Research graph
References from NMY-2, TOE-2 and PIG-1 regulate Caenorhabditis elegans asymmetric cell divisions. Local targets link to admitted publications; unresolved targets remain external evidence.
Mechanisms of asymmetric cell division: Two Bs or not two Bs, that is the question
10.1016/0092-8674(92)90468-r · 1992 · External reference
10.1101/504787
10.1101/504787 · 2018 · External reference
Polarized myosin produces unequal-size daughters during asymmetric cell division
10.1126/science.1196112 · 2010 · External reference
Developmental stage-dependent transcriptional regulatory pathways control neuroblast lineage progression.
10.1242/dev.098723 · 2013 · External reference
Caenorhabditis elegans PIG-1/MELK acts in a conserved PAR-4/LKB1 polarity pathway to promote asymmetric neuroblast divisions
10.1534/genetics.112.148106 · 2013 · External reference
The DEP domain-containing protein TOE-2 promotes apoptosis in the Q lineage of C. Elegans through two distinct mechanisms.
10.1242/dev.110486 · 2014 · External reference
MELK—a conserved kinase: functions, signaling, cancer, and controversy.
10.1186/s40169-014-0045-y · 2015 · External reference
PAR-4 and anillin regulate myosin to coordinate spindle and furrow position during asymmetric division
10.1083/jcb.201503006 · 2015 · External reference
The C. elegans MELK ortholog PIG-1 regulates cell size asymmetry and daughter cell fate in asymmetric neuroblast divisions
10.1242/dev.02447 · 2006 · External reference
PIG-1 MELK-dependent phosphorylation of nonmuscle myosin II promotes apoptosis through CES-1 Snail partitioning.
2020 · External reference
Programmed elimination of cells by caspase-independent cell extrusion in C. elegans
10.1038/nature11240 · 2012 · External reference
Multiple ERK substrates execute single biological processes in Caenorhabditis elegans germ-line development
10.1073/pnas.0812285106 · 2009 · External reference
DEP domains: structurally similar but functionally different
10.1038/nrm3791 · 2014 · External reference
Surprising similarities in structure comparison
10.1016/s0959-440x(96)80058-3 · 1996 · External reference
Highly accurate protein structure prediction with AlphaFold
10.1038/s41586-021-03819-2 · 2021 · External reference
AlphaFold Protein Structure Database: Massively expanding the structural coverage of protein-sequence space with high-accuracy models
10.1093/nar/gkab1061 · 2022 · External reference
Mitotic spindle positioning in the EMS cell of Caenorhabditis elegans requires LET-99 and LIN-5/NuMA.
10.1534/genetics.116.192831 · 2016 · External reference
LET-99 determines spindle position and is asymmetrically enriched in response to PAR polarity cues in C. elegans embryos
10.1242/dev.129.19.4469 · 2002 · External reference
A non-muscle myosin required for embryonic polarity in Caenorhabditis elegans
10.1038/382455a0 · 1996 · External reference
Cell Polarity Regulates Biased Myosin Activity and Dynamics during Asymmetric Cell Division via Drosophila Rho Kinase and Protein Kinase N
10.1016/j.devcel.2017.06.012 · 2017 · External reference
A spindle-independent cleavage furrow positioning pathway
10.1038/nature09334 · 2010 · External reference
Asymmetric cell division in the one-cell C. Elegans embryo: Multiple steps to generate cell size asymmetry.
2017 · External reference
The Genetics of Caenorhabditis elegans
10.1093/genetics/77.1.71 · 1974 · External reference
NMY-2 maintains cellular asymmetry and cell boundaries, and promotes a SRC-dependent asymmetric cell division
10.1016/j.ydbio.2009.12.041 · 2010 · External reference
Engineering the Caenorhabditis elegans genome using Cas9-triggered homologous recombination.
10.1038/nmeth.2641 · 2013 · External reference
A proneural gene controls C. elegans neuroblast asymmetric division and migration
10.1016/j.febslet.2014.02.036 · 2014 · External reference
Fiji: An open-source platform for biological-image analysis.
10.1038/nmeth.2019 · 2012 · External reference
MCMCglmm: MCMC Methods for Multi-Response GLMMs in R
2010 · External reference
Generalized linear mixed models: A review and some extensions.
10.1007/s10985-007-9065-x · 2007 · External reference
Generalized linear mixed models: a practical guide for ecology and evolution
10.1016/j.tree.2008.10.008 · 2009 · External reference
Emmeans: estimated marginal means [Internet]
2019 · External reference
Population Marginal Means in the Linear Model: An Alternative to Least Squares Means
10.1080/00031305.1980.10483031 · 1980 · External reference
Tidy Data
2014 · External reference
Unresolved reference
2010 · External reference
Post-embryonic cell lineages of the nematode, Caenorhabditis elegans
10.1016/0012-1606(77)90158-0 · 1977 · External reference
Antagonistic Behaviors of NMY-1 and NMY-2 Maintain Ring Channels in the C. elegans Gonad
10.1016/j.bpj.2016.10.011 · 2016 · External reference
Mechanical forces drive neuroblast morphogenesis and are required for epidermal closure
10.1016/j.ydbio.2016.02.023 · 2016 · External reference
Caenorhabditis elegans ced-3 caspase is required for asymmetric divisions that generate cells programmed to die
10.1534/genetics.118.301500 · 2018 · External reference
Re-visiting the principles of apicobasal polarity in Drosophila neural stem cells
10.1016/j.ydbio.2022.02.006 · 2022 · External reference
Actin-dependent membrane polarization reveals the mechanical nature of the neuroblast polarity cycle
10.1016/j.celrep.2021.109146 · 2021 · External reference
Drosophila nonmuscle myosin II promotes the asymmetric segregation of cell fate determinants by cortical exclusion rather than active transport
10.1016/s1534-5807(03)00359-9 · 2003 · External reference
