References

The CK1 Family: Contribution to Cellular Stress Response and Its Role in Carcinogenesis

10.3389/fonc.2014.00096 · 2014 · External reference

Casein kinase 1delta functions at the centrosome and Golgi to promote ciliogenesis

10.1091/mbc.e13-10-0598 · 2014 · External reference

Casein kinase 1 delta functions at the centrosome to mediate Wnt-3a-dependent neurite outgrowth

10.1083/jcb.201011111 · 2011 · External reference

Interaction of CK1delta with gammaTuSC ensures proper microtubule assembly and spindle positioning

10.1091/mbc.e14-12-1627 · 2015 · External reference

The FAM83 family of proteins: from pseudo-PLDs to anchors for CK1 isoforms

10.1042/bst20160277 · 2018 · External reference

FRQ-CK1 Interaction Underlies Temperature Compensation of the Neurospora Circadian Clock

2021 · External reference

Interaction of casein kinase 1 delta (CK1 delta) with the light chain LC2 of microtubule associated protein 1A (MAP1A)

10.1016/j.bbamcr.2005.05.004 · 2005 · External reference

The casein kinase 1 family: participation in multiple cellular processes in eukaryotes

10.1016/j.cellsig.2004.12.011 · 2005 · External reference

Biological functions of casein kinase 1 isoforms and putative roles in tumorigenesis

10.1186/1476-4598-13-231 · 2014 · External reference

Casein kinase 1α: biological mechanisms and theranostic potential

10.1186/s12964-018-0236-z · 2018 · External reference

The flaviviral methyltransferase is a substrate of Casein Kinase 1

10.1016/j.virusres.2009.01.002 · 2009 · External reference

Dangerous Duplicity: The Dual Functions of Casein Kinase 1 in Parasite Biology and Host Subversion

10.3389/fcimb.2021.655700 · 2021 · External reference

Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival

10.1038/s41467-021-21360-8 · 2021 · External reference

Identification of a secreted casein kinase 1 in Leishmania donovani: effect of protein over expression on parasite growth and virulence

10.1371/journal.pone.0079287 · 2013 · External reference

An exosome-based secretion pathway is responsible for protein export from Leishmania and communication with macrophages

10.1242/jcs.056465 · 2010 · External reference

Exosome Secretion by the Parasitic Protozoan Leishmania within the Sand Fly Midgut

10.1016/j.celrep.2015.09.058 · 2015 · External reference

Structure, regulation, and (patho-)physiological functions of the stress-induced protein kinase CK1 delta (CSNK1D)

10.1016/j.gene.2019.144005 · 2019 · External reference

Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection

10.1128/aac.02022-13 · 2014 · External reference

Identification of the Host Substratome of Leishmania-Secreted Casein Kinase 1 Using a SILAC-Based Quantitative Mass Spectrometry Assay

10.3389/fcell.2021.800098 · 2022 · External reference

Leishmania donovani 90 kD Heat Shock Protein - Impact of Phosphosites on Parasite Fitness, Infectivity and Casein Kinase Affinity

10.1038/s41598-019-41640-0 · 2019 · External reference

Casein kinase 1.2 over expression restores stress resistance to Leishmania donovani HSP23 null mutants

10.1038/s41598-020-72724-x · 2020 · External reference

Mammalian casein kinase 1alpha and its leishmanial ortholog regulate stability of IFNAR1 and type I interferon signaling

10.1128/mcb.00478-09 · 2009 · External reference

Characterisation of Casein Kinase 1.1 in Leishmania donovani Using the CRISPR Cas9 Toolkit

10.1155/2017/4635605 · 2017 · External reference

BILBO1 is a scaffold protein of the flagellar pocket collar in the pathogen Trypanosoma brucei

10.1371/journal.ppat.1004654 · 2015 · External reference

Expression of a mutant form of Leishmania donovani centrin reduces the growth of the parasite

10.1074/jbc.m106806200 · 2001 · External reference

Intraflagellar transport and functional analysis of genes required for flagellum formation in trypanosomes

10.1091/mbc.e07-08-0749 · 2008 · External reference

Assembly of the paraflagellar rod and the flagellum attachment zone complex during the Trypanosoma brucei cell cycle

10.1111/j.1550-7408.1999.tb04592.x · 1999 · External reference

Diversification of function by different isoforms of conventionally shared RNA polymerase subunits

10.1091/mbc.e06-09-0841 · 2007 · External reference

Fiji: an open-source platform for biological-image analysis

10.1038/nmeth.2019 · 2012 · External reference

From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity

10.1128/aac.00021-16 · 2016 · External reference

High content analysis of primary macrophages hosting proliferating Leishmania amastigotes: application to anti-leishmanial drug discovery

10.1371/journal.pntd.0002154 · 2013 · External reference

myProMS, a web server for management and validation of mass spectrometry-based proteomic data

10.1002/pmic.200600784 · 2007 · External reference

Fast and Accurate Protein False Discovery Rates on Large-Scale Proteomics Data Sets with Percolator 3.0

10.1007/s13361-016-1460-7 · 2016 · External reference

MassChroQ: a versatile tool for mass spectrometry quantification

10.1002/pmic.201100120 · 2011 · External reference

The PRIDE database at 20 years: 2025 update

10.1093/nar/gkae1011 · 2025 · External reference

PANTHER version 16: a revised family classification, tree-based classification tool, enhancer regions and extensive API

2021 · External reference

TriTrypDB: a functional genomic resource for the Trypanosomatidae

10.1093/nar/gkp851 · 2010 · External reference

The STRING database in 2023: protein-protein association networks and functional enrichment analyses for any sequenced genome of interest

10.1093/nar/gkac1000 · 2023 · External reference

TrypTag.org: A Trypanosome Genome-wide Protein Localisation Resource

10.1016/j.pt.2016.10.009 · 2017 · External reference

STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

10.1093/nar/gky1131 · 2019 · External reference

Cytoscape: a software environment for integrated models of biomolecular interaction networks

10.1101/gr.1239303 · 2003 · External reference

Unresolved reference

External reference

Author correction: SciPy 1.0: fundamental algorithms for scientific computing in Python

10.1038/s41592-020-0772-5 · 2020 · External reference

The estimation and significance of the logarithm of a ratio of frequencies

10.1111/j.1469-1809.1955.tb01285.x · 1956 · External reference

On Estimating Binomial Response Relations

10.1093/biomet/43.3-4.461 · 1956 · External reference

Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

10.1111/j.2517-6161.1995.tb02031.x · 1995 · External reference

Unresolved reference

2010 · External reference

10.25080/majora-92bf1922-00a

10.25080/majora-92bf1922-00a · 2010 · External reference

Array programming with NumPy

10.1038/s41586-020-2649-2 · 2020 · External reference

Matplotlib: A 2D Graphics Environment

10.1109/mcse.2007.55 · 2007 · External reference

Adaptin evolution in kinetoplastids and emergence of the variant surface glycoprotein coat in African trypanosomatids

10.1016/j.ympev.2013.01.002 · 2013 · External reference

Impact of inherent biases built into proteomic techniques: Proximity labeling and affinity capture compared

10.1016/j.jbc.2022.102726 · 2023 · External reference

Nup53p is a target of two mitotic kinases, Cdk1p and Hrr25p

10.1111/j.1600-0854.2007.00559.x · 2007 · External reference

Nucleolar division in the promastigote stage of Leishmania major parasite: A Nop56 point of view

10.1155/2018/1641839 · 2018 · External reference

Nucleolar accumulation of RNA binding proteins induced by Actinomycin D is functional in Trypanosoma cruzi and Leishmania mexicana but not in T. brucei

10.1371/journal.pone.0024184 · 2011 · External reference

Immunocytochemical detection of DNA and RNA in endosymbiont-bearing trypanosomatids

10.1016/s0378-1097(03)00087-9 · 2003 · External reference

The nucleolus: Structure and function

10.1007/978-3-319-38882-3_2 · 2016 · External reference

Identification of factors involved in ribosome assembly in the protozoan parasite Leishmania major

10.1016/j.actatropica.2022.106315 · 2022 · External reference

Site-specific ribose methylation of preribosomal RNA: a novel function for small nucleolar RNAs

10.1016/s0092-8674(00)81308-2 · 1996 · External reference

Purified box C/D snoRNPs are able to reproduce site-specific 2’-O-methylation of target RNA in vitro

10.1128/mcb.22.19.6663-6668.2002 · 2002 · External reference

Architecture of the Trypanosoma brucei nucleus during interphase and mitosis

10.1007/s004120050402 · 2000 · External reference

A twinfilin-like protein coordinates karyokinesis by influencing mitotic spindle elongation and DNA replication in Leishmania

10.1111/mmi.13310 · 2016 · External reference

Casein kinase 1 isoform 2 is essential for bloodstream form Trypanosoma brucei

10.1016/j.molbiopara.2009.03.001 · 2009 · External reference

Faithful chromosome segregation in Trypanosoma brucei requires a cohort of divergent spindle-associated proteins with distinct functions

10.1093/nar/gky557 · 2018 · External reference

Identification and characterization of a cell division-regulating kinase AKB1 (associated kinase of Trypanosoma brucei 14-3-3) through proteomics study of the Tb14-3-3 binding proteins

10.1093/jb/mvv018 · 2015 · External reference

A cytoskeletal protein complex is essential for division of intracellular amastigotes of Leishmania mexicana

10.1074/jbc.ra120.014065 · 2020 · External reference

Biogenesis of the mitochondrial DNA inheritance machinery in the mitochondrial outer membrane of Trypanosoma brucei

10.1371/journal.ppat.1006808 · 2017 · External reference

Basal body structure and cell cycle-dependent biogenesis in Trypanosoma brucei

10.1186/s13630-016-0023-7 · 2016 · External reference

Centrin1 is required for organelle segregation and cytokinesis in Trypanosoma brucei

10.1091/mbc.e07-01-0022 · 2007 · External reference

Centrin4 coordinates cell and nuclear division in T. brucei

10.1242/jcs.030643 · 2008 · External reference

A comparative proteomic analysis reveals a new bi-lobe protein required for bi-lobe duplication and cell division in Trypanosoma brucei

10.1371/journal.pone.0009660 · 2010 · External reference

Dealing with several flagella in the same cell

10.1111/cmi.13162 · 2020 · External reference

Proteomic analysis of intact flagella of procyclic Trypanosoma brucei cells identifies novel flagellar proteins with unique sub-localization and dynamics

10.1074/mcp.m113.033357 · 2014 · External reference

Genetic dissection of a Leishmania flagellar proteome demonstrates requirement for directional motility in sand fly infections

2018 · External reference

Application of phosphoproteomics to find targets of casein kinase 1 in the flagellum of chlamydomonas

10.1155/2012/581460 · 2012 · External reference

Mycobacterium tuberculosis virulence is mediated by PtpA dephosphorylation of human vacuolar protein sorting 33B

10.1016/j.chom.2008.03.008 · 2008 · External reference

Low-complexity regions within protein sequences have position-dependent roles

10.1186/1752-0509-4-43 · 2010 · External reference

SMART, a simple modular architecture research tool: identification of signaling domains

10.1073/pnas.95.11.5857 · 1998 · External reference

Casein kinase TbCK1.2 regulates division of kinetoplast DNA, and movement of basal bodies in the African trypanosome

10.1371/journal.pone.0249908 · 2021 · External reference

CK1δ and CK1ε are components of human 40S subunit precursors required for cytoplasmic 40S maturation

2014 · External reference

Hrr25/CK1δ-directed release of Ltv1 from pre-40S ribosomes is necessary for ribosome assembly and cell growth

10.1083/jcb.201409056 · 2015 · External reference

An essential cell cycle-regulated nucleolar protein relocates to the mitotic spindle where it is involved in mitotic progression in Trypanosoma brucei

10.1074/jbc.m700780200 · 2007 · External reference

Casein kinase I is anchored on axonemal doublet microtubules and regulates flagellar dynein phosphorylation and activity

10.1074/jbc.m002134200 · 2000 · External reference

Regulation of dynein-driven microtubule sliding by the axonemal protein kinase CK1 in Chlamydomonas flagella

10.1083/jcb.200906168 · 2009 · External reference

Five-layer systems analysis of Leishmania stage differentiation reveals an essential role for protein degradation in parasite development

10.7554/elife.111115.3 · 2026 · External reference

Leishmania donovani inhibits macrophage apoptosis and pro-inflammatory response through AKT-mediated regulation of β-catenin and FOXO-1

10.1038/cdd.2016.101 · 2016 · External reference

Leishmania: manipulation of signaling pathways to inhibit host cell apoptosis

2021 · External reference

How to master the host immune system? Leishmania parasites have the solutions!

10.1093/intimm/dxx075 · 2018 · External reference

Proteomic-based approach to gain insight into reprogramming of THP-1 cells exposed to Leishmania donovani over an early temporal window

10.1128/iai.02833-14 · 2015 · External reference

The m6A reader IGF2BP2 directs immune-metabolic reprogramming in Leishmania amazonensis-infected macrophages

2024 · External reference

Leishmania infantum modulates host macrophage mitochondrial metabolism by hijacking the SIRT1-AMPK axis

10.1371/journal.ppat.1004684 · 2015 · External reference

CK1δ and CK1ε Signaling Sustains Mitochondrial Metabolism and Cell Survival in Multiple Myeloma

10.1158/0008-5472.can-22-2350 · 2023 · External reference

Translational profiling of macrophages infected with Leishmania donovani identifies mTOR- and eIF4A-sensitive immune-related transcripts

10.1371/journal.ppat.1008291 · 2020 · External reference

Impact of Leishmania infection on host macrophage nuclear physiology and nucleopore complex integrity

10.1371/journal.ppat.1004776 · 2015 · External reference

From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity

10.1128/aac.00021-16 · 2016 · External reference

Investigating the C2 Modulation of the Imidazo[1,2-a]pyrazine-Based Hit Compound CTN1122: Synthesis, in vitro Antileishmanial Activity, Cytotoxicity and Casein Kinase 1 Inhibition

10.1002/cmdc.202400862 · 2025 · External reference

Pharmacophore-guided optimization of the hit compound CTN1122 in the design of promising imidazo[1,2-a]pyrazine derivatives targeting the casein kinase 1 for antileishmanial therapy

10.1039/d5md00257e · 2025 · External reference

REVIGO summarizes and visualizes long lists of gene ontology terms

10.1371/journal.pone.0021800 · 2011 · External reference