Research graph
References from Analysis of arsenic-modulated expression of hypothalamic estrogen receptor, thyroid receptor, and peroxisome proliferator-activated receptor gamma mRNA and simultaneous mitochondrial morphology and respiration rates in the mouse. Local targets link to admitted publications; unresolved targets remain external evidence.
A Comprehensive Review on Current Status, Mechanism, and Possible Sources of Arsenic Contamination in Groundwater: A Global Perspective with Prominence of Pakistan Scenario
10.1007/s10653-018-0169-x · 2019 · External reference
Towards Clean Water: Managing Risk of Arsenic-Contaminated Groundwater for Human Consumption
10.1016/j.coesh.2023.100509 · 2023 · External reference
A Cross-Sectional Study of Water Arsenic Exposure and Intellectual Function in Adolescence in Araihazar, Bangladesh
10.1016/j.envint.2018.05.037 · 2018 · External reference
Association of Arsenic Exposure and Cognitive Impairment: A Population-Based Cross-Sectional Study in China
10.1016/j.neuro.2020.11.009 · 2021 · External reference
Endocrine Disruptors and Thyroid Autoimmunity
10.1016/j.beem.2020.101377 · 2020 · External reference
Endocrine Disrupting Chemicals and Thyroid Cancer: An Overview
10.3390/toxics9010014 · 2021 · External reference
Endocrine Disruptors and Thyroid Hormone Physiology
10.1016/j.bcp.2009.11.006 · 2010 · External reference
Thyroid Effects of Endocrine Disrupting Chemicals
10.1016/j.mce.2011.09.005 · 2012 · External reference
Molecular Mechanism(s) of Endocrine-Disrupting Chemicals and Their Potent Oestrogenicity in Diverse Cells and Tissues That Express Oestrogen Receptors
10.1111/j.1582-4934.2012.01649.x · 2013 · External reference
Endocrine Disruption via Estrogen Receptors That Participate in Nongenomic Signaling Pathways
10.1016/j.jsbmb.2011.01.015 · 2011 · External reference
Endocrine Disrupting Chemicals Targeting Estrogen Receptor Signaling: Identification and Mechanisms of Action
10.1021/tx100231n · 2011 · External reference
A Review on Endocrine Disruptors and Their Possible Impacts on Human Health
10.1016/j.etap.2015.06.009 · 2015 · External reference
Challenges and Recommendations in Assessing Potential Endocrine‐Disrupting Properties of Metals in Aquatic Organisms
10.1002/etc.5741 · 2023 · External reference
Endocrine Equilibrium: Navigating the Hormonal Seas: Navigating the Whispers of Hormones: A Delicate Dance of Balance
2023 · External reference
Effects of Some Endocrine Disruptors on Cell Cycle Progression and Murine Dendritic Cell Differentiation
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Unresolved reference
2023 · External reference
Regulation of Energy Metabolism Pathways by Estrogens and Estrogenic Chemicals and Potential Implications in Obesity Associated with Increased Exposure to Endocrine Disruptors
10.1016/j.bbamcr.2009.03.009 · 2009 · External reference
Mitochondria as Target of Endocrine-Disrupting Chemicals: Implications for Type 2 Diabetes
10.1530/joe-18-0362 · 2018 · External reference
Impact of Metabolic Disrupting Chemicals on Redox Homeostasis, Energy Sensors, Receptor Modulation, and Hormone Metabolism: A Comparative Account in Teleost and Mammalian Model Organisms.
2023 · External reference
Arsenic and Human Health Effects: A Review
10.1016/j.etap.2015.09.016 · 2015 · External reference
Unresolved reference
2020 · External reference
Thyroid Hormone System Disrupting Chemicals
10.1016/j.beem.2021.101562 · 2021 · External reference
Thyroid Function Disruptors: From Nature to Chemicals
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The Influence of Peroxisome Proliferator-Activated Receptor γ (PPARγ) Ligands on Cancer Cell Tumorigenicity
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Arsenic Induces Sustained Impairment of Skeletal Muscle and Muscle Progenitor Cell Ultrastructure and Bioenergetics
10.1016/j.freeradbiomed.2014.06.012 · 2014 · External reference
Minireview: PPARγ as the Target of Obesogens
10.1016/j.jsbmb.2011.01.005 · 2011 · External reference
Ligand-Induced Changes in Oestrogen and Thyroid Hormone Receptor Expression in the Developing Rat Cerebellum: A Comparative Quantitative PCR and Western Blot Study
10.1556/avet.2012.023 · 2012 · External reference
Endocrine Disruptors Induced Distinct Expression of Thyroid and Estrogen Receptors in Rat versus Mouse Primary Cerebellar Cell Cultures
10.3390/brainsci9120359 · 2019 · External reference
Bisphenol a Influences Oestrogen- and Thyroid Hormone-Regulated Thyroid Hormone Receptor Expression in Rat Cerebellar Cell Culture
10.1556/004.2016.046 · 2016 · External reference
Comparison of Individual and Combined Effects of Four Endocrine Disruptors on Estrogen Receptor Beta Transcription in Cerebellar Cell Culture: The Modulatory Role of Estradiol and Triiodo-Thyronine
10.3390/ijerph13060619 · 2016 · External reference
Hypothalamic Regulation of Food Intake
2003 · External reference
The Neuroendocrine System: Organization and Homeostatic Role
2004 · External reference
10.1093/acprof:oso/9780199935734.001.0001
10.1093/acprof:oso/9780199935734.001.0001 · 2017 · External reference
Maintenance of Homeostasis in the Aging Hypothalamus: The Central and Peripheral Roles of Succinate. Front. Endocrinol
2015 · External reference
Energy Balance and Its Components: Implications for Body Weight Regulation
10.3945/ajcn.112.036350 · 2012 · External reference
Hypothalamic Circuits Regulating Appetite and Energy Homeostasis: Pathways to Obesity
10.1242/dmm.026609 · 2017 · External reference
Development and Function of the Blood-Brain Barrier in the Context of Metabolic Control
10.3389/fnins.2017.00224 · 2017 · External reference
Tanycytes: A Gateway to the Metabolic Hypothalamus
10.1111/jne.12191 · 2014 · External reference
Arcuate Nucleus-Dependent Regulation of Metabolism-Pathways to Obesity and Diabetes Mellitus
10.1210/endrev/bnab025 · 2022 · External reference
The Hypothalamus and Metabolism: Integrating Signals to Control Energy and Glucose Homeostasis
10.1016/j.coph.2013.09.010 · 2013 · External reference
AgRP/NPY and POMC Neurons in the Arcuate Nucleus and Their Potential Role in Treatment of Obesity
10.1016/j.ejphar.2021.174611 · 2022 · External reference
Mitochondrial Dynamics Controlled by Mitofusins Regulate Agrp Neuronal Activity and Diet-Induced Obesity
10.1016/j.cell.2013.09.004 · 2013 · External reference
Impact of Hypothalamic Reactive Oxygen Species in the Regulation of Energy Metabolism and Food Intake
10.3389/fnins.2015.00056 · 2015 · External reference
Setting the Tone: Reactive Oxygen Species and the Control of Appetitive Melanocortin Neurons
10.1016/j.cmet.2011.10.004 · 2011 · External reference
Regulation of Mitochondrial Respiratory Chain Biogenesis by Estrogens/Estrogen Receptors and Physiological, Pathological and Pharmacological Implications. Biochim. Biophys
2009 · External reference
Progesterone and Estrogen Regulate Oxidative Metabolism in Brain Mitochondria
10.1210/en.2007-1227 · 2008 · External reference
Thyroid Hormones and Mitochondria
10.1023/a:1016056905347 · 2002 · External reference
Thyroid Hormone Action in Mitochondria
10.1677/jme.0.0260067 · 2001 · External reference
Zearalenone as an Endocrine Disruptor in Humans
10.1016/j.etap.2016.10.015 · 2016 · External reference
The Imperceptible Contagion: Arsenic as a Neuro-Immune-Endocrine Disruptor
10.1007/s12595-021-00393-3 · 2021 · External reference
Estrogens and ICI182,780 (Faslodex) Modulate Mitosis and Cell Death in Immature Cerebellar Neurons via Rapid Activation of P44/P42 Mitogen-Activated Protein Kinase
10.1523/jneurosci.23-12-04984.2003 · 2003 · External reference
Comparative Analysis of Zearalenone Effects on Thyroid Receptor Alpha (TRα) and Beta (TRβ) Expression in Rat Primary Cerebellar Cell Cultures
2018 · External reference
Arsenic Round the World: A Review
10.1016/s0039-9140(02)00268-0 · 2002 · External reference
Arsenic-Induced Toxicity and the Protective Role of Ascorbic Acid in Mouse Testis
10.1016/j.taap.2006.11.009 · 2007 · External reference
Effects of Chronic Exposure to Sodium Arsenite on Hypothalamo-Pituitary-Testicular Activities in Adult Rats: Possible an Estrogenic Mode of Action
10.1186/1477-7827-4-9 · 2006 · External reference
Comparative Effects of Single Intraperitoneal or Oral Doses of Sodium Arsenate or Arsenic Trioxide during in Utero Development
10.1002/(sici)1096-9926(199911)60:5<283::aid-tera9>3.0.co;2-7 · 1999 · External reference
Unresolved reference
2012 · External reference
Arsenic Contamination of Groundwater: A Review of Sources, Prevalence, Health Risks, and Strategies for Mitigation
10.1155/2014/304524 · 2014 · External reference
Thyroid Hormone- and Estrogen Receptor Interactions with Natural Ligands and Endocrine Disruptors in the Cerebellum
10.1016/j.yfrne.2017.10.001 · 2018 · External reference
The Laboratory Rat: Relating Its Age with Human’s
2013 · External reference
Environmental and Occupational Exposure of Metals and Their Role in Male Reproductive Functions
10.3109/01480545.2012.710631 · 2013 · External reference
Dissimilar Anxiety-like Behavior in Prepubertal and Young Adult Female Rats on Acute Exposure to Aluminium
10.2174/1871524922666211231095507 · 2021 · External reference
Pre-Pubertal Stress and Brain Development in Rodents
10.1016/j.cobeha.2015.08.003 · 2016 · External reference
Assessment of Sex Specific Endocrine Disrupting Effects in the Prenatal and Pre-Pubertal Rodent Brain
10.1016/j.jsbmb.2015.08.021 · 2016 · External reference
Hypothalamic Sidedness in Mitochondrial Metabolism: New Perspectives
10.1177/1933719114530188 · 2014 · External reference
Preparation of Purified Perikaryal and Synaptosomal Mitochondrial Fractions from Relatively Small Hypothalamic Brain Samples
10.1016/j.mex.2016.05.004 · 2016 · External reference
Pregnancy Influences the Selection of Appropriate Reference Genes in Mouse Tissue: Determination of Appropriate Reference Genes for Quantitative Reverse Transcription PCR Studies in Tissues from the Female Mouse Reproductive Axis
10.1016/j.gene.2021.145855 · 2021 · External reference
Relative Expression Software Tool (REST) for Group-Wise Comparison and Statistical Analysis of Relative Expression Results in Real-Time PCR
10.1093/nar/30.9.e36 · 2002 · External reference
Ecto-Nucleoside Triphosphate Diphosphohydrolase 3 in the Ventral and Lateral Hypothalamic Area of Female Rats: Morphological Characterization and Functional Implications
2009 · External reference
CCN6 Regulates Mitochondrial Function
10.1242/jcs.186247 · 2016 · External reference
Environmental Arsenic Exposure and Its Toxicological Effect on Thyroid Function: A Systematic Review
10.1515/reveh-2021-0025 · 2022 · External reference
Mechanisms of Arsenic Disruption on Gonadal, Adrenal and Thyroid Endocrine Systems in Humans: A Review
10.1016/j.envint.2016.07.020 · 2016 · External reference
Mechanisms of Action of Arsenic Trioxide
2002 · External reference
Effects of Arsenite on Estrogen Receptor-α Expression Activity in MCF-7 Breast Cancer Cells
10.1210/endo.141.10.7704 · 2000 · External reference
Arsenic as an Endocrine Disruptor: Arsenic Disrupts Retinoic Acid Receptor- and Thyroid Hormone Receptor-Mediated Gene Regulation and Thyroid Hormone-Mediated Amphibian Tail Metamorphosis
10.1289/ehp.10131 · 2008 · External reference
Suppression of Cell Proliferation and Regulation of Estrogen Receptor α Signaling Pathway by Arsenic Trioxide on Human Breast Cancer MCF-7 Cells
10.1677/joe.0.1820325 · 2004 · External reference
Estrogen Signaling in Livers of Male Mice with Hepatocellular Carcinoma Induced by Exposure to Arsenic in Utero
10.1093/jnci/djh070 · 2004 · External reference
Arsenic Abrogates the Estrogen-Signaling Pathway in the Rat Uterus
10.1186/1477-7827-8-80 · 2010 · External reference
Central Nervous Control of Energy and Glucose Balance: Focus on the Central Melanocortin System
10.1111/j.1749-6632.2011.06248.x · 2011 · External reference
Bazedoxifene and Raloxifene Protect Neocortical Neurons Undergoing Hypoxia via Targeting ERα and PPAR-γ
10.1016/j.mce.2017.08.014 · 2018 · External reference
Functional Repression of Estrogen Receptor α by Arsenic Trioxide in Human Breast Cancer Cells
2002 · External reference
Biochemical and Molecular Alterations Following Arsenic-Induced Oxidative Stress and Mitochondrial Dysfunction in Rat Brain
10.1007/s12011-015-0284-9 · 2015 · External reference
Subchronic Exposure to Arsenic Represses the TH/TRβ1-CaMK IV Signaling Pathway in Mouse Cerebellum
10.3390/ijms17020157 · 2016 · External reference
Arsenic in Seafood Is Associated with Increased Thyroid-Stimulating Hormone (TSH) in Healthy Volunteers–A Randomized Controlled Trial
10.1016/j.jtemb.2017.05.004 · 2017 · External reference
Fish Arsenic May Influence Human Blood Arsenic, Selenium, and T4:T3 Ratio
10.1385/bter:90:1-3:83 · 2002 · External reference
Study of Distribution and Interaction of Arsenic and Selenium in Rat Thyroid
10.1007/bf02788967 · 1995 · External reference
Arsenic, Cadmium, and Lead Like Troglitazone Trigger PPARγ-Dependent Poly (ADP-Ribose) Polymerase Expression and Subsequent Apoptosis in Rat Brain Astrocytes
10.1007/s12035-017-0469-7 · 2018 · External reference
Arsenic Exposure Induces Glucose Intolerance and Alters Global Energy Metabolism
10.1152/ajpregu.00522.2016 · 2018 · External reference
Taurine Improves Low-Level Inorganic Arsenic-Induced Insulin Resistance by Activating PPARγ-MTORC2 Signalling and Inhibiting Hepatic Autophagy
10.1002/jcp.27318 · 2019 · External reference
Effects of Arsenic on Adipocyte Metabolism: Is Arsenic an Obesogen?
10.1016/j.mce.2017.05.008 · 2017 · External reference
Sodium Arsenite Inhibits and Reverses Expression of Adipogenic and Fat Cell-Specific Genes during in Vitro Adipogenesis
10.1093/toxsci/65.2.211 · 2002 · External reference
The Role of Akt on Arsenic Trioxide Suppression of 3T3-L1 Preadipocyte Differentiation
10.1038/sj.cr.7290305 · 2005 · External reference
Unraveling the Mechanism of Neuroprotection of Curcumin in Arsenic Induced Cholinergic Dysfunctions in Rats
10.1016/j.taap.2014.06.006 · 2014 · External reference
Encapsulation of the Flavonoid Quercetin with an Arsenic Chelator into Nanocapsules Enables the Simultaneous Delivery of Hydrophobic and Hydrophilic Drugs with a Synergistic Effect against Chronic Arsenic Accumulation and Oxidative Stress
10.1016/j.freeradbiomed.2011.08.019 · 2011 · External reference
MiADMSA Reverses Impaired Mitochondrial Energy Metabolism and Neuronal Apoptotic Cell Death after Arsenic Exposure in Rats
10.1016/j.taap.2011.04.004 · 2011 · External reference
Arsenic Toxicity and Potential Mechanisms of Action
10.1016/s0378-4274(02)00084-x · 2002 · External reference
Amelioration by Vitamin A upon Arsenic Induced Metabolic and Neurotoxic Effects
10.1248/jhs.52.568 · 2006 · External reference
Arsenic and Fluoride Induce Neural Progenitor Cell Apoptosis
10.1016/j.toxlet.2011.03.023 · 2011 · External reference
Arsenic Induced Neuronal Apoptosis in Guinea Pigs Is Ca2+ Dependent and Abrogated by Chelation Therapy: Role of Voltage Gated Calcium Channels
10.1016/j.neuro.2013.01.006 · 2013 · External reference
Arsenic Induces Reactive Oxygen Species-Caused Neuronal Cell Apoptosis through JNK/ERK-Mediated Mitochondria-Dependent and GRP 78/CHOP-Regulated Pathways
10.1016/j.toxlet.2013.10.013 · 2014 · External reference
Arsenic Trioxide-Induced Apoptosis Is Independent of CD95 in Lymphatic Cell Lines
2004 · External reference
Subchronic Exposure to Arsenic Decreased Sdha Expression in the Brain of Mice
10.1016/j.neuro.2009.04.011 · 2009 · External reference
Mechanistic View for Toxic Effects of Arsenic on Isolated Rat Kidney and Brain Mitochondria
2015 · External reference
Differential Effects of Estradiol, Raloxifene and Tamoxifen on Estrogen Receptor Expression in Cultured Human Skin Fibroblasts
2004 · External reference
Mitochondrial Effects of Estrogen Are Mediated by Estrogen Receptor α in Brain Endothelial Cells
10.1124/jpet.107.134072 · 2008 · External reference
Potential Interference of Aluminum Chlorohydrate with Estrogen Receptor Signaling in Breast Cancer Cells
2018 · External reference
Mitochondrial Dynamics in the Central Regulation of Metabolism
10.1038/nrendo.2014.160 · 2014 · External reference
During Autophagy Mitochondria Elongate, Are Spared from Degradation and Sustain Cell Viability
10.1038/ncb2220 · 2011 · External reference
Tubular Network Formation Protects Mitochondria from Autophagosomal Degradation during Nutrient Starvation
10.1073/pnas.1107402108 · 2011 · External reference
SLP‐2 Is Required for Stress‐induced Mitochondrial Hyperfusion
10.1038/emboj.2009.89 · 2009 · External reference
Regulation of OPA1 Processing and Mitochondrial Fusion by M-AAA Protease Isoenzymes and OMA1
10.1083/jcb.200906084 · 2009 · External reference
Inducible Proteolytic Inactivation of OPA1 Mediated by the OMA1 Protease in Mammalian Cells
10.1083/jcb.200906083 · 2009 · External reference
Formation and Disappearance of an Endogenous Uncoupling Factor during Swelling and Contraction of Mitochondria
10.1016/0006-3002(61)90600-x · 1961 · External reference
Electronic Microscopy Evidence for Mitochondria as Targets for Cd/Se/Te‐based Quantum Dot 705 Toxicity in Vivo
2012 · External reference
Arsenic-Induced Mitochondrial Oxidative Damage Is Mediated by Decreased PGC-1α Expression and Its Downstream Targets in Rat Brain
10.1016/j.cbi.2016.07.017 · 2016 · External reference
Inhibitory Effects of Selenium on Arsenic-Induced Anxiety-/Depression-Like Behavior and Memory Impairment
10.1007/s12011-021-02679-1 · 2022 · External reference
Subchronic Arsenic Exposure Induces Anxiety-Like Behaviors in Normal Mice and Enhances Depression-Like Behaviors in the Chemically Induced Mouse Model of Depression
2015 · External reference
Protective Effect of Gallic Acid against Arsenic-Induced Anxiety−/Depression- like Behaviors and Memory Impairment in Male Rats
10.1007/s11011-019-00432-1 · 2019 · External reference
Das Arsenic Induced Changes in Growth Development and Apoptosis in Neonatal and Adult Brain Cells in Vivo and in Tissue Culture
10.1016/s0378-4274(01)00535-5 · 2002 · External reference
Das Apoptosis and Necrosis in Developing Brain Cells Due to Arsenic Toxicity and Protection with Antioxidants
10.1016/s0378-4274(02)00282-5 · 2002 · External reference
Arsenic Induces Apoptosis in Mouse Liver Is Mitochondria Dependent and Is Abrogated by N-Acetylcysteine
10.1016/j.taap.2006.12.029 · 2007 · External reference
The Alteration of Mitochondria Is an Early Event of Arsenic Trioxide Induced Apoptosis in Esophageal Carcinoma Cells
2000 · External reference
