Research graph
References from Single-cell sequencing reveals transcriptional dynamics regulated by ERα in mouse ovaries. Local targets link to admitted publications; unresolved targets remain external evidence.
Estrogen synthesis and signaling pathways during aging: from periphery to brain
10.1016/j.molmed.2012.12.007 · 2013 · External reference
Nuclear hormone receptors and gene expression
10.1152/physrev.2001.81.3.1269 · 2001 · External reference
Estrogen dependent signaling in reproductive tissues—a role for estrogen receptors and estrogen related receptors
10.1016/j.mce.2011.09.026 · 2012 · External reference
What’s new in estrogen receptor action in the female reproductive tract
10.1530/jme-15-0254 · 2016 · External reference
Overview of nomenclature of nuclear receptors
10.1124/pr.58.4.2 · 2006 · External reference
Nuclear receptor ligand-binding domains: three-dimensional structures, molecular interactions and pharmacological implications
10.1016/s0165-6147(00)01548-0 · 2000 · External reference
Estrogen receptors: selective ligands, partners, and distinctive pharmacology
2000 · External reference
Characterization of the hypothalamic-pituitary-gonadal axis in estrogen receptor (ER) Null mice reveals hypergonadism and endocrine sex reversal in females lacking ERalpha but not ERbeta
10.1210/me.2002-0398 · 2003 · External reference
Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene
10.1073/pnas.95.12.6965 · 1998 · External reference
Generation and reproductive phenotypes of mice lacking estrogen receptor beta
10.1073/pnas.95.26.15677 · 1998 · External reference
Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes
10.1242/dev.127.19.4277 · 2000 · External reference
Postnatal sex reversal of the ovaries in mice lacking estrogen receptors alpha and beta
10.1126/science.286.5448.2328 · 1999 · External reference
Single-cell RNA sequencing reveals the landscape of early female germ cell development
10.1096/fj.202001034rr · 2020 · External reference
Single-cell analysis of human ovarian cortex identifies distinct cell populations but no oogonial stem cells
10.1038/s41467-020-14936-3 · 2020 · External reference
Single-Cell Transcriptomic Atlas of Primate Ovarian Aging
10.1016/j.cell.2020.01.009 · 2020 · External reference
Single-cell reconstruction of follicular remodeling in the human adult ovary
10.1038/s41467-019-11036-9 · 2019 · External reference
Single-cell sequencing of neonatal uterus reveals an Misr2+ endometrial progenitor indispensable for fertility
10.7554/elife.46349 · 2019 · External reference
The absence of ER-β results in altered gene expression in ovarian granulosa cells isolated from in vivo preovulatory follicles
10.1210/en.2012-2256 · 2013 · External reference
A single-cell atlas of the cycling murine ovary
10.7554/elife.77239 · 2022 · External reference
Functional Oocytes Derived from Granulosa Cells
10.1016/j.celrep.2019.11.080 · 2019 · External reference
Cholesterol ester droplets and steroidogenesis
10.1016/j.mce.2012.10.012 · 2013 · External reference
The ovarian estrogen synthesis function was impaired in Y123F mouse and partly restored by exogenous FSH supplement
10.1186/s12958-018-0365-7 · 2018 · External reference
Latent TGF-β binding protein-1 deficiency decreases female fertility
10.1016/j.bbrc.2016.12.046 · 2017 · External reference
Regulation of progesterone levels during pregnancy and parturition by signal transducer and activator of transcription 5 and 20alpha-hydroxysteroid dehydrogenase
10.1210/me.2004-0302 · 2005 · External reference
Genomewide discovery and classification of candidate ovarian fertility genes in the mouse
10.1534/genetics.107.074823 · 2007 · External reference
17β-estradiol upregulates GREB1 and accelerates ovarian tumor progression in vivo
10.1002/ijc.28741 · 2014 · External reference
PDZK1 and GREB1 are estrogen-regulated genes expressed in hormone-responsive breast cancer
2000 · External reference
GREB 1 is a critical regulator of hormone dependent breast cancer growth
10.1007/s10549-005-1483-4 · 2005 · External reference
GREB1 is an estrogen receptor-regulated tumour promoter that is frequently expressed in ovarian cancer
10.1038/s41388-018-0377-y · 2018 · External reference
Estradiol promotes cell survival and induces Greb1 expression in granulosa cell tumors of the ovary through an ERα-dependent mechanism
10.1002/path.5843 · 2022 · External reference
Zearalenone exposure impairs ovarian primordial follicle formation via down-regulation of Lhx8 expression in vitro
10.1016/j.taap.2017.01.004 · 2017 · External reference
Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones
10.1210/er.2003-0030 · 2004 · External reference
The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders
10.1210/er.2010-0013 · 2011 · External reference
Continuous light exposure influences luteinization and luteal function of ovary in ICR mice
10.1111/jpi.12846 · 2023 · External reference
CCAAT/enhancer-binding proteins (C/EBP)-α and -β are essential for ovulation, luteinization, and the expression of key target genes
10.1210/me.2010-0318 · 2011 · External reference
Activation of Gq/11 in the mouse corpus luteum is required for parturition
10.1210/me.2014-1324 · 2015 · External reference
Scavenger receptor-B1 and luteal function in mice
10.1194/jlr.m006973 · 2010 · External reference
Intracycle variation in number of antral follicles stratified by size and in endocrine markers of ovarian reserve in women with normal ovulatory menstrual cycles
10.1002/uog.11226 · 2013 · External reference
Maturation of ovarian follicles: actions and interactions of pituitary and ovarian hormones on follicular cell differentiation
10.1152/physrev.1980.60.1.51 · 1980 · External reference
Regulated expression of Rhox8 in the mouse ovary: evidence for the role of progesterone and RHOX5 in granulosa cells
10.1095/biolreprod.112.103267 · 2013 · External reference
Lhcgr expression in granulosa cells: roles for PKA-phosphorylated β-catenin, TCF3, and FOXO1
10.1210/me.2013-1025 · 2013 · External reference
Knockdown of CYP19A1 in Buffalo Follicular Granulosa Cells Results in Increased Progesterone Secretion and Promotes Cell Proliferation
10.3389/fvets.2020.539496 · 2020 · External reference
Role of ERα in Mediating Female Uterine Transcriptional Responses to IGF1
10.1210/en.2017-00349 · 2017 · External reference
Research resource: whole-genome estrogen receptor α binding in mouse uterine tissue revealed by ChIP-seq
10.1210/me.2011-1311 · 2012 · External reference
Hormone-regulated transcriptomes: lessons learned from estrogen signaling pathways in breast cancer cells
10.1016/j.mce.2013.06.021 · 2014 · External reference
Estrogen Receptors and Endometriosis
10.3390/ijms21082815 · 2020 · External reference
Role for Growth Regulation by Estrogen in Breast Cancer 1 (GREB1) in Hormone-Dependent Cancers
10.3390/ijms19092543 · 2018 · External reference
