Research graph
References from Isolation and characterization of plant-derived exosome-like nanoparticles from Carica papaya L. fruit and their potential as anti-inflammatory agent. Local targets link to admitted publications; unresolved targets remain external evidence.
Plant‐derived exosome‐like nanoparticles: A concise review on its extraction methods, content, bioactivities, and potential as functional food ingredient
10.1111/1750-3841.15787 · 2021 · External reference
Plant-derived exosome-like nanoparticles and their therapeutic activities
10.1016/j.ajps.2021.05.006 · 2022 · External reference
Anti-inflammatory Properties of Ginseng-Derived Exosome-like Nanoparticles in LPS-induced RAW264.7.
2023 · External reference
Plant derived exosome- like Nanovesicles: an updated overview.
10.1016/j.plana.2022.100022 · 2023 · External reference
Onion (Allium cepa L.)-Derived Nanoparticles Inhibited LPS-Induced Nitrate Production, However, Their Intracellular Incorporation by Endocytosis Was Not Involved in This Effect On RAW 264 Cells.
10.3390/molecules26092763 · 2021 · External reference
Anti-inflammatory and antioxidant properties of unripe papaya extract in an excision wound model.
10.3109/13880209.2014.936470 · 2015 · External reference
Wound-healing potential of an ethanol extract of Carica papaya (Caricaceae) seeds.
10.1111/j.1742-481x.2011.00933.x · 2012 · External reference
Nutraceutical value of Carica papaya: A review.
2021 · External reference
Effects of acidified blanching water and pectinase enzyme pretreatments on physicochemical properties and antioxidant capacity of Carica papaya juice
10.1111/1750-3841.16097 · 2022 · External reference
Unresolved reference
2019 · External reference
Extracts of Mauritian Carica papaya (var. solo) protect SW872 and HepG2 cells against hydrogen peroxide induced oxidative stress
10.1007/s13197-017-2626-4 · 2017 · External reference
Plant-derived extracellular vesicles: a novel nanomedicine approach with advantages and challenges
10.1186/s12964-022-00889-1 · 2022 · External reference
Inflammation–Nature’s Way to Efficiently Respond to All Types of Challenges: Implications for Understanding and Managing “the Epidemic” of Chronic Diseases.
10.3389/fmed.2018.00316 · 2018 · External reference
Nitric oxide and cell viability in inflammatory cells: a role for NO in macrophage function and fate
10.1016/j.tox.2004.11.035 · 2005 · External reference
The Anti-Inflammatory Effects and Mechanisms of Eupafolin in Lipopolysaccharide-Induced Inflammatory Responses in RAW264.7 Macrophages.
10.1371/journal.pone.0158662 · 2016 · External reference
Inflammatory responses and inflammation-associated diseases in organs.
10.18632/oncotarget.23208 · 2017 · External reference
Anti-inflammatory and immunomodulatory properties of Carica papaya.
10.3109/1547691x.2016.1149528 · 2016 · External reference
10.1002/9781119288190
10.1002/9781119288190 · 2020 · External reference
Advancement of nanomedicines in chronic inflammatory disorders
10.1007/s10787-022-00927-x · 2022 · External reference
Characterization of the microRNA profile of ginger exosome-like nanoparticles and their anti-inflammatory effects in intestinal Caco-2 Cells
10.1021/acs.jafc.1c07306 · 2022 · External reference
Broccoli-derived nanoparticle inhibits mouse colitis by activating dendritic cell AMP-activated protein kinase
10.1016/j.ymthe.2017.01.025 · 2017 · External reference
Evaluation of Antioxidant Activity and Drug Delivery Potential of Cell-Derived Extracellular Vesicles from Citrus reticulata Blanco cv. ‘Dahongpao.
10.3390/antiox12091706 · 2023 · External reference
Isolation of Aloe saponaria-Derived Extracellular Vesicles and Investigation of Their Potential for Chronic Wound Healing.
10.3390/pharmaceutics14091905 · 2022 · External reference
The zebrafish as a model for complex tissue regeneration
10.1016/j.tig.2013.07.003 · 2013 · External reference
A novel dual-response chemosensor for bioimaging of Exogenous/Endogenous hypochlorite and hydrazine in living cells, Pseudomonas aeruginosa and zebrafish
10.1016/j.snb.2020.128450 · 2020 · External reference
Articaine in functional NLC show improved anesthesia and anti-inflammatory activity in zebrafish.
10.1038/s41598-020-76751-6 · 2020 · External reference
Molecular Actors of Inflammation and Their Signaling Pathways: Mechanistic Insights from Zebrafish
2023 · External reference
In vivo drug discovery in the zebrafish
10.1038/nrd1606 · 2005 · External reference
Zebrafish as a model to study inflammation: A tool for drug discovery
10.1016/j.biopha.2021.112310 · 2021 · External reference
Zebrafish as an early stage screening tool to study the systemic circulation of nanoparticulate drug delivery systems in vivo
10.1016/j.jconrel.2017.08.023 · 2017 · External reference
A cost-effective polyethylene glycol-based method for the isolation of functional edible nanoparticles from ginger rhizomes.
10.1038/s41598-020-61358-8 · 2020 · External reference
Characterizing Kaempferia parviflora extracellular vesicles, a nanomedicine candidate.
10.1371/journal.pone.0262884 · 2022 · External reference
Isolation Of Cabbage Exosome-Like Nanovesicles and Investigation of Their Biological Activities in Human Cells.
10.1016/j.bioactmat.2021.04.023 · 2021 · External reference
Mesenchymal Stem Cell Exosomes Induce Proliferation and Migration of Normal and Chronic Wound Fibroblasts, and Enhance Angiogenesis In Vitro
10.1089/scd.2014.0316 · 2015 · External reference
Down-regulation of complement genes in lipopolysaccharide-challenged zebrafish (Danio rerio) larvae exposed to Indonesian propolis.
2021 · External reference
Long‐lasting effects of dexamethasone on immune cells and wound healing in the zebrafish.
10.1111/wrr.12366 · 2015 · External reference
Endotoxin Molecule Lipopolysaccharide-Induced Zebrafish Inflammation Model: A Novel Screening Method for Anti-Inflammatory Drugs.
10.3390/molecules19022390 · 2014 · External reference
Liposomal Clodronate-mediated Macrophage Depletion in the Zebrafish Model.
10.21769/bioprotoc.3951 · 2021 · External reference
Macrophages inhibit Aspergillus fumigatus germination and neutrophil-mediated fungal killing.
10.1371/journal.ppat.1007229 · 2018 · External reference
Bioactivity of Phytosterols and Their Production in Plant in Vitro Cultures
10.1021/acs.jafc.6b02345 · 2016 · External reference
Identification of 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one as a strong antioxidant in glucose-histidine Maillard reaction products
10.1016/j.foodres.2012.12.044 · 2013 · External reference
Unresolved reference
2021 · External reference
Potential Role of Bioactive Phytochemicals in Combination Therapies against Antimicrobial Activity.
10.3831/kpi.2022.25.2.79 · 2022 · External reference
Bioactive variability and in vitro and in vivo antioxidant activity of unprocessed and processed flour of nine cultivars of Australian lupin species: A comprehensive substantiation.
10.3390/antiox9040282 · 2020 · External reference
Maltol, a Natural Flavor Enhancer, Inhibits NLRP3 and Non-Canonical Inflammasome Activation
10.3390/antiox11101923 · 2022 · External reference
Alkamides Activate Jasmonic Acid Biosynthesis and Signaling Pathways and Confer Resistance to Botrytis cinerea in Arabidopsis thaliana.
10.1371/journal.pone.0027251 · 2011 · External reference
Unresolved reference
2015 · External reference
Induction of apoptosis by fatty acid ethyl esters in HepG2 cells
10.1016/j.fct.2004.09.003 · 2005 · External reference
Unresolved reference
External reference
Ethyl Acetate Extract of Marine Algae, Halymenia durvillei, Provides Photoprotection against UV-Exposure in L929 and HaCaT Cells.
10.3390/md20110707 · 2022 · External reference
Anti-viral compounds from Jatropha curcas seed extract with anti-HIV-1 and anti-SARS-CoV-2 action
10.5897/ajpp2022.5328 · 2023 · External reference
Antifungal properties and mechanisms of three volatile aldehydes (octanal, nonanal and decanal) on Aspergillus flavus.
10.1016/j.gaost.2021.07.002 · 2021 · External reference
Bioactive Components and Health Potential of Endophytic Micro-Fungal Diversity in Medicinal Plants.
10.3390/antibiotics11111533 · 2022 · External reference
10.1142/8033
10.1142/8033 · 2011 · External reference
Nutrients and bioactive components from vinegar: A fermented and functional food.
10.1016/j.jff.2019.103681 · 2020 · External reference
An Overview of Piperazine Scaffold as Promising Nucleus for Different Therapeutic Targets.
10.2174/1381612826666200417154810 · 2020 · External reference
Study of chemical composition of Foeniculum vulgare using Fourier transform infrared spectrophotometer and gas chromatography—mass spectrometry
10.5897/jpp2015.0372 · 2016 · External reference
3,4-Dihydroxyacetophenone attenuates oxidative stress-induced damage to HUVECs via regulation of the Nrf2/HO-1 pathway.
10.3892/mmr.2022.12715 · 2022 · External reference
Synthesis of Dihydrobenzofuranone Derivatives with Biotechnological Methods
10.18596/jotcsa.448551 · 2018 · External reference
Quantitative Phytochemical Profile and In Vitro Antioxidant Properties of Ethyl Acetate Extracts of Xerophyta spekei (Baker) and Grewia tembensis (Fresen).
10.1177/2515690x231165096 · 2023 · External reference
Recent biological applications of heterocyclic hybrids containing s -triazine scaffold.
10.1039/d3ra05953g · 2023 · External reference
Oxygenated Cyclohexene Derivatives from the Stem and Root Barks of Uvaria pandensis
10.1021/acs.jnatprod.1c00811 · 2021 · External reference
Biological Importance of Phenol Derivatives as Potent Bioactive Compound: A Review.
10.2174/1570178614666171130155539 · 2018 · External reference
Carbamate group as structural motif in drugs: a review of carbamate derivatives used as therapeutic agents.
10.2478/aiht-2020-71-3466 · 2020 · External reference
The influence of carambola starfruit (Averrhoa bilimbi) and Papaya (Carica papaya) on the quality of the organoleptic properties, vitamin C content, and fiber at jelly candies.
10.1088/1755-1315/443/1/012017 · 2020 · External reference
The effect of nanoparticle size on in vivo pharmacokinetics and cellular interaction
10.2217/nnm.16.5 · 2016 · External reference
Characterization and optimization of polymer-polymer aqueous two-phase systems for the isolation and purification of CaCo2 cell-derived exosomes.
10.1371/journal.pone.0273243 · 2022 · External reference
The Emerging Role of Plant-Derived Exosomes-Like Nanoparticles in Immune Regulation and Periodontitis Treatment.
10.3389/fimmu.2022.896745 · 2022 · External reference
Plant Exosomal Vesicles: Perspective Information Nanocarriers in Biomedicine.
2022 · External reference
Impact of Particle Size and Polydispersity Index on the Clinical Applications of Lipidic Nanocarrier Systems.
10.3390/pharmaceutics10020057 · 2018 · External reference
Unresolved reference
2019 · External reference
Zeta Potential of Extracellular Vesicles: Toward Understanding the Attributes that Determine Colloidal Stability.
10.1021/acsomega.0c01582 · 2020 · External reference
Ginger: a representative material of herb-derived exosome-like nanoparticles.
10.3389/fnut.2023.1223349 · 2023 · External reference
Edible ginger-derived nanoparticles: A novel therapeutic approach for the prevention and treatment of inflammatory bowel disease and colitis-associated cancer
10.1016/j.biomaterials.2016.06.018 · 2016 · External reference
Apple-derived nanoparticles modulate expression of organic-anion-transporting polypeptide (OATP) 2B1 in Caco-2 cells.
10.1021/acs.molpharmaceut.8b00921 · 2018 · External reference
An Apple a Day Keeps the Doctor Away: Potential Role of miRNA 146 on Macrophages Treated with Exosomes Derived from Apples.
10.3390/biomedicines10020415 · 2022 · External reference
Targeted drug delivery to intestinal macrophages by bioactive nanovesicles released from grapefruit
10.1038/mt.2013.190 · 2014 · External reference
Plant-derived nanovesicles: Further exploration of biomedical function and application potential.
2023 · External reference
Trehalose prevents aggregation of exosomes and cryodamage.
10.1038/srep36162 · 2016 · External reference
Cryopreservation of Mesenchymal Stromal Cell-Derived Extracellular Vesicles Using Trehalose Maintains Their Ability to Expand Hematopoietic Stem Cells in Vitro
10.1016/j.cryobiol.2020.11.009 · 2021 · External reference
Comparison of two isolation methods of tobacco-derived extracellular vesicles, their characterization and uptake by plant and rat cells.
10.1038/s41598-022-23961-9 · 2022 · External reference
Stability of plant leaf-derived extracellular vesicles according to preservative and storage temperature.
10.3390/pharmaceutics14020457 · 2022 · External reference
Aloe derived nanovesicle as a functional carrier for indocyanine green encapsulation and phototherapy.
10.1186/s12951-021-01195-7 · 2021 · External reference
Comprehensive Assessment of Antioxidant and Anti-Inflammatory Properties of Papaya Extracts.
10.3390/foods11203211 · 2022 · External reference
Role of Antioxidants and Natural Products in Inflammation.
10.1155/2016/5276130 · 2016 · External reference
Antioxidant activity of papaya seed extracts against H2O2 induced oxidative stress in HepG2 cells
10.1016/j.lwt.2015.09.008 · 2016 · External reference
Effect of hydroxyl on antioxidant properties of 2,3-dihydro-3,5-dihydroxy-6-methyl-4 H -pyran-4-one to scavenge free radicals.
10.1039/d1ra06317k · 2021 · External reference
Bioactive Compounds and in vitro Antimicrobial Activities of Ethanol Stem Bark Extract of Trilepisium madagascariense DC
10.3923/ijp.2018.901.912 · 2018 · External reference
nalysis of trace heavy metals and volatile chemical compounds of Lepidium sativum using atomic absorption spectroscopy, gas chromatography-mass spectrometric and fourier-transform infrared spectroscopy
2016 · External reference
Mandal PK, Karthe P, Sadasivan C, Haridas M. Anti‐Inflammatory Property of n ‐Hexadecanoic Acid: Structural Evidence and Kinetic Assessment
10.1111/j.1747-0285.2012.01418.x · 2012 · External reference
5-Hydroxymethylfurfural Mitigates Lipopolysaccharide-Stimulated Inflammation via Suppression of MAPK, NF-κB and mTOR Activation in RAW 264.7 Cells.
10.3390/molecules24020275 · 2019 · External reference
Stigmasterol alleviates allergic airway inflammation and airway hyperresponsiveness in asthma mice through inhibiting substance-P receptor
10.1080/13880209.2023.2173252 · 2023 · External reference
Synthesis, Characterization, and Anti-Inflammatory Activities of Methyl Salicylate Derivatives Bearing Piperazine Moiety.
10.3390/molecules21111544 · 2016 · External reference
Routes and mechanisms of extracellular vesicle uptake.
10.3402/jev.v3.24641 · 2014 · External reference
A Phosphatidic Acid (PA) conveyor system of continuous intracellular transport from cell membrane to nucleus maintains EGF receptor homeostasis.
10.18632/oncotarget.9685 · 2016 · External reference
Balloon Flower Root-Derived Extracellular Vesicles: In Vitro Assessment of Anti-Inflammatory, Proliferative, and Antioxidant Effects for Chronic Wound Healing.
2023 · External reference
Anti-inflammatory properties of lemon-derived extracellular vesicles are achieved through the inhibition of ERK/NF-κB signalling pathways
10.1111/jcmm.17404 · 2022 · External reference
The Role of Inflammatory and Anti-Inflammatory Cytokines in the Pathogenesis of Osteoarthritis.
10.1155/2014/561459 · 2014 · External reference
Purification And Characterization of a Nitric Oxide Inhibitory Peptide from Ruditapes philippinarum
10.1016/j.fct.2012.02.021 · 2012 · External reference
Er-Miao-San, A Traditional Herbal Formula Containing Rhizoma Atractylodis and Cortex Phellodendri Inhibits Inflammatory Mediators In LPS-Stimulated RAW264. 7 Macrophages Through Inhibition Of NF-Κb Pathway and Mapks Activation
10.1016/j.jep.2014.04.042 · 2014 · External reference
Interspecies communication between plant and mouse gut host cells through edible plant derived exosome‐like nanoparticles
10.1002/mnfr.201300729 · 2014 · External reference
Attenuation of Lipopolysaccharide-Induced Inflammatory Responses through Inhibition of the NF-κB Pathway and the Increased NRF2 Level by a Flavonol-Enriched n -Butanol Fraction from Uvaria alba.
10.1021/acsomega.2c06451 · 2023 · External reference
Potential Cancer- and Alzheimer’s Disease-Targeting Phosphodiesterase Inhibitors from Uvaria alba: Insights from In Vitro and Consensus Virtual Screening.
10.1021/acsomega.1c00137 · 2021 · External reference
Glucocorticoid-induced attenuation of the inflammatory response in zebrafish
10.1210/en.2015-2050 · 2016 · External reference
Micrometam C protects against oxidative stress in inflammation models in zebrafish and RAW264. 7 macrophages.
10.3390/md13095593 · 2015 · External reference
Repositioning drugs for inflammatory disease–fishing for new anti-inflammatory agents.,.
2014 · External reference
Modeling inflammation in zebrafish for the development of anti-inflammatory drugs
10.3389/fcell.2020.620984 · 2021 · External reference
Characterization of ginsenoside extracts by delayed luminescence, high-performance liquid chromatography, and bioactivity tests.
10.1039/c8pp00533h · 2019 · External reference
Zebrafish as a model for the study of neutrophil biology
10.1189/jlb.1112594 · 2013 · External reference
Mpeg1 Promoter Transgenes Direct Macrophage-Lineage Expression in Zebrafish
10.1182/blood-2010-10-314120 · 2011 · External reference
Differential regulation of protrusion and polarity by PI (3) K during neutrophil motility in live zebrafish.
10.1016/j.devcel.2009.11.015 · 2010 · External reference
Zebrafish Drug-Repurposing Screen Reveals SGC-Dependent and SGC-Independent Pro-Inflammatory Activities of Nitric Oxide.
10.1371/journal.pone.0137286 · 2015 · External reference
TNF signaling and macrophages govern fin regeneration in zebrafish larvae
10.1038/cddis.2017.374 · 2017 · External reference
Distinct Inflammatory and Wound Healing Responses to Complex Caudal Fin Injuries of Larval Zebrafish.
10.7554/elife.45976 · 2019 · External reference
Damage-Induced Calcium Signaling and Reactive Oxygen Species Mediate Macrophage Activation in Zebrafish.
10.3389/fimmu.2021.636585 · 2021 · External reference
