Research graph
References from Gentiopicroside-Induced gastric cancer necroptosis via the HIF-1 signaling pathway: A study involving molecular docking and experimental validation. Local targets link to admitted publications; unresolved targets remain external evidence.
Initiation and execution mechanisms of necroptosis: an overview
10.1038/cdd.2017.65 · 2017 · External reference
Biomarkers for the detection of necroptosis
10.1007/s00018-016-2192-3 · 2016 · External reference
Necroptosis Related Genes Predict Prognosis and Therapeutic Potential in Gastric Cancer
10.3390/biom13010101 · 2023 · External reference
A novel necroptosis-related gene index for predicting prognosis and a cold tumor immune microenvironment in stomach adenocarcinoma
10.3389/fimmu.2022.968165 · 2022 · External reference
Development and validation of a necroptosis-related gene prognostic score to predict prognosis and efficiency of immunotherapy in gastric cancer
10.3389/fimmu.2022.977338 · 2022 · External reference
A novel prognostic and therapeutic target biomarker based on necroptosis-related gene signature and immune microenvironment infiltration in gastric cancer
10.3389/fgene.2022.953997 · 2022 · External reference
Benzophenanthridine Alkaloid Chelerythrine Elicits Necroptosis of Gastric Cancer Cells via Selective Conjugation at the Redox Hyperreactive C-Terminal Sec498 Residue of Cytosolic Selenoprotein Thioredoxin Reductase.
10.3390/molecules28196842 · 2023 · External reference
Gambogic Acid Inhibits Gastric Cancer Cell Proliferation through Necroptosis
10.1155/2023/7532367 · 2023 · External reference
Therapeutic effects of gentiopicroside on adjuvant-induced arthritis by inhibiting inflammation and oxidative stress in rats
10.1016/j.intimp.2019.105840 · 2019 · External reference
Anti-apoptotic activity of gentiopicroside in D-galactosamine/lipopolysaccharide-induced murine fulminant hepatic failure
10.1016/j.cbi.2010.06.004 · 2010 · External reference
Gentiopicroside exerts convincing antitumor effects in human ovarian carcinoma cells (SKOV3) by inducing cell cycle arrest, mitochondrial mediated apoptosis and inhibition of cell migration.
2019 · External reference
Protective effect of gentiopicroside from Gentiana macrophylla Pall.
10.1002/ptr.5965 · 2018 · External reference
Research on the Potential Mechanism of Gentiopicroside Against Gastric Cancer Based on Network Pharmacology.
10.2147/dddt.s270757 · 2020 · External reference
Pyroptosis versus necroptosis: similarities, differences, and crosstalk
10.1038/s41418-018-0212-6 · 2019 · External reference
HIF-1α pathway: role, regulation and intervention for cancer therapy
10.1016/j.apsb.2015.05.007 · 2015 · External reference
Hypoxia-induced HIF-1α/lncRNA-PMAN inhibits ferroptosis by promoting the cytoplasmic translocation of ELAVL1 in peritoneal dissemination from gastric cancer
10.1016/j.redox.2022.102312 · 2022 · External reference
HIF-1α (Hypoxia-Inducible Factor-1α) Promotes Macrophage Necroptosis by Regulating miR-210 and miR-383
10.1161/atvbaha.119.313290 · 2020 · External reference
Combining machine learning systems and multiple docking simulation packages to improve docking prediction reliability for network pharmacology
10.1371/journal.pone.0083922 · 2013 · External reference
AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
10.1002/jcc.21334 · 2010 · External reference
Shortcuts for faster image creation in PyMOL
10.1002/pro.3781 · 2020 · External reference
Contamination of SVG p12 cells with BK polyomavirus occurred after deposit in the American Type Culture Collection
10.1128/jvi.01600-14 · 2014 · External reference
Necrostatin-1 Prevents Ferroptosis in a RIPK1- and IDO-Independent Manner in Hepatocellular Carcinoma.
10.3390/antiox10091347 · 2021 · External reference
Melatonin alleviates lipopolysaccharide-induced myocardial injury by inhibiting inflammation and pyroptosis in cardiomyocytes
10.21037/atm-20-8196 · 2021 · External reference
GDC-0326 Enhances the Effects of 5-Fu in Colorectal Cancer Cells by Inducing Necroptotic Death.
10.2147/ott.s302334 · 2021 · External reference
Shikonin induces necroptosis by reactive oxygen species activation in nasopharyngeal carcinoma cell line CNE-2Z
10.1007/s10863-017-9714-z · 2017 · External reference
Interferon-gamma regulates inflammatory cell death by targeting necroptosis in experimental autoimmune arthritis
10.1038/s41598-017-09767-0 · 2017 · External reference
Shear stress associated with cardiopulmonary bypass induces expression of inflammatory cytokines and necroptosis in monocytes.
10.1172/jci.insight.141341 · 2021 · External reference
Study on Inhibitory Effect of MaiMenDong Decoction and WeiJing Decoction Combination with Cisplatin on NCI-A549
2017 · External reference
Intratumoral injection of cisplatin in various concentrations of ethanol for cisplatin-resistant lung tumors
10.3892/mco.2014.275 · 2014 · External reference
Therapeutic Effect of pHLIP-mediated CEACAM6 Gene Silencing
2019 · External reference
Herbal Formula Modified Bu-Shen-Huo-Xue Decoction Attenuates Intervertebral Disc Degeneration via Regulating Inflammation and Oxidative Stress
2022 · External reference
Necroptosis in the Pathophysiology of Disease
10.1016/j.ajpath.2019.10.012 · 2020 · External reference
Necroptosis: STAT3 kills?
2012 · External reference
HMGB1/TLR4 signaling pathway enhances abdominal aortic aneurysm progression in mice by upregulating necroptosis
10.1007/s00011-023-01694-3 · 2023 · External reference
Role of RIPK3‑CaMKII‑mPTP signaling pathway‑mediated necroptosis in cardiovascular diseases (Review).
10.3892/ijmm.2023.5301 · 2023 · External reference
Exosomes derived from schwann cells alleviate mitochondrial dysfunction and necroptosis after spinal cord injury via AMPK signaling pathway-mediated mitophagy
10.1016/j.freeradbiomed.2023.08.026 · 2023 · External reference
Regulation of JNK signaling pathway and RIPK3/AIF in necroptosis-mediated global cerebral ischemia/reperfusion injury in rats
10.1016/j.expneurol.2020.113374 · 2020 · External reference
Hypoxia inducible factor-1α is an important regulator of macrophage biology
10.1016/j.heliyon.2023.e17167 · 2023 · External reference
Resistance to hypoxia-induced necroptosis is conferred by glycolytic pyruvate scavenging of mitochondrial superoxide in colorectal cancer cells
10.1038/cddis.2013.149 · 2013 · External reference
HIF-1α (Hypoxia-Inducible Factor-1α) Promotes Macrophage Necroptosis by Regulating miR-210 and miR-383.
10.1161/atvbaha.119.313290 · 2020 · External reference
Hypoxia-inducible factor-1 alpha is involved in RIP-induced necroptosis caused by in vitro and in vivo ischemic brain injury
10.1038/s41598-017-06088-0 · 2017 · External reference
A network pharmacology-based investigation of brugine reveals its multi-target molecular mechanism against Breast Cancer
10.1007/s12032-023-02067-w · 2023 · External reference
Comparison of the anti-inflammatory and analgesic effects of Gentiana macrophylla Pall. and Gentiana straminea Maxim., and identification of their active constituents
10.1016/j.jep.2012.10.004 · 2012 · External reference
Concurrent Extraction and Purification of Gentiopicroside from Gentiana scabra Bunge Using Microwave-Assisted Ethanol-Salt Aqueous Two-Phase Systems
10.1093/chromsci/bmz101 · 2019 · External reference
Analysis of chemical constituents of Tibetan medicine Gentiana robusta King ex Hook.f. radix by UPLC-ESI-Q-TOF-MS/MS.
2023 · External reference
Gentiopicroside-An Insight into Its Pharmacological Significance and Future Perspectives.
10.3390/cells13010070 · 2023 · External reference
Gentiopicroside Inhibits Cell Growth and Migration on Cervical Cancer via the Reciprocal MAPK/Akt Signaling Pathways
10.1080/01635581.2020.1801777 · 2021 · External reference
Gentiopicroside inhibits the progression of gastric cancer through modulating EGFR/PI3K/AKT signaling pathway
10.1186/s40001-024-01637-6 · 2024 · External reference
Influence of different hypoxia models on metastatic potential of SGC-7901 gastric cancer cells
10.1007/s13277-014-1928-7 · 2014 · External reference
