Research graph
References from Induction of cell death by sodium hexachloroplatinate (IV) in the HEI-OC1 cell line, primary rat spiral ganglion cells and rat organ of Corti explants. Local targets link to admitted publications; unresolved targets remain external evidence.
Cochlear Implantation
2020 · External reference
Molecular and cellular mechanisms of loss of residual hearing after cochlear implantation
10.1177/000348941312200107 · 2013 · External reference
The importance of electrode location in cochlear implantation
10.1002/lio2.42 · 2016 · External reference
Spontaneous increases in impedance following cochlear implantation: suspected causes and management
10.1080/14992020802600808 · 2009 · External reference
Electron microscopy changes of cochlear implant electrodes with permanently high impedances
10.1179/1754762810y.0000000007 · 2011 · External reference
Biomedical studies on temporal bones of the first multi-channel cochlear implant patient at the University of Melbourne
10.1179/1754762814y.0000000087 · 2014 · External reference
Scanning electron microscopy of chronically implanted intracortical microelectrode arrays in non-human primates
10.1088/1741-2560/13/2/026003 · 2016 · External reference
Electrical stimulation with Pt electrodes: Trace analysis for dissolved platinum and other dissolved electrochemical products
10.1159/000124611 · 1977 · External reference
Electrical stimulation of excitable tissue: design of efficacious and safe protocols
10.1016/j.jneumeth.2004.10.020 · 2005 · External reference
Coulometric detection of irreversible electrochemical reactions occurring at Pt microelectrodes used for neural stimulation
10.1021/ac103037u · 2011 · External reference
Inhibition of cell division in Escherichia coli by electrolysis products from a platinum electrode
10.1038/205698a0 · 1965 · External reference
Chronic intracochlear electrical stimulation at high charge densities results in platinum dissolution but not neural loss or functional changes in vivo
10.1088/1741-2552/aaf66b · 2019 · External reference
Platinum dissolution and tissue response following long-term electrical stimulation at high charge densities
10.1088/1741-2552/abe5ba · 2021 · External reference
Cellular immunologic responses to cochlear implantation in the human
10.1016/j.heares.2014.09.007 · 2014 · External reference
Foreign Body Response to Silicone in Cochlear Implant Electrodes in the Human
10.1097/mao.0000000000001454 · 2017 · External reference
Electrical neurostimulation with imbalanced waveform mitigates dissolution of platinum electrodes
10.1088/1741-2560/13/5/054001 · 2016 · External reference
The inhibition of growth or cell division in Escherichia coli by different ionic species of platinum(IV) complexes
10.1016/s0021-9258(18)96186-7 · 1967 · External reference
Aminoglycoside- and Cisplatin-Induced Ototoxicity: Mechanisms and Otoprotective Strategies
10.1101/cshperspect.a033548 · 2019 · External reference
Cisplatin-induced ototoxicity: From signaling network to therapeutic targets
10.1016/j.biopha.2022.114045 · 2023 · External reference
Platinum corrosion products from electrode contacts of human cochlear implants induce cell death in cell culture models
10.1371/journal.pone.0196649 · 2018 · External reference
HEI-OC1 cells as a model for investigating drug cytotoxicity
10.1016/j.heares.2016.02.019 · 2016 · External reference
In vitro impact of platinum nanoparticles on inner ear related cell culture models
10.1371/journal.pone.0284794 · 2023 · External reference
Neurite outgrowth on cultured spiral ganglion neurons induced by erythropoietin
10.1016/j.heares.2008.07.003 · 2008 · External reference
p27Kip1 down-regulation as achieved by two clinically feasible means did not induce proliferation of supporting cells in the rat neonatal cochlea in vivo
10.1016/j.heares.2018.12.002 · 2019 · External reference
Brain-derived neurotrophic factor/glial cell line-derived neurotrophic factor survival effects on auditory neurons are not limited by dexamethasone
10.1097/00001756-200512190-00008 · 2005 · External reference
Analysis of cell death by electron microscopy
10.1007/978-1-62703-383-1_7 · 2013 · External reference
Visualization of Necroptotic Cell Death through Transmission Electron Microscopy
10.1007/978-1-0716-1162-3_12 · 2021 · External reference
BDNF-induced survival of auditory neurons in vivo: Cessation of treatment leads to accelerated loss of survival effects
10.1002/jnr.10542 · 2003 · External reference
Possible role of gap junction intercellular channels and connexin 43 in satellite glial cells (SGCs) for preservation of human spiral ganglion neurons: A comparative study with clinical implications
10.1007/s00441-013-1735-2 · 2014 · External reference
Schwann Cells: Development and Role in Nerve Repair
10.1101/cshperspect.a020487 · 2015 · External reference
Polymer Coatings of Cochlear Implant Electrode Surface—An Option for Improving Electrode-Nerve-Interface by Blocking Fibroblast Overgrowth
10.1371/journal.pone.0157710 · 2016 · External reference
Active role of glia-like supporting cells in the organ of Corti: Membrane proteins and their roles in hearing
10.1002/glia.24229 · 2022 · External reference
Supporting Cells and Their Potential Roles in Cisplatin-Induced Ototoxicity
10.3389/fnins.2022.867034 · 2022 · External reference
Inner ear supporting cells protect hair cells by secreting HSP70
10.1172/jci68480 · 2013 · External reference
Heat shock protein-mediated protection against Cisplatin-induced hair cell death
10.1007/s10162-014-0491-7 · 2015 · External reference
Cellular response to oxidative stress: signaling for suicide and survival
10.1002/jcp.10119 · 2002 · External reference
Axonal maintenance, glia, exosomes, and heat shock proteins
10.12688/f1000research.7247.1 · 2016 · External reference
Evaluating protective and therapeutic effects of alpha-lipoic acid on cisplatin-induced ototoxicity
10.1038/s41419-018-0888-z · 2018 · External reference
Ferrostatin-1 protects auditory hair cells from cisplatin-induced ototoxicity in vitro and in vivo
10.1016/j.bbrc.2020.10.019 · 2020 · External reference
Inhibition of ferroptosis protects House Ear Institute-Organ of Corti 1 cells and cochlear hair cells from cisplatin-induced ototoxicity
10.1111/jcmm.15839 · 2020 · External reference
Nrf2 Knockout Affected the Ferroptosis Signaling Pathway against Cisplatin-Induced Hair Cell-Like HEI-OC1
2022 · External reference
Role of neurotrophins and lectins in prevention of ototoxicity
10.1111/j.1749-6632.1999.tb08651.x · 1999 · External reference
Arrest of apoptosis in auditory neurons: implications for sensorineural preservation in cochlear implantation
10.1097/00129492-200305000-00011 · 2003 · External reference
Assessing cisplatin-induced ototoxicity and otoprotection in whole organ culture of the mouse inner ear in simulated microgravity
10.1016/j.toxlet.2014.03.022 · 2014 · External reference
Dexamethasone Protects Against Apoptotic Cell Death of Cisplatin-exposed Auditory Hair Cells In Vitro
10.1097/mao.0000000000000849 · 2015 · External reference
Mechanisms of cell uptake and toxicity of the anticancer drug cisplatin
10.1039/c4mt00238e · 2014 · External reference
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
10.1021/acs.chemrev.5b00597 · 2016 · External reference
In vitro skin permeation of potassium hexachloroplatinate and a comparison with potassium tetrachloroplatinate
10.1016/j.toxlet.2023.04.007 · 2023 · External reference
Lung function changes in mice sensitized to ammonium hexachloroplatinate
10.3109/08958378.2015.1070219 · 2015 · External reference
Cross-reactivity between halogenated platinum salts in an immediate-type respiratory hypersensitivity model
10.1080/08958378.2018.1554015 · 2018 · External reference
Physiological responses to cisplatin using a mouse hypersensitivity model
10.1080/08958378.2020.1737762 · 2020 · External reference
Cisplatin-Induced Ototoxicity: Updates on Molecular Targets
10.1016/j.molmed.2019.08.002 · 2019 · External reference
PRDX1 activates autophagy via the PTEN-AKT signaling pathway to protect against cisplatin-induced spiral ganglion neuron damage
10.1080/15548627.2021.1905466 · 2021 · External reference
Cisplatin ototoxicity in rat cochlear organotypic cultures
10.1016/j.heares.2011.08.002 · 2011 · External reference
Mass changes and dissolution of platinum during electrical stimulation in artificial perilymph solution
10.1016/s0142-9612(00)00146-0 · 2000 · External reference
