Infectious prions in pre-clinical deer and transmission of chronic wasting disease solely by environmental exposure
10.1371/journal.pone.0005916 · 2009 · External reference
Infectious prions in the saliva and blood of deer with chronic wasting disease
10.1126/science.1132661 · 2006 · External reference
Transmission and detection of prions in feces
10.1086/588193 · 2008 · External reference
Detection of sub-clinical CWD infection in conventional test-negative deer long after oral exposure to urine and feces from CWD+ deer
10.1371/journal.pone.0007990 · 2009 · External reference
Infectious Prions in the Pregnancy Microenvironment of CWD-infected Reeves' Muntjac Deer
2017 · External reference
Unresolved reference
External reference
A case of chronic wasting disease in an elk imported to Korea from Canada
10.1292/jvms.64.855 · 2002 · External reference
First case of chronic wasting disease in Europe in a Norwegian free-ranging reindeer
10.1186/s13567-016-0375-4 · 2016 · External reference
Chronic wasting disease: an evolving prion disease of cervids.
10.1016/b978-0-444-63945-5.00008-8 · 2018 · External reference
Evidence for distinct chronic wasting disease (CWD) strains in experimental CWD in ferrets
10.1099/vir.0.035006-0 · 2012 · External reference
Prion strain mutation determined by prion protein conformational compatibility and primary structure
10.1126/science.1187107 · 2010 · External reference
The Priority position paper: Protecting Europe's food chain from prions
10.1080/19336896.2016.1175801 · 2016 · External reference
Pathogen-mediated selection in free-ranging elk populations infected by chronic wasting disease
10.1073/pnas.1707807114 · 2017 · External reference
Prion protein polymorphisms in white-tailed deer influence susceptibility to chronic wasting disease
10.1099/vir.0.81615-0 · 2006 · External reference
Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent
10.1038/39057 · 1997 · External reference
Identification of a protein that purifies with the scrapie prion
10.1126/science.6815801 · 1982 · External reference
Evolution of Diagnostic Tests for Chronic Wasting Disease, a Naturally Occurring Prion Disease of Cervids
10.3390/pathogens6030035 · 2017 · External reference
Prion disease blood test using immunoprecipitation and improved quaking-induced conversion
2011 · External reference
In vitro detection of prionemia in TSE-infected cervids and hamsters
10.1371/journal.pone.0080203 · 2013 · External reference
Real-time Quaking-induced Conversion Assay for Detection of CWD Prions in Fecal Material
10.3791/56373 · 2017 · External reference
Prions, proteinase K and infectivity
10.4161/pri.22309 · 2012 · External reference
Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding
10.1038/35081095 · 2001 · External reference
Prion detection by an amyloid seeding assay
10.1073/pnas.0710152105 · 2007 · External reference
Protein Misfolding Cyclic Amplification of Infectious Prions.
10.1016/bs.pmbts.2017.06.016 · 2017 · External reference
Ultrasensitive detection of scrapie prion protein using seeded conversion of recombinant prion protein
10.1038/nmeth1066 · 2007 · External reference
Rapid end-point quantitation of prion seeding activity with sensitivity comparable to bioassays
10.1371/journal.ppat.1001217 · 2010 · External reference
High diagnostic value of second generation CSF RT-QuIC across the wide spectrum of CJD prions
10.1038/s41598-017-10922-w · 2017 · External reference
Pathways of Prion Spread during Early Chronic Wasting Disease in Deer
2017 · External reference
Rapid and ultra-sensitive quantitation of disease-associated alpha-synuclein seeds in brain and cerebrospinal fluid by alphaSyn RT-QuIC
10.1186/s40478-018-0508-2 · 2018 · External reference
Diagnostic and prognostic value of human prion detection in cerebrospinal fluid
10.1002/ana.24833 · 2017 · External reference
Familial human prion diseases associated with prion protein mutations Y226X and G131V are transmissible to transgenic mice expressing human prion protein
10.1186/s40478-018-0516-2 · 2018 · External reference
Cerebrospinal fluid real-time quaking-induced conversion test for sporadic Creutzfeldt-Jakob disease in an 18-year-old woman: A case report
10.1097/md.0000000000008699 · 2017 · External reference
Prion seeding activity and infectivity in skin samples from patients with sporadic Creutzfeldt-Jakob disease
2017 · External reference
Enhanced prion detection in biological samples by magnetic particle extraction and real-time quaking-induced conversion
10.1099/jgv.0.000515 · 2016 · External reference
Detection and Quantification of CWD Prions in Fixed Paraffin Embedded Tissues by Real-Time Quaking-Induced Conversion
10.1038/srep25098 · 2016 · External reference
Rapid and sensitive RT-QuIC detection of human Creutzfeldt-Jakob disease using cerebrospinal fluid
2015 · External reference
Rapid antemortem detection of CWD prions in deer saliva
10.1371/journal.pone.0074377 · 2013 · External reference
Early detection of chronic wasting disease prions in urine of pre-symptomatic deer by real-time quaking-induced conversion assay
10.4161/pri.24430 · 2013 · External reference
Immediate and Ongoing Detection of Prions in the Blood of Hamsters and Deer following Oral, Nasal, or Blood Inoculations
10.1128/jvi.00760-15 · 2015 · External reference
Quantitative assessment of prion infectivity in tissues and body fluids by real-time quaking-induced conversion
10.1099/vir.0.069906-0 · 2015 · External reference
Real-Time Quaking-Induced Conversion Detection of Bovine Spongiform Encephalopathy Prions in a Subclinical Steer.
10.3389/fvets.2017.00242 · 2017 · External reference
Detection of Prions in Blood of Cervids at the Asymptomatic Stage of Chronic Wasting Disease.
10.1038/s41598-017-17090-x · 2017 · External reference
Distribution and Quantitative Estimates of Variant Creutzfeldt-Jakob Disease Prions in Tissues of Clinical and Asymptomatic Patients
10.3201/eid2306.161734 · 2017 · External reference
Detection of prions in the plasma of presymptomatic and symptomatic patients with variant Creutzfeldt-Jakob disease
10.1126/scitranslmed.aag1257 · 2016 · External reference
New insight into abnormal prion protein using monoclonal antibodies
10.1006/bbrc.1999.1730 · 1999 · External reference
The first Canadian indigenous case of bovine spongiform encephalopathy (BSE) has molecular characteristics for prion protein that are similar to those of BSE in the United Kingdom but differ from those of chronic wasting disease in captive elk and deer
2004 · External reference
Distribution of protease-resistant prion protein and spongiform encephalopathy in free-ranging mule deer (Odocoileus hemionus) with chronic wasting disease
10.1354/vp.39-5-546 · 2002 · External reference
Immunohistochemical detection of prion protein in sheep with scrapie
10.1177/104063879300500301 · 1993 · External reference
Ante-mortem detection of chronic wasting disease in recto-anal mucosa-associated lymphoid tissues from elk (Cervus elaphus nelsoni) using real-time quaking-induced conversion (RT-QuIC) assay: A blinded collaborative study
10.1080/19336896.2017.1368936 · 2017 · External reference
Detection of CWD prions in urine and saliva of deer by transgenic mouse bioassay
10.1371/journal.pone.0004848 · 2009 · External reference
Modified Protein Misfolding Cyclic Amplification Overcomes Real-Time Quaking-Induced Conversion Assay Inhibitors in Deer Saliva To Detect Chronic Wasting Disease Prions
10.1128/jcm.00947-18 · 2018 · External reference
Detection and Quantification of CWD Prions in Fixed Paraffin Embedded Tissues by Real-Time Quaking-Induced Conversion
10.1038/srep25098 · 2016 · External reference
New generation QuIC assays for prion seeding activity
10.4161/pri.19430 · 2012 · External reference
Pathogenesis, virulence, and infective dose
10.1371/journal.ppat.0030147 · 2007 · External reference
The Role of Unfolded Protein Response and Mitogen-Activated Protein Kinase Signaling in Neurodegenerative Diseases with Special Focus on Prion Diseases.
10.3389/fnagi.2017.00120 · 2017 · External reference
The role of endoplasmic reticulum stress in neurodegenerative disease
10.1007/s10495-016-1296-4 · 2017 · External reference
The most infectious prion protein particles
10.1038/nature03989 · 2005 · External reference
Prion-seeding activity in cerebrospinal fluid of deer with chronic wasting disease.
10.1371/journal.pone.0081488 · 2013 · External reference
Spongiform encephalopathy in free-ranging mule deer (Odocoileus hemionus), white-tailed deer (Odocoileus virginianus) and Rocky Mountain elk (Cervus elaphus nelsoni) in northcentral Colorado
10.7589/0090-3558-33.1.1 · 1997 · External reference
Evaluation of two sets of immunohistochemical and Western blot confirmatory methods in the detection of typical and atypical BSE cases
10.1186/1756-0500-4-376 · 2011 · External reference
Tissue distribution of protease resistant prion protein in variant Creutzfeldt-Jakob disease using a highly sensitive immunoblotting assay
10.1016/s0140-6736(01)05403-4 · 2001 · External reference
Western blot mapping of disease-specific amyloid in various animal species and humans with transmissible spongiform encephalopathies using a high-yield purification method
10.1099/0022-1317-76-10-2567 · 1995 · External reference
Detection of scrapie-associated fibril (SAF) proteins using anti-SAF antibody in non-purified tissue preparations
10.1099/0022-1317-67-4-671 · 1986 · External reference
Antemortem detection of PrPCWD in preclinical, ranch-raised Rocky Mountain elk (Cervus elaphus nelsoni) by biopsy of the rectal mucosa
10.1177/104063870902100103 · 2009 · External reference
Prevalent abnormal prion protein in human appendixes after bovine spongiform encephalopathy epizootic: large scale survey
10.1136/bmj.f5675 · 2013 · External reference
deposition in nervous tissues without lymphoid tissue involvement is frequently found in ARQ/ARQ Sarda breed sheep preclinically affected with natural scrapie
10.1007/s00705-006-0759-2 · 2006 · External reference
Biochemical Characterization of Prions.
10.1016/bs.pmbts.2017.06.012 · 2017 · External reference
Time course of prion seeding activity in cerebrospinal fluid of scrapie-infected hamsters after intratongue and intracerebral inoculations
10.1128/jcm.06099-11 · 2012 · External reference
Prion and prion-like diseases in animals
10.1016/j.virusres.2014.11.026 · 2015 · External reference
In utero transmission and tissue distribution of chronic wasting disease-associated prions in free-ranging Rocky Mountain elk
2015 · External reference
Mother to offspring transmission of chronic wasting disease in reeves' muntjac deer.
10.1371/journal.pone.0071844 · 2013 · External reference
Detection of PrP(BSE) and prion infectivity in the ileal Peyer's patch of young calves as early as 2 months after oral challenge with classical bovine spongiform encephalopathy
10.1186/s13567-017-0495-5 · 2017 · External reference
Experimental Transmission of the Chronic Wasting Disease Agent to Swine after Oral or Intracranial Inoculation
10.1128/jvi.00926-17 · 2017 · External reference
An assessment of the long-term persistence of prion infectivity in aquatic environments
10.1016/j.envres.2016.08.031 · 2016 · External reference
Evidence of scrapie transmission to sheep via goat milk
10.1186/s12917-016-0807-4 · 2016 · External reference
Transmission of scrapie prions to primate after an extended silent incubation period.
10.1038/srep11573 · 2015 · External reference
Transmission of prion diseases by blood transfusion
10.1099/0022-1317-83-11-2897 · 2002 · External reference
Ultra-efficient replication of infectious prions by automated protein misfolding cyclic amplification
10.1074/jbc.m603964200 · 2006 · External reference
Mammalian prions and their wider relevance in neurodegenerative diseases
10.1038/nature20415 · 2016 · External reference
Protein misfolding, aggregation, and conformational strains in neurodegenerative diseases
10.1038/s41593-018-0235-9 · 2018 · External reference
Detection of misfolded Abeta oligomers for sensitive biochemical diagnosis of Alzheimer's disease
10.1016/j.celrep.2014.02.031 · 2014 · External reference
Development of a Biochemical Diagnosis of Parkinson Disease by Detection of alpha-Synuclein Misfolded Aggregates in Cerebrospinal Fluid.
10.1001/jamaneurol.2016.4547 · 2017 · External reference
Detection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia
10.1038/srep46269 · 2017 · External reference
Potential biomarkers and novel pharmacological targets in protein aggregation-related neurodegenerative diseases
10.1016/j.bcp.2017.01.017 · 2017 · External reference
Aerosol transmission of chronic wasting disease in white-tailed deer
10.1128/jvi.02852-12 · 2013 · External reference
Mucosal immunization with an attenuated Salmonella vaccine partially protects white-tailed deer from chronic wasting disease
10.1016/j.vaccine.2014.11.035 · 2015 · External reference
Transmission of prions from mule deer and elk with chronic wasting disease to transgenic mice expressing cervid PrP
10.1128/jvi.78.23.13345-13350.2004 · 2004 · External reference