Research graph
References from Frailty and risk of systemic atherosclerosis: A bidirectional Mendelian randomization study. Local targets link to admitted publications; unresolved targets remain external evidence.
Management of frailty: opportunities, challenges, and future directions
10.1016/s0140-6736(19)31785-4 · 2019 · External reference
Frailty in elderly people
10.1016/s0140-6736(12)62167-9 · 2013 · External reference
Frailty in older adults: evidence for a phenotype
10.1093/gerona/56.3.m146 · 2001 · External reference
Disability and co-morbidity in relation to frailty: how much do they overlap?
10.1016/j.archger.2012.03.001 · 2012 · External reference
Frailty and Mortality Outcomes After Percutaneous Coronary Intervention: A Systematic Review and Meta-Analysis
10.1016/j.jamda.2017.09.002 · 2017 · External reference
Coronary Artery Disease in Patients ≥80 Years of Age
10.1016/j.jacc.2017.12.068 · 2018 · External reference
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
10.1038/s41588-018-0058-3 · 2018 · External reference
Prevalence and implications of frailty in acute stroke: systematic review & meta-analysis
10.1093/ageing/afac064 · 2022 · External reference
Prevalence of frailty in patients with lower extremity peripheral arterial disease: A systematic review and meta-analysis
10.1016/j.arr.2022.101748 · 2022 · External reference
Mendelian randomization”: can genetic epidemiology contribute to understanding environmental determinants of disease?
10.1093/ije/dyg070 · 2003 · External reference
Mendelian randomization: using genes as instruments for making causal inferences in epidemiology
10.1002/sim.3034 · 2008 · External reference
The frailty phenotype and the frailty index: different instruments for different purposes
10.1093/ageing/aft160 · 2014 · External reference
A Frailty Index for UK Biobank Participants
10.1093/gerona/gly094 · 2019 · External reference
A genome‐wide association study of the frailty index highlights brain pathways in ageing
10.1111/acel.13459 · 2021 · External reference
FinnGen provides genetic insights from a well-phenotyped isolated population
10.1038/s41586-022-05473-8 · 2023 · External reference
The UK Biobank resource with deep phenotyping and genomic data
10.1038/s41586-018-0579-z · 2018 · External reference
PhenoScanner: a database of human genotype-phenotype associations
10.1093/bioinformatics/btw373 · 2016 · External reference
PhenoScanner V2: an expanded tool for searching human genotype-phenotype associations
10.1093/bioinformatics/btz469 · 2019 · External reference
A review of instrumental variable estimators for Mendelian randomization
10.1177/0962280215597579 · 2017 · External reference
The MR-Base platform supports systematic causal inference across the human phenome
10.7554/elife.34408 · 2018 · External reference
Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator
10.1002/gepi.21965 · 2016 · External reference
Mendelian randomization study of telomere length and bone mineral density
10.18632/aging.202197 · 2020 · External reference
Multivariable Mendelian Randomization and Mediation
10.1101/cshperspect.a038984 · 2021 · External reference
A research agenda for ageing in China in the 21st century (2nd edition): Focusing on basic and translational research, long-term care, policy and social networks
10.1016/j.arr.2020.101174 · 2020 · External reference
Frailty and cardiovascular outcomes in the National Health and Aging Trends Study
10.1093/eurheartj/ehab468 · 2021 · External reference
Cardiovascular risk factors and frailty in a cross-sectional study of older people: implications for prevention
10.1093/ageing/afy080 · 2018 · External reference
Frailty status and cardiovascular disease risk profile in middle-aged and older females
10.1016/j.exger.2020.111061 · 2020 · External reference
Accumulation of Deficits as a Key Risk Factor for Cardiovascular Morbidity and Mortality: A Pooled Analysis of 154 000 Individuals
10.1161/jaha.119.014686 · 2020 · External reference
Frailty index as a predictor of all-cause and cause-specific mortality in a Swedish population-based cohort
10.18632/aging.101352 · 2017 · External reference
The impact of cardiovascular health and frailty on mortality for males and females across the life course
10.1186/s12916-022-02593-w · 2022 · External reference
Impact of frailty on all-cause mortality or major amputation in patients with lower extremity peripheral artery disease: A meta-analysis
10.1016/j.arr.2022.101656 · 2022 · External reference
Subclinical cardiovascular disease and risk of incident frailty: The British Regional Heart Study
10.1016/j.exger.2021.111522 · 2021 · External reference
Mediation of age in the association between frailty and large artery atherosclerosis burden—A population study in community-dwelling older adults
10.1016/j.jstrokecerebrovasdis.2020.104845 · 2020 · External reference
Atherosclerosis in frailty: Not frailty in atherosclerosis
10.1016/j.atherosclerosis.2017.09.014 · 2017 · External reference
Association of Triglyceride-Lowering LPL Variants and LDL-C-Lowering LDLR Variants With Risk of Coronary Heart Disease
10.1001/jama.2018.20045 · 2019 · External reference
The identification and prediction of frailty based on Bayesian network analysis in a community-dwelling older population
10.1186/s12877-022-03520-7 · 2022 · External reference
Total, LDL, and HDL cholesterol decrease with age in older men and women. The Rancho Bernardo Study 1984–1994
10.1161/01.cir.96.1.37 · 1997 · External reference