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References from The N-linked glycosylation modifications in the hepatitis B surface protein impact cellular autophagy, HBV replication, and HBV secretion. Local targets link to admitted publications; unresolved targets remain external evidence.
Hepatitis B virus X protein inhibits autophagic degradation by impairing lysosomal maturation
10.4161/auto.27286 · 2014 · External reference
Global Patterns and Trends in Total Burden of Hepatitis B from 1990 to 2019 and Predictions to 2030
External reference
Hepatitis B virus DNA integration, chronic infections and hepatocellular carcinoma
10.3390/microorganisms9081787 · 2021 · External reference
A review of epidemiology and clinical relevance of Hepatitis B virus genotypes and subgenotypes
10.1016/j.clinre.2023.102180 · 2023 · External reference
Significance of viral status on occurrence of hepatitis B-related hepatocellular carcinoma
10.3748/wjg.v20.i20.5999 · 2014 · External reference
Novel HBV recombinants between genotypes B and C in 3’-terminal reverse transcriptase (RT) sequences are associated with enhanced viral DNA load, higher RT point mutation rates and place of birth among Chinese patients
10.1016/j.meegid.2017.10.023 · 2018 · External reference
Naturally occurring deletions/insertions in HBV core promoter tend to decrease in hepatitis B e antigen-positive chronic hepatitis B patients during antiviral therapy
10.3851/imp2955 · 2015 · External reference
Hepatitis B virus pre-S/S variants in liver diseases
10.3748/wjg.v24.i14.1507 · 2018 · External reference
Association of preS/S mutations with occult hepatitis B virus (HBV) infection in South Korea: transmission potential of distinct occult HBV variants
10.3390/ijms160613595 · 2015 · External reference
Key role of hepatitis B virus mutation in chronic hepatitis B development to hepatocellular carcinoma
10.4254/wjh.v7.i9.1282 · 2015 · External reference
Amino acid similarities and divergences in the small surface proteins of genotype C hepatitis B viruses between nucleos (t) ide analogue-naive and lamivudine-treated patients with chronic hepatitis B
10.1016/j.antiviral.2013.11.015 · 2014 · External reference
Characterization of potential antiviral resistance mutations in hepatitis B virus reverse transcriptase sequences in treatment-naive Chinese patients
10.1016/j.antiviral.2009.12.006 · 2010 · External reference
Envelope proteins of hepatitis B virus: molecular biology and involvement in carcinogenesis
10.3390/v13061124 · 2021 · External reference
Post-translational modification control of HBV biological processes
10.3389/fmicb.2018.02661 · 2018 · External reference
Posttranslational N-glycosylation of the hepatitis B virus large envelope protein
10.1186/1743-422x-4-45 · 2007 · External reference
Roles of N-linked glycans in the endoplasmic reticulum
10.1146/annurev.biochem.73.011303.073752 · 2004 · External reference
Drastic reduction in the production of subviral particles does not impair hepatitis B virus virion secretion
10.1128/jvi.00905-09 · 2009 · External reference
Impairment of hepatitis B virus virion secretion by single-amino-acid substitutions in the small envelope protein and rescue by a novel glycosylation site
10.1128/jvi.01499-10 · 2010 · External reference
Modification of the hepatitis B virus envelope protein glycosylation pattern interferes with secretion of viral particles, infectivity, and susceptibility to neutralizing antibodies
10.1128/jvi.01161-14 · 2014 · External reference
Biological significance of amino acid substitutions in hepatitis B surface antigen (HBsAg) for glycosylation, secretion, antigenicity and immunogenicity of HBsAg and hepatitis B virus replication
10.1099/vir.0.012740-0 · 2010 · External reference
N-glycosylation mutations within hepatitis B virus surface major hydrophilic region contribute mostly to immune escape
10.1016/j.jhep.2013.11.004 · 2014 · External reference
Naturally occurring hepatitis B virus mutations leading to endoplasmic reticulum stress and their contribution to the progression of hepatocellular carcinoma
10.3390/ijms20030597 · 2019 · External reference
The N-Glycosylation Modification of LHBs (Large Surface Proteins of HBV) Effects on Endoplasmic Reticulum Stress. Cell Proliferation and its Secretion
2013 · External reference
Autophagy: renovation of cells and tissues
10.1016/j.cell.2011.10.026 · 2011 · External reference
The early autophagic pathway is activated by hepatitis B virus and required for viral DNA replication
10.1073/pnas.0911373107 · 2010 · External reference
Hepatitis B virus X protein sensitizes cells to starvation-induced autophagy via up-regulation of beclin 1 expression
10.1002/hep.22581 · 2009 · External reference
Hepatitis B virus x protein induces autophagy via activating death-associated protein kinase
10.1111/jvh.12191 · 2014 · External reference
Autophagy required for hepatitis B virus replication in transgenic mice
10.1128/jvi.06064-11 · 2011 · External reference
Autophagy machinery impaired interferon signalling pathways to benefit hepatitis B virus replication
2016 · External reference
AMPK and Akt/mTOR signalling pathways participate in glucose-mediated regulation of hepatitis B virus replication and cellular autophagy
10.1111/cmi.13131 · 2020 · External reference
Astrocyte elevated gene-1 induces protective autophagy
10.1073/pnas.1009479107 · 2010 · External reference
Autophagy and apoptosis: where do they meet?
10.1007/s10495-014-0967-2 · 2014 · External reference
Regulation of hepatitis B virus replication by autophagic membranes
10.1080/15548627.2022.2117974 · 2023 · External reference
Subversion of cellular autophagy machinery by hepatitis B virus for viral envelopment
10.1128/jvi.02627-10 · 2011 · External reference
O-GlcNAcylation modulates HBV replication through regulating cellular autophagy at multiple levels
10.1096/fj.202001168rr · 2020 · External reference
Glycosylation in viral hepatitis
10.1016/j.bbagen.2021.129997 · 2021 · External reference
EASL clinical practice guidelines: management of hepatocellular carcinoma
10.1016/j.jhep.2018.03.019 · 2018 · External reference
The N-glycosylation modification of LHBs (large surface proteins of HBV) effects on endoplasmic reticulum stress, cell proliferation and its secretion
2013 · External reference
Hepatitis B virus surface gene pre-S2 mutant as a high-risk serum marker for hepatoma recurrence after curative hepatic resection
10.1002/hep.29790 · 2018 · External reference
Hepatitis B and C virus-related carcinogenesis
10.1111/j.1469-0691.2009.03035.x · 2009 · External reference
Hepatitis B virus X protein upregulates expression of SMYD3 and C-MYC in HepG2 cells
10.1007/s12032-008-9144-1 · 2009 · External reference
The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas
10.1016/s0002-9440(10)64996-6 · 2000 · External reference
Hepatitis B virus X protein increases expression of p21Cip-1/WAF1/MDA6 and p27Kip-1 in primary mouse hepatocytes, leading to reduced cell cycle progression
10.1053/jhep.2001.28886 · 2001 · External reference
The role of HBV-induced autophagy in HBV replication and HBV related-HCC
10.1016/j.lfs.2018.04.051 · 2018 · External reference
Apoptosis: a mechanism of acute and chronic liver injury
10.1136/gut.2004.053850 · 2005 · External reference
Effect of hepatitis B virus infection on apoptosis of a human choriocarcinoma cell line in vitro
10.1111/jog.12046 · 2013 · External reference
Hepatitis B virus X protein reduces starvation-induced cell death through activation of autophagy and inhibition of mitochondrial apoptotic pathway
10.1016/j.bbrc.2011.10.013 · 2011 · External reference
Apoptosis of hepatitis B virus-infected hepatocytes prevents release of infectious virus
10.1128/jvi.00653-10 · 2010 · External reference
