Research graph
References from Integrating and optimizing tonabersat in standard glioblastoma therapy: A preclinical study. Local targets link to admitted publications; unresolved targets remain external evidence.
A Review of Newly Diagnosed Glioblastoma
10.3389/fonc.2020.574012 · 2021 · External reference
Glioma
2015 · External reference
Neuroscience: Glia—More than Just Brain Glue
10.1038/457675a · 2009 · External reference
Connexins, Gap Junctions, and Glia
10.1002/wmts.87 · 2013 · External reference
Glial Cells and Integrity of the Nervous System
10.1007/978-3-319-40764-7_1 · 2016 · External reference
The 2021 WHO Classification of Tumors of the Central Nervous System: A Summary
10.1093/neuonc/noab106 · 2021 · External reference
Advanced Magnetic Resonance Imaging of the Physical Processes in Human Glioblastoma
10.1158/0008-5472.can-14-0383 · 2014 · External reference
The Definition of Primary and Secondary Glioblastoma
10.1158/1078-0432.ccr-12-3002 · 2013 · External reference
Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma
10.1056/nejmoa043330 · 2005 · External reference
Survival in Glioblastoma: A Review on the Impact of Treatment Modalities
10.1007/s12094-016-1497-x · 2016 · External reference
Brain Tumour Cells Interconnect to a Functional and Resistant Network
10.1038/nature16071 · 2015 · External reference
Unresolved reference
External reference
Cancer Connectors: Connexins, Gap Junctions, and Communication
10.3389/fonc.2018.00646 · 2018 · External reference
Emerging Intersections between Neuroscience and Glioma Biology
10.1038/s41593-019-0540-y · 2019 · External reference
Connexins in Cancer: Bridging the Gap to the Clinic
10.1038/s41388-019-0741-6 · 2019 · External reference
Gap Junctions Modulate Glioma Invasion by Direct Transfer of MicroRNA
10.18632/oncotarget.3904 · 2015 · External reference
Contribution of Gap Junctional Communication between Tumor Cells and Astroglia to the Invasion of the Brain Parenchyma by Human Glioblastomas
10.1186/1471-2121-6-7 · 2005 · External reference
Glioblastoma-Astrocyte Connexin 43 Gap Junctions Promote Tumor Invasion
10.1158/1541-7786.mcr-21-0199 · 2022 · External reference
Astrocytes Promote Glioma Invasion via the Gap Junction Protein Connexin43
10.1038/onc.2015.210 · 2016 · External reference
A Malignant Cellular Network in Gliomas: Potential Clinical Implications
10.1093/neuonc/now014 · 2016 · External reference
Targeting Different Domains of Gap Junction Protein to Control Malignant Glioma
10.1093/neuonc/nox207 · 2018 · External reference
Reactive Astrocytes Protect Melanoma Cells from Chemotherapy by Sequestering Intracellular Calcium through Gap Junction Communication Channels
10.1593/neo.10602 · 2010 · External reference
Gap Junctions and Cancer: Communicating for 50 Years
10.1038/nrc.2016.105 · 2016 · External reference
Tonabersat Inhibits Trigeminal Ganglion Neuronal-Satellite Glial Cell Signaling
10.1111/j.1526-4610.2008.01262.x · 2009 · External reference
Connexin Hemichannel Block Using Orally Delivered Tonabersat Improves Outcomes in Animal Models of Retinal Disease
10.1007/s13311-019-00786-5 · 2020 · External reference
Carcinoma-Astrocyte Gap Junctions Promote Brain Metastasis by CGAMP Transfer
10.1038/nature18268 · 2016 · External reference
Tonabersat Prevents Inflammatory Damage in the Central Nervous System by Blocking Connexin43 Hemichannels
10.1007/s13311-017-0536-9 · 2017 · External reference
Pathophysiology of Migraine
10.1016/j.ncl.2008.11.012 · 2009 · External reference
Influence of Drugs on Gap Junctions in Glioma Cell Lines and Primary Astrocytes in Vitro
2014 · External reference
Progress Report on New Antiepileptic Drugs: A Summary of the Eleventh Eilat Conference (EILAT XI)
10.1016/j.eplepsyres.2012.10.001 · 2013 · External reference
Unresolved reference
2017 · External reference
Adjuvant Therapeutic Potential of Tonabersat in the Standard Treatment of Glioblastoma: A Preclinical F98 Glioblastoma Rat Model Study
10.1371/journal.pone.0224130 · 2019 · External reference
Rat Brain Tumor Models in Experimental Neuro-Oncology: The C6, 9L, T9, RG2, F98, BT4C, RT-2 and CNS-1 Gliomas
10.1007/s11060-009-9875-7 · 2009 · External reference
Rat and Mouse Brain Tumor Models for Experimental Neuro-Oncology Research
10.1093/jnen/nlac021 · 2022 · External reference
The Importance of a Syngeneic Glioma Implantation Model: Comparison of the F98 Cell Line in Fischer and Long-Evans Rats
2005 · External reference
Current Brain Tumour Models with Particular Consideration of the Transplantation Techniques
1986 · External reference
Molecular Mechanisms of Treatment Resistance in Glioblastoma
2021 · External reference
Combined-Therapeutic Strategies Synergistically Potentiate Glioblastoma Multiforme Treatment via Nanotechnology
10.7150/thno.40298 · 2020 · External reference
An Improved F98 Glioblastoma Rat Model to Evaluate Novel Treatment Strategies Incorporating the Standard of Care
10.1371/journal.pone.0296360 · 2024 · External reference
Morphological Characterization of Nitrosourea-Induced Glioma Cell Lines and Clones
10.1007/bf00688846 · 1980 · External reference
Sample Size Calculation in Animal Studies Using Resource Equation Approach
10.21315/mjms2017.24.5.11 · 2017 · External reference
How to Calculate Sample Size in Animal Studies?
2013 · External reference
MR-Pathological Comparison in F98-Fischer Glioma Model Using a Human Gantry
10.1017/s0317167100004753 · 2006 · External reference
The Laboratory Rat: Relating Its Age With Human’s
2013 · External reference
Tonabersat, a Novel Gap-Junction Modulator for the Prevention of Migraine
10.1111/j.1468-2982.2009.01973.x · 2009 · External reference
The Evolution of Tumour Composition During Fractionated Radiotherapy: Implications for Outcome
10.1007/s11538-018-0391-9 · 2018 · External reference
Opposing Roles of Connexin43 in Glioma Progression
10.1016/j.bbamem.2011.10.022 · 2012 · External reference
Conflicting Roles of Connexin43 in Tumor Invasion and Growth in the Central Nervous System
2018 · External reference
Connexins in Cancer: Bridging the Gap to the Clinic
10.1038/s41388-019-0741-6 · 2019 · External reference
Radiosensitization of Glioma Cells by Temozolomide (TMZ): A Colony Formation Assay
10.31661/jbpe.v0i0.1223 · 2022 · External reference
In Vitro Radiosensitizing Effects of Temozolomide on U87MG Cell Lines of Human Glioblastoma Multiforme
2017 · External reference
Blood-Brain Barrier Permeability in Healthy Rats and Rats with Experimental C6 Glioma after Fractionated Radiotherapy of the Brain
10.17116/neiro201579315-26 · 2015 · External reference
Treatment of Poorly Differentiated Glioma Using a Combination of Monoclonal Antibodies to Extracellular Connexin-43 Fragment, Temozolomide, and Radiotherapy
10.1007/s10517-014-2603-0 · 2014 · External reference
Antitumor Effects of Monoclonal Antibodies to Connexin 43 Extracellular Fragment in Induced Low-Differentiated Glioma
10.1007/s10517-012-1667-y · 2012 · External reference
Orally Delivered Connexin43 Hemichannel Blocker, Tonabersat, Inhibits Vascular Breakdown and Inflammasome Activation in a Mouse Model of Diabetic Retinopathy
10.3390/ijms24043876 · 2023 · External reference
Gap Junctions and Neurological Disorders of the Central Nervous System
10.1016/j.bbamem.2004.01.009 · 2004 · External reference
Early Compared with Late Radiotherapy in Combined Modality Treatment for Limited Disease Small-Cell Lung Cancer: A London Lung Cancer Group Multicenter Randomized Clinical Trial and Meta-Analysis
10.1200/jco.2005.05.3181 · 2006 · External reference
Epilepsy in Glioblastoma Patients: Basic Mechanisms and Current Problems in Treatment
10.1586/ecp.13.12 · 2013 · External reference
Development of a Rat Model for Glioma-Related Epilepsy
10.3390/ijms21196999 · 2020 · External reference
Epilepsy in Glioma Patients: Mechanisms, Management, and Impact of Anticonvulsant Therapy
10.1093/neuonc/nov269 · 2016 · External reference
Seizure Characteristics and Prognostic Factors of Gliomas
10.1111/epi.12437 · 2013 · External reference
