Research graph
References from Effects of in utero delta-9-tetrahydrocannabinol (THC) exposure on fetal and infant musculoskeletal development in a preclinical nonhuman primate model. Local targets link to admitted publications; unresolved targets remain external evidence.
An Introduction to the Endogenous Cannabinoid System
10.1016/j.biopsych.2015.07.028 · 2016 · External reference
Targeting Cannabinoid CB2 Receptors in the Central Nervous System. Medicinal Chemistry Approaches with Focus on Neurodegenerative Disorders.
10.3389/fnins.2016.00406 · 2016 · External reference
Update on the controversial identity of cells expressing cnr2 gene in the nervous system
10.1111/cns.13977 · 2023 · External reference
CB2 receptor in the CNS: From immune and neuronal modulation to behavior
10.1016/j.neubiorev.2023.105226 · 2023 · External reference
An overview of the cannabinoid type 2 receptor system and its therapeutic potential
10.1097/aco.0000000000000616 · 2018 · External reference
Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli
10.1111/j.1471-4159.2005.03380.x · 2005 · External reference
Review of the Endocannabinoid System.
2021 · External reference
Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System.
2018 · External reference
Endocannabinoid signaling in synaptic function
10.1002/glia.24256 · 2023 · External reference
Human CB1 Receptor Isoforms, present in Hepatocytes and beta-cells, are Involved in Regulating Metabolism.
10.1038/srep33302 · 2016 · External reference
The role of the endocannabinoid system in skeletal muscle and metabolic adaptations to exercise: potential implications for the treatment of obesity.
10.1111/j.1467-789x.2012.01026.x · 2012 · External reference
The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels
10.1073/pnas.1406728111 · 2014 · External reference
Delta(9)-Tetrahydrocannabinol acts as a partial agonist/antagonist in mice.
10.1097/fbp.0b013e32835a7c4d · 2012 · External reference
Cannabinoids and Cannabinoid Receptors: The Story so Far.
10.1016/j.isci.2020.101301 · 2020 · External reference
The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin
10.1038/sj.bjp.0707442 · 2008 · External reference
(-)-Delta9-tetrahydrocannabinol antagonizes the peripheral cannabinoid receptor-mediated inhibition of adenylyl cyclase.
10.1074/jbc.271.17.9902 · 1996 · External reference
Cannabinoids and the expanded endocannabinoid system in neurological disorders.
10.1038/s41582-019-0284-z · 2020 · External reference
Delta 9-tetrahydrocannabinol: a novel treatment for experimental autoimmune encephalomyelitis
10.1016/0165-5728(89)90075-1 · 1989 · External reference
The major plant-derived cannabinoid Delta(9)-tetrahydrocannabinol promotes hypertrophy and macrophage infiltration in adipose tissue.
10.1055/s-0031-1297940 · 2012 · External reference
Antinociceptive and Immune Effects of Delta-9-Tetrahydrocannabinol or Cannabidiol in Male Versus Female Rats with Persistent Inflammatory Pain
10.1124/jpet.119.263319 · 2020 · External reference
Chronic prenatal delta-9-tetrahydrocannabinol exposure adversely impacts placental function and development in a rhesus macaque model
10.1038/s41598-022-24401-4 · 2022 · External reference
Cannabinoid receptors and their role in the regulation of the serotonin transporter in human placenta
10.1016/s0002-9378(99)70583-1 · 1999 · External reference
Fetal cannabinoid receptors and the "dis-joint-ed" brain.
10.1002/embj.201488086 · 2014 · External reference
Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research
10.1371/journal.pbio.1000412 · 2010 · External reference
Unresolved reference
2011 · External reference
The effects of delta-9-tetrahydrocannabinol exposure on female menstrual cyclicity and reproductive health in rhesus macaques.
2021 · External reference
Chronic exposure to delta-9-tetrahydrocannabinol impacts testicular volume and male reproductive health in rhesus macaques
10.1016/j.fertnstert.2021.12.028 · 2022 · External reference
Unresolved reference
External reference
Unresolved reference
External reference
mRNA transcript quantification in archival samples using multiplexed, color-coded probes
10.1186/1472-6750-11-46 · 2011 · External reference
Comparison of Nanostring nCounter(R) Data on FFPE Colon Cancer Samples and Affymetrix Microarray Data on Matched Frozen Tissues.
10.1371/journal.pone.0153784 · 2016 · External reference
Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool
10.1186/1471-2105-14-128 · 2013 · External reference
Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
10.1093/nar/gkw377 · 2016 · External reference
Gene Set Knowledge Discovery with Enrichr.
10.1002/cpz1.90 · 2021 · External reference
The STRING database in 2023: protein-protein association networks and functional enrichment analyses for any sequenced genome of interest
10.1093/nar/gkac1000 · 2023 · External reference
A convenient method for quantifying collagen fibers in atherosclerotic lesions by ImageJ software.
2017 · External reference
Fiji: an open-source platform for biological-image analysis.
10.1038/nmeth.2019 · 2012 · External reference
Hippocampal differential expression underlying the neuroprotective effect of delta-9-tetrahydrocannabinol microdose on old mice.
10.3389/fnins.2023.1182932 · 2023 · External reference
RNA-seq Analysis of delta9-Tetrahydrocannabinol-treated T Cells Reveals Altered Gene Expression Profiles That Regulate Immune Response and Cell Proliferation
10.1074/jbc.m116.719179 · 2016 · External reference
The Potential Use of Cannabis in Tissue Fibrosis.
10.3389/fcell.2021.715380 · 2021 · External reference
Self-reported Medical and Nonmedical Cannabis Use Among Pregnant Women in the United States
10.1001/jama.2019.7982 · 2019 · External reference
PI3K-PKB/Akt pathway.
10.1101/cshperspect.a011189 · 2012 · External reference
Regulation of PI3K/Akt/GSK-3 pathway by cannabinoids in the brain
10.1111/j.1471-4159.2007.04642.x · 2007 · External reference
PI3 kinase regulation of skeletal muscle hypertrophy and atrophy
2010 · External reference
Significance of Interleukin (IL)-4 and IL-13 in Inflammatory Arthritis.
10.3390/cells10113000 · 2021 · External reference
Role of interleukin 10 transcriptional regulation in inflammation and autoimmune disease
10.1615/critrevimmunol.v32.i1.30 · 2012 · External reference
Interleukin-24 Immunobiology and Its Roles in Inflammatory Diseases.
10.3390/ijms23020627 · 2022 · External reference
Role of Inflammation in Muscle Homeostasis and Myogenesis.
10.1155/2015/805172 · 2015 · External reference
Inverse regulation of protein turnover and amino acid transport in skeletal muscle of hypercatabolic patients
10.1210/jcem.87.7.8699 · 2002 · External reference
The physical and biological characterization of a frail mouse model
10.1093/gerona/63.4.391 · 2008 · External reference
Maternal Marijuana Use and Adverse Neonatal Outcomes: A Systematic Review and Meta-analysis.
10.1097/aog.0000000000001649 · 2016 · External reference
Association of Mental Health Burden With Prenatal Cannabis Exposure From Childhood to Early Adolescence: Longitudinal Findings From the Adolescent Brain Cognitive Development (ABCD) Study.
10.1001/jamapediatrics.2022.3191 · 2022 · External reference
Birth Outcomes of Neonates Exposed to Marijuana in Utero: A Systematic Review and Meta-analysis
10.1001/jamanetworkopen.2021.45653 · 2022 · External reference
Cannabis Use and Perinatal Health Research
10.1001/jama.2023.14697 · 2023 · External reference
Cannabis Use in Pregnancy and Neonatal Outcomes: A Systematic Review and Meta-Analysis.
2023 · External reference
Targeting Cannabinoid Receptors: Current Status and Prospects of Natural Products.
2020 · External reference
