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References from Autocrine phosphatase PDP2 inhibits ferroptosis by dephosphorylating ACSL4 in the Luminal A Breast Cancer. Local targets link to admitted publications; unresolved targets remain external evidence.
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The Divergent Effects of Ovarian Steroid Hormones in the MCF-7
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Is adjuvant chemotherapy useful for women with luminal a breast cancer?
2012 · External reference
Distinguishing Low-Risk Luminal A Breast Cancer Subtypes with Ki-67 and p53 Is More Predictive of Long-Term Survival
2015 · External reference
ACSL family: The regulatory mechanisms and therapeutic implications in cancer
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Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex
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Role of the Pyruvate Dehydrogenase Complex in Metabolic Remodeling: Differential Pyruvate Dehydrogenase Complex Functions in Metabolism.
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The pyruvate dehydrogenase complex in cancer: An old metabolic gatekeeper regulated by new pathways and pharmacological agents
10.1002/ijc.29564 · 2016 · External reference
A novel null mutation in the pyruvate dehydrogenase phosphatase catalytic subunit gene (PDP1) causing pyruvate dehydrogenase complex deficiency.
10.1002/jmd2.12054 · 2019 · External reference
Prolyl Isomerase Pin1 Regulates the Stability of Hepatitis B Virus Core Protein.
10.3389/fcell.2020.00026 · 2020 · External reference
PDP-1 links the TGF-beta and IIS pathways to regulate longevity, development, and metabolism.
10.1371/journal.pgen.1001377 · 2011 · External reference
Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer
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Pyruvate dehydrogenase phosphatase catalytic subunit 2 limits Th17 differentiation
10.1073/pnas.1805717115 · 2018 · External reference
Lipid peroxidation and the subsequent cell death transmitting from ferroptotic cells to neighboring cells
10.1038/s41419-021-03613-y · 2021 · External reference
Ferroptosis: an iron-dependent form of nonapoptotic cell death
10.1016/j.cell.2012.03.042 · 2012 · External reference
Cell Death via Lipid Peroxidation and Protein Aggregation Diseases
2021 · External reference
Ferroptosis, a new form of cell death, and its relationships with tumourous diseases
10.1111/jcmm.13008 · 2017 · External reference
PKCbetaII phosphorylates ACSL4 to amplify lipid peroxidation to induce ferroptosis
10.1038/s41556-021-00818-3 · 2022 · External reference
Signaling pathways and defense mechanisms of ferroptosis
2021 · External reference
Identification of ACSL4 as a biomarker and contributor of ferroptosis
10.1016/j.bbrc.2016.08.124 · 2016 · External reference
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition
10.1038/nchembio.2239 · 2017 · External reference
Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis
10.1038/nchembio.2238 · 2017 · External reference
Energy-stress-mediated AMPK activation inhibits ferroptosis
10.1038/s41556-020-0461-8 · 2020 · External reference
Visualizing and interpreting cancer genomics data via the Xena platform
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Siglec15 shapes a non-inflamed tumor microenvironment and predicts the molecular subtype in bladder cancer
10.7150/thno.53649 · 2021 · External reference
Bioinformatics and system biology approach to identify the influences of SARS-CoV-2 infections to idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease patients
2021 · External reference
A novel ferroptosis-related gene signature can predict prognosis and influence immune microenvironment in acute myeloid leukemia
2022 · External reference
An Augmented High-Dimensional Graphical Lasso Method to Incorporate Prior Biological Knowledge for Global Network Learning.
10.3389/fgene.2021.760299 · 2021 · External reference
Development and Verification of the Hypoxia- and Immune-Associated Prognostic Signature for Pancreatic Ductal Adenocarcinoma
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Gene Ontology Consortium: going forward
10.1093/nar/gku1179 · 2015 · External reference
RNA-Seq Based Transcriptome Analysis of Endothelial Differentiation of Bone Marrow Mesenchymal Stem Cells
10.1016/j.ejvs.2019.11.003 · 2020 · External reference
Immune Response Is Key to Genetic Mechanisms of SARS-CoV-2
2022 · External reference
KOBAS-i: intelligent prioritization and exploratory visualization of biological functions for gene enrichment analysis
10.1093/nar/gkab447 · 2021 · External reference
Puerarin: A Potential Therapeutic for SARS-CoV-2 and Hantavirus Co-Infection.
10.3389/fimmu.2022.892350 · 2022 · External reference
3’-epi-12β-hydroxyfroside-mediated autophagy degradation of RIPK1/RIPK3 necrosomes leads to anergy of immunogenic cell death in triple-negative breast cancer cells
10.1016/j.phrs.2022.106613 · 2023 · External reference
Immunotherapy combining tumor and endothelium cell lysis with immune enforcement by recombinant MIP-3alpha Newcastle disease virus in a vessel-targeting liposome enhances antitumor immunity
10.1136/jitc-2021-003950 · 2022 · External reference
Selenium-GPX4 axis protects follicular helper T cells from ferroptosis
10.1038/s41590-021-00996-0 · 2021 · External reference
The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53
10.1016/j.ccr.2005.06.006 · 2005 · External reference
Targeting AURKA in Cancer: molecular mechanisms and opportunities for Cancer therapy
10.1186/s12943-020-01305-3 · 2021 · External reference
The Gene Ontology resource: enriching a GOld mine
10.1093/nar/gkaa1113 · 2021 · External reference
Gene set enrichment analysis: performance evaluation and usage guidelines
10.1093/bib/bbr049 · 2012 · External reference
MGSEA—a multivariate Gene set enrichment analysis
10.1186/s12859-019-2716-6 · 2019 · External reference
The Molecular Signatures Database (MSigDB) hallmark gene set collection.
10.1016/j.cels.2015.12.004 · 2015 · External reference
