Research graph
References from Lethal metabolism of Candida albicans respiratory mutants. Local targets link to admitted publications; unresolved targets remain external evidence.
Threats Posed by the Fungal Kingdom to Humans, Wildlife, and Agriculture
10.1128/mbio.00449-20 · 2020 · External reference
Worldwide emergence of resistance to antifungal drugs challenges human health and food security
10.1126/science.aap7999 · 2018 · External reference
Pan-cancer analyses reveal cancer-type-specific fungal ecologies and bacteriome interactions
10.1016/j.cell.2022.09.005 · 2022 · External reference
A pan-cancer mycobiome analysis reveals fungal involvement in gastrointestinal and lung tumors
10.1016/j.cell.2022.09.015 · 2022 · External reference
Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer
10.1016/j.ccell.2022.01.003 · 2022 · External reference
Hidden killers: human fungal infections.
10.1126/scitranslmed.3004404 · 2012 · External reference
Economic Burden of Fungal Diseases in the United States.
10.1093/ofid/ofac097 · 2022 · External reference
The antifungal pipeline: a reality check.
10.1038/nrd.2017.46 · 2017 · External reference
Identification of Small-Molecule Inhibitors of the Salmonella FraB Deglycase Using a Live-Cell Assay.
10.1128/spectrum.04606-22 · 2023 · External reference
Endogenous toxic metabolites and implications in cancer therapy
10.1038/s41388-020-01395-9 · 2020 · External reference
Fructose-asparagine is a primary nutrient during growth of Salmonella in the inflamed intestine.
10.1371/journal.ppat.1004209 · 2014 · External reference
Measurement of Fructose-Asparagine Concentrations in Human and Animal Foods
10.1021/acs.jafc.7b04237 · 2018 · External reference
A metabolic intermediate of the fructose-asparagine utilization pathway inhibits growth of a Salmonella fraB mutant.
10.1038/srep28117 · 2016 · External reference
Sugar-Phosphate Toxicities Attenuate Salmonella Fitness in the Gut
10.1128/jb.00344-22 · 2022 · External reference
Sugar-Phosphate Toxicities.
10.1128/mmbr.00123-21 · 2021 · External reference
Homoserine toxicity in Saccharomyces cerevisiae and Candida albicans homoserine kinase (thr1Delta) mutants.
10.1128/ec.00044-10 · 2010 · External reference
The multicatalytic compartment of propionyl-CoA synthase sequesters a toxic metabolite
10.1038/s41589-018-0153-x · 2018 · External reference
The Ruegeria pomeroyi acuI gene has a role in DMSP catabolism and resembles yhdH of E. coli and other bacteria in conferring resistance to acrylate
10.1371/journal.pone.0035947 · 2012 · External reference
Secondary mitochondrial dysfunction in propionic aciduria: a pathogenic role for endogenous mitochondrial toxins
10.1042/bj20060221 · 2006 · External reference
Pathophysiology of propionic and methylmalonic acidemias. Part 1: Complications
10.1002/jimd.12129 · 2019 · External reference
Microbial pathway for anaerobic 5’-methylthioadenosine metabolism coupled to ethylene formation
10.1073/pnas.1711625114 · 2017 · External reference
Metabolite profiling reveals YihU as a novel hydroxybutyrate dehydrogenase for alternative succinic semialdehyde metabolism in Escherichia coli
10.1074/jbc.m109.002089 · 2009 · External reference
Regulation of Glutarate Catabolism by GntR Family Regulator CsiR and LysR Family Regulator GcdR in Pseudomonas putida KT2440.
10.1128/mbio.01570-19 · 2019 · External reference
Essential genes in Bacillus subtilis: a re-evaluation after ten years.
10.1039/c3mb25595f · 2013 · External reference
’Nothing of chemistry disappears in biology’: the Top 30 damage-prone endogenous metabolites.
10.1042/bst20160073 · 2016 · External reference
Challenges in Identifying the Dark Molecules of Life.
10.1146/annurev-anchem-061318-114959 · 2019 · External reference
Enzyme promiscuity: a mechanistic and evolutionary perspective
10.1146/annurev-biochem-030409-143718 · 2010 · External reference
Metabolite damage and its repair or pre-emption
10.1038/nchembio.1141 · 2013 · External reference
Metabolite Repair Enzymes Control Metabolic Damage in Glycolysis
10.1016/j.tibs.2019.07.004 · 2020 · External reference
Azole susceptibility and transcriptome profiling in Candida albicans mitochondrial electron transport chain complex I mutants
10.1128/aac.01520-12 · 2013 · External reference
Evaluation of vaginal antifungal formulations in vivo
10.1136/pgmj.55.647.648 · 1979 · External reference
Unique, Diverged, and Conserved Mitochondrial Functions Influencing Candida albicans Respiration.
2019 · External reference
Unresolved reference
2006 · External reference
Unresolved reference
2022 · External reference
Separation of nucleotides, nucleosides and bases on a new gel filtration material
10.1016/s0021-9673(01)97380-7 · 1965 · External reference
Use of polyacrylamide gel columns for the separation of nucleotides
10.1016/0014-5793(69)80327-3 · 1969 · External reference
Separation of nucleosides on polyacrylamide gel columns
10.1016/0005-2787(68)90328-6 · 1968 · External reference
Fungal nucleobase transporters
10.1111/j.1574-6976.2007.00083.x · 2007 · External reference
Purine Acquisition and Synthesis by Human Fungal Pathogens.
10.3390/microorganisms5020033 · 2017 · External reference
Ethanol tolerance and the induction of stress proteins by ethanol in Candida albicans
1988 · External reference
Recent progress in the consideration of flavor ingredients under the Food Additives Amendment. 3
1965 · External reference
GRAS Flavoring Substances 29
2020 · External reference
Dynamics of a fixed-bed adsorptive reactor for synthesis of diethylacetal
10.1002/aic.690480319 · 2002 · External reference
Acetaldehyde as Key Compound for the Authenticity of Sherry Wines: A Study Covering 5 Decades.
10.1111/1541-4337.12159 · 2015 · External reference
Volatile metabolites produced by different flor yeast strains during wine biological ageing
10.1016/j.foodres.2019.108771 · 2020 · External reference
Simultaneous determination of diethylacetal and acetaldehyde during beer fermentation and storage process
10.1002/jsfa.9008 · 2018 · External reference
Formation of acetals in rum
1975 · External reference
Novel process for diethylacetal synthesis
10.1002/aic.10531 · 2005 · External reference
A Simple and Versatile Method for the Formation of Acetals/Ketals Using Trace Conventional Acids.
10.1021/acsomega.8b00159 · 2018 · External reference
New procedures for the preparation of complexes of ribosomes with polyuridylic acid
10.1021/bi00861a006 · 1967 · External reference
The action of pancreatic desoxyribonuclease. I. Isolation of mono- and dinucleotides
10.1016/s0021-9258(18)65663-7 · 1954 · External reference
Studies of the specificity of deoxyribonuclease I. III. Hydrolysis of chains carrying a monoesterified phosphate on carbon 5’
1961 · External reference
Excavating an active site: the nucleobase specificity of ribonuclease A
10.1021/bi001862f · 2000 · External reference
Evaluation of Brewer’s spent yeast to produce flavor enhancer nucleotides: influence of serial repitching
10.1021/jf4021619 · 2013 · External reference
Degradation of RNA during the autolysis of Saccharomyces cerevisiae produces predominantly ribonucleotides
10.1007/s10295-005-0008-9 · 2005 · External reference
Virulence of a phosphoribosylaminoimidazole carboxylase-deficient Candida albicans strain in an immunosuppressed murine model of systemic candidiasis
10.1128/iai.69.4.2542-2548.2001 · 2001 · External reference
Characterization of extracellular nucleotide metabolism in Candida albicans
10.1093/femsle/fnv212 · 2016 · External reference
Uptake of pyrimidines and their derivatives into Candida glabrata and Candida albicans
10.1099/00221287-136-8-1475 · 1990 · External reference
Molecular mechanisms of primary resistance to flucytosine in Candida albicans
10.1128/aac.48.11.4377-4386.2004 · 2004 · External reference
Functional characterization of a H+/nucleoside co-transporter (CaCNT) from Candida albicans, a fungal member of the concentrative nucleoside transporter (CNT) family of membrane proteins.
10.1002/yea.1000 · 2003 · External reference
Allelic isoforms of the H+/nucleoside co-transporter (CaCNT) from Candida albicans reveal separate high- and low-affinity transport systems for nucleosides.
10.1002/yea.1178 · 2004 · External reference
The evolution of nucleoside analogue antivirals: A review for chemists and non-chemists. Part 1: Early structural modifications to the nucleoside scaffold.
10.1016/j.antiviral.2018.04.004 · 2018 · External reference
Nucleobase-modified nucleosides and nucleotides: Applications in biochemistry, synthetic biology, and drug discovery
10.3389/fchem.2022.1051525 · 2022 · External reference
Mechanism of adenine toxicity in Escherichia coli
10.1128/jb.149.3.923-930.1982 · 1982 · External reference
Mechanism of adenine inhibition in adenine-sensitive mutants of Salmonella typhimurium
10.1128/jb.91.2.507-513.1966 · 1966 · External reference
Inhibition of the Biosynthesis of the Pyrimidine Portion of Thiamine by Adenosine
10.1128/jb.88.4.1024-1029.1964 · 1964 · External reference
Cytotoxic and metabolic effects of adenosine and adenine on human lymphoblasts
1978 · External reference
Ultraviolet microscopy of purines and amino acids in the vacuole of Candida albicans
10.1128/jb.96.1.259-265.1968 · 1968 · External reference
Grf10 and Bas1 Regulate Transcription of Adenylate and One-Carbon Biosynthesis Genes and Affect Virulence in the Human Fungal Pathogen Candida albicans.
10.1128/msphere.00161-17 · 2017 · External reference
Grf10 regulates the response to copper, iron, and phosphate in Candida albicans.
10.1093/g3journal/jkad070 · 2023 · External reference
Dual control of NAD(+) synthesis by purine metabolites in yeast.
2019 · External reference
Metabolomics and proteomics identify the toxic form and the associated cellular binding targets of the anti-proliferative drug AICAR
10.1074/jbc.ra118.004964 · 2019 · External reference
