Research graph
References from Loss of the yeast transporter Agp2 upregulates the pleiotropic drug-resistant pump Pdr5 and confers resistance to the protein synthesis inhibitor cycloheximide. Local targets link to admitted publications; unresolved targets remain external evidence.
Molecular characterization of carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria in Saccharomyces cerevisiae and identification of a plasma membrane carnitine transporter, Agp2p
10.1093/emboj/18.21.5843 · 1999 · External reference
Yeast Agp2p and Agp3p function as amino acid permeases in poor nutrient conditions
10.1016/j.bbrc.2003.11.172 · 2004 · External reference
Amino acid signaling in Saccharomyces cerevisiae: a permease-like sensor of external amino acids and F-Box protein Grr1p are required for transcriptional induction of the AGP1 gene, which encodes a broad-specificity amino acid permease
10.1128/mcb.19.2.989 · 1999 · External reference
Carnitine uptake by AGP2 in yeast Saccharomyces cerevisiae is dependent on Hog1 MAP kinase pathway
10.1016/s1016-8478(23)15052-7 · 2002 · External reference
A Genome-Wide Screen in Saccharomyces cerevisiae Reveals Altered Transport As a Mechanism of Resistance to the Anticancer Drug Bleomycin
10.1158/0008-5472.can-03-2729 · 2004 · External reference
AGP2 encodes the major permease for high affinity polyamine import in Saccharomyces cerevisiae
10.1074/jbc.m503071200 · 2005 · External reference
Polyamine Uptake by DUR3 and SAM3 in Saccharomyces cerevisiae
10.1074/jbc.m611105200 · 2007 · External reference
Agp2, a member of the yeast amino acid permease family, positively regulates polyamine transport at the transcriptional level
10.1371/journal.pone.0065717 · 2013 · External reference
Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae
10.1111/1574-6976.12065 · 2014 · External reference
Constitutive and hyperresponsive signaling by mutant forms of Saccharomyces cerevisiae amino acid sensor Ssy1
10.1128/ec.2.5.922-929.2003 · 2003 · External reference
Ammonium permease-based sensing mechanism for rapid ammonium activation of the protein kinase A pathway in yeast
10.1111/j.1365-2958.2005.05043.x · 2006 · External reference
A split-ubiquitin two-hybrid screen for proteins physically interacting with the yeast amino acid transceptor Gap1 and ammonium transceptor Mep2
10.1371/journal.pone.0024275 · 2011 · External reference
The permease homologue Ssy1p controls the expression of amino acid and peptide transporter genes in Saccharomyces cerevisiae
10.1046/j.1365-2958.1998.00714.x · 1998 · External reference
Amino-acid-induced signalling via the SPS-sensing pathway in yeast
10.1042/bst0370242 · 2009 · External reference
The STK2 gene, which encodes a putative Ser/Thr protein kinase, is required for high-affinity spermidine transport in Saccharomyces cerevisiae
10.1128/mcb.17.6.2994 · 1997 · External reference
Regulation of yeast H(+)-ATPase by protein kinases belonging to a family dedicated to activation of plasma membrane transporters
10.1128/mcb.20.20.7654-7661.2000 · 2000 · External reference
Screening for modulators of spermine tolerance identifies Sky1, the SR protein kinase of Saccharomyces cerevisiae, as a regulator of polyamine transport and ion homeostasis
10.1128/mcb.21.1.175-184.2001 · 2001 · External reference
Deletions of SKY1 or PTK2 in the Saccharomyces cerevisiae trk1Deltatrk2Delta mutant cells exert dual effect on ion homeostasis
10.1016/s0006-291x(02)00823-9 · 2002 · External reference
The yeast SR protein kinase Sky1p modulates salt tolerance, membrane potential and the Trk1,2 potassium transporter
10.1016/s0005-2736(02)00503-5 · 2002 · External reference
Characterization of a transport and detoxification pathway for the antitumour drug bleomycin in Saccharomyces cerevisiae
10.1042/bj20040392 · 2004 · External reference
Complementation of the Yeast Model System Reveals that Caenorhabditis elegans OCT-1 Is a Functional Transporter of Anthracyclines
10.1371/journal.pone.0133182 · 2015 · External reference
The universal protein knowledgebase in 2023
10.1093/nar/gkac1052 · 2023 · External reference
The Yeast Permease Agp2 Senses Cycloheximide and Undergoes Degradation That Requires the Small Protein Brp1-Cellular Fate of Agp2 in Response to Cycloheximide
10.3390/ijms24086975 · 2023 · External reference
Guide to yeast genetics and molecular biology
1991 · External reference
Improved method for high efficiency transformation of intact yeast cells
10.1093/nar/20.6.1425 · 1992 · External reference
Unresolved reference
1987 · External reference
Disruption of the Saccharomyces cerevisiae cell-wall pathway gene SLG1 causes hypersensitivity to the antitumor drug bleomycin
10.1007/s00438-003-0812-8 · 2003 · External reference
The histone H2B Arg95 residue efficiently recruits the transcription factor Spt16 to mediate Ste5 expression of the pheromone response pathway
10.1038/s41598-023-37339-y · 2023 · External reference
GFP-based optimization scheme for the overexpression and purification of eukaryotic membrane proteins in Saccharomyces cerevisiae
10.1038/nprot.2008.44 · 2008 · External reference
Proteome-wide identification of ubiquitin interactions using UbIA-MS
10.1038/nprot.2017.147 · 2018 · External reference
Unresolved reference
2010 · External reference
STAR: ultrafast universal RNA-seq aligner
10.1093/bioinformatics/bts635 · 2013 · External reference
RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
2011 · External reference
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
2014 · External reference
Heavy-tailed prior distributions for sequence count data: removing the noise and preserving large differences
10.1093/bioinformatics/bty895 · 2019 · External reference
pheatmap: Pretty Heatmaps
2019 · External reference
dplyr: A Grammar of Data Manipulation. R package version 0.7. 6
2018 · External reference
10.1007/978-3-319-24277-4
10.1007/978-3-319-24277-4 · 2016 · External reference
Chromatin immunoprecipitation for determining the association of proteins with specific genomic sequences in vivo
10.1002/0471142727.mb2103s69 · 2005 · External reference
Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly available database
10.1002/pmic.200500358 · 2005 · External reference
Absolute yeast mitochondrial proteome quantification reveals trade-off between biosynthesis and energy generation during diauxic shift
10.1073/pnas.1918216117 · 2020 · External reference
Saccharomyces Genome Database: the genomics resource of budding yeast
10.1093/nar/gkr1029 · 2011 · External reference
Comprehensive temporal protein dynamics during the diauxic shift in Saccharomyces cerevisiae. Molecular &
10.1074/mcp.m114.045849 · 2015 · External reference
Do Multiple Drug Resistance Transporters Interfere with Cell Functioning under Normal Conditions?
10.1134/s0006297920120081 · 2020 · External reference
Yeast adaptation to 2, 4-dichlorophenoxyacetic acid involves increased membrane fatty acid saturation degree and decreased OLE1 transcription
10.1016/j.bbrc.2005.02.158 · 2005 · External reference
Org. sc. sgd. db: Genome wide annotation for yeast
2014 · External reference
TooT-SC: Predicting eleven substrate classes of transmembrane transport proteins
2022 · External reference
Aging-related elevation of sphingoid bases shortens yeast chronological life span by compromising mitochondrial function
10.18632/oncotarget.8195 · 2016 · External reference
The glyoxylate cycle and alternative carbon metabolism as metabolic adaptation strategies of Candida glabrata: perspectives from Candida albicans and Saccharomyces cerevisiae
2019 · External reference
Diverse RNA-binding proteins interact with functionally related sets of RNAs, suggesting an extensive regulatory system
10.1371/journal.pbio.0060255 · 2008 · External reference
The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs
10.1038/ncomms10127 · 2015 · External reference
Global analysis of yeast mRNPs. Nature Structural &
2013 · External reference
Regulation of transcriptome, translation, and proteome in response to environmental stress in fission yeast
10.1186/gb-2012-13-4-r25 · 2012 · External reference
The I-TASSER Suite: protein structure and function prediction
10.1038/nmeth.3213 · 2015 · External reference
Ubiquitin-dependent proteolysis in yeast cells expressing neurotoxic proteins
10.3389/fnmol.2015.00008 · 2015 · External reference
PubChem in 2021: new data content and improved web interfaces
10.1093/nar/gkaa971 · 2021 · External reference
Ubiquitin depletion as a key mediator of toxicity by translational inhibitors
10.1128/mcb.23.24.9251-9261.2003 · 2003 · External reference
Genetic separation of FK506 susceptibility and drug transport in the yeast Pdr5 ATP-binding cassette multidrug resistance transporter
10.1091/mbc.9.2.523 · 1998 · External reference
The pleitropic drug ABC transporters from Saccharomyces cerevisiae
2001 · External reference
PDR5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDR1
10.1016/s0021-9258(17)42155-7 · 1994 · External reference
Transcriptional control of the yeast PDR5 gene by the PDR3 gene product
1994 · External reference
The yeast zinc finger regulators Pdr1p and Pdr3p control pleiotropic drug resistance (PDR) as homo‐and heterodimers in vivo
10.1046/j.1365-2958.2002.03262.x · 2002 · External reference
Zinc cluster protein Rdr1p is a transcriptional repressor of the PDR5 gene encoding a multidrug transporter
10.1074/jbc.m201637200 · 2002 · External reference
Multiple signals from dysfunctional mitochondria activate the pleiotropic drug resistance pathway in Saccharomyces cerevisiae
10.1074/jbc.m007338200 · 2000 · External reference
Saccharomyces cerevisiae Multidrug Resistance Gene Expression Inversely Correlates with the Status of the F0Component of the Mitochondrial ATPase
10.1074/jbc.m106285200 · 2001 · External reference
RPD3 and UME6 are involved in the activation of PDR5 transcription and pleiotropic drug resistance in ρ 0 cells of Saccharomyces cerevisiae
10.1186/s12866-021-02373-1 · 2021 · External reference
