Research graph
References from Timing matters in the use of renin-angiotensin system modulators and COVID-related cognitive and cerebrovascular dysfunction. Local targets link to admitted publications; unresolved targets remain external evidence.
Neurologic Manifestations and Complications of COVID-19.
10.1146/annurev-med-042320-010427 · 2022 · External reference
COVID-19: from the structure and replication cycle of SARS-CoV-2 to its disease symptoms and treatment
2021 · External reference
Frequent neurocognitive deficits after recovery from mild COVID-19
10.1093/braincomms/fcaa205 · 2020 · External reference
Heart failure in COVID-19 patients: Critical care experience
10.5501/wjv.v11.i1.1 · 2022 · External reference
Comorbidities and the risk of severe or fatal outcomes associated with coronavirus disease 2019: A systematic review and meta-analysis
10.1016/j.ijid.2020.07.029 · 2020 · External reference
Hypertension and Excess Risk for Severe COVID-19 Illness Despite Booster Vaccination
10.1161/hypertensionaha.122.19694 · 2022 · External reference
Repressed Ang 1–7 in COVID-19 Is Inversely Associated with Inflammation and Coagulation.
10.1128/msphere.00220-22 · 2022 · External reference
Hypertension and COVID-19: Current Evidence and Perspectives.
10.1007/s40292-022-00506-9 · 2022 · External reference
COVID-19 and RAAS inhibitors: is there a final conclusion?
2021 · External reference
The Renin-Angiotensin System: A Key Role in SARS-CoV-2-Induced COVID-19.
10.3390/molecules26226945 · 2021 · External reference
GLP-1 receptor nitration contributes to loss of brain pericyte function in a mouse model of diabetes
2022 · External reference
SARS-CoV-2 downregulation of ACE2 and pleiotropic effects of ACEIs/ARBs.
10.1038/s41440-020-0488-z · 2020 · External reference
The pivotal link between ACE2 deficiency and SARS-CoV-2 infection: One year later
10.1016/j.ejim.2021.09.007 · 2021 · External reference
Angiotensin II and the fibroproliferative response to acute lung injury
10.1152/ajplung.00313.2002 · 2004 · External reference
Role of NADH/NADPH oxidase-derived H2O2 in angiotensin II-induced vascular hypertrophy
10.1161/01.hyp.32.3.488 · 1998 · External reference
The Angiotensin AT(2) Receptor: From a Binding Site to a Novel Therapeutic Target.
10.1124/pharmrev.120.000281 · 2022 · External reference
Acute and chronic angiotensin-(1–7) restores vasodilation and reduces oxidative stress in mesenteric arteries of salt-fed rats.
10.1152/ajpheart.00202.2011 · 2011 · External reference
an update
10.1016/s0167-0115(00)00138-5 · 2000 · External reference
Targeting the Protective Arm of the Renin-Angiotensin System: Focused on Angiotensin-(1–7).
10.1124/jpet.120.000397 · 2021 · External reference
Protective role of ACE2 and its downregulation in SARS-CoV-2 infection leading to Macrophage Activation Syndrome: Therapeutic implications
10.1016/j.lfs.2020.117905 · 2020 · External reference
Pathomechanism and Management of Stroke in COVID-19: Review of Immunopathogenesis, Coagulopathy, Endothelial Dysfunction, and Downregulation of ACE2.
10.3988/jcn.2021.17.2.155 · 2021 · External reference
SARS-CoV-2 Spike Protein Intensifies Cerebrovascular Complications in Diabetic hACE2 Mice through RAAS and TLR Signaling Activation.
10.3390/ijms242216394 · 2023 · External reference
COVID-19 and the role of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers
10.1177/1715163520929373 · 2020 · External reference
ACE-2/Ang1-7/Mas cascade mediates ACE inhibitor, captopril, protective effects in estrogen-deficient osteoporotic rats
10.1016/j.biopha.2017.05.062 · 2017 · External reference
Angiotensin-converting enzyme (ACE) 2 overexpression ameliorates glomerular injury in a rat model of diabetic nephropathy: a comparison with ACE inhibition.
2011 · External reference
Human intestine luminal ACE2 and amino acid transporter expression increased by ACE-inhibitors
10.1007/s00726-014-1889-6 · 2015 · External reference
Treatment with ACE inhibitors or ARBs and risk of severe/lethal COVID-19: a meta-analysis
10.1136/heartjnl-2020-317336 · 2020 · External reference
A systematic review and meta-analysis to evaluate the clinical outcomes in COVID-19 patients on angiotensin-converting enzyme inhibitors or angiotensin receptor blockers
10.1093/ehjcvp/pvaa064 · 2021 · External reference
Mortality and Severity in COVID-19 Patients on ACEIs and ARBs-A Systematic Review, Meta-Analysis, and Meta-Regression Analysis.
10.3389/fmed.2021.703661 · 2021 · External reference
Renin-Angiotensin System Inhibitors in Patients With COVID-19: A Meta-Analysis of Randomized Controlled Trials Led by the International Society of Hypertension.
10.1161/jaha.122.026143 · 2022 · External reference
Animal models for COVID-19
10.1038/s41586-020-2787-6 · 2020 · External reference