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References from Preventive effects of a nutraceutical mixture of berberine, citrus and apple extracts on metabolic disturbances in Zucker fatty rats. Local targets link to admitted publications; unresolved targets remain external evidence.
Obesity: addressing a multifactorial disease
2004 · External reference
Ultra-processed foods and the development of obesity in adults
10.1038/s41430-022-01225-z · 2023 · External reference
Obesity: Epidemiology, Pathophysiology, and Therapeutics
10.3389/fendo.2021.706978 · 2021 · External reference
On behalf of the IARC working group on Energy Balance and Obesity, Energy balance and obesity: what are the main drivers?
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Adipose Tissue Dysfunction as Determinant of Obesity-Associated Metabolic Complications
10.3390/ijms20092358 · 2019 · External reference
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10.1007/s40273-014-0243-x · 2015 · External reference
Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults
10.1016/s0140-6736(17)32129-3 · 2017 · External reference
Experimental rat models to study the metabolic syndrome
10.1017/s0007114509990729 · 2009 · External reference
Obesity, Metabolic Syndrome, and Cardiovascular Disease
10.1210/jc.2004-0372 · 2004 · External reference
Metabolic Inflammation and Insulin Resistance in Obesity
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A clinical perspective of obesity, metabolic syndrome and cardiovascular disease
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Obesity and dyslipidemia
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Obesity, Insulin Resistance, and Type 2 Diabetes: Associations and Therapeutic Implications
10.2147/dmso.s275898 · 2020 · External reference
The relationship between obesity and hypertension: an updated comprehensive overview on vicious twins
10.1038/hr.2017.75 · 2017 · External reference
Multi-omics approaches for precision obesity management
2023 · External reference
Unresolved reference
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Nutraceuticals and the Network of Obesity Modulators
10.3390/nu14235099 · 2022 · External reference
Berberine, a Herbal Metabolite in the Metabolic Syndrome: The Risk Factors, Course, and Consequences of the Disease
10.3390/molecules27041351 · 2022 · External reference
Adipose tissue as a possible therapeutic target for polyphenols: A case for Cyclopia extracts as anti-obesity nutraceuticals
10.1016/j.biopha.2019.109439 · 2019 · External reference
Citrus aurantium L. polymethoxyflavones promote thermogenesis of brown and white adipose tissue in high-fat diet induced C57BL/6J mice
10.1016/j.jff.2020.103860 · 2020 · External reference
Apple polyphenols induce browning of white adipose tissue
10.1016/j.jnutbio.2019.108299 · 2020 · External reference
Nutraceuticals and Their Contribution to Preventing Noncommunicable Diseases
10.3390/foods12173262 · 2023 · External reference
Recent Advances in Nutraceuticals for the Treatment of Sarcopenic Obesity
10.3390/nu15173854 · 2023 · External reference
Appetite-Suppressing and Satiety-Increasing Bioactive Phytochemicals: A Systematic Review
10.3390/nu11092238 · 2019 · External reference
Nutraceuticals and Herbal Food Supplements for Weight Loss: Is There a Prebiotic Role in the Mechanism of Action?
10.3390/microorganisms9122427 · 2021 · External reference
Berberine, a potential prebiotic to indirectly promote Akkermansia growth through stimulating gut mucin secretion
10.1016/j.biopha.2021.111595 · 2021 · External reference
Efficacy and Safety of Nutrient Supplements for Glycaemic Control and Insulin Resistance in Type 2 Diabetes: An Umbrella Review and Hierarchical Evidence Synthesis
10.3390/nu14112295 · 2022 · External reference
A nutraceutical combination improves insulin sensitivity in patients with metabolic syndrome
10.4330/wjc.v4.i3.77 · 2012 · External reference
10.1016/b978-0-12-805417-8.00028-7
10.1016/b978-0-12-805417-8.00028-7 · 2018 · External reference
Nutraceutical agents with anti-inflammatory properties prevent dietary saturated-fat induced disturbances in blood–brain barrier function in wild-type mice
10.1186/1742-2094-10-73 · 2013 · External reference
Nutraceuticals: Focus on Anti-Inflammatory, Anti-Cancer, Antioxidant Properties in Gastrointestinal Tract
10.3390/antiox11071274 · 2022 · External reference
Hesperidin: A Therapeutic Agent For Obesity
10.2147/dddt.s227499 · 2019 · External reference
Citrus peel extracts attenuated obesity and modulated gut microbiota in mice with high-fat diet-induced obesity
10.1039/c7fo02066j · 2018 · External reference
Apple-Derived Pectin Modulates Gut Microbiota, Improves Gut Barrier Function, and Attenuates Metabolic Endotoxemia in Rats with Diet-Induced Obesity
10.3390/nu8030126 · 2016 · External reference
Antihyperlipidemic effects of apple peel extract in high-fat diet-induced hyperlipidemic rats
10.4103/japtr.japtr_28_20 · 2020 · External reference
Development of insulin resistance and hyperphagia in Zucker fatty rats
10.1152/ajpregu.00428.2004 · 2006 · External reference
Insulin resistance in the Zucker diabetic fatty rat: a metabolic characterisation of obese and lean phenotypes
10.1007/s00592-005-0197-8 · 2005 · External reference
Relaxation of corpus cavernosum and raised intracavernous pressure by berberine in rabbit: Berberine relaxes corpus cavernosum
10.1038/sj.bjp.0702249 · 1998 · External reference
Validation of HOMA-IR in a model of insulin-resistance induced by a high-fat diet in Wistar rats
10.1590/2359-3997000000169 · 2016 · External reference
Sildenafil citrate long-term treatment effects on cardiovascular reactivity in a SHR experimental model of metabolic syndrome
10.1371/journal.pone.0223914 · 2019 · External reference
Evaluation of general 16S ribosomal RNA gene PCR primers for classical and next-generation sequencing-based diversity studies
10.1093/nar/gks808 · 2013 · External reference
Dadaist2: A Toolkit to Automate and Simplify Statistical Analysis and Plotting of Metabarcoding Experiments
10.3390/ijms22105309 · 2021 · External reference
Spirulina Liquid Extract Protects against Fibrosis Related to Non-Alcoholic Steatohepatitis and Increases Ursodeoxycholic Acid
10.3390/nu11010194 · 2019 · External reference
Nonlinear mixed effects models applied to cumulative concentration–response curves
10.1211/jpp.62.03.0008 · 2010 · External reference
Hepatic lesions induced by feeding Western diets to Zucker fatty rats, an insulin-resistant model
10.1293/tox.2018-0016 · 2018 · External reference
Pepsin Egg White Hydrolysate Improves Glucose Metabolism Complications Related to Metabolic Syndrome in Zucker Fatty Rats
10.3390/nu10040441 · 2018 · External reference
Berberine regulates UCP1 expression by reshaping the conformation of quadruplex formed by the element of the UCP1 gene promoter
10.3724/abbs.2022155 · 2022 · External reference
Antihyperlipidemic effects of Citrus sinensis, Citrus paradisi, and their combinations
10.4103/0975-7406.171727 · 2016 · External reference
Effect of Berberine on Atherosclerosis and Gut Microbiota Modulation and Their Correlation in High-Fat Diet-Fed ApoE−/− Mice
10.3389/fphar.2020.00223 · 2020 · External reference
Polyphenols from Olive-Mill Wastewater and Biological Activity: Focus on Irritable Bowel Syndrome
10.3390/nu14061264 · 2022 · External reference
Short-Chain Fatty Acids Decrease the Frequency of Spontaneous Contractions of Longitudinal Muscle via Enteric Nerves in Rat Distal Colon
10.2170/jjphysiol.54.483 · 2004 · External reference
Short chain fatty acids and colon motility in a mouse model of irritable bowel syndrome
10.1186/s12876-021-01613-y · 2021 · External reference
Red wine extract preserves tight junctions in intestinal epithelial cells under inflammatory conditions: implications for intestinal inflammation
10.1039/c8fo02469c · 2019 · External reference
Polyphenols and Intestinal Permeability: Rationale and Future Perspectives
10.1021/acs.jafc.9b02283 · 2020 · External reference
Polyphenol-Rich Propolis Extracts Strengthen Intestinal Barrier Function by Activating AMPK and ERK Signaling
10.3390/nu8050272 · 2016 · External reference
Obesity and Endothelial Function
10.3390/biomedicines10071745 · 2022 · External reference
Mechanisms of endothelial dysfunction in obesity-associated hypertension
10.1590/s0100-879x2012007500058 · 2012 · External reference
Vascular Lipotoxicity: Endothelial Dysfunction via Fatty-Acid-Induced Reactive Oxygen Species Overproduction in Obese Zucker Diabetic Fatty Rats
10.1210/en.2006-1132 · 2007 · External reference
Age-dependent changes in blood pressure and arterial reactivity in obese Zucker rats
10.1016/j.ejphar.2003.08.003 · 2003 · External reference
Selective resistance to vasoactive effects of insulin in muscle resistance arteries of obese Zucker (fa / fa) rats
10.1152/ajpendo.00516.2006 · 2007 · External reference
The Vascular Consequences of Metabolic Syndrome: Rodent Models, Endothelial Dysfunction, and Current Therapies
10.3389/fphar.2020.00148 · 2020 · External reference
Wild blueberry consumption affects aortic vascular function in the obese Zucker rat
10.1139/apnm-2013-0249 · 2014 · External reference
Effects of berberine and metformin on intestinal inflammation and gut microbiome composition in db/db mice
10.1016/j.biopha.2019.109131 · 2019 · External reference
Bile Acids and Short-Chain Fatty Acids Are Modulated after Onion and Apple Consumption in Obese Zucker Rats
10.3390/nu15133035 · 2023 · External reference
Recent findings in Akkermansia muciniphila-regulated metabolism and its role in intestinal diseases
10.1016/j.clnu.2022.08.029 · 2022 · External reference
Short-chain fatty acids-producing probiotics: A novel source of psychobiotics
10.1080/10408398.2021.1920884 · 2022 · External reference
The role of short-chain fatty acids in the interplay between gut microbiota and diet in cardio-metabolic health
10.1080/19490976.2021.1897212 · 2021 · External reference