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References from Survivin inhibition attenuates EGF-induced epithelial mesenchymal transformation of human RPE cells via the EGFR/MAPK pathway. Local targets link to admitted publications; unresolved targets remain external evidence.
Long noncoding RNA ERLR mediates epithelial-mesenchymal transition of retinal pigment epithelial cells and promotes experimental proliferative vitreoretinopathy
10.1038/s41418-021-00756-5 · 2021 · External reference
The retinal pigment epithelium in visual function
10.1152/physrev.00021.2004 · 2005 · External reference
Inhibition of PVR with a tyrosine kinase inhibitor, dasatinib, in the swine
10.1167/iovs.12-10418 · 2013 · External reference
Animal models of proliferative vitreoretinopathy and their use in pharmaceutical investigations
10.1159/000488492 · 2018 · External reference
EGFR signaling and autophagy dependence for growth, survival, and therapy resistance
10.4161/cc.27518 · 2014 · External reference
Cell signaling by receptor tyrosine kinases
10.1016/j.cell.2010.06.011 · 2010 · External reference
Glucosamine inhibits epidermal growth factor-induced proliferation and cell cycle progression in retinal pigment epithelial cells
2010 · External reference
Effects of curcumin on epidermal growth factor in proliferative vitreoretinopathy
10.1159/000491525 · 2018 · External reference
CMTM3 suppresses chordoma progress through EGFR/STAT3 regulated EMT and TP53 signaling pathway
10.1186/s12935-021-02159-5 · 2021 · External reference
Auranofin Inhibits Retinal Pigment Epithelium Cell Survival through Reactive Oxygen Species-Dependent Epidermal Growth Factor Receptor/ Mitogen-Activated Protein Kinase Signaling Pathway
10.1371/journal.pone.0166386 · 2016 · External reference
Oxidative stress affects retinal pigment epithelial cell survival through epidermal growth factor receptor/AKT signaling pathway
2017 · External reference
EGF Receptor Signaling Modulates YAP Activation and Promotes Experimental Proliferative Vitreoretinopathy
10.1167/iovs.63.8.24 · 2022 · External reference
Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype
10.1016/s0960-9822(00)00769-7 · 2000 · External reference
Survivin: a bifunctional inhibitor of apoptosis protein
10.1354/vp.41-6-599 · 2004 · External reference
Control of apoptosis and mitotic spindle checkpoint by survivin
10.1038/25141 · 1998 · External reference
Human RPE expression of cell survival factors
10.1167/iovs.04-1039 · 2005 · External reference
Green tea polyphenols attenuating ultraviolet B-induced damage to human retinal pigment epithelial cells in vitro
10.1167/iovs.10-5698 · 2010 · External reference
Knockdown of survivin results in inhibition of epithelial to mesenchymal transition in retinal pigment epithelial cells by attenuating the TGFβ pathway
10.1016/j.bbrc.2018.03.021 · 2018 · External reference
Epithelial-mesenchymal transition of circulating tumor cells in prostate cancer is promoted by survivin
10.1177/0300060519892395 · 2020 · External reference
The Role of Survivin and Transcription Factor FOXP1 in Scarring After Glaucoma Surgery
10.1167/tvst.11.2.19 · 2022 · External reference
YM155 Induces DNA Damage and Cell Death in Anaplastic Thyroid Cancer Cells by Inhibiting DNA Topoisomerase IIα at the ATP-Binding Site
10.1158/1535-7163.mct-21-0619 · 2022 · External reference
Ym155 Induces Oxidative Stress-Mediated DNA Damage and Cell Cycle Arrest, and Causes Programmed Cell Death in Anaplastic Thyroid Cancer Cells
10.3390/ijms22041961 · 2021 · External reference
YM155 inhibits retinal pigment epithelium cell survival through EGFR/MAPK signaling pathway
10.18240/ijo.2021.04.02 · 2021 · External reference
Notch signaling modulates proliferative vitreoretinopathy via regulating retinal pigment epithelial-to-mesenchymal transition
10.1007/s00418-016-1484-x · 2017 · External reference
Epithelial-mesenchymal transition and its transcription factors
10.1042/bsr20211754 · 2022 · External reference
Trichostatin A Inhibits Retinal Pigmented Epithelium Activation in an In vitro Model of Proliferative Vitreoretinopathy
10.1089/jop.2016.0038 · 2016 · External reference
Melatonin attenuates epidermal growth factor-induced cathepsin S expression in ARPE-19 cells: Implications for proliferative vitreoretinopathy
10.1111/jpi.12615 · 2020 · External reference
Neferine inhibits epidermal growth factor-induced proliferation and migration of retinal pigment epithelial cells through downregulating p38 MAPK and PI3K/AKT signalling
10.1080/15569527.2020.1730882 · 2020 · External reference
Cancer therapeutics using survivin BIRC5 as a target: what can we do after over two decades of study?
10.1186/s13046-019-1362-1 · 2019 · External reference
AKR1B10 promotes breast cancer cell proliferation and migration via the PI3K/AKT/NF-κB signaling pathway
10.1186/s13578-021-00677-3 · 2021 · External reference
Long Non-Coding RNA-CASC15 Promotes Cell Proliferation, Migration, and Invasion by Activating Wnt/β-Catenin Signaling Pathway in Melanoma
10.1159/000502803 · 2020 · External reference
Antiproliferative effect of bacterial cyclodipeptides in the HeLa line of human cervical cancer reveals multiple protein kinase targeting, including mTORC1/C2 complex inhibition in a TSC1/2-dependent manner
10.1007/s10495-020-01619-z · 2020 · External reference
EGF regulates survivin stability through the Raf-1/ERK pathway in insulin-secreting pancreatic β-cells
10.1186/1471-2199-11-66 · 2010 · External reference
Molecular Targeting of Epidermal Growth Factor Receptor (EGFR) and Vascular Endothelial Growth Factor Receptor (VEGFR)
10.3390/molecules26041076 · 2021 · External reference
The epidermal growth factor receptor axis and kidney fibrosis
10.1097/mnh.0000000000000696 · 2021 · External reference
Epidermal growth factor receptor in asthma: A promising therapeutic target?
10.1016/j.rmed.2023.107117 · 2023 · External reference
Epidermal growth factor, from gene organization to bedside
10.1016/j.semcdb.2014.01.011 · 2014 · External reference
Role of EGF receptor signaling on morphogenesis of eyelid and meibomian glands
10.1016/j.exer.2017.04.006 · 2017 · External reference
Epidermal growth factor receptor in cultured human retinal pigment epithelial cells
10.1159/000101926 · 2007 · External reference
EGFR signaling promotes β-cell proliferation and survivin expression during pregnancy
10.1371/journal.pone.0093651 · 2014 · External reference
Dihydromyricetin suppresses tumor growth via downregulation of the EGFR/Akt/survivin signaling pathway
10.1002/jbt.23328 · 2023 · External reference
YM155 induces EGFR suppression in pancreatic cancer cells
10.1371/journal.pone.0038625 · 2012 · External reference
Molecular mechanisms of epithelial-mesenchymal transition
10.1038/nrm3758 · 2014 · External reference
Signaling mechanisms of the epithelial-mesenchymal transition
10.1126/scisignal.2005189 · 2014 · External reference
New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer
10.1038/s41580-018-0080-4 · 2019 · External reference
A brief review of the histopathology of proliferative vitreoretinopathy (PVR)
10.1038/s41433-019-0724-4 · 2020 · External reference
Experimental Models to Study Epithelial-Mesenchymal Transition in Proliferative Vitreoretinopathy
10.3390/ijms24054509 · 2023 · External reference
