Research graph
References from Ninjin’yoeito reduces fatigue-like conditions by alleviating inflammation of the brain and skeletal muscles in aging mice. Local targets link to admitted publications; unresolved targets remain external evidence.
Fatigeue and aging.
10.1016/j.critrevonc.2003.07.003 · 2003 · External reference
Fatigue and the prediction of negative health outcomes: A systematic review with meta-analysis.
2021 · External reference
Anti-fatigue effect of hypericin in a chronic forced exercise mouse model
10.1016/j.jep.2021.114767 · 2022 · External reference
Establishment and identification of an animal model of long-term exercise-induced fatigue
2022 · External reference
An adrenalectomy mouse model reflecting clinical features for chronic fatigue syndrome.
2020 · External reference
ShenQi FuZheng Injection ameliorates fatigue-like behavior in mouse models of cancer-related fatigue.
10.1016/j.biopha.2019.01.042 · 2019 · External reference
Potential Role of Neuroactive Tryptophan Metabolites in Central Fatigue: Establishment of the Fatigue Circuit
2020 · External reference
Study on the Correlation Between NF-κB and Central Fatigue.
2021 · External reference
Molecular mechanisms of muscle fatigue
2021 · External reference
Brain interleukin-1β and the intrinsic receptor antagonist control peripheral toll-like receptor 3-mediated suppression of spontaneous activity in rats.
2014 · External reference
NLRP3 inflammasome activation mediates fatigue-like behaviors in mice via neuroinflammation
10.1016/j.neuroscience.2017.06.048 · 2017 · External reference
Induction of interleukin-1β byactivated microglia is a prerequisite for immunologically induced fatigue
10.1111/ejn.12668 · 2014 · External reference
IL-1/IL-1ra balance in the brain revisited–Evidence from transgenic mouse models
10.1016/j.bbi.2009.02.015 · 2009 · External reference
Role of brain IL-1β on fatigue after exercise-induced muscle damage
2006 · External reference
The effect of interleukin-1 blockade on fatigue in rheumatoid arthritis—A pilot study.
10.1007/s00296-004-0463-z · 2005 · External reference
Effect of low-intensity motor balance and coordination exercise on cognitive functions, hippocampal Aβ deposition, neuronal loss, neuroinflammation, and oxidative stress in a mouse model of Alzheimer’s disease
10.1016/j.expneurol.2020.113590 · 2021 · External reference
Effects of low-intensity exercise on spontaneously developed knee osteoarthritis in male senescence-accelerated mouse prone 8.
2023 · External reference
Analysis of the Effects of Ninjin’yoeito on Physical Frailty in Mice.
2022 · External reference
Anti-inflammatory diets and fatigue.
2019 · External reference
Neuroinflammation, Oxidative Stress, and Neurogenesis in a Mouse Model of Chronic Fatigue Syndrome, and the Treatment with Kampo Medicine
2020 · External reference
Anti-fatigue Effects of Active Ingredients from Traditional Chinese Medicine: A Review
10.2174/0929867324666170414164607 · 2017 · External reference
A Possibility of Simultaneous Treatment with the Multicomponent Drug, Ninjin’yoeito, for Anorexia, Apathy, and Cognitive Dysfunction in Frail Alzheimer’s Disease Patients: An Open-Label Pilot Study.
10.3233/adr-170026 · 2017 · External reference
Ren shen yangrong tang for fatigue in cancer survivors: A Phase I/II open-label study
10.1089/acm.2014.0211 · 2015 · External reference
Combined Use of Ninjin’yoeito Improves Subjective Fatigue Caused by Lenalidomide in Patients With Multiple Myeloma: A Retrospective Study.
2018 · External reference
Multifunctional Actions of Ninjinyoeito, a Japanese Kampo Medicine: Accumulated Scientific Evidence Based on Experiments With Cells and Animal Models, and Clinical Studies.
2018 · External reference
Herbal Medicine Ninjin’yoeito in the Treatment of Sarcopenia and Frailty.
2018 · External reference
Orange peel extract reduces the inflammatory state of skeletal muscle after downhill running via an increase in IL-1RA
10.1093/bbb/zbab049 · 2021 · External reference
Radix Polygalae extract exerts antidepressant effects in behavioral despair mice and chronic restraint stress-induced rats probably by promoting autophagy and inhibiting neuroinflammation
10.1016/j.jep.2020.113317 · 2021 · External reference
Pharmacokinetic study of Ninjin’yoeito: Absorption and brain distribution of Ninjin’yoeito ingredients in mice.
10.1016/j.jep.2021.114332 · 2021 · External reference
The treadmill fatigue test: A simple, high-throughput assay of fatigue-like behavior for the mouse
2016 · External reference
Neutrophil Depletion Attenuates Muscle Injury after Exhaustive Exercise.
10.1249/mss.0000000000000980 · 2016 · External reference
Korean red ginseng ameliorates fatigue via modulation of 5-ht and corticosterone in a sleep-deprived mouse model.
2021 · External reference
Anti-fatigue effect of quercetin on enhancing muscle function and antioxidant capacity
2021 · External reference
Biomarkers for chronic fatigue
10.1016/j.bbi.2012.06.006 · 2012 · External reference
Interleukin-1 as a mediator of fatigue in disease: A narrative review
2017 · External reference
Correction: Ligustilide improves aging-induced memory deficit by regulating mitochondrial related inflammation in SAMP8 mice [Aging.,
2019 · External reference
Neuroprotective effect of 1-Deoxynojirimycin on cognitive impairment, β-amyloid deposition, and neuroinflammation in the SAMP8 mice.
10.1016/j.biopha.2018.06.106 · 2018 · External reference
Protective effects of ginseng on neurological disorders.
2015 · External reference
Trans-cinnamaldehyde improves memory impairment by blocking microglial activation through the destabilization of iNOS mRNA in mice challenged with lipopolysaccharide
10.1016/j.neuropharm.2016.08.013 · 2016 · External reference
Tenuigenin protects dopaminergic neurons from inflammation via suppressing NLRP3 inflammasome activation in microglia.
2017 · External reference
Pro-resolving effect of ginsenosides as an anti-inflammatory mechanism of Panax ginseng.
2020 · External reference
Age and age-related diseases: Role of inflammation triggers and cytokines.
2018 · External reference
Human umbilical cord-derived mesenchymal stromal cells ameliorate aging-associated skeletal muscle atrophy and dysfunction by modulating apoptosis and mitochondrial damage in SAMP10 mice
2022 · External reference
In vivo alterations in skeletal muscle form and function after disuse atrophy
10.1249/mss.0b013e3181a645a6 · 2009 · External reference
The muscle protein synthetic response to food ingestion.
10.1016/j.meatsci.2015.05.009 · 2015 · External reference
Japanese Herbal Medicine Ninjinyoeito Mediates Its Orexigenic Properties Partially by Activating Orexin 1 Receptors.
2020 · External reference
Lactobacillus plantarum TWK10 supplementation improves exercise performance and increases muscle mass in mice.
2016 · External reference
Stimulation of functional recovery via neurorepair mechanisms by the traditional Japanese Kampo medicine, Ninjin’yoeito, and physical exercise in a rat ischemic stroke model
10.1016/j.jep.2022.115927 · 2023 · External reference
Mouse models of sarcopenia: classification and evaluation.
2021 · External reference
