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References from Cross-species conserved miRNA as biomarker of radiation injury over a wide dose range using nonhuman primate model. Local targets link to admitted publications; unresolved targets remain external evidence.
Medical and policy considerations for nuclear and radiation accidents, incidents and terrorism
10.1097/moh.0000000000000380 · 2017 · External reference
Nuclear and Radiological Emergencies: Biological Effects, Countermeasures and Biodosimetry
2022 · External reference
Review of retrospective dosimetry techniques for external ionising radiation exposures
10.1093/rpd/ncq499 · 2011 · External reference
Uncertainty on radiation doses estimated by biological and retrospective physical methods
10.1093/rpd/ncx125 · 2018 · External reference
A review of radiation-induced alterations of multi-omic profiles, radiation injury biomarkers, and countermeasures
10.1667/rade-21-00187.1 · 2023 · External reference
Use of biomarkers for assessing radiation injury and efficacy of countermeasures
10.1586/14737159.2016.1121102 · 2016 · External reference
Lymphocyte depletion rate as a biomarker of radiation dose to circulating lymphocytes during fractionated partial-body radiation therapy
10.1016/j.adro.2022.100959 · 2022 · External reference
Lessons from past radiation accidents: Critical review of methods addressed to individual dose assessment of potentially exposed people and integration with medical assessment
10.1016/j.envint.2020.106175 · 2021 · External reference
Potential application of gamma-H2AX as a biodosimetry tool for radiation triage
10.1016/j.mrrev.2020.108350 · 2021 · External reference
Biomarkers as drug development tools: discovery, validation, qualification and use
10.1038/s41584-018-0005-9 · 2018 · External reference
Biomarkers for acute radiation syndrome: Challenges for developing radiation countermeasures following animal rule
10.1080/14737159.2018.1533404 · 2018 · External reference
Metabolomics-based predictive biomarkers of radiation injury and countermeasure efficacy: Current status and future perspectives
10.1080/14737159.2021.1933448 · 2021 · External reference
Metabolomic applications in radiation biodosimetry: exploring radiation effects through small molecules
10.1080/09553002.2016.1269218 · 2017 · External reference
A systematic review of metabolomic and lipidomic candidates for biomarkers in radiation injury
10.3390/metabo10060259 · 2020 · External reference
Unresolved reference
External reference
Identification of novel biomarkers for acute radiation injury using multiomics approach and nonhuman primate model
10.1016/j.ijrobp.2022.05.046 · 2022 · External reference
The microcosmos of cancer
10.1038/nature10888 · 2012 · External reference
Mechanisms of miRNA-mediated gene regulation from common downregulation to mRNA-specific upregulation
10.1155/2014/970607 · 2014 · External reference
The roles of microRNAs in epigenetic regulation
10.1016/j.cbpa.2019.01.024 · 2019 · External reference
Epigenetics in Health and Disease
10.1007/978-981-15-3449-2_1 · 2020 · External reference
MicroRNAs: Biomarkers, Diagnostics, and Therapeutics
10.1007/978-1-4939-7046-9_4 · 2017 · External reference
Circulating microRNA biomarker studies: pitfalls and potential solutions
10.1373/clinchem.2014.221341 · 2015 · External reference
Medical management of the acute radiation syndrome: recommendations of the Strategic National Stockpile Radiation Working Group
10.7326/0003-4819-140-12-200406150-00015 · 2004 · External reference
Serum microRNAs–potent biomarkers for radiation biodosimetry
10.18632/oncotarget.24381 · 2018 · External reference
Ionizing radiation-induced altered microRNA expression as biomarkers for assessing acute radiation injury
10.1080/14737159.2017.1366316 · 2017 · External reference
Changes in miRNA in the lung and whole blood after whole thorax irradiation in rats
10.1038/srep44132 · 2017 · External reference
Serum microRNAs are early indicators of survival after radiation-induced hematopoietic injury
10.1126/scitranslmed.aaa6593 · 2015 · External reference
Evolutionarily conserved serum microRNAs predict radiation-induced fatality in nonhuman primates
10.1126/scitranslmed.aal2408 · 2017 · External reference
microRNA and metabolite signatures linked to early consequences of lethal radiation
10.1038/s41598-020-62255-w · 2020 · External reference
Circulating microRNAs as biomarkers of radiation exposure: a systematic review and meta-analysis
10.1016/j.ijrobp.2019.10.028 · 2020 · External reference
Protein biomarkers for radiation injury and testing of medical countermeasure efficacy: promises, pitfalls, and future directions
10.1080/14789450.2023.2263652 · 2023 · External reference
Machine learning & molecular radiation tumor biomarkers
10.1016/j.semradonc.2023.03.002 · 2023 · External reference
Serum miRNA-based signature indicates radiation exposure and dose in humans: A multicenter diagnostic biomarker study
10.1016/j.radonc.2023.109731 · 2023 · External reference
Serum microRNAs as xerostomia biomarkers in patients with oropharyngeal cancer undergoing radiation therapy
10.1016/j.ijrobp.2021.07.008 · 2021 · External reference
Serum microRNA signature predicts response to high-dose radiation therapy in locally advanced non-small cell lung cancer
10.1016/j.ijrobp.2017.08.039 · 2018 · External reference
Serum microRNAs as early indicators for estimation of exposure degree in response to ionizing irradiation
10.1667/rr14702.1 · 2017 · External reference
Limitations of animal studies for predicting toxicity in clinical trials: Is it time to rethink our current approach?
10.1016/j.jacbts.2019.10.008 · 2019 · External reference
Early to sustained impacts of lethal radiation on circulating miRNAs in a minipig model
10.1038/s41598-023-45250-9 · 2023 · External reference
Radioprotective efficacy of gamma-tocotrienol in nonhuman primates
10.1667/rr14127.1 · 2016 · External reference
Determination of lethality curve for cobalt-60 gamma-radiation source in rhesus macaques using subject-based supportive care
10.1667/rade-22-00101.1 · 2022 · External reference
Transcriptome of rhesus macaque (Macaca mulatta) exposed to total-body irradiation
10.1038/s41598-021-85669-6 · 2021 · External reference
Unresolved reference
2011 · External reference
Effects of gamma-tocotrienol on intestinal injury in a GI-specific acute radiation syndrome model in nonhuman primate.
10.3390/ijms23094643 · 2022 · External reference
Accuracy considerations in EPR dosimetry
10.1016/s0969-8043(00)00052-x · 2000 · External reference
Unresolved reference
2013 · External reference
Lung transcriptome of nonhuman primates exposed to total- and partial-body irradiation
10.1016/j.omtn.2022.08.006 · 2022 · External reference
Unresolved reference
External reference
Effects of gamma-tocotrienol on partial-body irradiation-induced intestinal injury in a nonhuman primate model
10.3390/antiox11101895 · 2022 · External reference
Gamma-tocotrienol modulates total-body irradiation-induced hematopoietic injury in a nonhuman primate model
10.3390/ijms232416170 · 2022 · External reference
Contributions of polyunsaturated fatty acids (PUFA) on cerebral neurobiology: an integrated omics approach with epigenomic focus
10.1016/j.jnutbio.2016.12.006 · 2017 · External reference
Calculating sample size estimates for RNA sequencing data
10.1089/cmb.2012.0283 · 2013 · External reference
Multiple sequence alignment using ClustalW and ClustalX
2003 · External reference
Biomarker discovery process at binomial decision point (2BDP): Analytical pipeline to construct biomarker panel
10.1016/j.csbj.2023.09.025 · 2023 · External reference
A mammalian microRNA expression atlas based on small RNA library sequencing
10.1016/j.cell.2007.04.040 · 2007 · External reference
Non-human primates as a model for human development
10.1016/j.stemcr.2021.03.021 · 2021 · External reference
MicroRNA-183-5p: A new potential marker for prostate cancer
10.1007/s12291-017-0731-9 · 2019 · External reference
Upregulation of miR-183-5p predicts worse survival in patients with renal cell cancer after surgery
10.3233/cbm-182047 · 2019 · External reference
miR-183-5p acts as a potential prognostic biomarker in gastric cancer and regulates cell functions by modulating EEF2
10.1016/j.prp.2019.152636 · 2019 · External reference
miR-183-5p enhances the radioresistance of colorectal cancer by directly targeting ATG5
10.1007/s12038-019-9918-y · 2019 · External reference
MiR-183-5p alleviates chronic constriction injury-induced neuropathic pain through inhibition of TREK-1
10.1007/s11064-018-2529-4 · 2018 · External reference
Non-coding RNAs in neuropathic pain
10.1042/ns20190099 · 2020 · External reference
MiR-30c-5p suppresses migration, invasion and epithelial to mesenchymal transition of gastric cancer via targeting MTA1
10.1016/j.biopha.2017.06.084 · 2017 · External reference
miR-424-5p promotes proliferation, migration and invasion of laryngeal squamous cell carcinoma
10.2147/ott.s224325 · 2019 · External reference
Identification of hub genes associated with progression and prognosis in patients with bladder cancer
10.3389/fgene.2019.00408 · 2019 · External reference
Co-expression network analysis identifies four hub genes associated with prognosis in soft tissue sarcoma
10.3389/fgene.2019.00037 · 2019 · External reference
Identifying serum miRNA biomarkers for radiation exposure in hematopoietic humanized NSG-SGM3 mice
10.1016/j.bbrc.2022.02.010 · 2022 · External reference
Clinical significance of let-7a-5p and miR-21-5p in patients with breast cancer
2019 · External reference
Molecular Mechanisms of Radiation-Induced Cancer Cell Death: A Primer
10.3389/fcell.2020.00041 · 2020 · External reference
Biological effects of radiation on cancer cells
2018 · External reference
MiR-23a-3p acts as an oncogene and potential prognostic biomarker by targeting PNRC2 in RCC
10.1016/j.biopha.2018.11.065 · 2019 · External reference
A review on the role of mir-16-5p in the carcinogenesis
10.1186/s12935-022-02754-0 · 2022 · External reference
Understanding the common mechanisms of heart and skeletal muscle wasting in cancer cachexia
10.1038/s41389-020-00288-6 · 2021 · External reference
Cachexia in cancer: what is in the definition?
10.1136/bmjgast-2016-000097 · 2016 · External reference
MicroRNAs: Novel players in the diagnosis and treatment of cancer cachexia (Review)
10.3892/etm.2022.11373 · 2022 · External reference
Biomarker Panels in Critical Care
10.1016/j.ccc.2019.08.007 · 2020 · External reference
The Future of Biomarkers
10.1016/j.ccc.2019.08.014 · 2020 · External reference
Emergence of pathway-level composite biomarkers from converging gene set signals of heterogeneous transcriptomic responses
2018 · External reference
MammaPrint70-gene signature: another milestone in personalized medical care for breast cancer patients
10.1586/erm.09.32 · 2009 · External reference
Srkalovic GJAma. Prospective validation of a genomic assay in breast cancer: The 70-gene MammaPrint assay and the MINDACT trial
10.5644/ama2006-124.239 · 2019 · External reference
LncRNA-LINC00152 down-regulated by miR-376c-3p restricts viability and promotes apoptosis of colorectal cancer cells
2016 · External reference
miR-342-3p suppresses proliferation, migration and invasion by targeting FOXM1 in human cervical cancer
10.1016/j.febslet.2014.07.020 · 2014 · External reference
miR-363-3p inhibits tumor growth by targeting PCNA in lung adenocarcinoma
10.18632/oncotarget.15448 · 2017 · External reference
MiR-143-3p suppresses the progression of ovarian cancer
2018 · External reference
MicroRNA-301a-3p promotes pancreatic cancer progression via negative regulation of SMAD4
10.18632/oncotarget.4124 · 2015 · External reference
miR-92b-3p acts as a tumor suppressor by targeting Gabra3 in pancreatic cancer
10.1186/s12943-017-0723-7 · 2017 · External reference
Colorectal cancer-derived exosomal miR-106b-3p promotes metastasis by down-regulating DLC-1 expression
10.1042/cs20191087 · 2020 · External reference
MiR-28-3p as a potential plasma marker in diagnosis of pulmonary embolism
10.1016/j.thromres.2015.12.006 · 2016 · External reference
miR-342-3p targets RAP2B to suppress proliferation and invasion of non-small cell lung cancer cells
10.1007/s13277-015-3154-3 · 2015 · External reference