Research graph
References from The synthetic opioid fentanyl increases HIV replication in macrophages. Local targets link to admitted publications; unresolved targets remain external evidence.
Trends in US drug overdose deaths in non-Hispanic black, Hispanic, and non-Hispanic white persons, 2000–2015
10.7326/m17-1812 · 2018 · External reference
Changing dynamics of the drug overdose epidemic in the United States from 1979 through 2016
10.1126/science.aau1184 · 2018 · External reference
The opioid crisis and HIV in the USA: deadly synergies
10.1016/s0140-6736(21)00391-3 · 2021 · External reference
The fentanyl story
10.1016/j.jpain.2014.08.010 · 2014 · External reference
Naloxone for heroin, prescription opioid, and illicitly made fentanyl overdoses: challenges and innovations responding to a dynamic epidemic
10.1016/j.drugpo.2017.06.005 · 2017 · External reference
Unresolved reference
External reference
Mental health services administration
2013 · External reference
Trends and patterns of geographic variation in mortality from substance use disorders and intentional injuries among US counties, 1980–2014
10.1001/jama.2018.0900 · 2018 · External reference
Threading the needle—how to stop the HIV outbreak in rural Indiana
10.1056/nejmp1507252 · 2015 · External reference
Community outbreak of HIV infection linked to injection drug use of oxymorphone—Indiana, 2015
2015 · External reference
Opiates as potential cofactors in progression of HIV-1 infections to AIDS
10.1016/s0165-5728(97)00224-5 · 1998 · External reference
Opioid modulation of immune responses: effects on phagocyte and lymphoid cell populations
10.1016/s0165-5728(97)00219-1 · 1998 · External reference
Opiates transdeactivate chemokine receptors: δ and μ opiate receptor–mediated heterologous desensitization
10.1084/jem.188.2.317 · 1998 · External reference
Morphine promotes the growth of HIV-1 in human peripheral blood mononuclear cell cocultures
10.1097/00002030-199009000-00006 · 1990 · External reference
Opioid drug abuse and modulation of immune function: consequences in the susceptibility to opportunistic infections
10.1007/s11481-011-9292-5 · 2011 · External reference
Opioids and the immune system–friend or foe
10.1111/bph.13750 · 2018 · External reference
HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
10.1038/nm.1972 · 2009 · External reference
The role of macrophages in HIV-1 persistence and pathogenesis
10.3389/fmicb.2019.02828 · 2019 · External reference
HIV infection stabilizes macrophage-T cell interactions to promote cell-cell HIV spread
10.1128/jvi.00805-19 · 2019 · External reference
Pathophysiology of CD4+ T-cell depletion in HIV-1 and HIV-2 infections
10.3389/fimmu.2017.00580 · 2017 · External reference
The Synthetic Opioid Fentanyl Increases HIV Replication and Chemokine Co-Receptor Expression in Lymphocyte Cell Lines
10.3390/v15041027 · 2023 · External reference
Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
10.1128/jvi.59.2.284-291.1986 · 1986 · External reference
Quantitative detection of human immunodeficiency virus type 1 (HIV-1) proviral DNA in peripheral blood mononuclear cells by SYBR green real-time PCR technique
10.1016/s1386-6532(03)00169-0 · 2004 · External reference
Balancing yield, purity and practicality: a modified differential ultracentrifugation protocol for efficient isolation of small extracellular vesicles from human serum
10.1080/15476286.2018.1564465 · 2019 · External reference
Fast gapped-read alignment with Bowtie 2
10.1038/nmeth.1923 · 2012 · External reference
Orchestrating high-throughput genomic analysis with Bioconductor
10.1038/nmeth.3252 · 2015 · External reference
miRBase: annotating high confidence microRNAs using deep sequencing data
10.1093/nar/gkt1181 · 2014 · External reference
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
10.1093/bioinformatics/btp616 · 2010 · External reference
Intracerebral hemorrhage induces inflammatory gene expression in peripheral blood: global transcriptional profiling in intracerebral hemorrhage patients
10.1089/dna.2018.4550 · 2019 · External reference
Varying negative pressure wound therapy acute effects on human split-thickness autografts
2020 · External reference
Linear models and empirical bayes methods for assessing differential expression in microarray experiments
10.2202/1544-6115.1027 · 2004 · External reference
Morphine suppresses IFN signaling pathway and enhances AIDS virus infection
10.1371/journal.pone.0031167 · 2012 · External reference
Methadone enhances human immunodeficiency virus infection of human immune cells
10.1086/338011 · 2002 · External reference
Methadone inhibits viral restriction factors and facilitates HIV infection in macrophages
10.3389/fimmu.2020.01253 · 2020 · External reference
The synthetic opioid fentanyl enhances viral replication in vitro
10.1371/journal.pone.0249581 · 2021 · External reference
Opiate use inhibits TLR9 signaling pathway in vivo: possible role in pathogenesis of HIV-1 infection
10.1038/s41598-017-12066-3 · 2017 · External reference
The synthetic opioid fentanyl increases HIV replication and chemokine co-receptor expression in vitro
10.1007/s13365-022-01090-3 · 2022 · External reference
Analysis of evidence for the combination of pro-dopamine regulator (KB220PAM) and naltrexone to prevent opioid use disorder relapse
2018 · External reference
Opioids, opioid receptors, and the immune response
10.1016/s0376-8716(00)00181-2 · 2001 · External reference
Morphine enhances HIV infection of human blood mononuclear phagocytes through modulation of β-chemokines and CCR5 receptor
10.1136/jim-50-06-03 · 2002 · External reference
Morphine enhances HIV infection of neonatal macrophages
10.1203/01.pdr.0000074973.83826.4c · 2003 · External reference
μ-opioid modulation of HIV-1 coreceptor expression and HIV-1 replication
10.1016/s0042-6822(03)00015-1 · 2003 · External reference
Upregulation of the δ opioid receptor in liver cancer promotes liver cancer progression both in vitro and in vivo
10.3892/ijo.2013.2046 · 2013 · External reference
Human immunodeficiency virus type 1 replication in peripheral blood mononuclear cells in the presence of cocaine
10.1093/infdis/168.5.1157 · 1993 · External reference
Cocaine potentiates HIV-1 replication in human peripheral blood mononuclear cell cocultures. Involvement of transforming growth factor-beta
10.4049/jimmunol.146.1.81 · 1991 · External reference
Effect of methamphetamine on expression of HIV coreceptors and CC-chemokines by dendritic cells
10.1016/j.lfs.2010.09.019 · 2011 · External reference
Methamphetamine enhances HIV-1 infectivity in monocyte derived dendritic cells
10.1007/s11481-008-9128-0 · 2009 · External reference
Implementing treatment of opioid-use disorder in rural settings: a focus on HIV and hepatitis C prevention and treatment
10.1007/s11904-018-0402-3 · 2018 · External reference
Associations between perceived illicit fentanyl use and infectious disease risks among people who inject drugs
10.1016/j.drugpo.2019.10.004 · 2019 · External reference
Recurrence of thoracic and labial herpes simplex virus infection in a patient receiving epidural fentanyl
1992 · External reference
Inhibition of anti-HIV microRNA expression: a mechanism for opioid-mediated enhancement of HIV infection of monocytes
10.1016/j.ajpath.2010.11.042 · 2011 · External reference
Cocaine modulates dendritic cell-specific C type intercellular adhesion molecule-3-grabbing nonintegrin expression by dendritic cells in HIV-1 patients
10.4049/jimmunol.174.11.6617 · 2005 · External reference
Involvement of the extracellular signal-regulated kinase cascade for cocaine-rewarding properties
10.1523/jneurosci.20-23-08701.2000 · 2000 · External reference
2002. Inhibition of morphine-potentiated HIV-1 replication in peripheral blood mononuclear cells with the nuclease-resistant 2-5A agonist analog, 2-5A (N6B)
10.1097/00042560-200205010-00002 · 1999 · External reference
Methadone induces CCR5 and promotes AIDS virus infection
10.1016/s0014-5793(02)02746-1 · 2002 · External reference
Medications for opioid use disorders: clinical and pharmacological considerations
10.1172/jci134708 · 2020 · External reference
2018. Extended-release naltrexone improves viral suppression among incarcerated persons living with HIV with opioid use disorders transitioning to the community: results of a double-blind, placebo-controlled randomized trial
10.1097/qai.0000000000001634 · 1999 · External reference
Methylnaltrexone antagonizes opioid-mediated enhancement of HIV infection of human blood mononuclear phagocytes
10.1124/jpet.103.056697 · 2003 · External reference
The role of toll-like receptors in retroviral infection
10.3390/microorganisms8111787 · 2020 · External reference
Polymorphisms in Toll-like receptor 9 influence the clinical course of HIV-1 infection
10.1097/qad.0b013e328012b8ac · 2007 · External reference
Contrasting roles for TLR ligands in HIV-1 pathogenesis
10.1371/journal.pone.0012831 · 2010 · External reference
Methamphetamine inhibits Toll-like receptor 9-mediated anti-HIV activity in macrophages
10.1089/aid.2012.0264 · 2013 · External reference
Metabolism of fentanyl and acetylfentanyl in human-induced pluripotent stem cell-derived hepatocytes
10.1248/bpb.b17-00709 · 2018 · External reference
Validation of the Neogen® fentanyl ELISA kit for blood and urine
2017 · External reference
Metabolic patterns of fentanyl, meperidine, methylphenidate, tapentadol and tramadol observed in urine, serum or plasma
2017 · External reference
Predicting opioid receptor binding affinity of pharmacologically unclassified designer substances using molecular docking
10.1371/journal.pone.0197734 · 2018 · External reference
Fentanyl family at the mu-opioid receptor: uniform assessment of binding and computational analysis
10.3390/molecules24040740 · 2019 · External reference
