Research graph
References from Effect of an eight-week high-intensity interval training programme on circulating sphingolipid levels in middle-aged adults at elevated cardiometabolic risk (SphingoFIT)—Protocol for a randomised controlled exercise trial. Local targets link to admitted publications; unresolved targets remain external evidence.
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Unresolved reference
External reference
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New Cardiovascular Risk Assessment Techniques for Primary Prevention: JACC Review Topic of the Week
10.1016/j.jacc.2022.05.015 · 2022 · External reference
Lipid levels in patients hospitalized with coronary artery disease: an analysis of 136,905 hospitalizations in Get With The Guidelines
10.1016/j.ahj.2008.08.010 · 2009 · External reference
Innovative Approaches to Assess Intermediate Cardiovascular Risk Subjects: A Review From Clinical to Metabolomics Strategies.
2021 · External reference
Machine learning reveals serum sphingolipids as cholesterol-independent biomarkers of coronary artery disease
10.1172/jci131838 · 2020 · External reference
Sphingolipid Profiling: A Promising Tool for Stratifying the Metabolic Syndrome-Associated Risk.
2022 · External reference
Sphingolipids and their metabolism in physiology and disease
10.1038/nrm.2017.107 · 2018 · External reference
Too Much of a Good Thing? An Evolutionary Theory to Explain the Role of Ceramides in NAFLD.
2020 · External reference
The Lard Works in Mysterious Ways: Ceramides in Nutrition-Linked Chronic Disease
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Ceramides–Lipotoxic Inducers of Metabolic Disorders
10.1016/j.tem.2015.07.006 · 2015 · External reference
Why and how increased plasma ceramides predict future cardiovascular events?
10.1016/j.atherosclerosis.2020.09.030 · 2020 · External reference
Ceramides and other sphingolipids as drivers of cardiovascular disease.
10.1038/s41569-021-00536-1 · 2021 · External reference
Cholesterol—the devil you know; ceramide—the devil you don’t
10.1016/j.tips.2021.10.001 · 2021 · External reference
Editorial: The Role of Ceramides in Diabetes and Cardiovascular Disease.
2021 · External reference
Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol
10.1093/eurheartj/ehw148 · 2016 · External reference
Ceramide stearic to palmitic acid ratio predicts incident diabetes
10.1007/s00125-018-4590-6 · 2018 · External reference
Comparison of recent ceramide-based coronary risk prediction scores in cardiovascular disease patients
10.1093/eurjpc/zwab112 · 2021 · External reference
Absolute and relative risk prediction in cardiovascular primary prevention with a modified SCORE chart incorporating ceramide-phospholipid risk score and diabetes mellitus
10.1093/ehjopen/oeab010 · 2021 · External reference
Ceramides and Ceramide Scores: Clinical Applications for Cardiometabolic Risk Stratification.
10.3389/fendo.2020.570628 · 2020 · External reference
Ceramides and Phosphatidylcholines Associate with Cardiovascular Diseases in the Elderly
10.1093/clinchem/hvac158 · 2022 · External reference
Plasma ceramides and cardiac risk
10.1093/eurheartj/ehx205 · 2017 · External reference
An enhanced ceramide-based approach for primary prevention of atherosclerotic events
10.1093/ehjopen/oeab016 · 2021 · External reference
Exercise is the Real Polypill.
10.1152/physiol.00019.2013 · 2013 · External reference
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10.1249/jsr.0b013e318223cb10 · 2011 · External reference
World Health Organization 2020 guidelines on physical activity and sedentary behaviour
10.1136/bjsports-2020-102955 · 2020 · External reference
The HERITAGE Family Study: A Review of the Effects of Exercise Training on Cardiometabolic Health, with Insights into Molecular Transducers.
10.1249/mss.0000000000002859 · 2022 · External reference
Exercise benefits in cardiovascular disease: beyond attenuation of traditional risk factors.
10.1038/s41569-018-0065-1 · 2018 · External reference
High fatty acid availability after exercise alters the regulation of muscle lipid metabolism
10.1016/j.metabol.2010.08.004 · 2011 · External reference
Sphingolipid Metabolism and Signaling in Skeletal Muscle: From Physiology to Physiopathology.
2020 · External reference
The metabolic signature of cardiorespiratory fitness: a protocol for a systematic review and meta-analysis
10.1136/bmjsem-2020-001008 · 2021 · External reference
Importance of Assessing Cardiorespiratory Fitness in Clinical Practice: A Case for Fitness as a Clinical Vital Sign: A Scientific Statement From the American Heart Association
10.1161/cir.0000000000000461 · 2016 · External reference
Improved insulin sensitivity after exercise training is linked to reduced plasma C14:0 ceramide in obesity and type 2 diabetes
10.1002/oby.21117 · 2015 · External reference
High-Intensity Interval Training in Cardiac Rehabilitation.
10.1016/j.cger.2019.07.011 · 2019 · External reference
High-Intensity Interval Training for Patients With Cardiovascular Disease-Is It Safe?
10.1161/jaha.118.009305 · 2018 · External reference
Effects of high-intensity interval versus continuous exercise training on post-exercise heart rate recovery in coronary heart-disease patients
10.1016/j.ijcard.2017.06.067 · 2017 · External reference
Guidelines for the delivery and monitoring of high intensity interval training in clinical populations.
10.1016/j.pcad.2019.01.004 · 2019 · External reference
High-intensity interval training in patients with lifestyle-induced cardiometabolic disease: a systematic review and meta-analysis.
10.1136/bjsports-2013-092576 · 2014 · External reference
Update on the effects of physical activity on insulin sensitivity in humans.
10.1136/bmjsem-2016-000143 · 2017 · External reference
High-Intensity Interval Training for Cardiometabolic Disease Prevention.
10.1249/mss.0000000000001934 · 2019 · External reference
High-Intensity Interval Training Versus Moderate-Intensity Continuous Training in Middle-Aged and Older Patients with Type 2 Diabetes: A Randomized Controlled Crossover Trial of the Acute Effects of Treadmill Walking on Glycemic Control.
10.3390/ijerph16214163 · 2019 · External reference
High-Intensity Interval Training Interventions in Children and Adolescents: A Systematic Review.
10.1007/s40279-017-0753-8 · 2017 · External reference
Novel advances in shotgun lipidomics for biology and medicine
10.1016/j.plipres.2015.12.002 · 2016 · External reference
Lipidomics: Techniques, Applications, and Outcomes Related to Biomedical Sciences
10.1016/j.tibs.2016.08.010 · 2016 · External reference
Omic-Scale High-Throughput Quantitative LC-MS/MS Approach for Circulatory Lipid Phenotyping in Clinical Research
10.1021/acs.analchem.2c02598 · 2023 · External reference
SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials.
10.1136/bmj.e7586 · 2013 · External reference
Blocked randomization with randomly selected block sizes
10.3390/ijerph8010015 · 2011 · External reference
Development of the World Health Organization Global Physical Activity Questionnaire (GPAQ).
10.1007/s10389-006-0024-x · 2006 · External reference
Validation of the Global Physical Activity Questionnaire for self-administration in a European context.
10.1136/bmjsem-2016-000206 · 2017 · External reference
A new predictive equation for resting energy expenditure in healthy individuals
10.1093/ajcn/51.2.241 · 1990 · External reference
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10.1016/s0140-6736(11)60812-x · 2011 · External reference
Estimating changes in free-living energy intake and its confidence interval
10.3945/ajcn.111.014399 · 2011 · External reference
Insulin resistance index (HOMA-IR) levels in a general adult population: Curves percentile by gender and age. The EPIRCE study
10.1016/j.diabres.2011.07.015 · 2011 · External reference
Assessment of Body Composition in Health and Disease Using Bioelectrical Impedance Analysis (BIA) and Dual Energy X-Ray Absorptiometry (DXA): A Critical Overview.
10.1155/2019/3548284 · 2019 · External reference
Body composition by DXA
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Retinal vessel diameters and function in cardiovascular risk and disease
10.1016/j.preteyeres.2022.101095 · 2022 · External reference
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10.1016/s0161-6420(99)90525-0 · 1999 · External reference
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10.1016/j.ophtha.2003.09.039 · 2004 · External reference
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10.1016/j.atherosclerosis.2015.05.007 · 2015 · External reference
Expert consensus and evidence-based recommendations for the assessment of flow-mediated dilation in humans
10.1093/eurheartj/ehz350 · 2019 · External reference
Reference Intervals for Brachial Artery Flow-Mediated Dilation and the Relation With Cardiovascular Risk Factors
10.1161/hypertensionaha.120.15754 · 2021 · External reference
Mediterranean diet and endothelial function in patients with coronary heart disease: An analysis of the CORDIOPREV randomized controlled trial
10.1371/journal.pmed.1003282 · 2020 · External reference
Investigating the role of acute mental stress on endothelial dysfunction: a systematic review and meta-analysis
10.1007/s00392-014-0782-3 · 2015 · External reference
Intra-individual differences in the effect of endurance versus resistance training on vascular function: A cross-over study.
10.1111/sms.13975 · 2021 · External reference
Variability and reproducibility of flow-mediated dilatation in a multicentre clinical trial
10.1093/eurheartj/eht223 · 2013 · External reference
Reliability of measurement of endothelial function across multiple institutions and establishment of reference values in Japanese
10.1016/j.atherosclerosis.2015.08.001 · 2015 · External reference
Left atrial strain predicts incident atrial fibrillation in the general population: the Copenhagen City Heart Study
10.1093/ehjci/jeab202 · 2021 · External reference
Obesity and Atrial Fibrillation Prevalence, Pathogenesis, and Prognosis: Effects of Weight Loss and Exercise
10.1016/j.jacc.2017.09.002 · 2017 · External reference
Atrial fibrosis underlying atrial fibrillation (Review).
2021 · External reference
Influence of exercise training on the left atrium: implications for atrial fibrillation, heart failure, and stroke
10.1152/ajpheart.00322.2023 · 2023 · External reference
Guidelines for Performing a Comprehensive Transthoracic Echocardiographic Examination in Adults: Recommendations from the American Society of Echocardiography.
10.1016/j.echo.2018.06.004 · 2019 · External reference
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10.1093/ehjci/jey042 · 2018 · External reference
Superior Cardiovascular Effect of Aerobic Interval Training Versus Moderate Continuous Training in Heart Failure Patients
10.1161/circulationaha.106.675041 · 2007 · External reference
A Multi-Center Comparison of O2peak Trainability Between Interval Training and Moderate Intensity Continuous Training.
2019 · External reference
High Intensity Interval Training for Maximizing Health Outcomes.
10.1016/j.pcad.2017.03.006 · 2017 · External reference
High-intensity interval training modulates retinal microvascular phenotype and DNA methylation of p66Shc gene: a randomized controlled trial (EXAMIN AGE).
10.1093/eurheartj/ehz196 · 2019 · External reference
Hypertension and retinal microvascular dysfunction (HyperVasc): protocol of a randomised controlled exercise trial in patients with hypertension.
10.1136/bmjopen-2021-058997 · 2022 · External reference
How to Construct, Conduct and Analyze an Exercise Training Study?
10.3389/fphys.2018.01007 · 2018 · External reference
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10.1093/eurheartj/ehw106 · 2016 · External reference
Hexosylceramides as intrathecal markers of worsening disability in multiple sclerosis.
10.1177/1352458514561908 · 2015 · External reference
A comprehensive classification system for lipids
10.1194/jlr.e400004-jlr200 · 2005 · External reference
Update of the LIPID MAPS comprehensive classification system for lipids
10.1194/jlr.r800095-jlr200 · 2009 · External reference
Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures
10.1194/jlr.s120001025 · 2020 · External reference
Shorthand notation for lipid structures derived from mass spectrometry
10.1194/jlr.m033506 · 2013 · External reference
Metabolic View on Human Healthspan: A Lipidome-Wide Association Study.
10.3390/metabo11050287 · 2021 · External reference
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Robust causal inference using directed acyclic graphs: the R package ‘dagitty’.
2017 · External reference
A crash course in good and bad controls.
2020 · External reference
Oxygen uptake during mini trampoline exercise in normal-weight, endurance-trained adults and in overweight-obese, inactive adults: A proof-of-concept study
10.1080/17461391.2018.1449894 · 2018 · External reference
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10.1136/bmj.c332 · 2010 · External reference
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1994 · External reference
CERT2 ceramide- and phospholipid-based risk score and major adverse cardiovascular events: A systematic review and meta-analysis
10.1016/j.jacl.2022.02.001 · 2022 · External reference
