Research graph
References from Retinal macrophage-like cell activation and ganglion cell layer thinning are associated with disability and MRI lesion burden in multiple sclerosis. Local targets link to admitted publications; unresolved targets remain external evidence.
Review of multiple sclerosis: Epidemiology, etiology, pathophysiology, and treatment
10.1097/md.0000000000037297 · 2024 · External reference
Rising prevalence of multiple sclerosis worldwide: Insights from the Atlas of MS, third edition
10.1177/1352458520970841 · 2020 · External reference
Diagnosis and Treatment of Multiple Sclerosis: A Review
10.1001/jama.2020.26858 · 2021 · External reference
Environmental and genetic risk factors for MS: an integrated review
10.1002/acn3.50862 · 2019 · External reference
Epidemiology and phenotypes of multiple sclerosis in the Middle East North Africa (MENA) region
2020 · External reference
Association of infections with multiple sclerosis in Gulf Cooperation Council countries: a review
10.1177/0300060519884151 · 2020 · External reference
Enhancement of neuroprotective and anti-edema action in mice ischemic stroke model using T3 loaded nanoparticles
10.55940/medphar202463 · 2024 · External reference
Origin of microglia: current concepts and past controversies
10.1101/cshperspect.a020537 · 2015 · External reference
10.1101/cshperspect.a020560
10.1101/cshperspect.a020560 · External reference
Progressive multiple sclerosis: pathology and pathogenesis
10.1038/nrneurol.2012.168 · 2012 · External reference
Microglial cell activation and proliferation precedes the onset of CNS autoimmunity
10.1002/jnr.20488 · 2005 · External reference
TNF alpha promotes proliferation of oligodendrocyte progenitors and remyelination
10.1038/nn738 · 2001 · External reference
Metalloproteinases in biology and pathology of the nervous system
10.1038/35081571 · 2001 · External reference
Microglia in the Retina: Roles in Development, Maturity, and Disease
10.1146/annurev-vision-091517-034425 · 2018 · External reference
An update on immunopathogenesis, diagnosis, and treatment of multiple sclerosis
10.1002/brb3.362 · 2015 · External reference
Multiple sclerosis: an immune or neurodegenerative disorder?
10.1146/annurev.neuro.30.051606.094313 · 2008 · External reference
Multiple Sclerosis: Pathogenesis, Symptoms, Diagnoses and Cell-Based Therapy
2017 · External reference
The role of microglia in multiple sclerosis
10.2147/ndt.s140634 · 2017 · External reference
Experimental autoimmune encephalomyelitis repressed by microglial paralysis
10.1038/nm1177 · 2005 · External reference
Modulation of microglial/macrophage activation by macrophage inhibitory factor (TKP) or tuftsin (TKPR) attenuates the disease course of experimental autoimmune encephalomyelitis
10.1186/1471-2172-8-10 · 2007 · External reference
Changes in murine hyalocytes are valuable early indicators of ocular disease
10.1167/iovs.11-8601 · 2012 · External reference
Description of Macrophage-Like Cells in Active Ocular Toxoplasmosis
10.1080/09273948.2023.2263073 · 2024 · External reference
In Vivo Visualization of Macrophage-Like Cells in Patients with Uveitis by Use of
10.1080/09273948.2023.2254369 · 2024 · External reference
Vitreoretinal Interface Cells Correlate In Vivo With Uveitis Activity and Decrease With Anti-Inflammatory Treatment
10.1167/tvst.13.5.15 · 2024 · External reference
Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria
10.1016/s1474-4422(17)30470-2 · 2018 · External reference
The OSCAR-IB consensus criteria for retinal OCT quality assessment
10.1371/journal.pone.0034823 · 2012 · External reference
Role of Microglial Cells in the Pathophysiology of MS: Synergistic or Antagonistic?
10.3390/ijms24031861 · 2023 · External reference
Microglia in multiple sclerosis: friend or foe?
10.3389/fimmu.2020.00374 · 2020 · External reference
Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation
10.1186/1742-2094-9-156 · 2012 · External reference
Neuroinflammation following disease modifying therapy in multiple sclerosis: A pilot positron emission tomography study
10.1016/j.jns.2017.12.004 · 2018 · External reference
Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons
10.1007/s00401-013-1082-0 · 2013 · External reference
Glial pathology and retinal neurotoxicity in the anterior visual pathway in experimental autoimmune encephalomyelitis
10.1186/s40478-019-0767-6 · 2019 · External reference
Retinal and Brain Microglia in Multiple Sclerosis and Neurodegeneration
10.3390/cells10061507 · 2021 · External reference
Proliferative diabetic retinopathy and diabetic macular edema are two factors that increase macrophage-like cell density characterized by en face optical coherence tomography
10.1186/s12886-023-02794-8 · 2023 · External reference
Macrophage-like Cells Are Increased in Patients with Vision-Threatening Diabetic Retinopathy and Correlate with Macular Edema
10.3390/diagnostics12112793 · 2022 · External reference
Distinctive waves of innate immune response in the retina in experimental autoimmune encephalomyelitis
10.1172/jci.insight.149228 · 2021 · External reference
Imaging of Macrophage-Like Cells in Living Human Retina Using Clinical OCT
10.1167/iovs.61.6.48 · 2020 · External reference
Multiple enface image averaging for enhanced optical coherence tomography angiography imaging
2018 · External reference
Trans-retinal cellular imaging with multimodal adaptive optics
10.1364/boe.9.004246 · 2018 · External reference
Macrophage-like Cells Characterized by En Face Optical Coherence Tomography was Associated with Fluorescein Vascular Leakage in Behçet’s Uveitis
10.1080/09273948.2022.2080719 · 2023 · External reference
Clinical and pathological insights into the dynamic nature of the white matter multiple sclerosis plaque
10.1002/ana.24497 · 2015 · External reference
The relation between inflammation and neurodegeneration in multiple sclerosis brains
10.1093/brain/awp070 · 2009 · External reference
Microglia in multiple sclerosis: Protectors turn destroyers
10.1016/j.neuron.2022.06.023 · 2022 · External reference
Pathology and pathogenesis of progressive multiple sclerosis: concepts and controversies
2023 · External reference
Association of Chronic Active Multiple Sclerosis Lesions With Disability In Vivo
10.1001/jamaneurol.2019.2399 · 2019 · External reference
The macular retinal ganglion cell layer as a biomarker for diagnosis and prognosis in multiple sclerosis: A deep learning approach
10.1111/aos.15722 · 2024 · External reference
Gray matter microglial activation in relapsing vs progressive MS: A [F-18]PBR06-PET study
10.1212/nxi.0000000000000587 · 2019 · External reference
Microglia activation in multiple sclerosis black holes predicts outcome in progressive patients: an in vivo [(11)C](R)-PK11195-PET pilot study
10.1016/j.nbd.2014.01.018 · 2014 · External reference
Chronic demyelination exacerbates neuroaxonal loss in patients with MS with unilateral optic neuritis
2020 · External reference
Primary retinal pathology in multiple sclerosis as detected by optical coherence tomography
10.1093/brain/awq346 · 2011 · External reference
Primary retinal pathology in multiple sclerosis as detected by optical coherence tomography
10.1093/brain/awr095 · 2011 · External reference
Visual dysfunction in multiple sclerosis correlates better with optical coherence tomography derived estimates of macular ganglion cell layer thickness than peripapillary retinal nerve fiber layer thickness
10.1177/1352458511418630 · 2011 · External reference
Degeneration of retinal layers in multiple sclerosis subtypes quantified by optical coherence tomography
10.1177/1352458512439237 · 2012 · External reference
Loss of Cells in the Retinal Ganglion Cell Layer as an Early Indication of Neurodegeneration in Multiple Sclerosis
10.31083/j.jin2307129 · 2024 · External reference
Cellular-Level Visualization of Retinal Pathology in Multiple Sclerosis With Adaptive Optics
10.1167/iovs.64.14.21 · 2023 · External reference
Retinal layer thickness predicts disability accumulation in early relapsing multiple sclerosis
10.1111/ene.15718 · 2023 · External reference
Retinal ganglion cell analysis in multiple sclerosis and optic neuritis: a systematic review and meta-analysis
10.1007/s00415-017-8531-y · 2017 · External reference
Association of Spectral-Domain OCT With Long-term Disability Worsening in Multiple Sclerosis
10.1212/wnl.0000000000011788 · 2021 · External reference
Visual Function and Disability Are Associated With Focal Thickness Reduction of the Ganglion Cell-Inner Plexiform Layer in Patients With Multiple Sclerosis
10.1167/iovs.18-25809 · 2019 · External reference
Minimal neuropsychological assessment of MS patients: a consensus approach
10.1076/clin.16.3.381.13859 · 2002 · External reference
Validity of the timed 25-foot walk as an ambulatory performance outcome measure for multiple sclerosis
10.1177/1352458517690823 · 2017 · External reference
MRI FLAIR lesion segmentation in multiple sclerosis: Does automated segmentation hold up with manual annotation?
10.1016/j.nicl.2016.11.020 · 2017 · External reference
