Research graph
References from Spatial organization of HPV-associated immune programs across tissue compartments in oropharyngeal cancer. Local targets link to admitted publications; unresolved targets remain external evidence.
Human papillomavirus and survival of patients with oropharyngeal cancer
10.1056/nejmoa0912217 · 2010 · External reference
Human papillomavirus and rising oropharyngeal cancer incidence in the United States
10.1200/jco.2011.36.4596 · 2011 · External reference
Epidemiology of human papillomavirus-positive head and neck squamous cell carcinoma
10.1200/jco.2015.61.6995 · 2015 · External reference
Tertiary lymphoid structures improve immunotherapy and survival in melanoma
10.1038/s41586-019-1914-8 · 2020 · External reference
HPV-associated oropharyngeal cancer: Epidemiology, molecular biology and clinical management
10.1038/s41571-022-00603-7 · 2022 · External reference
The immune microenvironment of HPV-positive and HPV-negative oropharyngeal squamous cell carcinoma: A multiparametric quantitative and spatial analysis unveils a rationale to target treatment-naïve tumors with immune checkpoint inhibitors
10.1186/s13046-022-02481-4 · 2022 · External reference
Tumour-infiltrating lymphocytes predict for outcome in HPV-positive oropharyngeal cancer
10.1038/bjc.2013.639 · 2014 · External reference
Immune landscape of viral- and carcinogen-driven head and neck cancer
10.1016/j.immuni.2019.11.014 · 2020 · External reference
Treatment-naïve HPV+ head and neck cancers display a T-cell-inflamed phenotype distinct from their HPV- counterparts that has implications for immunotherapy
10.1080/2162402x.2018.1498439 · 2018 · External reference
Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy
10.1038/nature19330 · 2016 · External reference
Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade
10.1038/s41590-019-0312-6 · 2019 · External reference
Intratumoral Tcf1+PD-1+CD8+ T cells with stem-like properties promote tumor control in response to vaccination and checkpoint blockade immunotherapy
10.1016/j.immuni.2018.12.021 · 2019 · External reference
The immune landscape of cancer
10.1016/j.immuni.2018.03.023 · 2018 · External reference
B cells and tertiary lymphoid structures promote immunotherapy response
10.1038/s41586-019-1922-8 · 2020 · External reference
Tertiary lymphoid structures in the era of cancer immunotherapy
10.1038/s41568-019-0144-6 · 2019 · External reference
Exploratory spatial transcriptomic profiling of peritumoral Th2 immune polarization in HPV-positive oropharyngeal cancer
10.3389/fonc.2025.1732480 · 2025 · External reference
Comprehensive genomic characterization of head and neck squamous cell carcinomas
10.1038/nature14129 · 2015 · External reference
Analysis of The Cancer Genome Atlas sequencing data reveals novel properties of the human papillomavirus 16 genome in head and neck squamous cell carcinoma
10.18632/oncotarget.15179 · 2017 · External reference
Establishment and validation of exhausted CD8+ T cell feature as a prognostic model of HCC
10.3389/fimmu.2023.1166052 · 2023 · External reference
The Molecular Signatures Database (MSigDB) hallmark gene set collection
10.1016/j.cels.2015.12.004 · 2015 · External reference
GSVA: Gene set variation analysis for microarray and RNA-seq data
10.1186/1471-2105-14-7 · 2013 · External reference
Immune-related gene expression profile at peritumoral tonsillar tissue is modified by oropharyngeal cancer nodal status
10.1016/j.ajpath.2023.04.010 · 2023 · External reference
Advances in mixed cell deconvolution enable quantification of cell types in spatial transcriptomic data
10.1038/s41467-022-28020-5 · 2022 · External reference
Spatial landscapes of cancers: Insights and opportunities
10.1038/s41571-024-00926-7 · 2024 · External reference
Spatial profiling technologies illuminate the tumor microenvironment
10.1016/j.ccell.2023.01.010 · 2023 · External reference
Mature tertiary lymphoid structures evoke intra-tumoral T and B cell responses via progenitor exhausted CD4+ T cells in head and neck cancer
10.1038/s41467-025-59341-w · 2025 · External reference
Spatial profiling of HPV-stratified head and neck squamous cell carcinoma reveals distinct immune niches and microenvironmental architectures
10.1186/s12967-025-07280-x · 2025 · External reference
Decoding the tumor microenvironment with spatial technologies
10.1038/s41590-023-01678-9 · 2023 · External reference
Stem-like CD8+ T cells in cancer
10.3389/fimmu.2024.1426418 · 2024 · External reference
Mature tertiary lymphoid structures linked to HPV status and anti-PD-1 based chemoimmunotherapy response in head and neck squamous cell carcinoma
10.1080/2162402x.2025.2528109 · 2025 · External reference
