Research graph
References from Camellia sinensis methanolic leaves extract: Phytochemical analysis and anticancer activity against human liver cancer cells. Local targets link to admitted publications; unresolved targets remain external evidence.
Global Burden of Disease Liver Cancer Collaboration 2015 Mortality and Causes of Death Collaborators. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015
2016 · External reference
The burden of primary liver cancer and underlying etiologies from 1990 to 2015 at the global, regional, and national level: results from the global burden of disease study 2015
10.1001/jamaoncol.2017.3055 · 2017 · External reference
Global Cancer Statistics 2018: Globocan estimates of incidence and mortality worldwide for 36 cancers in 185 countries
10.3322/caac.21492 · 2018 · External reference
Hepatic oxidative DNA damage is associated with increased risk for hepatocellular carcinoma in chronic hepatitis C
10.1038/sj.bjc.6604204 · 2008 · External reference
Systemic chemotherapy with doxorubicin, cisplatin and capecitabine for metastatic hepatocellular carcinoma
2006 · External reference
Establishment of hepatocellular carcinoma multidrug resistant monoclone cell line HepG2/mdr1
10.1097/00029330-200704020-00017 · 2007 · External reference
Desirable cell death during anticancer chemotherapy
10.1111/j.1749-6632.2010.05763.x · 2010 · External reference
Frequency of citrus fruit intake is associated with the incidence of cardiovascular disease:The Jichi Medical School cohort study
10.2188/jea.je20100084 · 2011 · External reference
Intake of fruit, berries, and vegetables and risk of type 2 diabetes in Finnish men: The kuopio ischaemic heart disease risk factor study
10.3945/ajcn.113.069641 · 2014 · External reference
Unresolved reference
1982 · External reference
Cancer chemoprevention by resveratrol: in vitro and in vivo studies and the underlying mechanisms (review)
2003 · External reference
Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer
10.1016/j.lfs.2003.09.047 · 2004 · External reference
Beneficial Properties of Green Tea Catechins
10.3390/ijms21051744 · 2020 · External reference
Antioxidant and antiradical properties of green tea extract compounds
10.20964/2017.07.06 · 2017 · External reference
Epigallocatechin Gallate (EGCG) is the most effective cancer chemopreventive polyphenol in green tea
10.3390/nu4111679 · 2012 · External reference
Chemoprevention of breast cancer by dietary polyphenols
10.3390/molecules201219864 · 2015 · External reference
Effect of black and green tea polyphenols on c-jun phosphorylation and H2O2 production in transformed and non-transformed human bronchial cell lines: possible mechanisms of cell growth inhibition and apoptosis induction
10.1093/carcin/21.11.2035 · 2000 · External reference
Cell cycle dysregulation by green tea polyphenol epigallocatechin-3-gallate
10.1006/bbrc.2000.3297 · 2000 · External reference
Unresolved reference
2013 · External reference
Green tea: A promising anticancer agent for renal cell carcinoma
2010 · External reference
Determination of total phenol, favonoid, antioxidant activity of oil palm leaves extracts and their application in transparent soap
2018 · External reference
Estimation of total favonoid content in propolis by two complementary colometric methods
10.38212/2224-6614.2748 · 2020 · External reference
SCREENING OF IN-VITRO ANTIOXIDANT, BRINE SHRIMP LETHALITY BIOASSAY AND ANTIMICROBIAL ACTIVITIES OF EXTRACTS OF BRIDELIA RETUSA (L.) SPRENG. FRUIT
2015 · External reference
Analysis of Naturally Occurring Phenolic Compounds in Aromatic Plants by RP-HPLC Coupled to Diode Array Detector (DAD) and GC-MS after Silylation
10.3390/foods2010090 · 2013 · External reference
Stevia rebaudiana Methanolic Leaf Extract in Egypt: Phytochemical Analysis, Antioxidant, Antilipid Peroxidation, Antihemolytic, Antimetastatic, and Anticancer Properties
10.1155/2023/7161091 · 2023 · External reference
Saad. Nanocurcumin: preparation, characterization and cytotoxic effects towards human laryngeal cancer cells
10.1039/d0ra03719b · 2020 · External reference
The cross talk between type II diabetic microenvironment and the regenerative capacities of human adipose tissue-derived pericytes: a promising cell therapy
10.1186/s13287-024-03643-1 · 2024 · External reference
Synthesis and characterization of poly (3-hydroxybutyrate)/chitosan-graft poly (acrylic acid) conjugate hyaluronate for targeted delivery of methotrexate drug to colon cancer cells
10.1016/j.ijbiomac.2023.124396 · 2023 · External reference
Induction of mitochondria mediated apoptosis in human ovarian cancer cells by folic acid coated tin oxide nanoparticles
10.1371/journal.pone.0258115 · 2021 · External reference
Preparation of carrageenan/ chitosan-based (N,N,N-trimeth(yl chitosan chloride) silver nanocomposites as pH sensitive carrier for effective controlled curcumin delivery in cancer cells
10.1016/j.onano.2022.100050 · 2023 · External reference
Effective‐by‐method for the preparation of folic acid coated TiO2 nanoparticles with high targeting potential for apoptosis induction against bladder cancer cells (T24)
2023 · External reference
2012. Free radical scavenging and cytotoxic activity of five commercial standardized extracts (red wine, green tea, pine bark, polygonum and pomegranate)
2006 · External reference
Phase IIa chemoprevention trial of green tea polyphenols in high-risk individuals of liver cancer: modulation of urinary excretion of green tea polyphenols and 8-hydroxydeoxyguanosine
10.1093/carcin/bgi147 · 2006 · External reference
The antibacterial activity of acetic acid against bioflm-producing pathogens of relevance to burns patients
10.1371/journal.pone.0136190 · 2015 · External reference
Chemical Composition and In Vitro Antioxidant and Antimicrobial Activities of Marrubium vulgare L
10.1155/2021/7011493 · 2021 · External reference
Analysis of bioactive chemical components of two medicinal plants (Coriandrum sativum and Melia azedarach) leaves using gas chromatography-mass spectrometry (GC-MS)
10.5897/ajb2015.14956 · 2015 · External reference
Caffeic and 3-(3,4-dihydroxyphenyl)glyceric acid derivatives as antimicrobial agent: biological evaluation and molecular docking studies.
10.1080/1062936x.2022.2066173 · 2022 · External reference
Isolation, Characterization and Antibacterial activity of 4-(4-phenyl-1, 4-dihydronaphthalen-1-yl) Pentenoic Acid from the Stem Bark of Brachystegia eurycoma Harms.
2013 · External reference
Adiantumpedatum as anticancer, anti-oxidant and antiinflammatory agent
External reference
Erythritol is a sweet antioxidant
10.1016/j.nut.2009.05.004 · 2010 · External reference
Kenneth E. McMartin. Diglycolic acid inhibits succinate dehydrogenase activity in human proximal tubule cells leading to mitochondrial dysfunction and cell death
10.1016/j.toxlet.2013.06.231 · 2013 · External reference
HPLC based Phytochemicals Analysis of Phyllanthus emblica (Indian Gooseberry/Amla): A mini Review
10.18006/2024.12(2).266.273 · 2024 · External reference
GC–MS analysis of phytocomponents in the methanolic extract of Emblica officinalis Gaertn (Indian Gooseberry)
2014 · External reference
Evaluation of antifungal activity of Hexanoic acid (Hx) against Fusarium oxysporum f. sp. Lycopersici
2021 · External reference
Anticarcinogenic Effect and Carcinogenic Potential of the Dietary Phenolic Acid: o-Coumaric Acid
2013 · External reference
Review: Natural products from Genus Selaginella (Selaginellaceae)
External reference
Unresolved reference
2010 · External reference
The Biological activity of 3,4-O-Isopropylidene-3,3’4,5’-tetrahydroxystilbene
10.1248/cpb.33.2904 · 1985 · External reference
Synthesis, cytotoxicity and anti-inflammatory activity of rhamnose-containing ursolic and betulinic acid saponins
2019 · External reference
The antimicrobial activity of Croton membranaceus, a species used in formulations for measles in Ghana
2009 · External reference
Biological and Pharmacological Potential of Xylitol: A Molecular Insight of Unique Metabolism
10.3390/foods9111592 · 2020 · External reference
Antioxidant Properties of rare suga D-allose: Effects on mitochondrial reactive oxygen species production in Neuro2A cells
10.1016/j.jbiosc.2011.08.005 · 2011 · External reference
Itaconic acid exerts anti-infammatory and antibacterial efects via promoting pentose phosphate pathway to produce ROS
10.1038/s41598-021-97352-x · 2021 · External reference
Chemical Constituents of the Fruits of Morinda citrifolia (Noni) and Their Antioxidant Activity
10.1021/np0495985 · 2005 · External reference
Flavones: an important scaffold for medicinal chemistry
10.1016/j.ejmech.2014.07.013 · 2014 · External reference
Synthesis and biological activity of novel Pyrazolo[3,4-d]pyrimidin-4-one derivatives as potent antifungal agent Society of Chemical Industry
2021 · External reference
Synthesis and Antibacterial Activity of Alkylated Diamines and Amphiphilic Amides of Quinic Acid Derivatives.
10.1111/cbdd.12498 · 2015 · External reference
Synthesis and biological evaluation of novel coumarin derivatives with a 7-azomethine linkage
10.1016/j.bmcl.2003.11.060 · 2004 · External reference
Healthy properties of green and white teas: an update
10.1039/c7fo00611j · 2017 · External reference
Anticancer Effect of DL-Glyceraldehyde and 2-Deoxyglucose in Ehrlich Ascites Carcinoma Bearing Mice and Their Effect on Liver
10.1007/s12291-013-0343-y · 2014 · External reference
Synthesis and antitubercular activity of novel Schiff bases derived from D-mannitol
10.1016/j.carres.2009.08.006 · 2009 · External reference
Caffeine induces sustained apoptosis of human gastric cancer cells by activating the caspase-9/caspase-3 signalling pathway
10.3892/mmr.2017.6894 · 2017 · External reference
Overview of Caffeine Effects on Human Health and Emerging Delivery Strategies
10.3390/ph16081067 · 2023 · External reference
Tea polyphenols- their antioxidant properties and biological activity–a review.
2005 · External reference
Bioactive ellagitannins from Cunonia macrophylla, an endemic Cunoniaceae from New Caledonia
10.1016/j.phytochem.2004.11.016 · 2005 · External reference
Phytotoxic and antimicrobial constituents of Argyreia speciosa and Oenothera biennis
10.1016/s0378-8741(99)00017-3 · 1999 · External reference
The in vitro cytotoxic and apoptotic activity of Triphala–an Indian herbal drug
10.1016/j.jep.2004.09.050 · 2005 · External reference
Mohammed AL-Shwany, Synthesis and Antibacterial activities of some Arabinofuranose-Schiff bases Derivatives
2016 · External reference
c d Boopathi subramaniyam, Rajaram Virumandy. Antioxidant and Antimicrobial properties of Glycine Max-A review
2011 · External reference
Synthesis, Metal Ions Coordination, Antimicrobial Activity of Some L-Tartaric Acid Derivatives
2012 · External reference
Antiviral activity of palmitic acid via autophagic flux inhibition in zebrafish (Danio rerio)
10.1016/j.fsi.2019.10.055 · 2019 · External reference
Synthesis of triazole derivatives of Levoglucosenone as promising anticancer agents: efective exploration of the chemical space through retro-aza-Michael//aza-Michael isomerizations
10.1021/acs.joc.7b03141 · 2018 · External reference
Novel chemical and biological insights of inositol derivatives in mediterranean plants
10.3390/molecules27051525 · 2022 · External reference
Isabelle Gosselin b, Cécile Machut c, Patrick Martin. Synthesis, surface tension properties and antibacterial activities of amphiphilic D-galactopyranose derivatives
2013 · External reference
Evaluation of thymol-β-d-glucopyranoside as a potential prebiotic intervention to reduce carriage of zoonotic pathogens in weaned and feeder pigs
10.3390/microorganisms9040860 · 2021 · External reference
Investigation of antioxidant and anticancer activities of unsaturated oligo-galacturonic acids produced by pectinase of Streptomyces hydrogenans YAM1
10.1038/s41598-021-87804-9 · 2021 · External reference
Enzymatic Synthesis of Maltitol and Its Inhibitory Effect on the Growth of Streptococcus mutans DMST 18777
10.3390/biom12020167 · 2022 · External reference
Impact of Molybdenum Compounds as Anticancer Agents
2019 · External reference
Synthesis and Characterization of Some New Glycosides Derived from The Sugar D-ribose of Expected Biological Activity
2016 · External reference
Kombucha tea prevents obese mice from developing hepatic steatosis and liver damage
10.1007/s10068-016-0142-3 · 2016 · External reference
Unresolved reference
2016 · External reference
The beneficial biological properties of salicylic acid
10.1515/afmnai-2015-0026 · 2015 · External reference
Antibacterial activity of glycerol, lactose, maltose, mannitol, raffinose and xylose
2014 · External reference
Extraction Methods, Chemical Characterization, and In Vitro Biological Activities of Plinia cauliflora (Mart.) Kausel Peels
10.3390/ph16081173 · 2023 · External reference
Effects of lactulose on renal function and gut microbiota in adenineinduced chronic kidney disease rats
10.1007/s10157-019-01727-4 · 2019 · External reference
Synthesis of New D-xylose Derivatives and Study Their Antimicrobial Effect
2014 · External reference
Evaluation of ´thymol-β-d-glucopyranoside as a potential prebiotic intervention to reduce carriage of zoonotic pathogens in weaned and feeder pigs
10.3390/microorganisms9040860 · 2021 · External reference
Mohammed AL-Shwany, Synthesis and Antibacterial activities of some Arabinofuranose-Schiff bases Derivatives
2016 · External reference
Anti-Dengue, Cytotoxicity, Antifungal, and In Silico Study of the Newly Synthesized 3-O-Phospo-alpha-D-Glucopyranuronic Acid Compound
2018 · External reference
Hydroxybenzoic acid isomers and the cardiovascular system
10.1186/1475-2891-13-63 · 2014 · External reference
Antioxidant & anticancer activities of isatin (1H-indole-2,3-dione), isolated from the flowers of Couroupita guianensis Aubl
2012 · External reference
Chemical and pharmacological aspects of caffeic acid and its activity in hepatocarcinoma
2019 · External reference
Cell growth inhibitory dihydrophenanthrene and phenanthrene constituents of the african tree Combretum cafrum
10.1139/v88-071 · 1988 · External reference
Yasman. Antibacterial and antioxidant activity of sea cucumber extracts collected from Lampung waters
10.1016/j.kjs.2023.03.012 · 2023 · External reference
Antibacterial activity of glycerol, lactose, maltose, mannitol, rafnose and xylose
2014 · External reference
Inhibitory effect of d-arabinose on oral bacteria biofilm formation on titanium discs
10.1016/j.anaerobe.2022.102533 · 2022 · External reference
Screening of fatty acids, saccharides, and phytochemicals in Jatropha curcas seed kernel as their trimethylsilyl derivatives using gas chromatography/mass spectrometry
10.1016/j.jchromb.2018.10.009 · 2018 · External reference
Protocatechuic acid protects hepatocytes against hydrogen peroxide-induced oxidative stress
10.1016/j.crfs.2022.01.006 · 2022 · External reference
Phytochemical analysis and comprehensive evaluation of antimicrobial and antioxidant properties of 61 medicinal plant species
10.1016/j.arabjc.2015.01.013 · 2018 · External reference
Medicinal plants and cancer chemoprevention
10.2174/138920008785821657 · 2008 · External reference
Phenolics as potential antioxidant therapeutic agents: mechanism and actions
10.1016/j.mrfmmm.2005.03.023 · 2005 · External reference
Bioactive compounds, antioxidant and antimicrobial activities of Arum maculatum leaves extracts as afected by various solvents and extraction methods
10.1002/fsn3.815 · 2019 · External reference
Evaluation of antioxidant activity of leaf extract of sea buckthorn (Hippophae rhamnoides L.) on chromium (VI) induced oxidative stress in albino rats
10.1016/s0378-8741(03)00154-5 · 2003 · External reference
Radioprotective efects of antioxidative plant favonoidsin mice
10.1016/0027-5107(95)00116-6 · 1996 · External reference
Phenol content and antioxidant activity of green, yellow and black tea leaves
10.1186/s40538-014-0028-7 · 2015 · External reference
Overexpression of SIRT1 promotes metastasis through epithelial-mesenchymal transition in hepatocellular carcinoma
2014 · External reference
Formulation, Characterization and Biological Activity Screening of Sodium Alginate-Gum Arabic Nanoparticles Loaded with Curcumin
2020 · External reference
Development and optimization of curcumin analog nano-bilosomes using 21.31 full factorial design for anti-tumor profiles improvement in human hepatocellular carcinoma: in-vitro evaluation, in-vivo safety assay
10.1080/10717544.2022.2044938 · 2022 · External reference
Curcumin Activates ROS Signaling to Promote Pyroptosis in Hepatocellular Carcinoma HepG2
10.21873/invivo.12253 · 2021 · External reference
EGCG inhibits growth, invasion, angiogenesis and metastasis of pancreatic cancer
10.2741/2691 · 2008 · External reference
-Epigallocatechin gallate and polyphenon E inhibit growth and activation of the epidermal growth factor receptor and human epidermal growth factor receptor-2 signaling pathways in human colon cancer cells
10.1158/1078-0432.ccr-04-2014 · 2005 · External reference
Nanocurcumin and curcumin prevent N, N’-methylenebisacrylamide-induced liver damage and promotion of hepatic cancer cell growth
10.1038/s41598-022-12406-y · 2022 · External reference
Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis
10.1074/jbc.273.16.9357 · 1998 · External reference
Mitochondrial and Nuclear DNA Damage Induced by Curcumin in Human Hepatoma G2 Cells
10.1093/toxsci/kfj153 · 2006 · External reference
Apoptosis and necrosis of human breast cancer cells by an aqueous extract of garden cress (Lepidium sativum) seeds
10.1016/j.sjbs.2012.12.002 · 2013 · External reference
The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer,”
10.1046/j.1365-2184.2003.00266.x · 2003 · External reference
Curcumin induces mitochondrial apoptosis in human hepatoma cells through BCLAF1-mediated modulation of PI3K/AKT/GSK-3β signaling
10.1016/j.lfs.2022.120804 · 2022 · External reference
Effects of epigallocatechin-3-gallate on growth, epidermal growth factor receptor signaling pathways, gene expression, and chemosensitivity in human head and neck squamous cell carcinoma cell lines
2001 · External reference
-Epigallocatechin gallate and polyphenon E inhibit growth and activation of the epidermal growth factor receptor and human epidermal growth factor receptor-2 signaling pathways in human colon cancer cells
10.1158/1078-0432.ccr-04-2014 · 2005 · External reference
Resveratrol induces cell cycle arrest and apoptosis with docetaxel in prostate cancer cells via a p53/ p21 and p27 pathway
10.18632/oncotarget.15303 · 2017 · External reference
Mitochondrial dysfunction route as a possible biomarker and therapy target for human cancer
10.1016/j.bj.2024.100714 · 2024 · External reference
Reactive oxygen species: a key constituent in cancer survival
External reference
Downregulation of reactive oxygen species in apoptosis
10.15430/jcp.2016.21.1.13 · 2016 · External reference
Anticancer Activity of Smallanthus sonchifolius Methanol Extract against Human Hepatocellular Carcinoma Cells
10.3390/molecules24173054 · 2019 · External reference
Curcumin Activates ROS Signaling to Promote Pyroptosis in Hepatocellular Carcinoma HepG2
10.21873/invivo.12253 · 2021 · External reference
Bcl-2-regulated apoptosis: mechanism and therapeutic potential
10.1016/j.coi.2007.05.004 · 2007 · External reference
Caspase-mediated Bak activation and cytochrome c release during intrinsic apoptotic cell death in Jurkat cells
10.1074/jbc.m807656200 · 2008 · External reference
Caspase-3 promotes genetic instability and carcinogenesis
10.1016/j.molcel.2015.03.003 · 2015 · External reference
Curcumin induces apoptosis in human hepatocellular carcinoma cells by decreasing the expression of STAT3/VEGF/HIF-1α signaling
10.1515/biol-2022-0618 · 2023 · External reference
