Research graph
References from In silico analyses identify lncRNAs: WDFY3-AS2, BDNF-AS and AFAP1-AS1 as potential prognostic factors for patients with triple-negative breast tumors. Local targets link to admitted publications; unresolved targets remain external evidence.
Global Cancer Statistics 2018: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
2018 · External reference
Biomarker research in breast cancer
10.1188/10.cjon.771-783 · 2010 · External reference
Molecular diagnostic testing in breast cancer
10.1016/j.soncn.2015.02.008 · 2015 · External reference
Molecular Stratification of Triple-Negative Breast Cancers
10.1634/theoncologist.2011-s1-61 · 2011 · External reference
Molecular portraits of human breast tumours
10.1038/35021093 · 2000 · External reference
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
10.1073/pnas.191367098 · 2001 · External reference
Triple negative breast cancer subtypes and pathologic complete response rate to neoadjuvant chemotherapy
2018 · External reference
Refinement of Triple-Negative Breast Cancer Molecular Subtypes: Implications for Neoadjuvant Chemotherapy Selection
10.1371/journal.pone.0157368 · 2016 · External reference
Potential Management of Circulating Tumor DNA as a Biomarker in Triple-Negative Breast Cancer
2018 · External reference
The clinical promise of immunotherapy in triple-negative breast cancer
2018 · External reference
Advances in the systemic treatment of triple-negative breast cancer
10.3747/co.25.3954 · 2018 · External reference
Triple-negative breast cancer: Treatment challenges and solutions
2016 · External reference
Molecular Mechanisms and Emerging Therapeutic Targets of Triple-Negative Breast Cancer Metastasis
10.3389/fonc.2018.00031 · 2018 · External reference
Downregulation of Long Noncoding RNA HOTAIR and EZH2 Induces Apoptosis and Inhibits Proliferation, Invasion, and Migration of Human Breast Cancer Cells
2018 · External reference
Identification of long non-coding RNA signatures in triple-negative breast cancer
10.1186/s12935-018-0598-8 · 2018 · External reference
Long noncoding RNA FOXD2-AS1 promotes glioma cell cycle progression and proliferation through the FOXD2-AS1/miR-31/CDK1 pathway
2019 · External reference
Long non-coding RNA ANRIL promotes carcinogenesis via sponging miR-199a in triple-negative breast cancer
10.1016/j.biopha.2017.09.107 · 2017 · External reference
Long noncoding RNA BDNF-AS is downregulated in cervical cancer and has anti-cancer functions by negatively associating with BDNF
10.1016/j.abb.2018.03.023 · 2018 · External reference
Long noncoding RNA CASC2 promotes paclitaxel resistance in breast cancer through regulation of miR-18a-5p/CDK19
2019 · External reference
Deciphering the roles of lncRNAs in breast development and disease
10.18632/oncotarget.24591 · 2018 · External reference
Exploring the mechanisms behind long noncoding RNAs and cancer
10.1016/j.ncrna.2018.03.001 · 2018 · External reference
The functions and unique features of long intergenic non-coding RNA
10.1038/nrm.2017.104 · 2018 · External reference
Non-coding RNAs as potential therapeutic targets in breast cancer
2019 · External reference
Long non-coding RNAs: Functional regulatory players in breast cancer
10.1016/j.ncrna.2019.01.003 · 2019 · External reference
Comprehensive Analysis of Differentially Expressed Profiles of lncRNAs/mRNAs and miRNAs with Associated ceRNA Networks in Triple-Negative Breast Cancer
10.1159/000494162 · 2018 · External reference
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
10.1038/nature08975 · 2010 · External reference
Long non-coding RNA DRHC inhibits the proliferation of cancer cells in triple negative breast cancer by downregulating long non-coding RNA HOTAIR
2019 · External reference
Overexpression of MiR-146a-5p Upregulates lncRNA HOTAIR in Triple-Negative Breast Cancer Cells and Predicts Poor Prognosis
2019 · External reference
HOTAIR overexpression correlated with worse survival in patients with solid tumors
2016 · External reference
Circulating HOTAIR expression predicts the clinical response to neoadjuvant chemotherapy in patients with breast cancer
10.3233/cbm-170874 · 2018 · External reference
Long noncoding RNA H19 mediated the chemosensitivity of breast cancer cells via wnt pathway and EMT process
10.2147/ott.s172379 · 2018 · External reference
MEG3 is a prognostic factor for CRC and promotes chemosensitivity by enhancing oxaliplatin-induced cell apoptosis
10.3892/or.2017.5828 · 2017 · External reference
Up-regulated lncRNA GAS5 promotes chemosensitivity and apoptosis of triple-negative breast cancer cells. Cell Cycle
2019 · External reference
MALAT1 is a prognostic factor in glioblastoma multiforme and induces chemoresistance to temozolomide through suppressing miR-203 and promoting thymidylate synthase expression
2017 · External reference
Long Non-Coding RNA and Breast Cancer
2019 · External reference
Association of SPARC gene polymorphisms rs3210714 and rs7719521 with VEGF expression and utility of Nottingham Prognostic Index scoring in breast cancer in a sample of Egyptian women
10.1007/s11033-018-4394-2 · 2018 · External reference
SPARC inhibits breast cancer bone metastasis and may be a clinical therapeutic target
2017 · External reference
SPARC: A matricellular regulator of tumorigenesis
10.1007/s12079-009-0072-4 · 2009 · External reference
Transcriptome characterization of human mammary cell lines expressing different levels of ERBB2 by serial analysis of gene expression
2006 · External reference
Transcriptome changes induced by docetaxel in human mammary cell lines expressing different levels of ERBB2
2009 · External reference
Prognostic value of NDRG1 and SPARC protein expression in breast cancer patients
10.1007/s10549-010-0867-2 · 2011 · External reference
Gene expression profiling of triple-negative breast tumors with different expression of secreted protein acidic and cysteine rich (SPARC)
10.2217/bmt-2017-0019 · 2018 · External reference
An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients
2010 · External reference
TANRIC: An interactive open platform to explore the function of IncRNAs in cancer
2015 · External reference
The UCSC Xena platform for public and private cancer genomics data visualization and interpretation
2019 · External reference
Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal
2013 · External reference
The cBio Cancer Genomics Portal: An open platform for exploring multidimensional cancer genomics data
10.1158/2159-8290.cd-12-0095 · 2012 · External reference
UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses
2017 · External reference
STRING v11: Protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
2019 · External reference
Differential Analysis of lncRNA, miRNA and mRNA Expression Profiles and the Prognostic Value of lncRNA in Esophageal Cancer
2019 · External reference
Expression profile analysis of antisense long non-coding RNA identifies WDFY3-AS2 as a prognostic biomarker in diffuse glioma
10.1186/s12935-018-0603-2 · 2018 · External reference
Identification of lnc RNA s associated with early-stage breast cancer and their prognostic implications
10.1002/1878-0261.12489 · 2019 · External reference
EMT-related long non-coding RNA in hepatocellular carcinoma: A study with TCGA database
10.1016/j.bbrc.2018.07.075 · 2018 · External reference
Long noncoding RNA WDFY3-AS2 suppresses tumor progression by acting as a competing endogenous RNA of microRNA-18a in ovarian cancer
2019 · External reference
LncRNA BDNF-AS is associated with the malignant status and regulates cell proliferation and apoptosis in osteosarcoma
10.1042/bsr20181498 · 2018 · External reference
Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation
10.1038/nbt.2158 · 2012 · External reference
LncRNA BDNF-AS suppresses colorectal cancer cell proliferation and migration by epigenetically repressing GSK-3β expression
2019 · External reference
Long noncoding RNA BDNF-AS is associated with clinical outcomes and has functional role in human prostate cancer
10.1016/j.biopha.2018.03.118 · 2018 · External reference
Expression analysis of AFAP1-AS1 and AFAP1 in breast cancer
10.3233/cbm-170831 · 2018 · External reference
AFAP1-AS1 Promotes Epithelial-Mesenchymal Transition and Tumorigenesis Through Wnt/β-Catenin Signaling Pathway in Triple-Negative Breast Cancer
10.3389/fphar.2018.01248 · 2018 · External reference
