Research graph
References from Tamarix aphylla derived metabolites ameliorate indomethacin-induced gastric ulcers in rats by modulating the MAPK signaling pathway, alleviating oxidative stress and inflammation: In vivo study supported by pharmacological network analysis. Local targets link to admitted publications; unresolved targets remain external evidence.
The global incidence of peptic ulcer disease and its complications at the turn of the 21st century: A systematic review: 1199
10.14309/00000434-201810001-01199 · 2018 · External reference
Antiulcer potential of Olea europea L. cv. arbequina leaf extract supported by metabolic profiling and molecular docking
10.3390/antiox10050644 · 2021 · External reference
Mechanistic insights into the protective effects of chlorogenic acid against indomethacin-induced gastric ulcer in rats: Modulation of the cross talk between autophagy and apoptosis signaling
10.1016/j.lfs.2021.119370 · 2021 · External reference
Gastro-protective, therapeutic and anti-inflammatory activities of Pistacia lentiscus L. fatty oil against ethanol-induced gastric ulcers in rats
10.1016/j.jep.2018.05.040 · 2018 · External reference
Ameliorating and protective effects mesalazine on ethanol-induced gastric ulcers in experimental rats
10.1016/j.ejphar.2020.173573 · 2020 · External reference
Gastroprotective effect of andrographolide sodium bisulfite against indomethacin-induced gastric ulceration in rats
10.1016/j.intimp.2015.04.025 · 2015 · External reference
AMPK/mTOR-driven autophagy & Nrf2/HO-1 cascade modulation by amentoflavone ameliorates indomethacin-induced gastric ulcer
10.1016/j.biopha.2022.113200 · 2022 · External reference
Gastric acid inhibitor aggravates indomethacin-induced small intestinal injury via reducing Lactobacillus johnsonii
10.1038/s41598-019-53559-7 · 2019 · External reference
Maintenance therapy with proton pump inhibitors and risk of gastric cancer: a nationwide population-based cohort study in Sweden
10.1136/bmjopen-2017-017739 · 2017 · External reference
Medicinal plants in the treatment of peptic ulcer disease: A review
10.2174/1389557520666191227151939 · 2020 · External reference
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2023 · External reference
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2023 · External reference
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2019 · External reference
Assessing the Antiproliferative Potential of a Novel Combretastatin A4 Derivative via Modulating Apoptosis, MAPK/ERK and PI3K/AKT Pathways in Human Breast Cancer Cells
10.31083/j.fbl2808185 · 2023 · External reference
A novel role of irbesartan in gastroprotection against indomethacin-induced gastric injury in rats: targeting DDAH/ADMA and EGFR/ERK signaling
10.1038/s41598-018-22727-6 · 2018 · External reference
Evaluating the mucoprotective effect of polydeoxyribonucleotide against indomethacin-induced gastropathy via the MAPK/NF-κB signaling pathway in rats
10.1016/j.ejphar.2020.172952 · 2020 · External reference
A bis-resorcinol resveratrol congener prevents indomethacin-induced gastric ulceration by inhibiting TNF-α as well as NF-κB and JNK pathways
10.1080/10715762.2019.1572887 · 2019 · External reference
Processed Aloe vera gel attenuates non-steroidal anti-inflammatory drug (NSAID)-induced small intestinal injury by enhancing mucin expression
10.1039/c9fo01307e · 2019 · External reference
Alhazmi HAJM. Modern approaches in the discovery and development of plant-based natural products and their analogues as potential therapeutic agents
10.3390/molecules27020349 · 2022 · External reference
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2022 · External reference
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2020 · External reference
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2022 · External reference
Abelmoschus eculentus Seed Extract Exhibits In Vitro and In Vivo Anti-Alzheimer’s Potential Supported by Metabolomic and Computational Investigation
10.3390/plants12122382 · 2023 · External reference
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2022 · External reference
Antiulcer potential and molecular docking of flavonoids from Ocimum forskolei Benth
2021 · External reference
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2022 · External reference
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2022 · External reference
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2022 · External reference
Metabolic profiling, histopathological anti-ulcer study, molecular docking and molecular dynamics of ursolic acid isolated from Ocimum forskolei Benth
2020 · External reference
The cosmetic potential of the medicinal halophyte Tamarix gallica L
2021 · External reference
Evolution
2019 · External reference
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2020 · External reference
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2023 · External reference
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2021 · External reference
Technology
2019 · External reference
10.1177/1940082919869480
10.1177/1940082919869480 · External reference
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2020 · External reference
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2020 · External reference
Tamarix aphylla (L.) Karst
2019 · External reference
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2022 · External reference
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2020 · External reference
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2018 · External reference
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2020 · External reference
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2019 · External reference
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2022 · External reference
Anti-Alzheimer Potential of a New (+)-Pinitol Glycoside Isolated from Tamarindus indica Pulp: In Vivo and In Silico Evaluations
10.3390/metabo13060732 · 2023 · External reference
Isolation and characterization of novel acetylcholinesterase inhibitors from Ficus benghalensis L. leaves
10.1039/d0ra06565j · 2020 · External reference
Free radical scavenging activity and total phenolic content of methanolic extracts from male inflorescence of Salix aegyptiaca grown in Iran
2010 · External reference
A Network Pharmacology Analysis of Cytotoxic Triterpenes Isolated from Euphorbia abyssinica Latex Supported by Drug-likeness and ADMET Studies
2022 · External reference
Network Pharmacological Analysis of the Red Sea Sponge Hyrtios erectus Extract to Reveal Anticancer Efficacy of Corresponding Loaded Niosomes
10.3390/md20100628 · 2022 · External reference
The DisGeNET knowledge platform for disease genomics: 2019 update
2020 · External reference
The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible
2016 · External reference
Cytoscape. js: a graph theory library for visualisation and analysis
10.1093/bioinformatics/btv557 · 2016 · External reference
ShinyGO: a graphical gene-set enrichment tool for animals and plants
10.1093/bioinformatics/btz931 · 2020 · External reference
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2020 · External reference
Effects of Momordica charantia L.(Cucurbitaceae) on indomethacin-induced ulcer model in rats
2005 · External reference
Mechanistic insights on the possible protective role of polyphenols extracted from Tamarix aphylla aerial parts against sodium arsenite-induced hepatotoxicity in rats
10.1007/s11356-022-23324-x · 2023 · External reference
Antihyperglycemic effect of methanol extract of Tamarix aphylla L. Karst (Saltcedar) in streptozocin–nicotinamide induced diabetic rats
10.1016/j.apjtb.2017.06.005 · 2017 · External reference
The production of acute gastric ulceration by indomethacin in the rats
1969 · External reference
Gastroprotective and antioxidant activity of Kalanchoe brasiliensis and Kalanchoe pinnata leaf juices against indomethacin and ethanol-induced gastric lesions in rats
10.3390/ijms19051265 · 2018 · External reference
Effects of propofol, midazolam and thiopental sodium on outcome and amino acids accumulation in focal cerebral ischemia-reperfusion in rats
2003 · External reference
Pathways of gastrointestinal protection and repair: mechanisms of action of sucralfate
10.1016/0002-9343(89)90153-8 · 1989 · External reference
Gastric antiulcer, antisecretory and cytoprotective properties of celery (Apium graveolens) in rats
10.3109/13880200903280026 · 2010 · External reference
Evaluation of antioxidant and anti-ulcerogenic effects of Eremurus persicus (Jaub & Spach) Boiss leaf hydroalcoholic extract on ethanol-induced gastric ulcer in rats
10.1007/s10787-021-00868-x · 2021 · External reference
Inhibition of lipide peroxidation in mitochondria by vitamin E
10.1016/0003-9861(59)90259-0 · 1959 · External reference
A spectrophotometric method for determination of reduced glutathione in tissues
1959 · External reference
Isolation and solubilization of proteins after TRIzol® extraction of RNA and DNA from patient material following prolonged storage
10.2144/000112401 · 2007 · External reference
Assessment of DNA yield and purity: an overlooked detail of PCR troubleshooting
10.1016/j.clinmicnews.2011.12.002 · 2012 · External reference
Analysis of relative gene expression data using real-time quantitative PCR and the 2− ΔΔCT method
10.1006/meth.2001.1262 · 2001 · External reference
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
10.1016/0003-2697(76)90527-3 · 1976 · External reference
Flavonoids of the flowers of Tamarix nilotica
10.1016/s0031-9422(00)80549-x · 1984 · External reference
Antipoliovirus flavonoids from Psiadia dentata
10.1177/095632020101200503 · 2001 · External reference
Chemical constituents of Tamarix chinensis
2014 · External reference
Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 expression by flavonoids isolated from Tanacetum microphyllum
10.1016/j.intimp.2006.08.012 · 2006 · External reference
Structure determination of monohydrated trifolin (kaempferol 3-O-β-D-galactopyranoside) from laboratory powder diffraction data
10.1002/jps.22379 · 2011 · External reference
Regiospecific synthesis of quercetin O-β-d-glucosylated and O-β-d-glucuronidated isomers
10.1016/j.tet.2011.03.110 · 2011 · External reference
Therapeutic Versus Preventative Use of Ginkgo biloba Extract (EGb 761) against Indomethacin-Induced Gastric Ulcer in Mice
10.3390/molecules27175598 · 2022 · External reference
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2019 · External reference
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2021 · External reference
Interleukin-13 Mediates Non-Steroidal Anti-Inflammatory-Drug-Induced Small Intestinal Mucosal Injury with Ulceration
10.3390/ijms241914971 · 2023 · External reference
The Interplay of Oxidative Stress and ROS Scavenging: Antioxidants as a Therapeutic Potential in Sepsis
2022 · External reference
Protective effect of coptisine free base on indomethacin-induced gastric ulcers in rats: Characterization of potential molecular mechanisms
10.1016/j.lfs.2017.12.004 · 2018 · External reference
Gastro-protective effects of Albizia anthelmintica leaf extract on indomethacin-induced gastric ulcer in wistar rats: In silico and in vivo Studies
10.3390/antiox10020176 · 2021 · External reference
Apple extract protects against indomethacin-induced gastric ulcers in rats by suppressing oxidative stress–The implication of Nrf-2/HO-1 signaling pathway: In silico and in vivo studies
10.1016/j.jff.2023.105926 · 2024 · External reference
Apium extract alleviates indomethacin-induced gastric ulcers in rats via modulating the VEGF and IK-κB/NF-κB p65 signaling pathway: insights from in silico and in vivo investigations
10.1186/s12906-023-04333-w · 2024 · External reference
Inflammatory microenvironment in gastric premalignant lesions: implication and application
10.3389/fimmu.2023.1297101 · 2023 · External reference
Traditional Chinese Medicine prescription Huang-Qi-Jian-Zhong-Tang ameliorates indomethacin-induced duodenal ulcers in rats by affecting NF-κB and STAT signaling pathways
10.1016/j.biopha.2022.113866 · 2022 · External reference
Piceatannol affects gastric ulcers induced by indomethacin: association of antioxidant, anti-inflammatory, and angiogenesis mechanisms in rats
10.3390/life12030356 · 2022 · External reference
Carnosic Acid Ameliorates Indomethacin-Induced Gastric Ulceration in Rats by Alleviating Oxidative Stress and Inflammation
10.3390/biomedicines11030829 · 2023 · External reference
The TNF-Alpha Inducing Protein is Associated With Gastric Inflammation and Hyperplasia in a Murine Model of Helicobacter pylori Infection
10.3389/fphar.2022.817237 · 2022 · External reference
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2022 · External reference
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2020 · External reference
Cyclooxygenase 2—implications on maintenance of gastric mucosal integrity and ulcer healing: controversial issues and perspectives
10.1136/gut.49.3.443 · 2001 · External reference
Anti-inflammatory and gastroprotective roles of rabdosia inflexa through downregulation of pro-inflammatory cytokines and MAPK/NF-κB signaling pathways
10.3390/ijms19020584 · 2018 · External reference
Involvement of MAPK/NF-κB signal transduction pathways: Camellia japonica mitigates inflammation and gastric ulcer
10.1016/j.biopha.2017.09.031 · 2017 · External reference
Protective Effects of Anwulignan against HCl/Ethanol-Induced Acute Gastric Ulcer in Mice
2021 · External reference
Dehydroevodiamine ameliorates indomethacin-induced gastric injury via inhibition of ERK and p38 signaling pathway
10.1016/j.phymed.2021.153764 · 2021 · External reference
Olmesartan niosomes ameliorates the Indomethacin-induced gastric ulcer in rats: Insights on MAPK and Nrf2/HO-1 signaling pathway
10.1007/s11095-021-03126-5 · 2021 · External reference
Indomethacin induces increase in gastric epithelial tight junction permeability via redistribution of occludin and activation of p38 MAPK in MKN-28 Cells
10.1080/21688370.2016.1187325 · 2016 · External reference
Anti-inflammatory effects of Weiyan I decoction against gastric ulcers in a rat model via inhibition of p38 mitogen-activated protein kinases signaling
2023 · External reference
Mechanisms of Dendrobium officinale polysaccharides in repairing gastric mucosal injuries based on mitogen-activated protein kinases (MAPK) signaling pathway
10.1080/21655979.2021.2006951 · 2022 · External reference
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