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References from Validation of the biological function and prognostic significance of AURKA in neuroblastoma. Local targets link to admitted publications; unresolved targets remain external evidence.
Neuroblastoma: Emerging trends in pathogenesis, diagnosis, and therapeutic targets
10.1016/j.jconrel.2023.04.001 · 2023 · External reference
Aurora kinase A, a synthetic lethal target for precision cancer medicine
10.1038/s12276-021-00635-6 · 2021 · External reference
Targeted AURKA degradation: Towards new therapeutic agents for neuroblastoma
10.1016/j.ejmech.2022.115033 · 2022 · External reference
Aurora kinase A is superior to Ki67 as a prognostic indicator of survival in neuroblastoma.
10.1111/his.12520 · 2015 · External reference
Silencing of AURKA augments the antitumor efficacy of the AURKA inhibitor MLN8237 on neuroblastoma cells
10.1186/s12935-019-1072-y · 2020 · External reference
Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma
10.1016/j.ejca.2020.05.010 · 2020 · External reference
A phase I trial of AT9283 (a selective inhibitor of aurora kinases) in children and adolescents with solid tumors: a Cancer Research UK study.
10.1158/1078-0432.ccr-14-1592 · 2014 · External reference
Unbiased split variable selection for random survival forests using maximally selected rank statistics.
10.1002/sim.7212 · 2017 · External reference
SELPLG Expression Was Potentially Correlated With Metastasis and Prognosis of Osteosarcoma.
10.3389/pore.2022.1610047 · 2022 · External reference
Effect of hypertension on pregnancy outcomes at UNRWA health centres in Gaza governorates: a comparative study
10.1016/s0140-6736(21)01512-9 · 2021 · External reference
Effective degrees of freedom of the Pearson’s correlation coefficient under autocorrelation.
10.1016/j.neuroimage.2019.05.011 · 2019 · External reference
GSEAplot: A Package for Customizing Gene Set Enrichment Analysis in R
10.1089/cmb.2020.0426 · 2021 · External reference
clusterProfiler: an R package for comparing biological themes among gene clusters
10.1089/omi.2011.0118 · 2012 · External reference
Molecular signatures database (MSigDB) 3.0.
10.1093/bioinformatics/btr260 · 2011 · External reference
GSVA: gene set variation analysis for microarray and RNA-seq data
10.1186/1471-2105-14-7 · 2013 · External reference
Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer
10.1016/j.immuni.2013.10.003 · 2013 · External reference
Inferring tumour purity and stromal and immune cell admixture from expression data
10.1038/ncomms3612 · 2013 · External reference
TISIDB: an integrated repository portal for tumor-immune system interactions
10.1093/bioinformatics/btz210 · 2019 · External reference
The STRING database in 2021: customizable protein-protein networks, and functional characterization of user-uploaded gene/measurement sets.
10.1093/nar/gkaa1074 · 2021 · External reference
RegNetwork: an integrated database of transcriptional and post-transcriptional regulatory networks in human and mouse.
2015 · External reference
pRRophetic: an R package for prediction of clinical chemotherapeutic response from tumor gene expression levels
10.1371/journal.pone.0107468 · 2014 · External reference
Exploration of the molecular mechanism of intercellular communication in paediatric neuroblastoma by single-cell sequencing
10.1038/s41598-023-47796-0 · 2023 · External reference
Western blotting: an introduction
10.1007/978-1-4939-2694-7_5 · 2015 · External reference
Impact of low-income public insurance on survival for children and young adults with bone and soft tissue sarcomas
10.1200/jco.2019.37.15_suppl.10037 · 2019 · External reference
The one-way ANOVA test explained.
10.7748/nr.2023.e1885 · 2023 · External reference
Bora and Aurora-A continue to activate Plk1 in mitosis
2014 · External reference
Molecular targeting therapies for neuroblastoma: Progress and challenges
10.1002/med.21750 · 2021 · External reference
The dual role of BI 2536, a small-molecule inhibitor that targets PLK1, in induction of apoptosis and attenuation of autophagy in neuroblastoma cells
10.7150/jca.33110 · 2020 · External reference
TPX2 is a prognostic marker and promotes cell proliferation in neuroblastoma
10.3892/ol.2022.13256 · 2022 · External reference
Targeting the Chromosomal Passenger Complex Subunit INCENP Induces Polyploidization, Apoptosis, and Senescence in Neuroblastoma
10.1158/0008-5472.can-19-0695 · 2019 · External reference
Integrated pan-cancer of AURKA expression and drug sensitivity analysis reveals increased expression of AURKA is responsible for drug resistance
10.1002/cam4.4161 · 2021 · External reference
Age, Diagnostic Category, Tumor Grade, and Mitosis-Karyorrhexis Index Are Independently Prognostic in Neuroblastoma: An INRG Project.
10.1200/jco.19.03285 · 2020 · External reference
Neuroblastomas in Eastern China: a retrospective series study of 275 cases in a regional center.
10.7717/peerj.5665 · 2018 · External reference
AURKA Identified as Potential Lung Cancer Marker through Comprehensive Bioinformatic Analysis and Experimental Verification
10.1615/critreveukaryotgeneexpr.2023046830 · 2023 · External reference
Aurora-A Kinase: A Potent Oncogene and Target for Cancer Therapy.
10.1002/med.21399 · 2016 · External reference
Targeting Aurora kinase-A downregulates cell proliferation and angiogenesis in neuroblastoma
10.1016/j.jpedsurg.2013.09.051 · 2014 · External reference
Neuroblastoma-Telomere maintenance, deregulated signaling transduction and beyond
10.1002/ijc.33839 · 2022 · External reference
Caffeine Potentiates Ethanol-Induced Neurotoxicity Through mTOR/p70S6K/4E-BP1 Inhibition in SH-SY5Y Cells.
10.1177/1091581819900150 · 2020 · External reference
Pan-Cancer Analysis of Immune Cell Infiltration Identifies a Prognostic Immune-Cell Characteristic Score (ICCS) in Lung Adenocarcinoma.
10.3389/fimmu.2020.01218 · 2020 · External reference
AURKA, as a potential prognostic biomarker, regulates autophagy and immune infiltration in nasopharyngeal carcinoma
10.1016/j.imbio.2022.152314 · 2023 · External reference
Akt inhibitor a-443654 interferes with mitotic progression by regulating aurora a kinase expression
10.1593/neo.08408 · 2008 · External reference
Bcl-xL anti-apoptotic network is dispensable for development and maintenance of CML but is required for disease progression where it represents a new therapeutic target
10.1038/leu.2013.151 · 2013 · External reference
Selective BCL-XL inhibition promotes apoptosis in combination with MLN8237 in medulloblastoma and pediatric glioblastoma cells
10.1093/neuonc/nox134 · 2018 · External reference
