Research graph
References from The cGAS-STING pathway in acute myocardial infarction: Biomarker discovery and mechanistic insights. Local targets link to admitted publications; unresolved targets remain external evidence.
Not all heart attacks are created equal: thinking differently about acute myocardial infarction in the young
10.14797/mdcvj.345 · 2021 · External reference
Global burden of cardiovascular diseases and risks, 1990-2022
10.1016/j.jacc.2023.11.007 · 2023 · External reference
2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines
10.1016/j.jacc.2024.11.009 · 2025 · External reference
Acute myocardial infarction biosensor: a review from bottom up
10.1016/j.cpcardiol.2020.100739 · 2021 · External reference
COPD and acute myocardial infarction
10.1183/16000617.0139-2019 · 2020 · External reference
cGAS-STING signaling
2022 · External reference
cGAS-STING: mechanisms and therapeutic opportunities
10.1007/s11427-024-2808-3 · 2025 · External reference
cGAS-STING signaling in cardiovascular diseases
10.3389/fimmu.2024.1402817 · 2024 · External reference
The cGAS-STING pathway in atherosclerosis
10.3389/fcvm.2025.1550930 · 2025 · External reference
Cellular functions of cGAS-STING signaling
10.1016/j.tcb.2022.11.001 · 2023 · External reference
Differential Expression Enrichment Tool (DEET): an interactive atlas of human differential gene expression
2023 · External reference
NCBI GEO: archive for functional genomics data sets--update
2013 · External reference
A diagnostic model for sepsis-induced acute lung injury using a consensus machine learning approach and its therapeutic implications
10.1186/s12967-023-04499-4 · 2023 · External reference
Identification of potential circadian rhythm-related hub genes and immune infiltration in preeclampsia through bioinformatics analysis
10.1080/10641955.2025.2559734 · 2025 · External reference
clusterProfiler: an R package for comparing biological themes among gene clusters
10.1089/omi.2011.0118 · 2012 · External reference
The STRING database in 2017: quality-controlled protein-protein association networks, made broadly accessible
10.1093/nar/gkw937 · 2017 · External reference
cytoHubba: identifying hub objects and sub-networks from complex interactome
2014 · External reference
Multiple correlations and Bonferroni’s correction
10.1016/s0006-3223(98)00043-2 · 1998 · External reference
Identification of predictors for neurological outcome after cardiac arrest in peripheral blood mononuclear cells through integrated bioinformatics analysis and machine learning
10.1007/s10142-023-01016-0 · 2023 · External reference
Combination of exhaled volatile organic compounds with serum biomarkers predicts respiratory infection severity
10.1080/25310429.2025.2477911 · 2025 · External reference
Inflammatory gene signature identified by machine algorithms reveals novel biomarkers of coronary artery disease
10.2147/jir.s496046 · 2025 · External reference
The prognostic landscape of genes and infiltrating immune cells across human cancers
10.1038/nm.3909 · 2015 · External reference
Comprehensive characterization of cytokines in patients under extracorporeal membrane oxygenation: evidence from integrated bulk and single-cell rna sequencing data using multiple machine learning approaches
10.1097/shk.0000000000002425 · 2025 · External reference
Colchicine in acute myocardial infarction
10.1056/nejmoa2405922 · 2025 · External reference
Targeting inflammation in atherosclerosis - from experimental insights to the clinic
10.1038/s41573-021-00198-1 · 2021 · External reference
Autophagy and mitophagy in cardiovascular disease
10.1161/circresaha.117.311082 · 2017 · External reference
Efficacy and safety of low-dose colchicine after myocardial infarction
10.1056/nejmoa1912388 · 2019 · External reference
2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines
2025 · External reference
Regulation of the cGAS-STING pathway
10.1146/annurev-immunol-101721-032910 · 2025 · External reference
IRF3 and type I interferons fuel a fatal response to myocardial infarction
10.1038/nm.4428 · 2017 · External reference
Cytosolic DNA sensing promotes macrophage transformation and governs myocardial ischemic injury
10.1161/circulationaha.117.031046 · 2018 · External reference
PFKFB3 inhibitor 3PO reduces cardiac remodeling after myocardial infarction by regulating the TGF-beta1/SMAD2/3 pathway
10.3390/biom13071072 · 2023 · External reference
Upregulation of glycolytic enzyme PFKFB3 by deubiquitinase OTUD4 promotes cardiac fibrosis post myocardial infarction
10.1007/s00109-023-02323-6 · 2023 · External reference
Inhibition of PFKFB3 expression stimulates macrophage-mediated lymphangiogenesis post-acute myocardial infarction
10.31083/j.fbl2811277 · 2023 · External reference
Immunometabolic endothelial phenotypes: integrating inflammation and glucose metabolism
10.1161/circresaha.120.318805 · 2021 · External reference
Endothelial nucleotide-binding oligomerization domain-like receptor protein 3 inflammasome regulation in atherosclerosis
10.1093/cvr/cvae071 · 2024 · External reference
Ablation of endothelial Pfkfb3 protects mice from acute lung injury in LPS-induced endotoxemia
10.1016/j.phrs.2019.104292 · 2019 · External reference
Gene-dosage effect of Pfkfb3 on monocyte/macrophage biology in atherosclerosis
10.1111/bph.15926 · 2022 · External reference
Ischemia/reperfusion activates myocardial innate immune response: the key role of the toll-like receptor
10.3389/fphys.2014.00496 · 2014 · External reference
Systemic toll-like receptor and interleukin-18 pathway activation in patients with acute ST elevation myocardial infarction
10.1016/j.yjmcc.2013.12.021 · 2014 · External reference
Myocardial ischemia/reperfusion injury is mediated by leukocytic toll-like receptor-2 and reduced by systemic administration of a novel anti-toll-like receptor-2 antibody
10.1161/circulationaha.109.880187 · 2010 · External reference
Treatment with OPN-305, a humanized anti-Toll-Like receptor-2 antibody, reduces myocardial ischemia/reperfusion injury in pigs
10.1161/circinterventions.111.967596 · 2012 · External reference
Upregulation of glycolytic enzyme PFKFB3 by deubiquitinase OTUD4 promotes cardiac fibrosis post myocardial infarction
10.1007/s00109-023-02323-6 · ExternalCitation · doi-reference
Identification of predictors for neurological outcome after cardiac arrest in peripheral blood mononuclear cells through integrated bioinformatics analysis and machine learning
10.1007/s10142-023-01016-0 · ExternalCitation · doi-reference
cGAS-STING: mechanisms and therapeutic opportunities
10.1007/s11427-024-2808-3 · ExternalCitation · doi-reference
Acute myocardial infarction biosensor: a review from bottom up
10.1016/j.cpcardiol.2020.100739 · ExternalCitation · doi-reference
Global burden of cardiovascular diseases and risks, 1990-2022
10.1016/j.jacc.2023.11.007 · ExternalCitation · doi-reference
2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines
10.1016/j.jacc.2024.11.009 · ExternalCitation · doi-reference
Ablation of endothelial Pfkfb3 protects mice from acute lung injury in LPS-induced endotoxemia
10.1016/j.phrs.2019.104292 · ExternalCitation · doi-reference
Cellular functions of cGAS-STING signaling
10.1016/j.tcb.2022.11.001 · ExternalCitation · doi-reference
Systemic toll-like receptor and interleukin-18 pathway activation in patients with acute ST elevation myocardial infarction
10.1016/j.yjmcc.2013.12.021 · ExternalCitation · doi-reference
Multiple correlations and Bonferroni’s correction
10.1016/s0006-3223(98)00043-2 · ExternalCitation · doi-reference
The prognostic landscape of genes and infiltrating immune cells across human cancers
10.1038/nm.3909 · ExternalCitation · doi-reference
IRF3 and type I interferons fuel a fatal response to myocardial infarction
10.1038/nm.4428 · ExternalCitation · doi-reference
Targeting inflammation in atherosclerosis - from experimental insights to the clinic
10.1038/s41573-021-00198-1 · ExternalCitation · doi-reference
Efficacy and safety of low-dose colchicine after myocardial infarction
10.1056/nejmoa1912388 · ExternalCitation · doi-reference
Colchicine in acute myocardial infarction
10.1056/nejmoa2405922 · ExternalCitation · doi-reference
Identification of potential circadian rhythm-related hub genes and immune infiltration in preeclampsia through bioinformatics analysis
10.1080/10641955.2025.2559734 · ExternalCitation · doi-reference
Combination of exhaled volatile organic compounds with serum biomarkers predicts respiratory infection severity
10.1080/25310429.2025.2477911 · ExternalCitation · doi-reference
clusterProfiler: an R package for comparing biological themes among gene clusters
10.1089/omi.2011.0118 · ExternalCitation · doi-reference
Endothelial nucleotide-binding oligomerization domain-like receptor protein 3 inflammasome regulation in atherosclerosis
10.1093/cvr/cvae071 · ExternalCitation · doi-reference
The STRING database in 2017: quality-controlled protein-protein association networks, made broadly accessible
10.1093/nar/gkw937 · ExternalCitation · doi-reference
Comprehensive characterization of cytokines in patients under extracorporeal membrane oxygenation: evidence from integrated bulk and single-cell rna sequencing data using multiple machine learning approaches
10.1097/shk.0000000000002425 · ExternalCitation · doi-reference
Gene-dosage effect of Pfkfb3 on monocyte/macrophage biology in atherosclerosis
10.1111/bph.15926 · ExternalCitation · doi-reference
Regulation of the cGAS-STING pathway
10.1146/annurev-immunol-101721-032910 · ExternalCitation · doi-reference
Treatment with OPN-305, a humanized anti-Toll-Like receptor-2 antibody, reduces myocardial ischemia/reperfusion injury in pigs
10.1161/circinterventions.111.967596 · ExternalCitation · doi-reference
Autophagy and mitophagy in cardiovascular disease
10.1161/circresaha.117.311082 · ExternalCitation · doi-reference
Immunometabolic endothelial phenotypes: integrating inflammation and glucose metabolism
10.1161/circresaha.120.318805 · ExternalCitation · doi-reference
Myocardial ischemia/reperfusion injury is mediated by leukocytic toll-like receptor-2 and reduced by systemic administration of a novel anti-toll-like receptor-2 antibody
10.1161/circulationaha.109.880187 · ExternalCitation · doi-reference
Cytosolic DNA sensing promotes macrophage transformation and governs myocardial ischemic injury
10.1161/circulationaha.117.031046 · ExternalCitation · doi-reference
COPD and acute myocardial infarction
10.1183/16000617.0139-2019 · ExternalCitation · doi-reference
A diagnostic model for sepsis-induced acute lung injury using a consensus machine learning approach and its therapeutic implications
10.1186/s12967-023-04499-4 · ExternalCitation · doi-reference
Not all heart attacks are created equal: thinking differently about acute myocardial infarction in the young
10.14797/mdcvj.345 · ExternalCitation · doi-reference
Inflammatory gene signature identified by machine algorithms reveals novel biomarkers of coronary artery disease
10.2147/jir.s496046 · ExternalCitation · doi-reference
Inhibition of PFKFB3 expression stimulates macrophage-mediated lymphangiogenesis post-acute myocardial infarction
10.31083/j.fbl2811277 · ExternalCitation · doi-reference
The cGAS-STING pathway in atherosclerosis
10.3389/fcvm.2025.1550930 · ExternalCitation · doi-reference
cGAS-STING signaling in cardiovascular diseases
10.3389/fimmu.2024.1402817 · ExternalCitation · doi-reference
Ischemia/reperfusion activates myocardial innate immune response: the key role of the toll-like receptor
10.3389/fphys.2014.00496 · ExternalCitation · doi-reference
PFKFB3 inhibitor 3PO reduces cardiac remodeling after myocardial infarction by regulating the TGF-beta1/SMAD2/3 pathway
10.3390/biom13071072 · ExternalCitation · doi-reference
