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References from Identification of new fucosyltransferase-8 inhibitors: An integrated biochemical, biophysical, and computational approach. Local targets link to admitted publications; unresolved targets remain external evidence.
Prostate cancer progression after androgen deprivation therapy: mechanisms of castrate resistance and novel therapeutic approaches
10.1038/onc.2013.206 · 2013 · External reference
Impact of immune complex size and glycosylation on IgG binding to human FcγRs
10.4049/jimmunol.1200501 · 2013 · External reference
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Fucosyltransferase 8 as a functional regulator of nonsmall cell lung cancer
10.1073/pnas.1220425110 · 2013 · External reference
Gene expression of alpha1-6 fucosyltransferase in human hepatoma tissues: a possible implication for increased fucosylation of alpha-fetoprotein
10.1002/hep.510280408 · 1998 · External reference
Core fucosylation of E-cadherin enhances cell-cell adhesion in human colon carcinoma WiDr cells
10.1111/j.1349-7006.2009.01125.x · 2009 · External reference
Core fucosylation of copper transporter 1 plays a crucial role in cisplatin-resistance of epithelial ovarian cancer by regulating drug uptake
10.1002/mc.22971 · 2019 · External reference
FUT8 promotes breast cancer cell invasiveness by remodeling TGF-β receptor core fucosylation
10.1186/s13058-017-0904-8 · 2017 · External reference
A systems biology approach identifies FUT8 as a driver of melanoma metastasis
10.1016/j.ccell.2017.05.007 · 2017 · External reference
Expression of α1, 6-fucosyltransferase (FUT8) in papillary carcinoma of the thyroid: its linkage to biological aggressiveness and anaplastic transformation
10.1016/s0304-3835(03)00383-5 · 2003 · External reference
Fucosyltransferase 8 plays a crucial role in the invasion and metastasis of pancreatic ductal adenocarcinoma
10.1007/s00595-019-01953-z · 2020 · External reference
Glycans as biomarkers in prostate cancer
10.3390/ijms20061389 · 2019 · External reference
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The diverse contributions of fucose linkages in cancer
10.3390/cancers11091241 · 2019 · External reference
Overexpression of α (1,6) fucosyltransferase in the development of castration-resistant prostate cancer cells
10.1038/s41391-017-0016-7 · 2018 · External reference
Overexpression of α (1,6) fucosyltransferase associated with aggressive prostate cancer
10.1093/glycob/cwu051 · 2014 · External reference
Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
2021 · External reference
Overexpression of α (1,6) fucosyltransferase in the development of castration-resistant prostate cancer cells
10.1038/s41391-017-0016-7 · 2018 · External reference
Overexpression of α (1,6) fucosyltransferase associated with aggressive prostate cancer
10.1093/glycob/cwu051 · 2014 · External reference
Fluorinated rhamnosides inhibit cellular fucosylation
10.1038/s41467-021-27355-9 · 2021 · External reference
Abstract 5551: SGN-2FF: a small-molecule inhibitor of fucosylation modulates immune cell activity in preclinical models and demonstrates pharmacodynamic activity in early phase 1 analysis
10.1158/1538-7445.am2018-5551 · 2018 · External reference
Cellular fucosylation inhibitors based on fluorinated fucose-1-phosphates*
10.1002/chem.202005359 · 2021 · External reference
PC3 is a cell line characteristic of prostatic small cell carcinoma
10.1002/pros.21383 · 2011 · External reference
Human BJ fibroblasts is an alternative to mouse BALB/c 3T3 cells in in vitro neutral red uptake assay
10.1111/bcpt.12790 · 2017 · External reference
Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
10.1016/0022-1759(83)90303-4 · 1983 · External reference
Tetrazolium dyes as tools in cell biology: new insights into their cellular reduction
10.1016/s1387-2656(05)11004-7 · 2005 · External reference
Drug repurposing for the identification of new Bcl-2 inhibitors: In vitro, STD-NMR, molecular docking, and dynamic simulation studies
10.1016/j.lfs.2023.122181 · 2023 · External reference
Drugs repurposing: an approach to identify new hits against anticancer drug target TFIIH subunit p8
10.1016/j.bioorg.2022.105755 · 2022 · External reference
The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability
10.1038/nprot.2007.321 · 2007 · External reference
Saturation-transfer difference (STD) NMR: a simple and fast method for ligand screening and characterization of protein binding
10.1021/ed101169t · 2011 · External reference
Group epitope mapping by saturation transfer difference NMR to identify segments of a ligand in direct contact with a protein receptor
10.1021/ja0100120 · 2001 · External reference
Extra precision glide: docking and scoring incorporating a model of hydrophobic enclosure for protein-ligand complexes
10.1021/jm051256o · 2006 · External reference
End-point binding free energy calculation with MM/PBSA and MM/GBSA: strategies and applications in drug design
10.1021/acs.chemrev.9b00055 · 2019 · External reference
A hierarchical approach to all-atom protein loop prediction
10.1002/prot.10613 · 2004 · External reference
OPLS3e: extending force field coverage for drug-like small molecules
10.1021/acs.jctc.8b01026 · 2019 · External reference
Molecular dynamics: survey of methods for simulating the activity of proteins
10.1021/cr040426m · 2006 · External reference
In silico identification of promising new pyrazole derivative-based small molecules for modulating CRMP2, C-RAF, CYP17, VEGFR, C-KIT, and HDAC-application towards cancer therapeutics
10.3390/cimb44110361 · 2022 · External reference
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OPLS4: improving force field accuracy on challenging regimes of chemical space
10.1021/acs.jctc.1c00302 · 2021 · External reference
In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro
10.1038/nprot.2007.30 · 2007 · External reference
