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References from Prognostic value of PRR11 and immune cell infiltration in Ewing sarcoma. Local targets link to admitted publications; unresolved targets remain external evidence.
Identification of a Novel FUS/ETV4 Fusion and Comparative Analysis with Other Ewing Sarcoma Fusion Proteins
10.1158/1541-7786.mcr-21-0354 · 2021 · External reference
Ewing sarcoma.
10.1038/s41572-018-0003-x · 2018 · External reference
Ewing sarcoma.
2021 · External reference
Risk of recurrence and survival after relapse in patients with Ewing sarcoma
10.1002/pbc.23040 · 2011 · External reference
Ewing Sarcoma: Current Management and Future Approaches Through Collaboration.
10.1200/jco.2014.59.5256 · 2015 · External reference
NCBI GEO: archive for functional genomics data sets—update
2013 · External reference
TrkC, a novel prognostic marker, induces and maintains cell survival and metastatic dissemination of Ewing sarcoma by inhibiting EWSR1-FLI1 degradation.
10.1038/s41419-022-05275-w · 2022 · External reference
Adverse prognostic impact of the loss of STAG2 protein expression in patients with newly diagnosed localised Ewing sarcoma: A report from the Children’s Oncology Group
2022 · External reference
Translational evidence for RRM2 as a prognostic biomarker and therapeutic target in Ewing sarcoma
10.1186/s12943-021-01393-9 · 2021 · External reference
Prognostic significance of miR-34a in Ewing sarcoma is associated with cyclin D1 and ki-67 expression.
10.1093/annonc/mdu249 · 2014 · External reference
The prognostic value of autophagy related genes with potential protective function in Ewing sarcoma
10.1186/s12859-022-04849-x · 2022 · External reference
Chimeric antigen receptor T cells for sustained remissions in leukemia
10.1056/nejmoa1407222 · 2014 · External reference
Role of immunotherapy in Ewing sarcoma
10.1136/jitc-2020-000653 · 2020 · External reference
Current State of Immunotherapy and Mechanisms of Immune Evasion in Ewing Sarcoma and Osteosarcoma.
10.3390/cancers15010272 · 2022 · External reference
Targeting the tumor microenvironment of Ewing sarcoma.
10.2217/imt-2020-0341 · 2021 · External reference
limma powers differential expression analyses for RNA-sequencing and microarray studies
10.1093/nar/gkv007 · 2015 · External reference
Regularization Paths for Generalized Linear Models via Coordinate Descent.
10.18637/jss.v033.i01 · 2010 · External reference
The lasso method for variable selection in the Cox model.
10.1002/(sici)1097-0258(19970228)16:4<385::aid-sim380>3.0.co;2-3 · 1997 · External reference
The STRING database in 2021: customizable protein-protein networks, and functional characterization of user-uploaded gene/measurement sets
10.1093/nar/gkaa1074 · 2021 · External reference
xCell: digitally portraying the tissue cellular heterogeneity landscape
10.1186/s13059-017-1349-1 · 2017 · External reference
Prediction and analysis of essential genes using the enrichments of gene ontology and KEGG pathways
10.1371/journal.pone.0184129 · 2017 · External reference
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
10.1073/pnas.0506580102 · 2005 · External reference
Cytoscape StringApp: Network Analysis and Visualization of Proteomics Data
10.1021/acs.jproteome.8b00702 · 2019 · External reference
cytoHubba: identifying hub objects and sub-networks from complex interactome
10.1186/1752-0509-8-s4-s11 · 2014 · External reference
DAX1, a direct target of EWS/FLI1 oncoprotein, is a principal regulator of cell-cycle progression in Ewing’s tumor cells
10.1038/onc.2008.203 · 2008 · External reference
Inhibition of the oncogenic fusion protein EWS-FLI1 causes G(2)-M cell cycle arrest and enhanced vincristine sensitivity in Ewing’s sarcoma.
10.1126/scisignal.aam8429 · 2017 · External reference
TTK kinase is essential for the centrosomal localization of TACC2
10.1016/j.febslet.2004.06.092 · 2004 · External reference
Leader of the SAC: molecular mechanisms of Mps1/TTK regulation in mitosis.
10.1098/rsob.180109 · 2018 · External reference
Expression of TTK, a novel human protein kinase, is associated with cell proliferation
10.1016/s0021-9258(19)49633-6 · 1992 · External reference
ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules
10.15252/embr.201541823 · 2016 · External reference
Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex
10.1038/ncb3511 · 2017 · External reference
The differential distributions of ASPM isoforms and their roles in Wnt signaling, cell cycle progression, and pancreatic cancer prognosis
10.1002/path.5341 · 2019 · External reference
Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis
10.1038/ncb953 · 2003 · External reference
CENP-F is a protein of the nuclear matrix that assembles onto kinetochores at late G2 and is rapidly degraded after mitosis
10.1083/jcb.130.3.507 · 1995 · External reference
PRR11 regulates late-S to G2/M phase progression and induces premature chromatin condensation (PCC).
10.1016/j.bbrc.2015.01.139 · 2015 · External reference
PRR11 promotes cell proliferation by regulating PTTG1 through interacting with E2F1 transcription factor in pan-cancer.
10.3389/fmolb.2022.877320 · 2022 · External reference
Proline-rich 11 (PRR11) drives F-actin assembly by recruiting the actin-related protein 2/3 complex in human non-small cell lung carcinoma.
10.1074/jbc.ra119.012260 · 2020 · External reference
PRR11 is a novel gene implicated in cell cycle progression and lung cancer
10.1016/j.biocel.2012.12.002 · 2013 · External reference
PRR11 promotes ccRCC tumorigenesis by regulating E2F1 stability.
10.1172/jci.insight.145172 · 2021 · External reference
The oncogenic potential of PRR11 gene in Tongue Squamous Cell Carcinoma cells
10.7150/jca.29265 · 2019 · External reference
PRR11 unveiled as a top candidate biomarker within the RBM3-regulated transcriptome in pancreatic cancer
10.1002/cjp2.238 · 2022 · External reference
PRR11 Is a Prognostic Marker and Potential Oncogene in Patients with Gastric Cancer.
10.1371/journal.pone.0128943 · 2015 · External reference
Down-regulation of PRR11 affects the proliferation, migration and invasion of osteosarcoma by inhibiting the Wnt/β-catenin pathway
10.7150/jca.62491 · 2021 · External reference
Proline rich 11 (PRR11) overexpression amplifies PI3K signaling and promotes antiestrogen resistance in breast cancer.
10.1038/s41467-020-19291-x · 2020 · External reference
The prognostic influence of tumour-infiltrating lymphocytes in cancer: a systematic review with meta-analysis
10.1038/bjc.2011.189 · 2011 · External reference
Reduced human leukocyte antigen expression in advanced-stage Ewing sarcoma: implications for immune recognition
10.1002/path.2537 · 2009 · External reference
Identification of poorly differentiated synovial sarcoma: a comparison of clinicopathological and cytogenetic features with those of typical synovial sarcoma.
10.1046/j.1365-2559.2003.01668.x · 2003 · External reference
An immune-related gene signature for determining Ewing sarcoma prognosis based on machine learning
10.1007/s00432-020-03396-3 · 2021 · External reference
Cancer-related inflammation.
10.1038/nature07205 · 2008 · External reference
Impact of immune cells on the hallmarks of cancer: A literature review
10.1016/j.critrevonc.2021.103541 · 2021 · External reference
Mast Cell: A Multi-Functional Master Cell.
2015 · External reference
Prognostic value of GLCE and infiltrating immune cells in Ewing sarcoma.
10.1016/j.heliyon.2023.e19357 · 2023 · External reference
Dendritic and mast cell involvement in the inflammatory response to primary malignant bone tumours
10.1186/s13569-016-0053-3 · 2016 · External reference
ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours
10.1038/nature09409 · 2010 · External reference
C-kit expression in pediatric solid tumors: a comparative immunohistochemical study.
10.1097/00000478-200204000-00011 · 2002 · External reference
Imatinib inhibits proliferation of Ewing tumor cells mediated by the stem cell factor/KIT receptor pathway, and sensitizes cells to vincristine and doxorubicin-induced apoptosis
10.1158/1078-0432.ccr-0778-03 · 2004 · External reference
C-kit receptor expression in Ewing’s sarcoma: lack of prognostic value but therapeutic targeting opportunities in appropriate conditions
10.1200/jco.2003.11.111 · 2003 · External reference