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References from The evolutionarily conserved PhLP3 is essential for sperm development in Drosophila melanogaster. Local targets link to admitted publications; unresolved targets remain external evidence.
Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin
10.1016/s0092-8674(00)81376-8 · 1996 · External reference
An evolutionarily conserved gene required for proper microtubule architecture in Caenorhabditis elegans
10.1111/j.1356-9597.2004.00708.x · 2004 · External reference
The evolution and putative function of phosducin-like proteins in the malaria parasite Plasmodium
2013 · External reference
Characterization of a protozoan Phosducin-like protein-3 (PhLP-3) reveals conserved redox activity.
10.1371/journal.pone.0209699 · 2018 · External reference
Phosducin-like protein acts as a molecular chaperone for G protein betagamma dimer assembly
10.1038/sj.emboj.7600673 · 2005 · External reference
PhLP3 modulates CCT-mediated actin and tubulin folding via ternary complexes with substrates
10.1074/jbc.m513235200 · 2006 · External reference
Phosducin-like proteins in Dictyostelium discoideum: implications for the phosducin family of proteins
10.1093/emboj/cdg508 · 2003 · External reference
Function of phosducin-like proteins in G protein signaling and chaperone-assisted protein folding
10.1016/j.cellsig.2007.06.013 · 2007 · External reference
Regulatory interaction of phosducin-like protein with the cytosolic chaperonin complex
10.1073/pnas.112075699 · 2002 · External reference
Functional interaction between phosducin-like protein 2 and cytosolic chaperonin is essential for cytoskeletal protein function and cell cycle progression
10.1091/mbc.e07-01-0069 · 2007 · External reference
JPred4: a protein secondary structure prediction server
10.1093/nar/gkv332 · 2015 · External reference
Phosducin-Like Protein 3 is required for microtubule-dependent steps of cell division but not for meristem growth in Arabidopsis
10.1105/tpc.107.057737 · 2008 · External reference
Zebrafish information network, the knowledgebase for Danio rerio research
10.1093/genetics/iyac016 · 2022 · External reference
Structure of the complex between the cytosolic chaperonin CCT and phosducin-like protein
10.1073/pnas.0405070101 · 2004 · External reference
Search and sequence analysis tools services from EMBL-EBI in 2022
10.1093/nar/gkac240 · 2022 · External reference
Modulation of phosducin-like protein 3 (PhLP3) levels promotes cytoskeletal remodelling in a MAPK and RhoA-dependent manner.
10.1371/journal.pone.0028271 · 2011 · External reference
Snapshots of actin and tubulin folding inside the TRiC chaperonin
10.1038/s41594-022-00755-1 · 2022 · External reference
Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT
10.1016/j.cell.2022.11.014 · 2022 · External reference
Structural basis of plp2-mediated cytoskeletal protein folding by TRiC/CCT.
10.1126/sciadv.ade1207 · 2023 · External reference
FlyBase: updates to the Drosophila genes and genomes database
10.1093/genetics/iyad211 · 2024 · External reference
Diversity and dynamics of the Drosophila transcriptome
10.1038/nature12962 · 2014 · External reference
FlyAtlas 2: a new version of the Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
10.1093/nar/gkx976 · 2018 · External reference
Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly
10.1126/science.abk2432 · 2022 · External reference
Unresolved reference
1993 · External reference
Dynamics of spermiogenesis in Drosophila melanogaster. IV. Nuclear transformation.
10.1016/s0022-5320(74)80083-3 · 1974 · External reference
Dynamics of spermiogenesis in Drosophila melanogaster. I. Individualization process.
10.1007/bf00335253 · 1972 · External reference
A role for actin dynamics in individualization during spermatogenesis in Drosophila melanogaster.
2003 · External reference
Dynamics of spermiogenesis in Drosophila melanogaster. II. Coiling process.
10.1007/bf00306868 · 1972 · External reference
Highly accurate protein structure prediction with AlphaFold
10.1038/s41586-021-03819-2 · 2021 · External reference
AlphaFold Protein Structure Database in 2024: providing structure coverage for over 214 million protein sequences
10.1093/nar/gkad1011 · 2024 · External reference
Structure of the thioredoxin-fold domain of human phosducin-like protein 2.
10.1107/s1744309108037342 · 2009 · External reference
A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle
2023 · External reference
The thioredoxin superfamily in oxidative protein folding
10.1089/ars.2014.5849 · 2014 · External reference
SWISS-MODEL: homology modelling of protein structures and complexes
10.1093/nar/gky427 · 2018 · External reference
Substitution of the thioredoxin system for glutathione reductase in Drosophila melanogaster
10.1126/science.291.5504.643 · 2001 · External reference
The thioredoxin system of the malaria parasite Plasmodium falciparum. Glutathione reduction revisited
10.1074/jbc.m007633200 · 2000 · External reference
The ThioredoxinT and deadhead gene pair encode testis- and ovary-specific thioredoxins in Drosophila melanogaster
10.1007/s00412-003-0253-5 · 2003 · External reference
The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes
10.1534/genetics.104.026427 · 2004 · External reference
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
10.1242/dev.118.2.401 · 1993 · External reference
A discrete transcriptional silencer in the bam gene determines asymmetric division of the Drosophila germline stem cell
2003 · External reference
A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila
10.1038/nature05954 · 2007 · External reference
A New Family of Drosophila Balancer Chromosomes With a w− dfd-GMR Yellow Fluorescent Protein Marker
10.1534/genetics.106.063461 · 2006 · External reference
Type I repressors of P element mobility
10.1093/genetics/135.1.81 · 1993 · External reference
Germline sex determination regulates sex-specific signaling between germline stem cells and their niche
10.1016/j.celrep.2022.110620 · 2022 · External reference
Fiji: an open-source platform for biological-image analysis.
10.1038/nmeth.2019 · 2012 · External reference
Effects of co-exposure of benzene, toluene and xylene to Drosophila melanogaster: Alteration in hsp70, hsp60, hsp83, hsp26, ROS generation and oxidative stress markers.
10.1016/j.chemosphere.2010.01.054 · 2010 · External reference
Evaluation of potential reference genes for reverse transcription-qPCR studies of physiological responses in Drosophila melanogaster
10.1016/j.jinsphys.2011.03.014 · 2011 · External reference
Tracking Follicle Cell Development.
10.1007/978-1-0716-2970-3_8 · 2023 · External reference
Reduced Fertility of Drosophila melanogaster Hybrid male rescue (Hmr) Mutant Females Is Partially Complemented by Hmr Orthologs From Sibling Species.
10.1534/genetics.108.100057 · 2009 · External reference
Structures of the Gβ-CCT and PhLP1-Gβ-CCT complexes reveal a mechanism for G-protein β-subunit folding and Gβγ dimer assembly
10.1073/pnas.1419595112 · 2015 · External reference
PDCL2 is essential for spermiogenesis and male fertility in mice
10.1038/s41420-022-01210-2 · 2022 · External reference
PDCL2 is essential for sperm acrosome formation and male fertility in mice.
10.1111/andr.13329 · 2023 · External reference
Interaction of a Novel Chaperone PhLP2A With the Heat Shock Protein Hsp90
10.1002/jcb.25669 · 2017 · External reference
Thioredoxin-2 but not thioredoxin-1 is a substrate of thioredoxin peroxidase-1 from Drosophila melanogaster: isolation and characterization of a second thioredoxin in D. Melanogaster and evidence for distinct biological functions of Trx-1 and Trx-2
10.1074/jbc.m200636200 · 2002 · External reference
Structures of the germline-specific Deadhead and thioredoxin T proteins from Drosophila melanogaster reveal unique features among thioredoxins
10.1107/s2052252521000221 · 2021 · External reference
Thioredoxin and thioredoxin target proteins: from molecular mechanisms to functional significance
10.1089/ars.2011.4322 · 2013 · External reference
Cooperative action of antioxidant defense systems
10.1016/s0960-9822(01)00393-1 · 2001 · External reference
Protein disulfide isomerase: the structure of oxidative folding
10.1016/j.tibs.2006.06.001 · 2006 · External reference
Mutation in a structural gene for a beta-tubulin specific to testis in Drosophila melanogaster
10.1073/pnas.76.8.3991 · 1979 · External reference
Mutation in a testis-specific beta-tubulin in Drosophila: analysis of its effects on meiosis and map location of the gene
10.1016/0092-8674(80)90481-x · 1980 · External reference
The testis-specific beta-tubulin subunit in Drosophila melanogaster has multiple functions in spermatogenesis
10.1016/0092-8674(82)90321-x · 1982 · External reference
Genetic analysis of B2t, the structural gene for a testis-specific beta-tubulin subunit in Drosophila melanogaster
10.1093/genetics/105.2.345 · 1983 · External reference
Genetic analysis of microtubule structure: a beta-tubulin mutation causes the formation of aberrant microtubules in vivo and in vitro
10.1083/jcb.104.3.385 · 1987 · External reference
Mutations that encode partially functional beta 2 tubulin subunits have different effects on structurally different microtubule arrays
10.1083/jcb.107.1.141 · 1988 · External reference
Structurally similar Drosophila alpha-tubulins are functionally distinct in vivo
10.1091/mbc.8.3.481 · 1997 · External reference
Structural analysis of mutations in the Drosophila beta 2-tubulin isoform reveals regions in the beta-tubulin molecular required for general and for tissue-specific microtubule functions
10.1093/genetics/139.1.267 · 1995 · External reference
During Drosophila spermatogenesis beta 1, beta 2 and beta 3 tubulin isotypes are cell-type specifically expressed but have the potential to coassemble into the axoneme of transgenic flies
1991 · External reference
Drosophila spermiogenesis: Big things come from little packages.
10.4161/spmg.21798 · 2012 · External reference
The gammaTuRC components Grip75 and Grip128 have an essential microtubule-anchoring function in the Drosophila germline.
2006 · External reference
Yuri gagarin is required for actin, tubulin and basal body functions in Drosophila spermatogenesis
10.1242/jcs.026559 · 2008 · External reference
The Drosophila SUN protein Spag4 cooperates with the coiled-coil protein Yuri Gagarin to maintain association of the basal body and spermatid nucleus
10.1242/jcs.066589 · 2010 · External reference
Nuclear elongation during spermiogenesis depends on physical linkage of nuclear pore complexes to bundled microtubules by Drosophila Mst27D.
10.1371/journal.pgen.1010837 · 2023 · External reference
The Microtubule Cytoskeleton during the Early Drosophila Spermiogenesis.
10.3390/cells9122684 · 2020 · External reference
Genetic dissection of sperm individualization in Drosophila melanogaster.
1998 · External reference
Mulet (mlt) encodes a tubulin-binding cofactor E-like homolog required for spermatid individualization in Drosophila melanogaster.
10.4161/fly.21533 · 2012 · External reference
Tubulin-binding cofactor E-like (TBCEL), the protein product of the mulet gene, is required in the germline for the regulation of inter-flagellar microtubule dynamics during spermatid individualization.
10.1242/bio.049080 · 2020 · External reference
Separating from the pack: Molecular mechanisms of Drosophila spermatid individualization.
10.1080/21565562.2015.1041345 · 2015 · External reference
Mechanisms of spermiogenesis and spermiation and how they are disturbed.
10.4161/21565562.2014.979623 · 2014 · External reference
Actin binding proteins, spermatid transport and spermiation
10.1016/j.semcdb.2014.04.018 · 2014 · External reference
F-actin-based extensions of the head cyst cell adhere to the maturing spermatids to maintain them in a tight bundle and prevent their premature release in Drosophila testis
10.1186/1741-7007-7-19 · 2009 · External reference
A Single-Cell Transcriptome Atlas of the Aging Drosophila Brain
10.1016/j.cell.2018.05.057 · 2018 · External reference