References

Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.

2021 · External reference

Systemic therapy in cervical cancer: 30 years in review.

10.1016/j.critrevonc.2019.02.009 · 2019 · External reference

Cervical Cancer, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology.

10.6004/jnccn.2019.0001 · 2019 · External reference

Molecular mechanisms of epithelial-mesenchymal transition

10.1038/nrm3758 · 2014 · External reference

Upholding a role for EMT in breast cancer metastasis

10.1038/nature22816 · 2017 · External reference

The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer

10.1038/ncb3513 · 2017 · External reference

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

10.1038/ncb1998 · 2009 · External reference

m(6)A-induced lncRNA RP11 triggers the dissemination of colorectal cancer cells via upregulation of Zeb1.

10.1186/s12943-019-1014-2 · 2019 · External reference

Pleiotropic Roles for ZEB1 in Cancer.

10.1158/0008-5472.can-17-2476 · 2018 · External reference

Vascular endocan is preferentially expressed in tumor endothelium

10.1016/j.mvr.2006.05.010 · 2006 · External reference

Endocan expression and localization in human glioblastomas

10.1097/nen.0b013e3181a52a7f · 2009 · External reference

Advances in Understanding the Role of Aloe Emodin and Targeted Drug Delivery Systems in Cancer.

10.1155/2022/7928200 · 2022 · External reference

Aloe-emodin induced in vitro G2/M arrest of cell cycle in human promyelocytic leukemia HL-60 cells.

10.1016/j.fct.2004.03.002 · 2004 · External reference

Aloe-emodin-induced apoptosis in human gastric carcinoma cells.

10.1016/j.fct.2007.06.005 · 2007 · External reference

Emodin from Aloe Inhibits Porcine Reproductive and Respiratory Syndrome Virus via Toll-Like Receptor 3 Activation.

2021 · External reference

ESM1/HIF‑1alpha pathway modulates chronic intermittent hypoxia‑induced non‑small‑cell lung cancer proliferation, stemness and epithelial‑mesenchymal transition

10.3892/or.2020.7913 · 2021 · External reference

Validation of ESM1 Related to Ovarian Cancer and the Biological Function and Prognostic Significance

10.7150/ijbs.66839 · 2023 · External reference

Overexpression of endothelial cell specific molecule-1 (ESM-1) in gastric cancer.

10.1245/s10434-010-1037-9 · 2010 · External reference

ESM1 as a Marker of Macrotrabecular-Massive Hepatocellular Carcinoma.

10.1158/1078-0432.ccr-19-0859 · 2019 · External reference

STRING v10: protein-protein interaction networks, integrated over the tree of life

10.1093/nar/gku1003 · 2015 · External reference

Emt: 2016.

10.1016/j.cell.2016.06.028 · 2016 · External reference

Cervical cancer.

10.1016/s0140-6736(03)13778-6 · 2003 · External reference

EMT in cervical cancer: its role in tumour progression and response to therapy

10.1016/j.canlet.2014.09.021 · 2015 · External reference

Epithelial-mesenchymal transitions in development and disease

10.1016/j.cell.2009.11.007 · 2009 · External reference

ZEB1 promotes epithelial-mesenchymal transition in cervical cancer metastasis

10.1016/j.fertnstert.2015.03.016 · 2015 · External reference

ZEB1 serves as an oncogene in acute myeloid leukaemia via regulating the PTEN/PI3K/AKT signalling pathway by combining with P53

10.1111/jcmm.16539 · 2021 · External reference

Endocan expression and relationship with survival in human non–small cell lung cancer

10.1158/1078-0432.ccr-06-0185 · 2006 · External reference

Vascular endocan (ESM‐1) is markedly overexpressed in clear cell renal cell carcinoma.

10.1111/j.1365-2559.2009.03458.x · 2010 · External reference

ESM-1 is a novel human endothelial cell-specific molecule expressed in lung and regulated by cytokines

10.1074/jbc.271.34.20458 · 1996 · External reference

Endocan is a novel chondroitin sulfate/dermatan sulfate proteoglycan that promotes hepatocyte growth factor/scatter factor mitogenic activity

10.1074/jbc.m108395200 · 2001 · External reference

6-Gingerol stabilized the p-VEGFR2/VE-cadherin/beta-catenin/actin complex promotes microvessel normalization and suppresses tumor progression.

10.1186/s13046-019-1291-z · 2019 · External reference

Cartilage oligomeric matrix protein promotes epithelial-mesenchymal transition by interacting with transgelin in colorectal cancer

10.7150/thno.44456 · 2020 · External reference

Interaction between laminin-5gamma2 and integrin beta1 promotes the tumor budding of colorectal cancer via the activation of Yes-associated proteins

2019 · External reference

Transgelin Inhibits the Malignant Progression of Esophageal Squamous Cell Carcinomas by Regulating Epithelial–Mesenchymal Transition.

2021 · External reference

Emodin and aloe-emodin suppress breast cancer cell proliferation through ERα inhibition

2013 · External reference

Aloe-emodin suppresses esophageal cancer cell TE1 proliferation by inhibiting AKT and ERK phosphorylation.

10.3892/ol.2016.4910 · 2016 · External reference

In vitro and in vivo antileishmanial effects of aloe-emodin on Leishmania major

10.1016/j.jtcme.2014.11.004 · 2015 · External reference

Design, synthesis and anti-inflammatory evaluation of aloe-emodin derivatives as potential modulators of Akt, NF-kappaB and JNK signaling pathways

10.1016/j.ejmech.2022.114511 · 2022 · External reference

Antiviral activity of aloe-emodin against influenza A virus via galectin-3 up-regulation

10.1016/j.ejphar.2014.05.028 · 2014 · External reference

Anti-cancer effects of aloe-emodin: a systematic review.

2018 · External reference

Targeting ESM1/ VEGFalpha signaling axis: a promising therapeutic avenue for angiogenesis in cervical squamous cell carcinoma

10.7150/jca.84654 · 2023 · External reference

Endothelial cell-specific molecule 1 drives cervical cancer progression

10.1038/s41419-022-05501-5 · 2022 · External reference