Research graph
References from Generating PET scan patterns in Alzheimer’s by a mathematical model. Local targets link to admitted publications; unresolved targets remain external evidence.
Extracellular protein components of amyloid plaques and their roles in Alzheimer’s disease pathology
10.1186/s13024-021-00465-0 · 2021 · External reference
Glycogen synthase kinase-3 signaling in Alzheimer’s disease
10.1016/j.bbamcr.2020.118664 · 2020 · External reference
2023 Alzheimer’s Disease Facts and Figures
10.1002/alz.13016 · 2023 · External reference
Aducanumab, a novel anti-amyloid monoclonal antibody, for the treatment of Alzheimer’s disease: a comprehensive review
10.52965/001c.31925 · 2022 · External reference
PET imaging of tau pathology in Alzheimer’s disease and tauopathies
10.3389/fneur.2015.00038 · 2015 · External reference
PET amyloid-beta imaging in preclinical Alzheimer’s disease
10.1016/j.bbadis.2011.11.005 · 2012 · External reference
Diagnostic value of amyloid-PET and tau-PET: a head-to-head comparison
10.1007/s00259-021-05246-x · 2021 · External reference
Amyloid and tau positron emission tomography imaging in Alzheimer’s disease and other Tauopathies
10.3389/fnagi.2022.838034 · 2022 · External reference
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10.1002/alz.13158
10.1002/alz.13158 · External reference
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Longitudinal positron emission tomography in preventive Alzheimer’s disease drug trials, critical barriers from imaging science perspective
10.1111/bpa.12399 · 2016 · External reference
Longitudinal tau PET in ageing and Alzheimer’s disease
10.1093/brain/awy059 · 2018 · External reference
Could tau-PET imaging contribute to a better understanding of the different patterns of clinical progression in Alzheimer’s disease? A 2-year longitudinal study
10.1186/s13195-023-01237-2 · 2023 · External reference
The relationships between neuroinflammation, beta-amyloid and tau deposition in Alzheimer’s disease: a longitudinal PET study
10.1186/s12974-020-01820-6 · 2020 · External reference
Predicting MCI progression with FDG-PET and cognitive scores: a longitudinal study
10.1186/s12883-020-01728-x · 2020 · External reference
Aging, cellular senescence, and Alzheimer’s disease
10.3390/ijms23041989 · 2022 · External reference
Increased post-mitotic senescence in aged human neurons is a pathological feature of Alzheimer’s disease
10.1016/j.stem.2022.11.010 · 2022 · External reference
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Role of reactive oxygen species in the progression of Alzheimer’s disease
10.1016/j.drudis.2020.12.004 · 2021 · External reference
The impact of systemic inflammation on Alzheimer’s disease pathology
10.3389/fimmu.2021.796867 · 2022 · External reference
Inflammation as a central mechanism in Alzheimer’s disease
10.1016/j.trci.2018.06.014 · 2018 · External reference
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Mathematical model on Alzheimer’s disease
10.1186/s12918-016-0348-2 · 2016 · External reference
Protein-protein interactions in neurodegenerative diseases: A conspiracy theory
10.1371/journal.pcbi.1008267 · 2020 · External reference
Alzheimer’s disease: a mathematical model for onset and progression
2017 · External reference
The amyloid cascade hypothesis and Alzheimer’s disease: A mathematical model
10.1017/s0956792520000339 · 2021 · External reference
A sensitivity analysis of a mathematical model for the synergistic interplay of amyloid beta and tau on the dynamics of Alzheimer’s disease
10.1016/j.brain.2020.100020 · 2021 · External reference
The development of a stochastic mathematical model of Alzheimer’s disease to help improve the design of clinical trials of potential treatments
10.1371/journal.pone.0190615 · 2018 · External reference
Alzheimer’s disease: analysis of a mathematical model incorporating the role of prions
10.1007/s00285-013-0732-0 · 2014 · External reference
Fitting the epidemiology and neuropathology of the early stages of Alzheimer’s disease to prevent dementia
10.1186/s13195-014-0079-9 · 2015 · External reference
Mathematical modeling for the pathogenesis of Alzheimer’s disease
10.1371/journal.pone.0015176 · 2010 · External reference
A Mathematical model of the impact of novel treatments on the Aβ-burden in the Alzheimer’s Brain, CSF and Plasma
10.1006/bulm.2002.0304 · 2002 · External reference
Mathematical model and artificial intelligence for diagnosis of Alzheimer’s disease
10.1140/epjp/s13360-023-04128-5 · 2023 · External reference
Aβ peptides in human plasma and tissues and their significance for Alzheimer’s disease
10.1016/j.jalz.2008.10.004 · 2009 · External reference
Highly increased CSF tau protein and decreased β-amyloid (1-42) in sporadic CJD: a discrimination from Alzheimer’s disease?
10.1136/jnnp.71.3.401 · 2001 · External reference
Hyperactivation of monocytes and macrophages in MCI patients contributes to the progression of Alzheimer’s disease
10.1186/s12979-021-00236-x · 2021 · External reference
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Cell number changes in Alzheimer’s disease relate to dementia, not to plaques and tangles
10.1093/brain/awt273 · 2013 · External reference
The amyloid-β pathway in Alzheimer’s disease
10.1038/s41380-021-01249-0 · 2021 · External reference
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Lithium, phenserine, memantine and pioglitazone reverse memory deficit and restore phospho-GSK3β decreased in hippocampus in intracerebroventricular streptozotocin induced memory deficit model
10.1016/j.brainres.2011.09.056 · 2011 · External reference
Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration
10.1111/j.1460-9568.2006.05226.x · 2007 · External reference
The neuropathological diagnosis of Alzheimer’s disease
10.1186/s13024-019-0333-5 · 2019 · External reference
Amyloid β-42 induces neuronal apoptosis by targeting mitochondria
10.3892/mmr.2017.7203 · 2017 · External reference
Validation of plasma amyloid-β 42/40 for detecting Alzheimer disease amyloid plaques
2022 · External reference
Microglia function in Alzheimer’s disease
10.3389/fphar.2012.00014 · 2012 · External reference
Role of microglial cells in Alzheimer’s disease tau propagation
10.3389/fnagi.2019.00271 · 2019 · External reference
The many faces of astrocytes in Alzheimer’s disease
10.3389/fneur.2021.619626 · 2021 · External reference
YAP-dependent necrosis occurs in early stages of Alzheimer’s disease and regulates mouse model pathology
10.1038/s41467-020-14353-6 · 2020 · External reference
Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells
10.1128/iai.73.4.1907-1916.2005 · 2005 · External reference
Disruption of oligodendrocyte progenitor cells is an early sign of pathology in the triple transgenic mouse model of Alzheimer’s disease
10.1016/j.neurobiolaging.2020.05.016 · 2020 · External reference
Deriving the bidomain model of cardiac electrophysiology from a cell-based model; properties and comparisons
10.3389/fphys.2021.811029 · 2022 · External reference
Mitochondrial fission promotes the continued clearance of apoptotic cells by macrophages
10.1016/j.cell.2017.08.041 · 2017 · External reference
Clearance of amyloid-β peptides by microglia and macrophages: the issue of what, when and where
10.2217/fnl.12.6 · 2012 · External reference
How to get from here to there: macrophage recruitment in Alzheimer’s disease
10.2174/156720511795256017 · 2011 · External reference
Microglia in Alzheimer’s disease
10.1083/jcb.201709069 · 2018 · External reference
Tau in Alzheimer disease and related tauopathies
10.2174/156720510793611592 · 2010 · External reference
GSK3 and tau: two convergence points in Alzheimer’s disease
10.3233/jad-2012-129025 · 2013 · External reference
Interaction between Aβ and tau in the pathogenesis of Alzheimer’s disease
10.7150/ijbs.57078 · 2021 · External reference
Microglia dynamics and function in the CNS
10.1016/j.conb.2010.07.002 · 2010 · External reference
Microglial motility in Alzheimer’s disease and after Aβ42 immunotherapy: a human post-mortem study
10.1186/s40478-019-0828-x · 2019 · External reference
What do microglia really do in healthy adult brain?
10.3390/cells8101293 · 2019 · External reference
Friend, foe or both? Immune activity in Alzheimer’s disease
10.3389/fnagi.2019.00337 · 2019 · External reference
Reactive astrogliosis: A friend or foe in the pathogenesis of Alzheimer’s disease
10.1111/jnc.15565 · 2023 · External reference
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Neuroinflammation in the pathogenesis of Alzheimer’s disease. A rational framework for the search of novel therapeutic approaches
10.3389/fncel.2014.00112 · 2014 · External reference
Tumor necrosis factor α inhibition for Alzheimer’s disease
10.1177/1179573517709278 · 2017 · External reference
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Similar microglial cell densities across brain structures and mammalian species: implications for brain tissue function
10.1523/jneurosci.2339-19.2020 · 2020 · External reference
The search for true numbers of neurons and glial cells in the human brain: A review of 150 years of cell counting
10.1002/cne.24040 · 2016 · External reference
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The role of microglia in Alzheimer’s disease and progress of treatment
10.1002/ibra.12023 · 2022 · External reference
Characterization of 3 novel tau radiopharmaceuticals, 11C-RO-963, 11C-RO-643, and 18F-RO-948, in healthy controls and in Alzheimer subjects
10.2967/jnumed.118.209916 · 2018 · External reference
Aducanumab and its effects on tau pathology: is this the turning point of amyloid hypothesis?
10.3390/ijms23042011 · 2022 · External reference
